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ABSTRACT
Aim: To study relation of headache with sinusitis and its management. Material and methods: Patients clinically presenting
with headache were selected. Only patients with headache due to rhinogenic causes were subjected to X-ray paranasal sinuses
(PNS) and diagnostic nasal endoscopy (DNE) and were followed up to evaluate management. Results: Majority of the patients
were of age group 21-30 years and it is more predominant in males. Majority of the patients with headache had deviated nasal
septum (DNS) (28.9%), acute sinusitis (28.9%), osteomeatal complex disease (24.63%); few patients had nasal polyp (8.69%),
allergic rhinitis (5.79%) and rarely patients had atrophic rhinitis (2.89%). Headache was localized in forehead (43.4%), more than
one site (34.7%) in majority of cases and few number of patients had headache at glabella (13.04%) and top of head (8.69%).
Majority of the patients who underwent antral washout were not relieved, so they underwent functional endoscopic sinus
surgery (FESS), which gave dramatic results in improving symptoms including headache. Conclusions: Headache is nearly a
universal human experience. The lifetime incidence of headache is estimated to be at least 90%. To know whether the headache
is sinogenic or not, the patient is first assessed clinically and then radiological investigations (X-ray PNS) are done. Role of
FESS is huge and ultimately it is FESS that is the cure for headache due to rhinogenic causes.
Keywords: Headache, sinusitis, FESS
H
eadache is nearly a universal human headache disorders as defined by the International
experience. The lifetime incidence of headache Headache Society are migraine, probable migraine,
is estimated to be at least 90%. Moskowitz has tension type and cluster headache.1
described headache as the symptom produced by the The term ‘sinusitis’ refers to a group of disorders
nervous system when it perceives threat and as such characterized by inflammation of the mucosa of the
is considered part of the protective physiology of the paranasal sinuses (PNS). Because the inflammation
nervous system. When the cause of headache is a nearly always also involves the nose, it is now generally
definable underlying pathologic process, the headache accepted that ‘rhinosinusitis’ is the preferred term to
is diagnosed as a secondary headache. Causes include describe the inflammation of the nose and PNS.2
metabolic, infectious, inflammatory, traumatic,
neoplastic, immunologic, endocrinologic and vascular Patients with chronic headache pain often present
entities. to a variety of specialists, including their primary
care physician, neurologist, dentist, otolaryngologist
When no clear pathologic condition can be identified, and even a psychiatrist. They may present to
headache is considered to be a manifestation of a otolaryngologist because they or their physician
primary headache syndrome. The common primary believe the headache to be related to underlying sinus
pathology. The primary focus of the otolaryngologist is
to exclude this possibility.
*Assistant Professor The diagnosis of headache secondary to acute sinusitis
Dept. of Physiology
†Assistant Professor can be relatively straightforward. Diagnosing headache
Dept. of ENT related to chronic sinus disease can be much more
MM Institute of Medical Sciences and Research difficult depending on patient’s presentation.3
Mullana, Ambala, Haryana
Address for correspondence Endoscopic techniques are now well-established.
Dr Amanpreet Singh
Assistant Professor In combination with modern imaging techniques
Dept. of ENT particularly computed tomography (CT), these
MM Institute of Medical Sciences and Research
Mullana, Ambala, Haryana techniques provide diagnostic possibilities unimagined
E-mail: dr.apsarora@gmail.com a few decades ago.4
Indian Journal of Clinical Practice, Vol. 25, No. 5, October 2014 429
ENT
Mode of onset
16
Duration of complaint
14
Continuous or intermittent 12
No. of cases
Progressive or not 10
8
Site of pain and radiation
6
Type of pain 4
Associated symptoms 2
430 Indian Journal of Clinical Practice, Vol. 25, No. 5, October 2014
ENT
No. of cases
10
DNS - 6 14 - - -
8
Acute
- 8 12 - - - 6
sinusitis
Osteomeatal 4
complex - 7 10 - - - 2
disease
0
Polyp 1 - 5 - - - DNS Acute Osteomeatal Polyp Allergic Atrophic
Allergic sinusitis complex rhinitis rhinitis
- 4 - - - - disease
rhinitis
Rhinogenic causes
Atrophic
- - - 2 - -
rhinitis Figure 3. Sex distribution (rhinogenic causes).
5
Acute sinusitis 8 12
4
3 Osteomeatal 10 7
2
complex disease
1 Polyp 1 5
0 Allergic rhinitis 4 0
5-10 11-20 21-30 31-40 41-50 51-60
Age group (years) Atrophic rhinitis - 2
Migraine Trigeminal neuralgia Tension headache
Temporomandibular joint arthritis
10
Figure 2. Age distribution (others). Male Female
9
8
7
Table 2. Age Distribution (Others) (n = 31)
No. of cases
6
Age group (years)
5
5-10 11-20 21-30 31-40 41-50 51-60 4
Migraine - - 5 - 7 - 3
Trigeminal 2
- - 7 - - -
neuralgia 1
Temporo- 0
mandibular Migraine Trigeminal Temporo- Tension
- - - - 5 - neuralgia mandibular headache
joint
joint arthritis
arthritis Other causes
Tension
headache
- - 4 - 3 - Figure 4. Sex distribution (other causes).
the patients in headache due to other causes were Table 4. Sex Distribution (Other Causes) (n = 31)
females and 6.45% were males (Fig. 4 and Table 4). Male Female
About 28.9% of patients of headache had deviated Migraine 2 10
nasal septum (DNS) and 28.9% of the patients had Trigeminal neuralgia - 7
acute sinusitis, 24.63% of the patients had osteomeatal Temporomandibular joint arthritis - 5
complex disease and 8.69% of patients had polyp,
Tension headache - 7
5.79% of patients had allergic rhinitis and 2.89% of
Indian Journal of Clinical Practice, Vol. 25, No. 5, October 2014 431
ENT
20
Atrophic rhinitis
(2.90%) 18
Allergic rhinitis 16
(5.80%) DNS
(28.99%) 14
Polyp (8.70%)
No. of cases
Osteomeatal 12
complex disease 10
(24.64%)
8
Acute sinusitis 6
(28.99%) 4
2
Figure 5. Etiology of headache with respect to clinical findings. 0
DNS Acute sinusitis (under OMD
antibiotic cover)
Table 5. Etiology of Headache with Respect to Antral washout
Clinical Findings No. of patients Relieved Not relieved
Forehead
Glabella Top of head (8.70%) No benefit Completely
(43.48%)
(13.04%) from surgery free of
(33%) pain (30%)
432 Indian Journal of Clinical Practice, Vol. 25, No. 5, October 2014
ENT
Table 8. Patients Who Underwent DNE (n = 69) had facial discomfort and headache7 and according
to a study conducted by Wolf, 20% of allergy
No. of cases Percentage (%)
patients presented with headache.8 In our study,
Mucosal contact points 30 43.47
out of 69 patients of headache due to rhinogenic
present
causes, 30 (43.4%) patients had headache at forehead,
Mucosal contact points 39 56.52
24 (34.7%) patients had headache at more than one site,
absent
nine (13.04%) patients had headache at glabella and
six (8.69%) patients had headache at top of head. In a
Table 9. Patients Who Underwent FESS due to
study conducted by Kumar et al (2000), localization of
Mucosal Contact Point (n = 25) headache to forehead was 43% while headache at more
than one site was seen in 19%, pain at glabella in 12%
No. of cases Percentage (%)
and at top of head in 9%.5
Total relief from headache 20 80.00
Significant relief 5 20.00 Thus, it can be concluded that headache is localized at
forehead in majority of cases. We also did antral washouts
in our patients of headache but only 35% of the patients
Table 10. Patients Who Underwent FESS due to were relieved. We also did DNE on 69 patients out of
Causes Other than Contact Points (n = 30) which 30 (43%) patients had mucosal contact points.
No. of cases Percentage (%) Patients due to mucosal contact points were advised to
Completely free of pain 9 30.00 undergo FESS. Out of 30 patients, 25 patients underwent
surgery. Postoperatively, 20 patients (80%) had total
Significant symptom 11 36.6
improvement
relief from headache, five patients (20%) had significant
relief. Various other studies in literature show similar
No benefit from surgery 10 33.3
the same results. In a study conducted by Behin et al,
23 patients underwent surgical intervention to relieve
Eighty percent of the patients who underwent FESS for the contact points. Eighty-three percent of patients no
headache due to mucosal contact points had complete longer complained of headache. Eight had significant
relief from headache and 20% had significant relief relief.9
(Table 9). Out of 39 patients of headache due to causes In a study conducted by Parsons et al on 34 patients
other than contact point, 30 underwent FESS. Patients who underwent surgery for contact points, a reduction
who underwent FESS for causes other than mucosal in intensity was reported in 91% of patients and
contact points showed 67% improvement in headache reduction in frequency of headache in 85% of patients
and facial pain (Table 10).
postoperatively 35 (5).10 Thus, from our study and the
above mentioned studies, it is clear that majority of
DISCUSSION
the patients who underwent FESS for mucosal contact
According to our study, the majority of the cases of points were totally relieved of their symptoms. The
headache due to rhinogenic causes were males (54%) remaining 39 patients who had pathologies other than
in the age group of 11-30 years. Similar findings were mucosal contact points i.e., DNS, osteomeatal complex
observed in the study conducted by Kumar et al (2000) disease were also advised FESS to get rid of headache.
wherein majority of patients of headache belonged to Out of the 30 patients who underwent surgery, post-
age group 10-30 years and 53% were males.5 Similarly,
operatively, nine (30%) patients were completely free
in a different study by Wenig et al6 and need Lebovics et
of pain, 11 (36.6%) patients had significant symptom
al demonstrated a male predominance of headache due
improvement and 10 (33.3%) patients had no benefit
to acute frontal sinusitis in both adults and adolescents.
from surgery.
While majority of our patients of headache due to
Thus, it showed 67% improvement and correlates
rhinogenic causes had either DNS, acute sinusitis or
osteomeatal complex disease, we also encountered with studies mentioned below: Welge-Leussen et al
patients having nasal polyps (6 patients) allergic conducted a 10-year follow-up of patients who had
rhinitis (4 patients) presenting with headache. undergone FESS. Out of 20 patients, six (30%) patients
Similarly, in the study by de Freitas et al, the remained completely free of pain, seven (35%) had
patients of polyps along with nasal obstruction also significant improvement and seven (35%) received no
benefit from surgery (65% improvement).11
Indian Journal of Clinical Practice, Vol. 25, No. 5, October 2014 433
ENT
In a study conducted in Dept. of Otolaryngology, ÂÂ Headache can occur at any age. But, the highest
Vajira Hospital, Bangkok, Thailand, 16 patients were incidence was noted in the age group 21-30 years
operated on by FESS. Their principal complaint was followed by 11-20 years.
facial pain or headache. Ten patients had no headache ÂÂ Sex incidence is slightly more in males (53.62%).
postoperatively (62.5%) and six patients (37.5%) had a ÂÂ In patients of headache due to sinogenic cause,
reduction in severity.12 20 patients (28.9%) had acute sinusitis, 20 patients
Thus, from the present study and the above mentioned (28.9%) had DNS, 17 patients (24.63%) had
studies, an improvement in headache in 63-67% of osteomeatal complex disease, six patients (8.69%)
patients operated should be expected after the patients had polyps, four patients (5.79%) had allergic
undergo FESS for headache. rhinitis and two (2.89%) had atrophic rhinitis.
ÂÂ Headache was localized to forehead in 30 patients
CONCLUSION (43.4%) and more than one site in 24 patients
(34.7%), at the glabella in nine patients (13.04%)
Sinusitis refers to a group of disorders characterized and at the top of head in six patients (8.69%).
by inflammation of the mucosa of the PNS. Now-a-
ÂÂ Out of 69 patients of headache due to sinogenic
days rhinosinusitis is the preferred term to describe
causes, 57 underwent antral washout, 20 patients
the inflammation of the nose and PNS. Headache is were relieved of their headache and facial pain
nearly a universal human experience. The lifetime (35.08%) and 37 patients (64.9%) were not relieved.
incidence of headache is estimated to be at least 90%.
ÂÂ All the 69 patients underwent DNE out of which
Before treating the headache it should be known if 30 patients (43.47%) were found to have mucosal
the headache is primary (when no clear pathologic contact points.
condition can be identified) or secondary (metabolic, ÂÂ Out of 30 patients of headache due to mucosal
infectious, inflammatory, traumatic, neoplastic, contact points, 25 underwent FESS; of these, 20
immunologic, endocrine, vascular). patients (80%) had total relief from headache and
To know whether the headache is sinogenic or not, five patients (20%) had significant relief.
firstly the patient is assessed clinically, then radiological ÂÂ Out of the remaining 39 patients of headache,
investigations (X-ray PNS) are done. Patients also 30 patients underwent FESS, nine patients (30%)
undergo DNE. Medical line of treatment with had complete relief from pain, 11 patients (36.6%)
antibiotics, antihistamines, anti-inflammatories, nasal had significant symptom improvement, 10 patients
decongestants will be beneficial only in acute cases of (33.3%) had no benefit from surgery. This showed
that 67% of patients had improvement of headache
sinusitis without any anatomical variation.
after undergoing FESS.
Most cases of sinusitis presenting with headache are ÂÂ Endoscopic management of headache due to
acute cases or acute-on-chronic sinusitis. Antral lavage sinogenic causes provides a tool to the surgeon
can be a relief from headache for some patients. by which he can accurately diagnose meticulously
Role of FESS is huge when no obvious clinical and with minimal trauma operate and precisely
abnormality is made out and ultimately it is FESS that provide postoperative care and follow-up.
is the cure for headache due to rhinogenic causes. ÂÂ The use of microdebrider provides an excellent
surgical result with fewer complications and faster
Now-a-days suction irrigation endoscopy should be
healing than traditional techniques in FESS.
used for visual control during surgery. Microdebrider
should be used for FESS as it provides atraumatic REFERENCES
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Indian Journal of Clinical Practice, Vol. 25, No. 5, October 2014 435
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