RESUME SUMMARY STATEMENT

MSc. José Angel Acosta Buxadó, 52

Habana, Cuba

___________________________________________________________________________

PROFESSIONAL EXPERTISE

Center for Genetic Engineering and Biotechnology (CIGB).

2017 - present Market Research, Department of Business Intelligence, CIGB.

2013 – 2017 Business Executive, Heber Biotec S. A. and CIGB.
2004 – 2013 Head of Supervisory Control and Data Acquisition (SCADA) at the CIGB’s
Manufacturing Facility, HVAC, and Critical Systems.
2001 – 2003 Business Executive, Department of Business Development, CIGB.
1994 – 2001 Head of Downstream Processes, Active Pharmaceutical Ingredient of the
recombinant vaccine for integrated control of cattle tick (GAVAC).
Food Industry Research Institute (IIIA)

1992 – 1994 Development of alcoholic fermentation, distillation, and ageing processes.

Design of protein purification processes. Implementation of processes
controls of enzyme manufacturing processes in the food industry.

Food Industry Company “Cervecería Habana”

1991 – 1992 Head of Maintenance at “Cervecería Tropical”

1989 – 1991 Head of Manufacturing at “Cervecería Polar”

FORMAL TRAINING

2017 International Commerce, Ministry of Foreign Commerce.

2012 Production Management
2010 Object Oriented Programing
C++ Programming Language
Social Problems of Science.
2009 Good Engineering Practice
2008 Statistical Analysis of Process
2000 Project Methodology
Biochemistry
Quality Assurance
Scale-up of Biotechnology Process
Economic Engineering
1998 Analytic Techniques
1997 Microsoft Windows 95’
1996 Basic Manufacturing
Good Manufacturing Practice
Professional French Language
1994 Molecular Cell Biology
Scale-up of Biotechnology Process
1990 Professional English Language
1988 Chemical Engineering, Technological University of Havana “José Antonio Echevarría”
(CUJAE), University of Havana, July 1988.

PUBLICATIONS

2017 Market research of a medicine for treatment of fluxion and hemorrhoidal disease.
International Workshop “SiGesTIC’2017”, Hotel Memories, Varadero, 26 – 29
Septiembre 2017.
Market research of a vaccine for lung cancer. International Workshop
“SiGesTIC’2017”, Hotel Memories, Varadero, 26 – 29 Septiembre 2017.
2012 Increased yields from enhanced quality standards for the HEBERTRANS
immunotherapeutic production process in a new facility at CIGB. International
Congress “Biotecnología Habana 2012”.
Demostración de la consistencia del proceso de obtención del IFA de Factor de
Transferencia Humano. International Congress “Cubafarmacia 2012”.
2011 Repurposing of the epidermal growth factor. J. Comm. Biotechnol. 17 (1): 45 – 52.
2009 Performance evaluation of a pilot plant for investigational new drugs. J. Agric.
Biotechnol. & Ecol. 2 (2): 189-204.
2007 Taking stock of Cuban Biotech. Nature Biotechnology 25 (11): 1215-1216.
2006 Biotechnology in Cuba: 20 years of scientific, social and economic progress. J. Comm.
Biotechnol. 13 (1): 1-11.
2005 On the challenges for developing competitive technologies. Biotecnología Aplicada. 22
(1): 141.
2004 Scale-up of processes to isolate the misstargeted rBm86 protein from Pichia pastoris.
Afr. J. Biotechnol. 3 (11): 599-605.
2004 Production and biochemical characterization of the recombinant Boophilus microplus
Bm95 antigen from Pichia pastoris. Experimental & Applied Acarology 32: 119-128.
2002 Cuban Agro-Biotechnology, business opportunities. International Congress
“Biotecnología Habana 2002”.
1999 Integrated development of recovery for large-scale isolation of the rBm86 protein from
the yeast Pichia pastoris. International Congress “Biotecnología Habana 2002”
1998 Large-scale production of Mucor pusillus rennin from Pichia pastoris. International
Congress “Biotecnología Habana 98”.
Comparison of cell permeabilization and disruption methods for the evaluation of the
rBm86 protein expression in the yeast Pichia pastoris. International Congress
“Biotecnología Habana 98”.
Mechanical disruption of Pichia pastoris yeast to recover the recombinant glycoprotein
Bm86. Enzyme and Microbial Technology 23: 58-63.
1997 Optimization of Pichia pastoris disruption in a bead-mill to recover the recombinant
glycoprotein Bm86. International Congress “Biotecnología Habana 97.”
1995 “Biorreactores”, Havana: Pinos Nuevos, Instituto Cubano del Libro, 1995.

NATIONAL AND INTERNATIONAL CONGRESSES

2013 12th National Workshop for Extention of the Programe Diabetic Foot with Heberprot-P,
Cuba.
2012 International Congress “Biotecnología Habana 2012”, Cuba.
National Congress “Cubafarmacia 2012”, Cuba.
2007 International Congress “Biotecnología Habana 2007”, Cuba.
2003 13th Congress of Clinical Microbiology and Infectious Diseases, United Kingdom.
2002 International Congress “Biotecnología Habana 2002” ”, Cuba.
International Congress of Biochemical Engineering, Mexico.
1999 International Congress “Biotecnología Habana’99” ”, Cuba.
1998 International Congress “Biotecnología Habana’98”, Cuba.
1997 International Congress “Biotecnología Habana’97” ”, Cuba.
AWARDS AND RECOGNITIONS

2014 Institutional Recognition: “Meritorious performance at the Institution during 20 years.”

Signed by: Luis Herrera Martínez, MD, PhD., Marta Ayala Ávila, BSc., PhD.
2011 Institutional Recognition: “High efficiency of the energy sources.”
Institutional Recognition: “Satisfactory results of 9 consecutive external auditory.”
Institutional Recognition: “Satisfactory results of external regulatory inspections from
CECMED (Cuban Regulatory Agency of Medicines).”
Institutional Recognition: “Implementation of the system for reception and control of
fuel.”
2010 Award: Prize of Technology Innovation “High consistency of the manufacturing
processes of Hepatitis B, Tetravalent, and Pentavalent Vaccines” (Ministry of Science
and Thechnology).
Institutional Recognition: “Efficacy of the SCADA system for preventing non
conformities.”
Institutional Recognition: “Satisfactory results of 3 external regulatory auditory from
Chemoy (Russian Pharmaceutical Company).”
Institutional Recognition: “Sanitary License of Pharmaceutical Operations (SLPhO) for
Transfer Factor.”
2009 Institutional Recognition: “Results of energy optimization.”
Institutional Recognition: “Implementation of the manufacturing process of the PhAI
Transfer Factor in a new facility, increasing of quality standard, SLPhO, and record
productivity.”
Institutional Recognition: “High fiability of critical systems’ maintenance.”
Institutional Recognition: “Satisfactory results of 5 external regulatory auditory from
CECMED.”
2008 Institutional Recognition: “Satisfactory results of microbial control of manufacturing
facilities.”
2006 Institutional Recognition: “Approval of 27 due diligences, and new drug applications
(NDA) with significance for foreign commercial operations.”
2005 Institutional Recognition: “License of Pharmaceutical Operations (LPhO) for Hepatitis
B vaccine.”
Institutional Recognition: “Validation of sterilization and clean room operations in
manufacturing facilities.”
Institutional Recognition: “Increase of fiability of critical systems.”
2002 Institutional Recognition: “R&D license agreement of a peptide for treatment of
genitourinary lesions and tumors associated to the Human Papiloma Virus (HPV).”
Institutional Recognition: “Design and implementation of a website for business
development.”
International Association of Web Masters and Designers (IAWMD): “Golden Web
Award 2002-2003.”
Institutional Recognition: “Increase of recovery in the production of the protein
rBm86.”
Institutional Recognition: “Approval for commercialization of the vaccine GAVAC.”
Institutional Recognition: “Impact of the vaccine GAVAC in Cuba.”
Institutional Recognition: “Technology transfer of the vaccine GAVAC.”
2001 Institutional Recognition: “CIGB’s Business Plan 2001 - 2005.”
Institutional Recognition: “Increase of productivity and cost reduction of the vaccine
GAVAC.”
2000 Institutional Recognition: “Production of an antigen for the control of the cattle tick
Boophilus microplus.”
 II CENTRO DE INGENIERIA
GENETICA

LOGRO INSTITUCIONAL 2007

Como reconoci~nientoal trabajo realizado por: Autores- Jorge L. Vega, Manuel E. Montane, Iriac
Bisquet, Tania de la Cruz, Orlando Civico, Jose A. Acosta, Dienys Espinosa, Arlin Garcia.

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Dr. ~ d z ~ e r r e Martinez
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F i d e l Castro
mn"- & '~irectorCIGB
 ENTRO DE INGENIER~AGEN

CERTIFI
A: J o s i Angel Acosta Buxado

Por haber cursado y aprobado: Recalificacion Gestion de Riesgo.

Con una Evaluation de: 4 puntos
Impartido el dia 1 d e diciembre de 2006
Con un total 2 horas clases

Dado en Ciudad de L a Habana, a 10s 23 dias del mes de febrero del2007

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r i a m l e n a Cisneros Palacio .% bm Sonia hegrin Martinez

L X esor Principal \t&3 CIGB
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 ICIDCA

El lnstituto Cubano
. de lnvestigaciones de 10s Derivados de la CaAa de Azllcar
otorga el presente

CERTIFICADO
A. Jose Angel Acosta Buxado

Por haber participado en el curso de Postgrado

lntroduccion al Analisis de Procesos

Celebrado en el period0 del 21 de enero a16 de marzo del2009

Dado en Ciudad de La Habana el 6 e manodel *Oo9

 CENTRO NACIONAL
DE INVESTIGACIONES CIENTIFICAS
Ave 25 y 158, Cubanachn, Playa. Apartado 6414., TEL. 208-6009, FAX 208-0497
CWDAD DE LA HABANA

CERTIFICO

Que el cro. (a) Jose Anael Acosta Buxado realizo en el

Departamento de Docencia del CNIC el examen de suficiencia en
COMPUTACION, correspondiente al proceso de Categorizacion para
el cargo de Especialista en Tecnologias de Avanzada, obteniendo la
calificacion general de (5) puntos.
Las calificaciones obtenidas en cada contenido fueron:
Windows: (5)
Word: (5)
Excel: (a
Correo: (5)
Redes: (!i
J
Power Point: (5)

Tribunal de Examen:
PRESIDENTE: Tecnologo Primer nivel MSc. Gilberto Tillan
SECRETARIO: DrC. Estrella A~varezVarela.
MIEMBROS Ing. Jose Seco
McS. Ricardo Ricardo Parellada

Dado en Ciudad de la Habana, a 10s 19 dias del mes de febrero de 2009

J
Presidente del Tribunal Jefa del dpto. de Docencia.
CNlC CNIC.
 CENTRO NACIONAL
DE INVESTIGACIONES CIENTIFICAS
.-\ye 25 y 158. Cubanacln, Playa., TEL. 208-6530
C'II'D:\D DE L-\H.\B.-\S.4

.
Que el cro. (a): Jose Angel Acosta Buxado realizo en el Departamento
Docente del CNlC el examen de ldioma lngles, para Especialista en
Tecnologias de Avanzada I Nivel el d i a . w d e l mes de febrero del afio
2009, obteniendo la calificacion general de 3 puntos.

Tribunal de Examen
Presidente: Prof. Aux.Marta Cristofol Corominas
Secretario: Prof. Aux. Jesus Nufiez Romav
Miembros: Prof. Asist. Senia Bermudez Velazquez

Dado en Ciudad de la Habana, a 10s 19 dias del mes de febrero del 2009. Aiio del 50 Aniversario
del Triunfo de la Revolucion

P *- ..

Presidente del ~ r i b u n a i
CNlC Jefa del Dpto. Docente
CNlC
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