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Available online at www.sciencedirect.com

British Journal of Oral and Maxillofacial Surgery xxx (2015) xxx–xxx

Review
Recent advances in the management of oral and
maxillofacial trauma
Rory C. O’Connor a,∗ , Kaveh Shakib b , Peter A. Brennan c
a Specialist Registrar in Oral and Maxillofacial Surgery, Nottingham University Hospitals NHS Trust, Queen’s Medical Centre, Derby Road, Nottingham,
NG7 2UH
b Consultant Oral and Maxillofacial Surgeon, The Ridgeway, Enfield, Middlesex, EN2 8JL
c Consultant Oral and Maxillofacial Surgeon, Portsmouth Hospitals NHS Trust, Queen Alexandra Hospital, Southwick Hill Road, Cosham, PO6 3LY

Accepted 20 August 2015

Abstract

This review summarises recently published papers on maxillofacial trauma in 2 widely read journals: the British Journal of Oral and Max-
illofacial Surgery (BJOMS) and the International Journal of Oral and Maxillofacial Surgery (IJOMS). Since a large proportion of the injuries
seen in oral and maxillofacial surgery (OMFS) departments are fractures of the facial skeleton, we primarily focus on their assessment and
treatment, but also cover problems that affect the temporomandibular joint (TMJ) (including ankylosis), military injuries, polytrauma, and the
use of perioperative drugs. Between 2012 and 2013, 121 articles were published in the 2 journals. Most of the research concerned mandibular
fractures, particularly those involving the condyle, but epidemiological studies and midfacial fractures were also well represented. Even though
the incidence of facial injury is high, it is difficult to collect data particularly when long-term evaluation is required, as rates of compliance
and attendance at follow up tend to be low. The number of large-scale studies was therefore small. A concerted effort to collaborate nationally
and across specialties to undertake larger studies will help to improve outcomes.
© 2015 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Keywords: Facial trauma; Review; Fracture; Mandible; Condyle; Ankylosis

Introduction of facial injuries, and future areas that require development,


we have summarised articles pertinent to OMFS trauma
The assessment and management of patients with facial published between 2012 and 2014 in 2 of the leading jour-
injuries is a core part of the workload of the Oral and Max- nals with the highest impact factors in the field, the British
illofacial surgeon. The treatment of many injuries has now Journal of Oral and Maxillofacial Surgery (BJOMS) and
been standardised, but techniques and technology evolve, the International Journal of Oral and Maxillofacial Surgery
and in some areas, such as the treatment of condylar frac- (IJOMS). The review is designed to be an educational
tures, there is conflicting evidence, and in others there is no resource, not an all-encompassing review to answer a specific
evidence at all. To gain an insight into the current contro- question.
versies about treatment, new approaches to the management Between the 2 journals, 121 articles relating to trauma
were published (Tables 1 and 2). The low number of prospec-
tive and randomised controlled trials has been highlighted

Corresponding author. Tel.: +0115 969 1169; fax: +0115 9627939. previously,1 and this trend seems to be continuing. Mandibu-
E-mail addresses: roaroconnor@gmail.com (R.C. O’Connor),
lar trauma is a popular topic but other regions, including the
k.shakib@shakib.org (K. Shakib), peter.brennan@porthosp.nhs.uk
(P.A. Brennan). frontal bone and temporomandibular joint (TMJ), are less

http://dx.doi.org/10.1016/j.bjoms.2015.08.261
0266-4356/© 2015 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
Maxillofac Surg (2015), http://dx.doi.org/10.1016/j.bjoms.2015.08.261
YBJOM-4599; No. of Pages 9
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2 R.C. O’Connor et al. / British Journal of Oral and Maxillofacial Surgery xxx (2015) xxx–xxx

Table 1
Articles on facial trauma published in the British Journal of Oral and Maxillofacial Surgery in 2012-2013 according to anatomical region.
Review Meta-analysis/ RCT Prospective Retrospective Case report/ technical note Letter Total
Mandible - 1 9 7 9 - 26
Midface 1 1 - 4 8 - 14
Frontal - - - 1 2 - 3
TMJ 1 - 1 1 2 1 6
Pan facial 1 - 5 4 - 2 12
Other 3 - 2 2 - - 7
Total 6 2 17 19 21 3 68

Table 2
Articles on facial trauma published in the International Journal of Oral and Maxillofacial Surgery in 2012-2013 according to anatomical region.
Review Meta-analysis/ RCT Prospective Retrospective Case report/ technical note Letter Total
Mandible - 1 8 9 4 4 26
Midface - - 3 6 1 4 14
Frontal - - 1 - 1 - 2
TMJ - - - 1 - - 1
Pan facial - - - 4 1 - 5
Other 1 - 1 - - 3 5
Total 1 1 13 20 7 11 53

Table 3
General key points.
Young men have the highest risk of facial injury because of interpersonal violence and sport. Alcohol and drug abuse are implicated in 15%-40%, and
47% of injuries, respectively
Children from the lowest socioeconomic group are 1.89 times more likely to sustain a facial injury than those from the highest group
Falls are the most common cause of facial injury in people over 60 and cause a large proportion of the total number of facial injuries
No more than 24 hours of postoperative antibiotics are necessary after repair of orbital and mandibular fractures as longer courses do not reduce
infection rates further
Perioperative steroids reduce postoperative nausea, vomiting, and swelling, and do not seem to impair healing through immunosuppression
Emergency access to theatre is inadequate for patients with facial injuries and 30% of cases are delayed because others are more urgent
The incidence of serious complications in patients with facial injuries who are operated on out-of-hours is over 3 times that of those operated on
in-hours

Table 4
Key points: mandibular fractures.
Cortical bone in the parasymphyseal region may be less than 4 mm thick, so the stabilisation of fractures with screws longer than 4 mm may injure the
apicies of the teeth
It is not necessary to remove a wisdom tooth that complicates a fractured mandibular angle as postoperative infection rates are the same (11%)
whether it is removed or not
For fractures of the angle, the incidence of plates being removed secondary to infection is higher if the plate was placed on the external oblique ridge
than on the buccal aspect of the mandible (OR 5.05)
Stress tests suggest that osteosynthesis of a fractured mandibular condyle should be done with 2 plates, as one is not sufficiently stable
Animal and histological studies have shown that resorbable poly D,L-lactide plates and pins are suitable tools in the fixation of condylar fractures, but
further evaluation in humans is required

Table 5
Key points: midfacial and orbital fractures.
Children with fractures of the orbital floor are at risk of muscular incarceration because of the trapdoor effect of the bone at the fracture site; this
requires prompt surgical release within 24-48 hours to prevent permanent visual disturbance
Fractures of the orbital wall may be treated conservatively if the defect is small (less than 3cm2 ), with little enophthalmos (less than 2 mm) and if there
is no entrapment of periorbital tissue
Cannulation of the lacrimal duct with a silicone catheter can protect the lacrimal appartus during repair of naso-orbitoethmoidal fractures

Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
Maxillofac Surg (2015), http://dx.doi.org/10.1016/j.bjoms.2015.08.261
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Table 6
Key points: nasal and frontal fractures.
An intraoperative anterior ethmoidal nerve block with infiltration of the dorsum of the nose provides good postoperative analgesia in patients
undergoing reduction of nasal fractures
Cranialisation or obliteration of the frontal sinus may be required if there is evidence on computed tomography of a fracture of the sinus floor or
medial wall of the anterior table, or an outflow obstruction, as they suggest blockage of the nasofrontal duct
Fractures of the anterior table of the frontal sinus may be accessed and repaired endoscopically by suitably trained surgeons with the incisions hidden
behind the hairline

Table 7
Key points: temporomandibular joint (TMJ).
Trauma is the most common cause of ankylosis of the TMJ particularly if sustained under the age of 5
Ossification of a haemarthrosis, intra-articular damage to the disc, aberrant lateral pterygoid pull, and periarticular soft tissue injury, have been
implicated in the development of ankylosis
For soft tissue injuries, magnetic resonance imaging (MRI) is the imaging of choice as it shows displacement of the disc and damage to the articular
surface not evident on plain radiographs or computed tomography
Treatment for ankylosis is not standardised. Simple excision (with or without arthroplasty), condylectomy with resurfacing of the joint with a
costochondral graft, and osteotomies have been described but none are free from recurrence

well represented. Most publications included are full-length Alcohol was implicated in 15%-40% of facial injuries,3,4,7
articles. Short communications and letters were included only and in Scotland the incidence of facial injuries in children that
if they added to the knowledge. Tables 3 to 7 highlight key are related to alcohol has not improved in a decade.8 O’Meara
points of management for each anatomical region. et al found that patients with facial fractures were more likely
to need an operation if they had consumed alcohol within the
preceding 8 hours, or were victims of interpersonal violence,
Epidemiology of facial trauma with relative risks of 1.61 and 3.10, respectively.9
McAllister et al found that 44/93 (47%) of those admit-
A total of 325 patients with facial injuries attended accident ted for facial injuries had evidence of illegal drugs in their
and emergency (A&E) departments in the west of Ireland over urine.7 Cannabinoids and benzodiazepines were most often
one week (5.2% of attendances), and the annual incidence detected. Both alcohol and drugs were found in 17% of cases,
was 1619/100 000.2,3 Men were injured more than women although 32/44 patients whose toxicology results were pos-
(68% compared with 32%), and half of all patients were aged itive denied substance abuse. Reluctance to admit to using
between 15 and 45. The commonest causes were falls (39%) drugs has implications for general anaesthesia and analgesia.
and sporting activities (29%). Fractures accounted for 25% Patients with facial injuries often have other injuries on
of presentations, and 65% of those affected were male. The the head and limbs (19%-30% and 22%-25% of associ-
commonest sites were the nose (50%), mandible (25%), and ated injuries, respectively), which can prolong their stays in
zygoma (12%). hospital.3,4 In a review of the management of traumatic brain
In a Dutch trauma centre over a 6-year period, 394 patients injuries, Tsang and Whitfield reported that 24% of patients
with facial fractures required an operation.4 The male:female with craniofacial fractures also had fractures in the base of
ratio was 3:1 with a peak incidence in young men (35% of the skull, which were complicated by the leakage of cere-
fractures). Forty-two percent were caused by car crashes. brospinal fluid in 20%.10 Leaks can be treated conservatively,
Interpersonal violence and sports caused more injuries in men but antibiotics are not recommended.
than in women (ratios of 9.5:1 and 8.2:1, respectively), and A total of 45 388 children (0.5% of the population) with
mandibular and zygomatic fractures accounted for more than facial injuries required admission in Scotland over 10 years,
80% of the total. In another trauma centre the characteristics giving an incidence of 4.7/1000.8 Injuries occurred more
of patients with facial injuries sustained in the workplace often in boys (6.21/1000) than in girls (3.20/1000), while
were similar to those of the general population with young, children younger than 2 years and those aged 15-17 were
male, manual workers most commonly affected.5 most likely to be affected. Poor coordination in young chil-
Rashid et al analysed 1261 patients with 1994 mandibular dren when learning to walk predisposes them to falls, and
fractures in London over 5 years.6 The male:female ratio was in older children, risk-taking behaviour and use of alcohol
6.6:1 with peak incidences in the third decade for both sexes, increase the chance of injury. In another series, 91/325 (28%)
and a smaller peak in women over 70. Most of the fractures in of presentations to A&E were children under the age of 14.2
men were caused by interpersonal violence (77%) and falls As children from the lowest socioeconomic group are 1.89
(18%), but in women falls were the most common cause. The times more likely to be injured than those in the highest,8
incidence of fractures associated with road traffic accidents public health programmes designed to reduce the number of
(4%) was low, which reflects the improvements in car safety. facial injuries should be aimed at this group.

Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
Maxillofac Surg (2015), http://dx.doi.org/10.1016/j.bjoms.2015.08.261
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In a prospective, observational study that compared facial complicated the fracture site, postoperative infection rates
injuries in those under and over the age of 60, Velayutham were 11% whether the tooth had been removed (84/788) or
et al found that falls were the most common cause in the not (84/754).19
older group (40/470, 9%), and the site most commonly Titanium miniplates are usually used to fix fractures of
fractured was the zygoma, which could often be managed the angle, but malleable plates are also available, which are
conservatively.11 However, 17/34 patients who fell were tak- half the volume and more pliable. In a biomechanical study
ing 5 or more drugs, which suggests an association between on sheep, fractures of the angle were stabilised using mini-
polypharmacy and falls. As falls were also found to be the plates or malleable plates on the external oblique ridge.20 The
leading cause of facial injury in patients over 60 in 2 other malleable plates, which fractured above 90 newtons (less than
series,2,6 those at risk should be enrolled in prevention pro- occlusal biting force) and showed more vertical displacement
grammes. than miniplates when loaded at lower forces, were considered
unsuitable. An alternative to fixation of the external oblique
ridge is plating of the buccal aspect of the mandible below the
Mandibular fractures ridge. A randomised prospective trial found that more ridge
plates (28/137, 20%) than buccal plates (6/124, 5%) had to be
Symphyseal and parasymphyseal fractures removed because of infection (odds ratio 5.05).21 Smoking,
preoperative displacement of bony fragments by more than
For parasymphyseal fractures, osteosynthesis plates should 5 mm, and postoperative malocclusion, were also associated
be placed below the apices of the teeth but above the mental with infection.
foramen. De Souza Fernandes et al assessed the thickness of Favourable and unfavourable patterns of angle fractures
cortical bone, and the interapical distance of canine, first, and have been described in which the pull of the masticatory
second premolar teeth in cadavers.12 Roots were present at muscles either reduces or distracts the fracture. Pektas et al
the level at which the plate was fixed but a 2 mm diameter compared osteosynthesis of the 2 patterns using titanium
screw could be used as there was more than 3 mm between miniplates placed buccally in sheep.22 There was no dif-
them. The buccal cortex was less than 3 mm wide, thinner ference between the groups in the distance the fracture was
than that reported to be necessary for stabilisation. Al-Jandan displaced under loading, and maximal breakage forces were
et al found that the buccal bony depth was 3.1 - 3.7 mm in similar, which suggested that the fracture pattern should not
the canine and premolar region, and the predicted risk of affect the operative technique.
damaging the apex of the tooth during insertion of a screw Chen et al compared the use of resorbable poly-L-lactide
4 mm long was 30%, 18%, and 38% for canine, first, and screws (reinforced with polyglycolic acid fibres) with tita-
second premolars, respectively.13 More studies are required nium and non-reinforced resorbable screws to fix sagittal
to find out whether the minimum thickness of bone needed split fractures in pigs.23 Shear and torsional strength were
to stabilise a parasymphyseal fracture could be reduced. greater in the reinforced poly-L-lactide screws than the non-
Mandibular fractures in children can be managed using reinforced screws, and there was no difference in breakage
custom-made acrylic or acrylic and steel-wire splints,14,15 force for each screw. In vivo testing is now required.
which are made using impressions taken under general anaes-
thesia and secured with circum-mandibular wires. However, Condylar fractures
the technique is not suitable for fractures of the angle.
For condylar fractures, consensus has moved towards open
Fractures of the mandibular angle reduction and internal fixation (ORIF) with transoral or trans-
buccal access. Yang and Patil described a retromandibular
Buried or partially erupted third molars may weaken the angle transparotid approach,24 but despite meticulous dissection
because they reduce the area of bone, but in 190 patients no of the facial nerve during parotid transit, 8/42 patients
association was found between the degree of eruption and experienced transient weakness, and 3/42, a salivary fis-
fracture.16 The presence of the tooth alone caused weak- tula. Narayanan et al used a transmasseteric anterior parotid
ness and predisposed the bone to fracture. Three-dimensional approach instead,25 and functional occlusion was achieved
finite element reconstruction of human mandibles has been in all patients with no facial weakness. By passing anterior
used to find out whether the presence of third molars weakens to the parotid, a window is created by the divergence of the
the angle.17 The technique converts geometrically complex buccal and zygomatic branches of the facial nerve.25,26 Pau
structures into simple shapes that are more easily examined et al used a transtragal incision, which combined preauricu-
to approximate structural behaviour.18 lar and aural incisions to detach the tragal cartilage, to allow
When a third molar is present, stress is concentrated at deeper exposure of the fracture site.27 Although the carti-
the angle of the mandible, but is transferred to the condyle lage was separated it did not become infected or necrotic.
if absent, leading to fractures here instead.16,17 The removal The cartilage of the external auditory canal may also be
of teeth in the fracture line has long been debated, and in a detached to expose fractures using the retroauricular trans-
meta-analysis of 1542 fractures of the angle in which teeth meatal approach, which hides the scar behind the ear.28

Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
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Endoscopic stabilisation of condylar fractures has been cases even if a malocclusion develops, as it does not always
tested in minipigs.29 Operating times for a novice improved result in functional deficit or pain. However, 30 patients,
from 183 minutes to around 50 minutes after 10 procedures including 4 treated with osteotomy or orthodontics for a
had been completed, equalling that of an experienced sur- malocclusion, were lost to follow up. The dentures of a 61-
geon. year-old man with bilateral condylar fractures were secured
Fixation of condylar fractures has been evaluated using to his maxilla and mandible so they could act as splints during
photoelastic stress analysis on mandibular resin models to healing.41
show areas of tension and compression by the diffraction of
light passing through the material.30 Fractures fixed using a
single miniplate were not sufficiently stable, but stability was Midfacial and orbital fractures
comparable to controls when 2 miniplates or one miniplate
and a microplate were used. Finite element analysis of human Orbital fractures account for 45%-56% of all facial fractures
mandibles also showed that 2 miniplates were better than in children.42 The orbital roof is more likely to fracture than
one.18 Distraction of the fragments using one miniplate, 2 the floor in children younger than 7 because of the protuber-
non-parallel, and 2 parallel plates, was 115 ␮m, 46 ␮m, and ance of the frontal bone, but muscle entrapment in a fracture
30 ␮m, respectively. The mean stress in the plates and screws of the orbital floor necessitates urgent decompression. This
was 2.5 - 3.0 times greater when one miniplate (rather than is because the trapdoor-type pattern predominates in patients
2) was used. Interestingly, 2 parallel miniplates led to less under 16 because of bony plasticity, which allows the floor
bony distraction and stress than the non-parallel arrangement. to hinge rather than break.43 Once the trapdoor springs back,
When the fragments of a subcondylar fracture overlap, Gahir periorbital tissue becomes incarcerated in the fracture site and
et al suggested inserting a screw in the mandibular angle causes diplopia and restricted eye movement. The oculovagal
around which a wire can be hooked to provide traction along reflex, which causes nausea and vomiting from traction on the
the axis of the ramus.31 extraocular muscle or pressure on the globe, suggests entrap-
Anatomical reduction is necessary when treating intracap- ment. The trapped tissue becomes ischaemic, and warrants
sular condylar fractures, as loss of articular cartilage has been repair within 24-48 hours.42,43 Diplopia and restricted eye
shown to distort growth and reduce the height of the ramus in movement are less common in blowout fractures as the bone
animals.32 Computer-aided design (CAD) using reformatted breaks completely, so it is suggested that they are repaired
computed tomography (CT) can simulate the reduction of a within 3 days.43
fracture and guide the length and placement of screws.33–35 Kunz et al assessed functional outcome in mild to moder-
Schneider et al used resorbable poly D,L-lactide plates ate fractures of the orbital wall to find out whether indications
secured with resorbable ultrasound-activated pins, and pins to operate could be based on the site, size, and pattern of
alone, to treat condylar neck and intracapsular fractures in fracture.44 Only enophthalmos correlated with the size of the
sheep, respectively.36,37 Performance was comparable to tita- defect, whereas diplopia resolved in all patients, which made
nium screws, and macroscopic and histological evaluation it a less reliable indicator. Fractures of the orbital wall can
found little inflammatory infiltrate at the pin sites, normal be treated conservatively when the defect is less than 3 cm2 ,
bony healing, and complete resorption at 12 months. and when enophthalmos is less than 2 mm and no soft tissue
Resorbable screws were used to fix intracapsular condy- or muscle is trapped.
lar fractures in 19 patients.35 Normal occlusion and mouth Hundepool et al found that endoscopically-controlled
opening were restored in 18 of them, and there were no long- reduction of fractures of the orbital floor improved enoph-
term complications. A resorbable mesh of the same material thalmos and diplopia when compared with controls because
secured with ultrasound-activated resorbable pins was used it allowed visualisation of the entire defect.45 Even when
to treat 5 patients with fractures of the condylar neck.38 the orbit is reduced completely, diplopia can persist because
Singh et al reported 12 patients whose condylar fractures of adhesions from tethered scar tissue. Insertion of allo-
were fixed with one resorbable plate.39 In 6 the result was geneic amniotic membrane is a potential solution as it is not
satisfactory, but in the other 6 the plate failed intraoperatively adhesive.46
and had to be replaced or reinforced by a titanium plate, or Custom-made polyetheretherketone implants, constructed
the patient put into intermaxillary fixation (IMF). Also, 7 in 2 parts to enable each component to be inserted
screws broke. Since one titanium plate is not sufficient, one along a different path, have been tested for reconstruction
resorbable plate will be unstable too. of orbitozygomatic fractures.47 Reduction of comminuted
The condyle is the most common part of the mandible orbitozygomatic and nasofrontal fractures is easier with
to fracture bilaterally,6 and complications are more severe. screw-wire traction.48,49 A stainless steel wire, which is
Forouzanfar et al evaluated outcomes in patients with bilat- twisted to form a tight coil with a loop at the end, is hooped
eral condylar fractures who were treated conservatively with over a screw in the fragment of bone to enable it to be reposi-
IMF for 6 weeks.40 Overall, 9/71 (13%) developed a maloc- tioned. Depressed fractures of the zygomatic arch can also be
clusion and none had pain in the TMJ, but only 41/71 (58%) reduced with wires inserted percutaneously if looped around
had long-term follow up. IMF seems to be appropriate in these the arch.50 Circumzygomatic wires were used to suspend a

Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
Maxillofac Surg (2015), http://dx.doi.org/10.1016/j.bjoms.2015.08.261
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loose maxillary obturator in a patient with a contralateral Le Damage to the soft tissue around the joint without frac-
Fort I fracture to permit feeding during healing.51 ture can also lead to ankylosis, osteoarthritis, and internal
Iwai et al investigated whether intubation of the lacrimal derangement of the disc.61 In 8 patients, magnetic resonance
system with a silicone tube during ORIF of displaced naso- imaging (MRI) showed displacement of the disc and destruc-
orbitoethmoidal fractures prevented ductal blockage and tion of the articular surface not evident on CT or radiograph.
epiphora.52 Cannulation was successful in 13 patients and If caught early, symptoms can be treated with arthroscopic
none had epiphora, but care must be taken during cannulation lysis and lavage before the joint degenerates. Yu et al used
to prevent damage to the ductal system. MRI to show soft tissue injuries to the TMJ in 18 patients with
19 intracapsular condylar fractures.62 It confirmed displace-
ment of the disc (n = 15), tears in the capsule (n = 9), and tears
in the retrodiscal tissue (n = 16). All 19 had joint effusions,
Nasal and frontal fractures
16 of which were haemarthroses. Their findings suggest that
MRI is the best imaging technique for these injuries.
Yilmaz et al evaluated closed reduction of nasal fractures
Operations for ankylosis are reserved for patients with
in 24 children.53 At 6 months 15/24 were satisfied with the
chronic pain and restricted mouth opening. Some surgeons
result. Nine were not, and of them, 8 would consider an
excise the ankylotic mass while others do an arthroplasty or
operation to improve cosmesis. More patients were satisfied
osteotomy.59 He et al did a high condylectomy and resurfaced
when the reduction was done within 5 days of injury (12/16)
the joint with a costochondral graft, but also repositioned a
than after (3/8), but satisfaction was not clearly defined. An
displaced disc.61 However, there is always a risk of recur-
anterior ethmoidal nerve block with percutaneous infiltration
rence. Kanatas et al used a 2-stage procedure in which the
of the dorsal nose given during reduction of nasal fractures
ankylotic mass was removed and the joint reconstructed later
provides excellent pain relief and reduces the need for post-
with a prosthesis.63 Persistent dislocation has been treated
operative analgesia.54
with condylotomy to separate the dislocated condyle from
In fractures of the frontal sinus, 3 findings on CT suggest
the mandible.64
obstruction of the nasofrontal duct: fractures of the sinus floor
or medial wall of the anterior table, and obstruction of the
outflow.55 If all 3 are present, there is a serious risk of injury
to the outflow tract with a positive predictive value of 81%, so Military injuries and polytrauma
cranialisation or obliteration of the sinus is required. When
CT shows no evidence of obstruction the nasofrontal duct Breeze et al proposed a framework for the development of
may be intact, which permits preservation and reconstruction military neck protection after an increase in the number of
of the frontal sinus. cervical injuries in the British forces.65 From 2006-2010,
Fractures of the anterior table can be accessed endoscop- explosions caused 79% of neck injuries, of which 41% were
ically with incisions above the hairline.56 Rao et al plated a fatal. Deaths resulted from serious injuries to the vessels or
fracture above the supraorbital rim through an incision in the spinal cord, so any neck injury model should incorporate
upper eyelid crease.57 They inserted screws using a 90◦ drill these structures. This should be coupled with a system that
and screwdriver, and smoothed the defect in the contour with maps surface wounds and records those caused by projectiles.
calcium phosphate cement. Analysis of fragments removed after injury enables better
understanding of their behaviour, but it is difficult to iden-
tify every piece, and removal is not always possible. CT can
Temporomandibular joint locate and characterise fragments left in place to increase
sample sizes for modelling,66 and computer programs can
Trauma was the most common cause of ankylosis, partic- then simulate how structures in the neck respond to projec-
ularly if sustained before the age of 5 years.58 Patients tiles, which can inform the design of a prototype. The British
with sagittal condylar fractures and those from developing OSPREY neck collar is not worn widely so development has
countries were more likely to develop ankylosis because of begun to interweave ballistic material into the collars of body
malnutrition, poor access to healthcare, the cost of treatment armour shirts.65
and untreated infections.58,59 Panfacial injuries cannot be categorised in the same way
Ossification of a haemarthrosis, or damage to the intra- as isolated fractures, particularly when they traverse differ-
articular disc have been proposed as causes of ankylosis.59 ent anatomical regions. Ahmad et al proposed a classification
In sheep Liu et al found that bony overgrowth occurs in the based on existing scoring techniques.67 The “ZS” maxillo-
condylar head following a sagittal fracture.60 The degree facial trauma scoring system, which combined and modified
of overgrowth was reduced if the attachment of the lateral 4 existing systems, correlates well with current methods and
pterygoid was cut, suggesting that the pull of the muscle con- has good interobserver and intraobserver reliability (0.98 and
tributes to the remodelling of bone post fracture, which can 0.99, respectively), but requires refinement to incorporate soft
result in overgrowth and subsequent ankylosis. tissue injuries.

Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
Maxillofac Surg (2015), http://dx.doi.org/10.1016/j.bjoms.2015.08.261
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Perioperative antibiotic and steroid prophylaxis Although 90% of eye injuries are preventable, the uptake of
protective eyewear is poor even in high-risk sports.
Antibiotic prophylaxis in facial trauma is haphazard as pro- Thermoplastic splints manufactured using 3-dimensional
tocols vary between hospitals and depend on the preference scans of the face allow a quicker return to contact sport for
of the surgeon. Two randomised, double-blind, placebo- players with a facial fracture, as the images can be manip-
controlled, single centre studies provided a foundation for ulated to add areas of relief around the fracture before the
standardisation. In the first, which assessed antibiotic regi- manufacture of a physical model.73
mens in patients who required repair of orbital fractures,68
amoxicillin with clavulanic acid was given intravenously
from admission to 24 hours postoperatively. The experimen- Service provision for facial trauma
tal group had 4 further days of the drug and the control a
placebo. There was no difference in infection rates between Sherman and Kouchard developed a proforma for the assess-
the groups. The second study involved patients who had ment of patients with facial injuries to improve both the
ORIF for mandibular fractures.69 The antibiotic protocol was quality of the documentation and communication with
identical to the first study but patients were also prescribed colleagues.74 Data collected from the proformas can be used
chlorhexidine mouthwash. There was no difference in infec- to guide service provision.
tion rates between patients who had one day as opposed to Access to emergency theatres in OMFS is poor because
5 days of antibiotics. The infection rate was higher (8/32) injuries are not life-threatening. In a prospective UK audit,
when teeth were in the fracture line, than when they were operations in 67/222 of patients (30%) were delayed,75
not (4/27), but this has not been confirmed elsewhere.21 Both mostly because other cases were more urgent. Bertram
studies lacked statistical power, many eligible patients were et al found that more serious complications occurred
excluded, and the duration of preoperative antibiotics varied, when patients were operated on out-of-hours (7/53, 13%)
but as wide-ranging definitions of infection were employed, than when operations were done in-hours (3/81, 4%),
infection rates were accurate. although there was no difference in the incidence of minor
A prospective multicentre audit evaluated infection rates complications.76 Dedicated trauma lists would solve these
in patients who had fixation of mandibular fractures.70 In problems.
the first cycle, antibiotics were given for 3-5 days postopera-
tively, and the infection rate was 10% (15/145). In the second,
antibiotic regimens were standardised to finish 24 hours post-
operatively, and 9% (14/157) had infections. Repairs of Conclusion
orbital and mandibular fractures are clean-contaminated pro-
cedures so there is a risk of infection without antibiotics, but Although the incidence of facial trauma is high, the num-
evidence suggests that only 2 postoperative doses should be ber of large-scale trials is disappointing. Randomisation is
given. often impossible, and most studies included less than 100
Perioperative glucocorticoids reduce nausea, pain, and patients. The management of condylar fractures has devel-
swelling, but also suppress immunity, which may impair oped, and resorbable osteosynthesis is a future avenue for
healing. In a randomised single-blind trial of patients who research. Collaboration in larger-scale trials would improve
required ORIF for fractured mandibles, healing was impaired outcomes, not just between departments, but nationally and
no more in those who were given dexamethasone periop- across different specialties.
eratively (7/20) than in controls (6/21).71 Interestingly, all
patients were given antibiotics for between 7 and 10 days
postoperatively. Age over 25 was associated with impaired Conflict of Interest
healing but smoking, delayed treatment, and duration of oper-
ation, were not. We have no conflicts of interest.

Sports injuries
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Please cite this article in press as: O’Connor RC, et al. Recent advances in the management of oral and maxillofacial trauma. Br J Oral
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