Radioactive tracer used to localize phaeochromocytomas is ?

Harrison�s 18th Ed. 2963

A. 131I- or 123I-metaiodobenzylguanidine (MIBG)
B. 111In-somatostatin analogues
C. 18F-dopa (or dopamine)
D. All of the above

Which of the following provides better diagnostic sensitivity in

the diagnosis of phaeochromocytomas ?
Lancet 2005;366:665-675
A. CT
B. MRI
C. 18F-fluorodopamine PET
D. 131I-MIBG

Which of the following is an ?-adrenoceptor blocker ?

Lancet 2005;366:665-675
A. Prazosin
B. Doxazosin
C. Urapidil
D. All of the above

In pheochromocytoma, phenoxybenzamine should be

administered for at least how many days prior to surgery ?
A. 2 to 5 days
B. 5 to 10 days
C. 10 to 14 days
D. 14 to 21 days

Malignant phaeochromocytoma can metastasize to ?

Lancet 2005;366:665-675, Harrison�s 18th Ed. 2964
A. Bones
B. Lungs
C. Liver
D. All of the above

Which of the following features of phaeochromocytoma have a

higher risk for malignant disease ?
Lancet 2005;366:665-675
A. Large size (5 cm)
B. Paragangliomas with SDHB mutations
C. Increased plasma/urinary dopamine and dopa
D. All of the above

Sipple�s syndrome is also called ?

Harrison�s 16th Ed. 2149
A. MEN type 1A
B. MEN type 1B
C. MEN type 2A
D. MEN type 2B

Multiple endocrine neoplasia type 2A is characterized by ?

Harrison�s 18th Ed. 2964
A. Medullary thyroid carcinoma (MTC)
B. Pheochromocytoma
C. Hyperparathyroidism
D. All of the above

Multiple endocrine neoplasia type 2B is characterized by ?

Harrison�s 18th Ed. 2964
A. Medullary thyroid carcinoma (MTC)
B. Pheochromocytoma
C. Multiple mucosal neuromas
D. All of the above

Which of the following is not a feature of pheochromocytomas in

MEN 2 ?
Harrison�s 18th Ed. 2964
A. Benign
B. Located in adrenals
C. MTC may be symptomatic before pheochromocytoma
D. Bilateral

Abdominal extraadrenal pheochromocytoma are located in

association with ?
Harrison�s 16th Ed. 2148
A. Celiac ganglia
B. Superior mesenteric ganglia
C. Inferior mesenteric ganglia
D. All of the above

Hereditary phaeochromocytomas occur in ?

Harrison�s 16th Ed. 2148
A. MEN type 2
B. Von Hippel-Lindau syndrome
C. Neurofibromatosis type 1
D. All of the above

Which of the following is false about pheochromocytoma ?

Harrison�s 16th Ed. 2148
A. Solitary lesions are right sided
B. Highly vascular
C. Tumors are not innervated
D. None of the above
596 Features that suggest familial pheochromocytoma include ?
Harrison�s 16th Ed. 2149
A. Bilaterality
B. Multicentricity
C. Age of onset < 30 years
D. All of the above

597 Which of the following is a hypotensive peptide ?

Harrison�s 16th Ed. 2149
A. Endothelin
B. Adrenomedullin
C. Erythropoietin
D. Neuropeptide Y

598 In pheochromocytoma, elevated level of amylase is due to ?

Harrison�s 16th Ed. 2150
A. Damaged pulmonary endothelium
B. Associated pancreatitis
C. Sialolithiasis
D. All of the above
599 To assess adequacy of collected urine sample, which of the
following should also be determined ?
Harrison�s 16th Ed. 2150
A. Urea
B. Creatinine
C. Sodium
D. Potassium

600 Which of the following may cause hypertension & increased

excretion of catecholamines/catecholamine metabolites ?
Harrison�s 16th Ed. 2151
A. Posterior fossa tumors
B. Subarachnoid hemorrhage
C. Diencephalic or autonomic epilepsy
D. All of the above