Module 1: The Cell, cellular division & other cellular activities, the Gauchers Disease o Amoeboid movement

membrane Kartageners syndrome Mechanism*(my own)

o Organelle involved
OBJ 1: o Structural & biochemical abnormality OBJ 8: Cell death, factors and struc. Changes

Major parts of the cell OBJ 5: Types of intercellular connections/communications Necrobiosis / apoptosis
Composition of the cytoplasm: cytosol & formed elements Necrosis
Cellular macromolecules: building blocks and linkages Cell adhesion molecules (read MAMA GRAYS)
o Chemical composition & function OBJ 9: Relation of membranes chemical composition to its asymmetric
OBJ 2& 3: o Physiologic connections nature & bilayer feature

Nucleus Neural Membrane lipids

o Chemico-structural features & biochemical roles Endocrine o Major lipids & its distribution
o 2 chromatin patterns & staining used Paracrine o Its amphipathic nature
o Sex chromatin & its significance o Structural connections of epithelial cells (elaboration o Lipid bilayer & its importance
o Diff. types of chromosomes based on centromere in UNIT 2: Epithelium) Membrane proteins
location OBJ 6: Cell divisions and assoc. anomalies o Types
Organelles Structural features
o Chemico-structural features & biochemical roles Amitosis Biochemical roles
Mitochondria Mitosis Examples
Golgi app o Requisites before division
ER (RER & SER) o Normal number of chromosomes (somatic & germ OBJ 10: Fluid Mosaic Model
Lysosome cell) Concept of membrane fluidity
Ribosomes o Stages & accompanying structural changes o Features that favor fluidity
Peroxisomes o Common drug affecting mitosis o Role of cholesterol
Inclusion bodies Meiosis o Importance of membrane fluidity to cell function
o Examples & its significance o Normal number of chrom.
Cytoskeletal system (Histo, ana, o Phases, subphases&struc. Changes OBJ 11: Structural components responsible for certain membrane
o Microtubules o Biological importance properties
Its 3 configurations of microtubular Cytogenic anomalies
assembly o Polyploidy, Aneuploidy, Deletion, Non-Disjunction, Selective permeability
Antigenicity
Specialized structure/organelle Translocation
involved Mechanism involved OBJ 12: Diff. types of transport system in cell membrane
Function Example of clinical disorder
Basic protein components & its functions Diffusion
OBJ 7: Cell movement, mechanism & control o Passive vs facilitated
o Intermediate filaments
5 classes Ciliary motion o Factors that influence
Chemical composition o Struc. Component o Mechanism of transport
Cell/tissue they predominated o Human cells that exhibit such movement Active transport
Function Flagellar motion o Primary vs Secondary
Examples of associated DISEASES o Example cells o Factors that influence
o Microfilaments Chemotaxis o Mechanism of transport
2 types of proteins & its functions o Processes & glycoprotein involved o Examplse (Na+ pump)
Movement within cells &cytomorphosis Transport of large particle
OBJ 4: Correlations Movement of large molecules o Endocytosis
 Pinocytosis & phagocytosis
Clathrin-independent vs clathrin-dependent
Endocytosis
Examples
o Exocytosis
Constitutive secretory pathway
Regulated secretory pathway
Examples

OBJ 13: Diff. membrane proteins & examples

Membrane transport proteins function & examples

o Uniport
o Symport
o Anti-port
o Co-transport
o Voltage & Ligand-gated channels
o Aquaporin