Version12015

Moduleguide
InternationalMasterProgram
CardiovascularScience
UniversityofGttingen


Part1
Theoreticalmodules

Synopsis
TheMasterprogramCardiovascularSciencecontainsfourtheoretical
modules (M.CVS.101; M.CVS.102, M.CVS.201, M.CVS.301) with a
consecutive curriculum covering basic knowledge on the organ and
molecular level of the cardiovascular system, on cardiovascular
diseases and therapies as well as on modern aspects of
cardiovascularscience.Inaddition,thiscurriculumisaccompaniedby
themoduleM.CVS.004whichincludesthetrainingandattendanceof
presentationsofrecenttopicsincardiovascularresearch.

M.CVS.101:CardiovascularBasicsI
M.CVS.101:CardiovascularBasicsII
M.CVS.001:LabrotationI

M.CVS.201:Cardiovasculardiseasesandtherapies
M.CVS.002:LabrotationII

M.CVS.301:Cardiovascularresearchinacademiaandindustry
M.CVS.003:LabrotationIII

M.CVS.004:ModerntopicsinCVSandclinicalresearch

GeorgAugustUniversityGttingen 9ECTS
ModuleM.CVS.101:CardiovascularbasicsI 7SWS

Learningoutcomes Totalhours
Students who have successfully finished this module have an advanced Contacthours
knowledgeof: 98h
1.) The anatomy of the heart, the vasculature, the lung, the kidney, the Selfstudy
nervous system of humans, rodents and widely used experimental animals 172h
(e.g.zebrafish)
2.)Theembryonicdevelopmentingeneralandofthecardiovascularsystem
3.) The physiology of the heart, the circulation, the lung, the kidney, the
autonomousnervoussystemincludinge.g.detailedknowledgeonthecontrol
of cardiac contractility and function, the short and long term control of the
bloodpressure,importanthemodynamiclaws
4.)Thehormonalcontrolofthecardiovascularsysteme.g.bycatecholamines,
theRAAS,natriureticpeptides,sexhormones

Courses 5SWS
1.CardiovascularbasicsI(Lectures,70h)
Content
Cardiovascularanatomy
Cardiovascularembryology
Cardiovascularphysiology
Cardiovascularnervoussystem
Cardiovascularendocrinology

2.CardiovascularbasicsI(Practicalcourse,28h) 2SWS
Content
Thecardiovascularanatomy
Histologycourseofcardiovasculartissues
CardiovascularPhysiology

Examination:
Writtenexam(180min)aboutthedevelopment,physiologyandanatomyof
theheartandthecardiovascularsystemanditshormonalandnervous
regulation.

Entryrequirement Recommendedprerequisites
None None
Language Modulecoordinator
English Dr.LauraZelarayanBehrend
Frequency Duration
Eachwintersemester 7weeks
Repeatability Recommendedsemesterofstudy
twice 1
Maximalnumberofstudents
25

Additionalnotesandregulations:

Teachingcapacityprovidedby:
MedVK:54hlecture,28hpracticalwork;MedKT:16hlecture;Med.K:


GeorgAugustUniversityGttingen 9ECTS
ModuleM.CVS.102:CardiovascularbasicsII 7SWS

Learningoutcomes Totalhours
Students who have successfully finished this module have an advanced Contacthours
knowledgeof: 98h
1.) The detailed structure of eukaryotic cells and especially of cardiovascular Selfstudy
cells including cardiomyocytes, smooth muscle cells, endothelial cells, 172h
fibroblasts,epithelialcells,stemcells
2.) Important cellular processes e.g. proliferation, migration, contraction,
apoptosis,necrosis
3.) Intracellular mechanisms e.g. transcription, translation, PTM,
exo/endocytosis,proteindegradation
4.)Theregulationofactionpotentials,ionfluxes,transporters
5.)Thermodynamics,hydrodynamics,biomechanics
6.) The cellular metabolism including glucose, fatty acid and amino acid
metabolism
7.)Proteincompositionandstructures
8.)ThegeneticandepigeneticcontrolofproteinexpressionincludingtheDNA
architecture, replication, transcription, DNA modifications, histon
modifications
9.) Import concepts of signal transduction including membrane and
intracellularreceptordependentsignalinginvolvinge.g.kinasesphosphatases,
G proteins, second messengers, transcription factors, oxygen and redox
signaling

Courses 6SWS
1.CardiovascularbasicsII(Lectures,84h)
Content
Cardiovascularcellbiology
Cardiovascularbiophysics
Cardiovascularbiochemistry
Cardiovascular(epi)genetic
Cardiovascularsignaltransduction

Examination
Writtenexam(180min)aboutthefunctionofdifferentsourcesofcelltypes,
importantbiochemicalandbiophysicalcellularprocesses,signaltransduction
processesintheheartandbasicsof(epi)genetics
2.CardiovascularbasicsII(Seminar,14h) 1SWS
Content
Presentationofrecentpublicationsfromthecardiovascularfield.
Examination
Seminarpresentation(oral,15min):ShortPowerPointpresentationabouta
giventopic,includingmax.5minutesdiscussion

Entryrequirement Recommendedprerequisites
None PassedexaminationinmoduleM.CVS.101
Language Modulecoordinator
English Dr.KatrinStreckfuBmeke
Frequency Duration
Eachwintersemester 7weeks
Repeatability Recommendedsemesterofstudy
Twice 1
Maximalnumberofstudents
25

Additionalnotesandregulations:

Teachingcapacityprovidedby:
MedVK:20hlecture,4hseminar;MedKT:30hlecture,6hseminar;Med.K:34h,4hseminar

GeorgAugustUniversittGttingen 9ECTS
ModuleM.CVS.201:Cardiovasculardiseasesandtherapies 7SWS

Learningoutcomes Totalhours
Studentswhohavesuccessfullyfinishedthismodulehaveanadvanced Contacthours
knowledgeof: 98h
1.)Etiologyandpathophysiology,signsandsymptoms,diagnosis, Selfstudy
classifications,management,prognosisofimportantcardiovasculardiseases 172h
includinge.g.coronaryarterydisease,loaddependentheartdiseases,
cardiomyopathies,myocarditis,pulmonaryheartdiseases(PAHandCOPD),
arrhythmiaandtheiroutcomese.g.myocardialinfarction,stroke,leftandright
heartfailure
2.)Riskfactorsforheartdiseasesincludingdiabetes,hypertension,metabolic
syndrome
3.)Importantmolecularcausesforcardiovasculardiseasesincludinginvolved
genemutationsanddiseasedependentmolecularchanges
4.)Importanttechnologiesincardiovascularimagingincluding
echocardiography,computedtomography,magneticresonanceimaging
5.)Treatmentstrategiesandbasicpharmacologicalprinciplesincluding
pharmacodynamics,pharmacokinetics,interferencewiththecatecholamine,
acetylcholineandRAAsystems,diuretics,antiarrhythmicdrugs,vasodilators,
lipidloweringdrugs,antithromboticdrugs,antidiabeticdrugs
6.)Modern(experimental)therapeuticapproachesincludinggenetherapy,
cellbasedtherapy,tissueregeneration
7.)Interventionaltherapiesincludingcoronarycatheterization,stent
implantation
8.)Cardiacsurgeriesofacquiredheartdiseases,ofthevasculatureand
congenitalheartdefectsincludingheartandvalvetransplantation,bypass
surgery.

Courses 6SWS
1.Cardiovasculardiseasesandtherapies(Lecture,84h)
Content
Clinicalandmolecularaspectsofcardiovasculardiseasesinadultsand
children
Cardiovascularimaging
Interventionaltherapies
Cardiovascularsurgery
Cardiovascularpharmacology

2.Cardiovasculardiseasesandtherapies(Practicalcourse,14h) 1SWS
Content
ECGreading
Casestudies

Examination
Writtenexam(180min)thediagnosisofcardiovasculardiseasesviaimaging
andtheirpharmacologicalandinterventionaltherapies,clinicalaspectsof
cardiovasculardiseasesinadultsandchildren

Entryrequirement Recommendedprerequisites
None PassedexaminationinmoduleM.CVS.101and
 M.CVS.102
Language Modulecoordinator
English Prof.SusanneLutz
Frequency Duration
Eachsummersemester 7weeks
Repeatability Recommendedsemesterofstudy
Twice 2
Maximalnumberofstudents
25

Additionalnotesandregulations:

Teachingcapacityprovidedby:
MedVK:;MedKT:28hlecture;Med.K:56hlecture,14hpracticalwork


GeorgAugustUniversittGttingen 9ECTS
ModuleM.CVS.301:Cardiovascularresearchinacademiaand 7SWS
industry

Learningoutcomes Totalhours
Studentswhohavesuccessfullyfinishedthismodulehaveanadvanced Contacthours
knowledgeof: 98h
1.)Specifiedtopicsofcurrentcardiovascularresearch Selfstudy
2.)Stateoftheartmethodologyincardiovascularresearchincludinge.g. 172h
animalmodels,imagingtechniques,highthroughputtechnologies,stemcell
basedresearch,tissueengineering,systembiology
3.)Biostatistics
4.)Researchstandardsinindustry
5.)Thedesignandmanagementofclinicaltrials

Courses 6SWS
1.Cardiovascularresearchinacademiaandindustry(Lecture,84h)
Content
ScientificAspectsofcardiovasculardiseases
Stateoftheartresearchmethods
Biostatistics
Designandmanagementofclinicaltrials
Insightsinresearchinindustry

Examination
Writtenexam(180min)basicsofbiostatisticalmethodsandthemanagement
anddesignofclinicaltrials,differentstateoftheartmethodsandhigh
throughputtechnologiesincardiovascularresearch
2.Cardiovascularresearchinacademiaandindustry(Seminar,14h) 1SWS
Content
Presentationofrecentpublicationsfromthecardiovascularfield.
Examination
Seminarpresentation(oral,15min):ShortPowerPointpresentationabouta
giventopic,includingmax.5minutesdiscussion

Entryrequirement Recommendedprerequisites
None PassedexaminationsinmodulesM.CVS.101,
M.CVS.102andM.CVS.201
Language Modulecoordinator
English Prof.ThomasMeyer
Frequency Duration
Eachwintersemester 7weeks
Repeatability Recommendedsemesterofstudy
Twice 3
Maximalnumberofstudents
25

Additionalnotesandregulations:
Teachingcapacityprovidedby:
MedVK:10hlecture;MedKT:32hlecture,10hseminar;Med.K:42hlecture,4hseminar

GeorgAugustUniversittGttingen 6ECTS
ModuleM.CVS.004:ModerntopicsinCVSandclinicalresearch 5SWS

Learningoutcomes Totalhours
Thiscourseintegratesthetrainingandattendanceofthepresentationsof Contacthours
recentpublicationsinthecardiovascularfield.Studentswhosuccessfully 70h
finishedthismodulehavelearnttopresentandcriticallydiscussscientific Selfstudy
topics.Inaddition,thestudentswilllearntodesignfollowupresearchprojects 110h
tothepresentedtopics.

Course(Seminar) 5SWS
Attendanceofscientificpresentations
Activepresentationofrecentpublicationsofthefield
Designofapotentialresearchproject

Examination
Portfolio(containssummariesofthepresentedresearchtopicswitha
maximumof1pagepertopic).
Examinationrequirements
Seminarpresentation(oral,30min):ShortPowerPointpresentationabouta
givenresearchpublication.Presentationshouldcontaininformationaboutthe
scientificbackground,usedmethodsandconcludingdatadiscussion

Entryrequirement Recommendedprerequisites
None None
Language Modulecoordinator
English Prof.WolframZimmermann/N.N.
Frequency Duration
Eachsemester 3Semester
Repeatability Recommendedsemesterofstudy
Twice 13
Maximalnumberofstudents
25

Additionalnotesandregulations:

Teachingcapacityprovidedby:
MedVK:;MedKT:70hseminar;Med.K:

Part2
Practicalmodules

Synopsis
TheMasterprogramCardiovascularSciencecontainsthreepractical
modules(M.CVS.001;M.CVS.002,M.CVS.003)eachwithadurationof
8weeksandafinalmodule(M.CVS.401)inwhichthemasterthesisis
performedoveraperiodof6month.

M.CVS.101:CardiovascularBasicsI
M.CVS.101:CardiovascularBasicsII
M.CVS.001:LabrotationI

M.CVS.201:Cardiovasculardiseasesandtherapies
M.CVS.002:LabrotationII

M.CVS.301:Cardiovascularresearchinacademiaandindustry
M.CVS.003:LabrotationIII

M.CVS.004:ModerntopicsinCVSandclinicalresearch

MasterThesis


GeorgAugustUniversittGttingen 12ECTS
ModuleM.CVS.001:LabrotationI 18SWS

Learningoutcomes Totalhours
Thepracticalworkwillbeperformedinagroupwithanexpertisein Contacthours
cardiovascularresearchunderdirectonetoonesupervision.Byworkingina 252h
researchprojectthestudentswilllearn Selfstudy
1.)Answeringscientificquestionswithstateofthearttechniques 108h
2.)Analyzingtheobtaineddatacritically
3.)Managingtimeandresourcesinascientificproject
4.)Presentinganddiscussingthedatainanappropriatescientificwrittenform
5.)Presentingthedatainanoralpresentation.

Course 17SWS
1.LabrotationI(Practicalcourse,238h)
Examination
Scoringofthepersonalperformance,clarityandcompletenessofthelabbook
andthelabreport(max.20pages).Labreportshouldbebuilduplikea
scientificpublicationcontainingIntroduction,Materials&Methods,Results
andDiscussion.
Course 1SWS
LabrotationexperienceI(Seminar,14h)
Examination
Oralpresentation(30min):PowerPointpresentationabouttheownlab
rotationcontaining:shortinformationabouttheinstitution,topicofthelab
rotation,shortscientificbackground,usedmethodsandconcludingdata
discussion.

Entryrequirement Recommendedprerequisites
None None
Language Modulecoordinator
English Prof.RalfDressel
Frequency Duration
Eachsemester 8weeks
Repeatability Recommendedsemesterofstudy
Once 1
Maximalnumberofstudents
1

GeorgAugustUniversittGttingen 12ECTS
ModuleM.CVS.002:LabrotationII 18SWS

Learningoutcomes Totalhours
Thepracticalworkwillbeperformedinagroupwithanexpertisein Contacthours
cardiovascularresearchunderdirectonetoonesupervision.Byworkingina 252h
researchprojectthestudentswilllearn Selfstudy
1.)Answeringscientificquestionswithstateofthearttechniques 108h
2.)Analyzingtheobtaineddatacritically
3.)Managingtimeandresourcesinascientificproject
4.)Presentinganddiscussingthedatainanappropriatescientificwrittenform
5.)Presentingthedatainanoralpresentation.

Course 17SWS
1.LabrotationII(Practicalcourse,238h)
Examination
Scoringofthepersonalperformance,clarityandcompletenessofthelabbook
andthelabreport(max.20pages).Labreportshouldbebuilduplikea
scientificpublicationcontainingIntroduction,Materials&Methods,Results
andDiscussion.
Course 1SWS
LabrotationexperienceII(Seminar,14h)
Examination
Oralpresentation(30min):PowerPointpresentationabouttheownlab
rotationcontaining:shortinformationabouttheinstitution,topicofthelab
rotation,shortscientificbackground,usedmethodsandconcludingdata
discussion.

Entryrequirement Recommendedprerequisites
None None
Language Modulecoordinator
English Prof.RalfDressel
Frequency Duration
Eachsemester 8weeks
Repeatability Recommendedsemesterofstudy
Once 2
Maximalnumberofstudents
1

GeorgAugustUniversittGttingen 11ECTS
ModuleM.CVS.003:LabrotationIII 17SWS

Learningoutcomes Totalhours
Thepracticalworkwillbeperformedinagroupwithanexpertisein Contacthours
cardiovascularresearchunderdirectonetoonesupervision.Byworkingina 238h
researchprojectthestudentswilllearn Selfstudy
1.)Answeringscientificquestionswithstateofthearttechniques 92h
2.)Analyzingtheobtaineddatacritically
3.)Managingtimeandresourcesinascientificproject
4.)Presentinganddiscussingthedatainanappropriatescientificwrittenform

Course 17SWS
1.LabrotationII(Practicalcourse,238h)
Examination
Scoringofthepersonalperformance,clarityandcompletenessofthelabbook
andthelabreport(max.20pages).Labreportshouldbebuilduplikea
scientificpublicationcontainingIntroduction,Materials&Methods,Results
andDiscussion.

Entryrequirement Recommendedprerequisites
None None
Language Modulecoordinator
English Prof.RalfDressel
Frequency Duration
Eachsemester 8weeks
Repeatability Recommendedsemesterofstudy
Once 3
Maximalnumberofstudents
1

GeorgAugustUniversittGttingen 30ECTS
Masterthesis

Learningoutcomes
Thepracticalworkwillbeperformedinagroupwithanexpertisein
cardiovascularresearchunderdirectonetoonesupervision.Byworkingina
researchprojectthestudentswilllearn1.)Answeringscientificquestionswith
stateofthearttechniques2.)Analyzingtheobtaineddatacritically3.)
Managingtimeandresourcesinascientificproject4.)Presentingand
discussingthedatainanappropriatescientificwrittenform5.)Presentingthe
datainanoralpresentation.

Course
Masterthesis
Examination 30ECTS
TheMasterthesiswillbejudgedbytworeviewersaccordingtocommon
scientificstandardsandrules

Entryrequirement Recommendedprerequisites
67ECTS 90ECTS
PassedtheoreticalmodulesM.CVS.101,
M.CVS.102;M.CVS.201,M.CVS.301
PassedpracticalmodulesM.CVS.001,
M.CVS.002
Language Modulecoordinator
English None
Frequency Duration
Everytime 6months
Repeatability Recommendedsemesterofstudy
Once 4
Maximalnumberofstudents