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Medication Card Main (Common) Side Effects:

Generic Name: Levothyroxine Nausea, vomiting, anorexia, diarrhea, cramps, tremors


Trade Name: Eltroxin which are signs of GI sensitivity indicating inappropriate
Drug Classification: dosage of the hormone.
Thyroid Hormones preparation/ Supplementation Adverse Effects:
Therapeutic Uses: Tachycardia, hypertension, palpitations; can be due to
For clients experiencing hypothyroidism and the levothyroxine increasing the workload on the heart
symptoms related to this disorder with the goal of leading to cardiovascular adverse effects, these may be a
restoring the normal hormonal balance by acting as a manifestation of excess thyroid hormone or a sign of
replacement and treatment of hypothyroidism; which the Thyrotoxicosis which is rare.
condition when your thyroid gland produces too little Nursing Implications:
thyroid hormone. Record vital signs; assess apical pulse and blood pressure
Mechanism of Action: prior to and periodically during therapy.
Levothyroxine supplements and allows for all the actions Monitor the patient weight gain which is a part of the
of endogenous thyroid hormone, such as increasing hypothyroidism signs and symptoms. Assess heart rate
metabolic rate of body tissue by influence the growth and and exercise tolerance frequently
maturation of tissues, by promoting glycogen synthesis lab: monitor thyroid function studies. watch for overdose
through increasing the utilization and mobilization of manifested such as hyperthyroidism.
glycogen stores. Evaluation of Effectiveness:
Safe Dose Range and Administration Info: Evaluate the effectiveness in controlling the symptoms of
PO: 25-50 mcg, increase in 12.5-25 mcg at 6- to 8-wk hypothyroidism, monitored side effect for accumulation
intervals. and overdose, evaluate pateitn knowledge about the
Contraindications: medication and side effects.
Hyperthyroidism, recent myocardial infarction, Teach patient about adverse signs to watch out for such as;
cardiovascular disease, uncorrected androgen disorders, the common side effects of inappropriate dosing and
arrhythmias; due to the fact that levothyroxine is cardio cardiac stimulation.
stimulatory meaning that it enhances cardiac function by Client Teaching:
increasing heart rate, these conditions with be a - Notify HCP any weight gain; which would be a
contraindication because of the fear of putting more work sign of the drug not meeting therapeutic effect of
load on the hearth. supplying the the body with the the thyroid
Interactions: (Medication or Food): hormone which is needed for metabolism.
Levothyroxine might increase the effect of warfarin. - Monitor blood pressure as much as possible
The use of Levothyroxine might require an increase in oral - keep all laboratory appointments, this is
hypoglycemic agents when used together. Cardiac problem important to assure that thyroid hormones stay at a
increase with the use of epinephrine and Levothyroxine. hepatic leave.
- taken on an empty stomach at least 30-60 min
before breakfast.

Hodgson, B. B., & Kizior, R. J. (1998). Saunders nursing drug handbook. Philadelphia: Saunders.

McCuistion, L.E., Vuljoin-DiMaggio, K., Winton, M.B., & Yeager, J.J. (2018). Pharmacology: A patient-centered

nursing process approach (9th ed.). St. Louis, MO: Elsevier.

Vallerand, A. H., Sanoski, C. A., & Deglin, J. H. (2015). Davis’s drug guide for nurses (14th ed.). Philadelphia, PA:

F.A. Davis Company.


Medication Card Main (Common) Side Effects:
Generic Name: Glipizide Drowsiness, headache, confusion, visual disturbances,
Trade Name: Glucotrol anxiety, hunger, anorexia, nausea, constipation, diarrhea,
Drug Classification: Antidiabetics abdominal pain; which might be signs and symptoms of
Therapeutic Uses: hypoglycemic reactions
To control hyperglycemia in type 2 diabetes mellitus Adverse Effects:
Mechanism of Action: Hypoglycemia, tachycardia, seizures, coma, respiratory
Lowers blood sugar by stimulating the release of insulin distress aplastic anemia, leukopenia, thrombocytopenia),
from the pancreas and increasing the sensitivity to insulin weight gain
at receptor sites. May also decrease hepatic glucose Nursing Implications:
production. Get vital signs because the drugs increase cardiac function
Safe Dose Range and Administration Info: & oxygen consumption which can lead to cardiac
PO: 5mg/d problems such as dysrhythmias
Contraindications: Give with food to minimize gastric upset
Type 1 diabetes mellitus, diabetic ketoacidosis Monitor serum glucose and glycosylated hemoglobin
Hepatic and renal impairment. periodically during therapy to evaluate effectiveness of
Hypersensitivity. Hypersensitivity to sulfonamides; cross- treatment.
sensitivity may occur. Evaluation of Effectiveness:
Effectiveness may be deceased by concurrent use of Monitor for Blood sugar In acceptable range (70–99
diuretics such as Lasix, this is because the increase mg/dl)
urination caused by the diuretic which than can cause Patent adherence and knowledge about diabetic regiment
decrease availability of the drug in the body by the Teach patient about adverse signs to watch out for.
increases elimination. Client Teaching:
Severe renal disease which can increased risk of - Instruct patient to take medication at same time
hypoglycemia. Infection, stress, or changes in diet may each day.
alter requirements for control of blood sugar. - Take missed doses as soon as remembered unless
interactions: (Medication or Food) almost time for next dose.
Aspirin, oral anticoagulants, MAOIs, sulfonamides, - Do not take if unable to eat. Explain to patient that
cimetidine, NSAIDs, Beta blockers may increase this medication controls hyperglycemia but does
hypoglycemic effect, mask signs of hypoglycemia and not cure diabetes.
Corticosteroids - Review signs of hypoglycemia and hyperglycemia
with patient. If hypoglycemia occurs, advise
patient to drink a glass of orange juice or ingest 2-
3 tsp of sugar, honey, or corn syrup dissolved in
water
- Advise patient to notify health care professional
promptly if unusual weight gain, swelling of
ankles
- May occasionally cause dizziness or drowsiness.
Caution patient to avoid driving or other activities
requiring alertness until response to medication is
known

Hodgson, B. B., & Kizior, R. J. (1998). Saunders nursing drug handbook. Philadelphia: Saunders.

McCuistion, L.E., Vuljoin-DiMaggio, K., Winton, M.B., & Yeager, J.J. (2018). Pharmacology: A patient-centered

nursing process approach (9th ed.). St. Louis, MO: Elsevier.

Vallerand, A. H., Sanoski, C. A., & Deglin, J. H. (2015). Davis’s drug guide for nurses (14th ed.). Philadelphia,

PA: F.A. Davis Company.


Medication Card Main (Common) Side Effects:
Generic Name: Metformin Abdominal bloating, diarrhea, nausea and vomiting,
unpleasant metallic taste
Trade Name: Glumetza
Adverse Effects:
Drug Classification: antidiabetics Hypoglycemia, lactic acidosis, vitamin B12 deficiency,
palpitations
Therapeutic Uses: control hyperglycemia in type 2
diabetes mellitus Nursing Implications:
Administer with meal to minimize GI effect
Mechanism of Action: decreases hepatic glucose Make sure the patient swallows whole and does not crush
production, decreases intestinal absorption of glucose, and or chew the tablet.
improves insulin sensitivity by increasing peripheral Give at the same time every day
glucose uptake and utilization Monitor for signs of hypoglycemia such as abdominal
pain, sweating, headache, tremor, tachycardia and anxiety.
Safe Dose Range and Administration Info: Teach patient about adverse signs to watch out for.
PO: starts with 500 mg twice daily or 850 a day with Advise patients to carry a Medic Alert card, tag, or
meals; increase gradually with the max: 2550 mg/day bracelet that indicates their health problem and the
antidiabetic dosage.
Contraindications:
Metabolic acidosis, dehydration, infection, hepatic Evaluation of Effectiveness:
impaired, chronic alcohol use, renal dysfunction. Monitor Blood sugar in acceptable range (70–99 mg/dl )

Interactions: (Medication or Food) Client Teaching:


Alcohol, iodinated contrast media, digoxin, morphine, - Advice the paitent to discontinue metformin and
procainamide. oral contraceptives, sulfonamides. report immediately if evidence of lactic acidosis
appears; such as unexplained hyperventilation,
muscle aches, extreme fatigue, unusual
drowsiness
- Prescribed diet is principal part of treatment; do
not skip, delay meals and avoid alcohol
- Report persistent headache, nausea,

Hodgson, B. B., & Kizior, R. J. (1998). Saunders nursing drug handbook. Philadelphia: Saunders.

McCuistion, L.E., Vuljoin-DiMaggio, K., Winton, M.B., & Yeager, J.J. (2018). Pharmacology: A patient-centered

nursing process approach (9th ed.). St. Louis, MO: Elsevier.

Vallerand, A. H., Sanoski, C. A., & Deglin, J. H. (2015). Davis’s drug guide for nurses (14th ed.). Philadelphia, PA:

F.A. Davis Company.


Medication Card Main (Common) Side Effects:
Generic Name: Prednisone Insomnia, heartburn, nervousness, abdominal distention,
diaphoresis, acne, mood swings
Trade Name: Sterapred Adverse Effects:
Muscle wasting (in arms, legs), osteoporosis, spontaneous
Drug Classification: corticosteroids fractures, amenorrhea, cataracts, glaucoma, peptic ulcer.

Therapeutic Uses: Nursing Implications:


Suppression of inflammation and modification of the Monitor lab values: May increase serum glucose, lipids,
normal immune response. sodium, uric acid. May decrease serum calcium,
potassium, WBC, hypothalamic pituitary adrenal
Mechanism of Action: Give with food or fluids to decrease GI side effects.
Inhibits accumulation of inflammatory cells at Give delayed-release tablet whole; do not break, crush,
inflammation sites, phagocytosis, lysosomal enzyme dissolve, or divide.
release/synthesis, release of mediators of inflammation. Evaluation of Effectiveness:
Evaluate effectiveness of corticosteroid therapy. If clinical
Safe Dose Range and Administration Info: manifestations have not improved, a change in drug
PO: 5–60 mg/day in divided doses therapy may be necessary.
Continue monitoring for side effects, especially when a
Contraindications: patient is receiving high doses of corticosteroids.
Acute superficial herpes simplex keratitis, systemic fungal Evaluate the patient’s knowledge of the therapy.
infections, varicella, administration of live or attenuated Client Teaching:
virus vaccines. Acute untreated infections. - Teach patient about adverse signs to watch out
for; such as Insomnia, heartburn, nervousness,
Interactions: (Medication or Food) abdominal distention
Hepatic enzyme inducers, Live virus vaccines - Be aware that a slight weight gain with improved
St. John’s wort appetite is expected, but after dosage is stabilized,
a sudden slow but steady weight increase [2 kg
(5lb) per week] should be reported to physician.
- Avoid or minimize alcohol and caffeine may
contribute to steroid-ulcer development in long-
term therapy.
- Report symptoms of GI distress to physician and
do not self-medicate to find relief.
- Do not use aspirin or other OTC drugs unless they
are prescribed specifically by the physician.
- Report slow healing, any vague feeling of being
sick, or return of pretreatment symptoms.
- Be fastidious about personal hygiene; give special
attention to foot care, and be particularly cautious
about bruising or abrading the skin.
- Report persistent backache or chest pain (possible
symptoms of vertebral or rib fracture) that may
occur with long-term therapy.

Hodgson, B. B., & Kizior, R. J. (1998). Saunders nursing drug handbook. Philadelphia: Saunders.

McCuistion, L.E., Vuljoin-DiMaggio, K., Winton, M.B., & Yeager, J.J. (2018). Pharmacology: A patient-centered

nursing process approach (9th ed.). St. Louis, MO: Elsevier.

Vallerand, A. H., Sanoski, C. A., & Deglin, J. H. (2015). Davis’s drug guide for nurses (14th ed.). Philadelphia, PA:

F.A. Davis Company.


Medication Card Main (Common) Side Effects:
Generic Name: Desmopressin Drowsiness, headache, mild abdominal cramp, nausea,
Trade Name: DDAVP, DDAVP Rhinal Tube
Adverse Effects:
Drug Classification: Seizures, hypertension, hypotension, tachycardia, vulval
Therapeutic Uses: an antidiuretic hormone, works by pain, water intoxication hypernatremia
limiting the amount of water that is eliminated in the
urine. Nursing Implications:
check urine specific gravity
Mechanism of Action: Upon binding of desmopressin to assess weight, report sudden increases in weight (can
V2 receptors in the basolateral membrane of the cells of cause water retention
the distal tubule and collecting ducts of the nephron,
adenylyl cyclase is stimulated. The resulting intracellular Evaluation of Effectiveness:
cascades in the collecting duct lead to increased rate of Monitor decrease frequency of nocturnal enuresis
insertion of water channels, the lumenal membrane and Decrease in urine volume
enhanced the permeability of the membrane to water. Relief of polydipsia
Increase urine osmolality
Safe Dose Range and Administration Info: Control of bleeding in hemophilia
PO: Initial dose 0.05 mg bid; then titrate to response.
Client Teaching:
Contraindications: - Notify HCP if blessing is not controlled or if
Hyponatremia, hemophilia A and B, Renal impairment headache, dyspnea, heartburn, nausea, abdominal
cramps accurse
- Teach paitent to avide use of alcohol with this
Interactions: (Medication or Food) medication
Chlorpropamide, clofibrate, chlorpromazine, lamotrigine - For intranasal use the tube should be rinsed under
SSRIs or carbamazepine, tricyclic antidepressants, water after each use
alcohol, heparin, lithium, due to the last 4 medication - Prime the pump prior to first use by pressing
causing decrease in ADH function. down 4 times
- Take missed doses as soon as remembered but not
if it Is almost time for the next dose
- For paitent with diabetes insipidus advice to carry
identification at all times describing disease
process and medication regimen

Hodgson, B. B., & Kizior, R. J. (1998). Saunders nursing drug handbook. Philadelphia: Saunders.

McCuistion, L.E., Vuljoin-DiMaggio, K., Winton, M.B., & Yeager, J.J. (2018). Pharmacology: A patient-centered

nursing process approach (9th ed.). St. Louis, MO: Elsevier.

Vallerand, A. H., Sanoski, C. A., & Deglin, J. H. (2015). Davis’s drug guide for nurses (14th ed.). Philadelphia, PA:

F.A. Davis Company.

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