II.

PATHOPHYSIOLOGY (Schematic Diagram)

Risk Factors Predisposing Factors

Western Heritage Unprotected sex
History of Ectopic Bacterial Infections:
Pregnancy Chlamydiae
History of Tubal trachomotis
Occlusion Nisseria
Age < 25 years old gonorrheae

Entry of pathogens to the

female reproductive tract

Chlamydiae reproduce N. gonorrheae attaches to the

throught binary fission surface of urogenital epithelial cells

Reproduction and
Replication

Attachment of pathogens Coinfection of Chlamydieae

in the epithelial cells and N. gonorrheae

Pili prevents Depressed neutrophil

WBC invasion phagocytosis

Acute Inflammatory LOW GRADE

Process FEVER

Reproductive tract becomes

hyperemic and edematous
 ABNORMAL VAGINAL Purulent exudate
DISCHARGES WITH FOUL ODOR production

Excessive and Obstruction of

trapped exudates Fallopian tube

Swelling of the Pelvic Inflammatory

fallopian tube Disease

LOWER QUADRANT
ABDOMINAL PAIN
LOW GRADE ABDOMINAL FOUL VAGINAL
FEVER PAIN DISCHARGES

Untreated Pelvic
Inflammatory Disease

Spreading of
infected cells

PERSISTENT ABNORMAL
ABDOMINAL PAIN VAGINAL BLEEDING