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Discuss the pathophysiology of the disease.

Who is at risk?

What are the risk for primary relatives of Alzheimer's patients?

What can we do to prevent it?

It is preventable?

What is the pathophysiology related to certain treatments that aide in PREVENTING Alzheimer's
disease?

Are there any trials going on now that are treating these patient's?

Sheng, M., Sabatini, B. L., & Sudhof, T. C. (2012). Synapses and Alzheimers Disease. Cold Spring Harbor
Perspectives in Biology, 4(5). doi:10.1101/cshperspect.a005777

Jin, J. (2015). Alzheimer Disease. Jama, 313(14), 1488. doi:10.1001/jama.2015.2852

Scheltens, P., Blennow, K., Breteler, M. M., Strooper, B. D., Frisoni, G. B., Salloway, S., & Flier, W. M.
(2016). Alzheimers disease. The Lancet, 388(10043), 505-517. doi:10.1016/s0140-
6736(15)01124-1

Feng, J., Huang, R., & Pwee, K. (2010). Pnd3 A Rapid Review Of Economic Evalautions Of Donepezil,
Rivastigmine, Galantamine And Memantine For Alzheimers Disease (Ad). Value in Health, 13(7).
doi:10.1016/s1098-3015(11)73351-4

Hardy, J., Bogdanovic, N., Winblad, B., Portelius, E., Andreasen, N., Cedazo-Minguez, A., & Zetterberg, H.
(2014). Pathways to Alzheimers disease. Journal of Internal Medicine, 275(3), 296-303.
doi:10.1111/joim.12192

Lee, Y., Back, J. H., Kim, J., Kim, S., Na, D. L., Cheong, H., . . . Kim, Y. G. (2009). Systematic review of
health behavioral risks and cognitive health in older adults. International
Psychogeriatrics, 22(02), 174. doi:10.1017/s1041610209991189

Miller, D. K., Morley, J. E., Rubenstein, L. Z., Pietruszka, F. M., & Strome, L. S. (1990). Formal Geriatric
Assessment Instruments and the Care of Older General Medical Outpatients. Journal of the
American Geriatrics Society, 38(6), 645-651.

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