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GBS = Guillain Barre Syndrome

MG = Myasthenia Gravis
B = Botulism

GBS MG Botulism

Pathology - antibody formation - autoantibody formation - endotoxin prevent


against peripheral nerves against AChR release of Ach
with subsequent lympho-
cystic infiltration + de-
myelination

Hall Mark Features - ascending paralysis - fatiguable weakness - descending paralysis


- bilateral, symmetrical - ptosis - cranial neuropathy
- motor > sensory - bilateral

Weakness Yes Yes Yes

Reflexes Absent Present Absent

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