Notes and Cautions abbreviation list in the appendix), the terms OTC or endorse such uses, procedures, or dosages.
endorse such uses, procedures, or dosages. The
Dosages and Extra-Label Use of Medications
Dosages for the various species for the drugs
listed in this reference come from a variety of sources
and are referenced to their source in the appendix.
While a sincere effort has been made to assure that
the dosages and information included in this book are
accurate and reflect the original sources information,
errors can occur; it is recommended that the reader
refer to the original reference or the approved labeling
information of the product for additional information
and verification of all dosages.
Except for labeled dosages for veterinary-
approved products (for a given species and indication,)
dosages listed in this reference should be considered
extra-label and are not necessarily endorsed by the
manufacturer, the Food and Drug Administration
(FDA) or this author. Veterinarians are responsible as
per the Animal Medical Drug Use Clarification Act
(AMDUCA) for the appropriate use of medications.
The Animal Medicinal Drug Use Clarification Act of
1994 (AMDUCA) allows veterinarians to prescribe
extralabel uses of certain approved animal drugs and
approved human drugs for animals under certain
conditions. Extralabel (or extra-label) use refers to the
use of an approved drug in a manner that is not in
accordance with the approved label directions. The
key constraints of AMDUCA are that any extralabel
use must be by or on the order of a veterinarian within
the context of a veterinarian-client-patient relationship,
must not result in violative residues in food-producing
animals, and the use must be in conformance with the
implementing regulations published at 21 CFR Part
530. A list of drugs specifically prohibited from extra-
label use appears in the Code of Federal Regulations.
For additional information go to the FDA-Center for
Veterinary Medicine Website at:
http://www.fda.gov/cvm/
Abbreviations: OTC & Rx
In addition to the abbreviations used in
writing prescriptions (e.g., tid, q8h, etc.see the
Rx are found in parentheses after a listed dosage form.
If Rx, the drug is considered to be a prescription or
legend product, and requires a prescription. OTC
denotes that the item is available over-the-counter
and does not legally require a prescription for
purchase.
Trade and Proprietary Names
The notation used to signify trade names or
proprietary names is an italicized, capitalized name
followed by a (e.g., Amoxi-Tabs). This notation
may not accurately represent the drugs official
registered copyright, trademark, or licensed status
(e.g., , etc.). For clarity, no use of or italics are
used in the index.
Drug Interactions
Drug interaction identification and evaluation
is in its infancy in veterinary medicine, as relatively
little specific information is known on the subject for
the variety of species treated. While drug interactions
can be clinically significant and potentially life-
threatening in veterinary patients, most of the
interactions listed in the monographs are derived from
human medicine (which is only slightly more
informed than veterinary medicine on this topic) and
are often included primarily to serve as cautions to the
prescriber to be alert for unforeseen outcomes, or to
enhance monitoring associated with the drug therapy.
Additionally, it is likely there are potentially many
other clinically significant interactions between drugs
that are not listed; prescribers are reminded that the
risk for adverse drug interactions occurring increases
with the number of different drugs given to an
individual patient.
Disclaimer
The author/publisher/distributor assume no
responsibility for and make no warranty with respect
to results that may be obtained from the uses,
procedures, or dosages listed, and do not necessarily
author/publisher shall not be liable to any person
whatsoever for any damages, or equivalencies, or by
reason of any misstatement or error, negligent or
otherwise obtained in this work. Should the purchaser
not wish to be bound by the above, he/she may return
the reference to the distributor for a full refund.
How To Search Within This Reference
As e-books on digital devices ostensibly can
be searched rapidly for a given term, a traditional
index is not required. Enter the desired term in the
search box for your particular reader/device. Usually
this is the most rapid method to find the search term
desired. However, due to the large size of this
reference, some digital devices may take significant
time to do a search through the entire reference. If so,
alternatively:
If you know the generic name for the drug,
browse through the listings in the Table of
Contents and select the appropriate monograph
or section desired;
If you know the trade name (e.g., Anipryl) or a
synonym (e.g., Ldeprenyl) for a systemic drug,
but cannot recall the generic name (e.g.,
selegiline), browse through the listings in the
Index of Systemic Drug Common Trade Names
& Synonyms and select the trade name desired to
go directly to the monograph for that trade name
or synonym. Another link to this section is found
at the end of the Table of Contents.
If you want to see a listing of Systemic Drugs
Sorted by Therapeutic Class or Major Indication
(e.g., all the ACE Inhibitors that have doses listed
for a given species class); go to that section and
browse and select as above. Another link to this
section is found near the end of the Table of
Contents.