Shift+Ctrl+N

Create New layer

Ctrl+New Layer icon

Create new layer behind
selected layer

Alt+Delete (foreground)
Fill a layer or Ctrl+Delete (background)

Ctrl+Alt+Shift+E
Flatten layers

Ctrl+Shift+E
Merge visible layers

Ctrl+Alt+E
Stamp down selected layers

Ctrl+J
New layer via copy

Ctrl+Shift+J
New layer via cut

Ctrl+Shift+]
Bring layer to top of stack

Ctrl+Shift+[
Send layer to bottom of
stack

Ctrl+]
Bring layer forward

Ctrl+[
Send layer back

Shift+Ctrl+C
Copy multiple layers
 Ctrl+Shift+D
Reselect

Ctrl+Shift+I
Invert selection

Ctrl+Alt+A
Select all layers

Alt+,
Select bottom layer

Alt+.
Select top layer

Alt+drag
Deselect from the selection
area

Shift+Alt+drag
Deselect all but the
intersected area

Ctrl+D
Deselect the entire image

Ctrl+T, then Ctrl+0

Find the sizing handles

Spacebar+Marquee tool
Move a selection

Ctrl+3 (red), 4 (green), 5 (blue)

Select individual channels

Alt+Brush tool
Select a colour from an
image

]/[
Increase/decrease brush size
 Shift+F5
Fill

}/{
Increase/decrease brush
hardness

,/.
Previous/next brush

</>
First/last brush

Shift+Alt+P
Toggle airbrush option

Ctrl+Shift+Alt+S
Save for web & devices

Ctrl+Shift+W
Close and go to Bridge

Ctrl+L
Levels

Ctrl+T
Free Transform

Ctrl+M
Curves

Ctrl+B
Colour Balance

Ctrl+U
Hue/Saturation

Ctrl+Shift+U
Desaturate

Auto Tone
Quick image fixes Shift+Ctrl+L
 Auto Contrast
Alt+Shift+Ctrl+L
Auto Color
Shift+Ctrl+B
Shift+Ctrl+R
Lens correction

Opt+Shift+Ctrl+A
Adaptive Wide Angle

Shift+Ctrl+A
Camera Raw Filter

Ctrl+Shift+Alt+C
Content Aware Scale

Shift+J
Content-Aware Move

Ctrl+Alt+G
Create clipping mask

Shift++ or -
Blending modes

Shift+Ctrl+Alt+B
Black and white dialog box

Ctrl+Alt+i
Change image size

Within Selection
Show/Hide Polygons Alt+Ctrl+X

Reveal All
Opt+Shift+Ctrl+X
Alt+Shift+Ctrl+R
Render

Ctrl+Alt+0
View actual pixels
 Ctrl+0
Fit on screen

Ctrl++
Zoom in

Ctrl+-
Zoom out

Ctrl+Shift+>/<
Increase/decrease size of
selected text by 2pts

Ctrl+Alt+Shift+>/<
Increase/decrease size of
selected text by 10pts

Alt+right/left arrow
Increase/decrease kerning or
tracking

Ctrl+Shift+L/C/R
Align text left/center/right

Ctrl+H
Show/Hide selection on
selected type