New question for MoH prometric Exam

February2015

Eman Mohamed Nasr

: What about binding of drugs is false

A. Affect on plasma and tissue

B. decrease elimination half life
C. Reversible
D. Have limited capacity
E. Attach with weak bond

which of the following is drug dependance-2

a-propanol
b-amphetamine
c-reserpine
d-acetohexamide
dopamine is-3
a-cns stimulant
b- gastric secretion
gastric secretion
to convert solid to fine powder-4
-a-levigationb
b-desintegration
not for heparin-5
a-lyse clot thrombin did
b-affect on factor v111
-c
-d
24 22 10

drug x 0.05%
water ad 250
calculate gm of drug

Maha Sorror

1-antiarrythmic class2.
a-propranolol. b-procainamide. c-lidocaine

2-alkylating anticancer
a-cyclophosphamide. b-cisplatin
3-chlorothiazide SE
a-hyper kalmia. b-hypo kalmia. c-hyperuricmia

4-no side effect of reserpine

a-weight loss. b-Parkinsonism

5-all increase first pass metabolism Xpt

a-bio transformation. b-PKa. c-bio transformation capacity. D-a,c

6-how amount water add to 250 of1:500 to prepare 1:2000 of solution

a-2L. b-4L
C1v1=c2v2

7-action of salbutamol b2agonist

8-cause of traveller diarrhoea and drug
e.coli ttt ciprofloxacin

9-10g. of sub x. Density 1.75 calculate volume?

Sp.gr=wt/vol
Vol=10/1.75=5.71
10-
11-acid base equation;bronsted equation

Emy Ali

volume of distribution affected by except 1

A partition coefficient
B bloob flow to tissue
C ph
D dissolution from dosage form
E b,d

drug used to supply o2 shortly after acute myocardial infraction 2

A aspirin
B fibrinolytic
C morphine
preservative not efficient 3
A use another broad spectrum one
B sterlize product
C use to or more to give synergistic effect
verapamil as class4 antiarrhthmic 4
A supress phase 4 depolarization
B block entry in phase 2

antihyperthyroidism cause agranulocytosis 5
A propylthiouracil
 pharmacikienitic usually 6
A first
B zero
pt with slight increase in ldl 7
A diet control of fat
B exercise
C increase diet fiber
D start therapy
E a,b,c
prephenazine promethazine 8
A used in nausea vomiting
ACEI characterized by except 9
Make sympathetic reflex
coal tar used in psoriasis 10
about diazepam all false except 11
A long duration action
B iv as drug of choice for status epiliptcus

all alkylating except cisplatin 12

in digoxin toxicity which true 13
A monitor ECG
B monitor k,Mg and adjust if needed
C no antidote
amantadine action 14
Increase dopamine release
epinephrine all correct except 15
Oral active
naturally occuring water for external preparation 16
solution which is true 17
Homogenous preparation
' denisty
' ppm
' adeq petrolium
cc30 1:1000
how much gm in 10ml %0.2

Rehab Abdelnaby

Not used as immunosupressed in organ transplantation)1 .

A.prednisoson
B.cyclosporin
C.tacrolimus
D.carmustine
E.mucophenolate
 cn stimulant amphetamin caffien dextemethorphen nicotine

diazepam)2

A. Has long duraton of action

B. Used i.v. for status epilepticus

phase 4)3

A.rest membrane potential predominate k potential

B. Rapid depolarization due to Na influx

propenicid increase penicllin by altering)4

A. Renal tubular reabsorption

B.renal tubular secreation

not occur with loop diuretic)5

A.hypertension
Hypernatremia

false about reserpine)6

A. Inhibit dopa decarboxylase

B.bradycardia

Hala Abdallah

: : What about binding of drugs is false

A. Affect on plasma and tissue

B. decrease elimination half life and decrease side effects
C. Reversible
D. Have limited capacity
E. Attach with weak bond

: : Pharmacological property of class 2 antiarrhythmic drug is1

prolong action potential-1

Slow inward calcium .2
Slow action potential by blocking na channels .3
Decrease tissue repolarization .4
Decrease sympathetic activity by blocking b adrenergic receptors .5
Zeinab Rashad

1which not consequences with change protien binding

A decrease elmination half life
B increase elmination half life
C increase partion coefficient
D decrease side effect

2phase3
1depolrization dueto efflux of k
2rapid repolrization due to efflux of k
3rapid depolrization due to na
4resting membrane potential due to potential of k

3not cause decrease in lipoprotien

A nicotinamide
B cholystramine
C pilicol
D dextrothyroxine

4allopurinol
A anti inflammatory
B Uricoseric
C increase reabsorption of uric acid

5pharmakinetic rate constant usually

A frist order
B zero
C mix
D a.b

6which cause red urin

Phenazopyridin
Isoniazid
Nitro furantoin
Sulphmethoxazole
Terbutalin

7which used wih hydaralazine

A betablocker to ttt reflex tachycardia and diuretic to ttt na water retention

8which exaggerated blood glucose

A Hydrochlorothiazid

9gemfibrazol
Decrease hdl
Decrease lipoprotien lipase
Decrease lipoprotien production

10verapamil increase conc of which drug

Digoxin

11which is not antiviral

A interferon
B squinavir
C ganciclovir
D cyclosporin

12Mode of action of amantadine

Inhibit protien synthesis
Increase release of dopamine presyneptic

13Cyproheptadine
Anti depressant
Anti psychotic
Antihistaminic

Raghad Ammar

:Dont decrease lipoprotein concentration..1

Probacol
Dextrothyroxine
Gemfibrozil
Cholesteramin
Nicotinamid

:longest lag time ..2

Sustained release tablets

Enteric coated
Sugarcoated
capsules

:isoproterenol..3

Alpha and beta agonist

Beta agonist

:verapamil..4
- Suppress phase 4 depolarization
- Deceease inward current carried by phase 2 so decrease polarization and slow conduction in tissues

:dose dependant pharmacokinetics..5

Phenytoin
Carbamazepine
Lithium

:not alpha2 selective agonist..6

Clonidinealpha
methyl norepinephrine
Guanafence
Guanithidine

:not treated by diltiazem..7

Hypertension
angina
Migraine
paroxysmal supraventricular tachycardia
Partial heart block ventricular arrhythmia

:drugs different in active ingredient and have the same effect 2..8
Bioequivalnt
Bioavailable
Pharmaceutical equivalent
Pharmaceutical alternative

-1: phase 4 ccb-1

supress phase 4 depolarization1
dec inward current carried by ca so dec depolarization and slow conduction in tissue -2

1 tablet b.i.d a.c. 2weeks

two tablet after meal twice daily "56 tablet-1
two tablet before meal twice daily " 56 tablet-2
one tablet before meal twice daily " 28 tablet-3
one tablet after meal twice daily 28 tablet-4