Datasheet of AV-412

Detailed information:
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USD250.0/50.0mg;
Price USD400.0/100.0mg
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Product Name AV-412

N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-
Chemical Name
yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide
AV412,AV 412,MP412,MP-412
Synonyms

CAS No. 451492-95-8 Catalog No 112101

Molecular Weight 507.00 N

HN
Molecular Formula C27H28ClFN6O F NH O N

Cl N
Other information N/A N

Items Specifications Results

Appearance Off-white solid Complies

HNMR 400MHz,d6-DMSO Complies

Analysis
HPLC 98.0% Complies

Storage condition Kept under dry and cool condition

The above substance has been tested according to In house Standards, and it
Conclusion
meets requirements.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com
 AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth
factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2),
Description which may result in the inhibition of tumor growth and angiogenesis.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com