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Erowid Extracts

A P s y c h o a c t i v e P l a n t s a n d C h e m i c a l s N e w s l e t t e r

November 2003 Number 5

ooks. Big, heavy, expensive, Our strong belief that this sort of inherited

E r ow i d . o rg i s a m e m b e r-
supported organization working to
B difficult-to-ship dead tree product.
Marvels of the Renaissance and
boat anchors of knowledge.
data needs to be added to the global digital
library inspired our work on the Albert
Hofmann Collection in 2002. And where
provide free, reliable and accurate copyrights allow, or through agreements with
Computers. Alien, annoying, expensive,
information about psychoactive authors and publishers, we continue to work
headache-inducing factory effluent.
plants and chemicals. to collect, digitize and make difficult-to-find
Engines of the Data Age and destroyers of
information more available.
The information on the site is boundaries.
a compilation of the experiences, Digitizing existing materials can improve
Erowid is primarily a digital endeavor.
words, and efforts of hundreds of both the world of computer-accessible
Web publishing allows us to keep costs
individuals including users, parents, information and the usability of printed
low and accuracy high, with no need for
health professionals, doctors, resources. Our current ideal is a physical
expensive reprints every time a piece of
therapists, chemists, researchers, book to read, with a full-text digital copy for
data is corrected or new information added.
teachers, and lawyers. Erowid acts searching and reference. In many ways, a
Internet databases also have the potential for
as a publisher of new information digital index for a physical library is the perfect
truly ubiquitous access, a possibility only
blending of past and present technologies.
as well as a library for the collection hinted at by the invention of the printing
of documents published elsewhere, press, but made real by the current revolution
spanning the spectrum from solid in information and publishing.
peer-reviewed research to creative
Yet as much as we are digital data geeks, Every sentence that I utter
writing and fiction.
we are also bibliophiles. Books and papers
remain the foundation of much of the work
must be understood not as an
we do. We collect printed pages to use affirmation, but as a question.
as resources for writing and answering Niels Bohr
questions, for data checking, to help us keep
up with the current state of knowledge, and
IN THIS ISSUE . . . because they are more pleasant to hold than
a keyboard. In our field, much of the archived
The [Pseudo-] Science knowledge exists only in private collections.
As the worlds knowledge repositories There is the danger that existing libraries will
of the War on Drugs ................ 2 inevitably shift from physical to digital, end up dispersed into the hands of collectors
Erowid 3.0 ............................... 4 we must work to preserve the old while who value them less as data and more as
maximizing the benefit of the new. Although artifacts. With digital tools, it is possible
Conference Reports ................ 5 most of the knowledge gained from the work to preserve and actually enhance these
of past experts exists only in paper form, we
Meme Cultivation ..................... 6 collections without the physical objects
are moving towards a world where the de needing to remain together forever.
Cannabinoids Neuroprotective? 7 facto standard for the state of knowledge
in any given field is based solely on what The love of books and papers should
Looped Reality (N2O Exp.) ...... 8 can be found online. With this change, the not be seen as incompatible with the drive
Myth Debunking ...................... 10 world risks losing existing data and having towards robust digital collections. The digital
to re-create the hard work of previous bibliophile, lost in the dusty stacks with hir
LSD Analysis ........................... 12 generations. portable computer connected wirelessly to
Measured Doses ..................... 18 This problem is especially present in the
the universal network, knows the value of
both. The data geeks of the new millennium
LSD Experience Excerpts ....... 20 field of psychoactive research, where political are the bridge across the technological divide
pressures have compelled public libraries to between the Renaissance and the Information
Escottology .............................. 22 carry only disturbingly juvenile resources Revolution.
Distillation ................................ 23 and caused universities to shy away from
maintaining comprehensive collections. Fire & Earth
The ( Pseudo-
Pseudo-)) Science by Earth Erowid

of the War on Drugs


AND THE RECENT RICAURTE ERROR

M
any Erowid readers are already the science of this field: the lack of a neutral Though neuropharmacological facts dont
aware that there was a major standards or review body for scientific become true or false based on a vote, as data
shake-up in the world of research. stacks up supporting a particular theory its
MDMA neurotoxicity research natural to assume that theory is more likely to
It is common in many fields for the
in September 2003 when George Ricaurte and be true. But if only particular theories are ever
media to jump on new scientific findings
his lab at Johns Hopkins University issued allowed to be studied, the system breaks.
and present them as sensationalist fact. The
a retraction to their controversial article
rush to judgement is certainly not unique There are a few who work to provide
published in the journal Science in October
to the study of recreational psychoactives. some measure of counterpoint to the flood of
2002. The retracted article, which had been
Politics influence everything, including the War on Drugs science. But with their hands
provocatively named Severe Dopaminergic
media, and popular ideas are often out of tied by the current systemwith limited
Neurotoxicity in Primates After a Common
sync with existing scientific understanding. ability to do the research necessary to back
Recreational Dose Regimen of MDMA
In other fields of science, however, there are their theories with datatheir voices are too
(Ecstasy), purported to show that MDMA
two primary pressures which mitigate the easily dismissed by mainstream researchers,
caused severe damage to the dopamine
impact of bad data on public policy and law: physicians, educators and lawmakers.
system and could lead to Parkinsons disease
competing scientific inquiries and neutral
symptoms after a single use. Science, as a result-neutral method for
standards or regulatory bodies.
finding fact, can only function successfully
This paper contradicted previous research
and made claims that were criticized as Competing Scientific Investigations
politically motivated. Papers such as this one In most fields, scientists have the
fuel increasingly draconian legal changes and opportunity to study opposing theories,
Conflicts of Interest
frightful sentencing for drug-related crimes, the ability to conduct experiments and test
all in the name of protecting the children hypotheses, and generally, the freedom Imagine if the FDA not only
from horrors like Parkinsons disease. to question data. Unfortunately, because acted to evaluate whether a phar-
of the War on Drugs, the social, profes- maceutical drug was healthy and
The Retraction sional, and legal pressures are configured useful to the public, but was also
The retraction explained that Ricaurtes to dramatically limit this type of balancing required by its charter to disallow
team had accidentally used methamphet- research into illegal psychoactives. It can and discourage the use of all pain
amine (a known dopamine toxin) instead of be professional suicide for a researcher to medications. They would declare
MDMA in the study, causing deaths, near- come out too vocally against studies that the use of ibuprofen immoral,
deaths, and severe dopamine-system brain find harmful effects, even if the criticism is publish handbooks and review
damage to the primates they experimented technical. Being perceived as pro-drug articles about how ibuprofen
on. Since the retraction, much has been can mean jeopardizing the ability to get causes ulcers and thousands
written about this incident. Commentators grants and inviting increased professional of deaths per year, with no
have highlighted problems ranging from scrutiny. mention of why so many people
use it anyway. Imagine that this
scientific issues about MDMAs effect on Government sources almost never fund body would be the only source
the dopamine system, to the influence of scientific research into alternative theories, of funding for research into this
politics on science, conflicts of interest in the positive effects or therapeutic uses of dangerous type drug.
current system of peer reviewed publishing, proscribed psychoactives, while research
problems with the news-tainment industrys designed to show harm receives hundreds of This Food, Drug, and
treatment of complex scientific matters, and millions of dollars each year. This immense Ibuprofen Abuse Administration
the over-emphasis of negative findings by funding imbalance precludes the competition would have a charter that is
the War on Drugs industry. of ideas required for good science. incompatible with the aims of
producing information society
The Ricaurte Error also brought into Functionally, the scientific world works can rely on.
focus another systemic problem that plagues on a sort of democracy-of-data principle.

2 Erowid Extracts No. 5 / November 2003


when the choices of what and how to study
are not dictated by a foregone conclusion.
into drugs of abuse), but it is also the
body entrusted by the U.S. government to
Erowid Extracts
Number 5, November 2003
Since Ricaurtes article linking Ecstasy use evaluate the evidence, publish papers, and
to Parkinsons disease was published in the testify to Congress about the current state
fall of 2002, there seems to have been an of the science.
increased visibility of the War on Drugs Technical Director Earth Erowid
It is NIDA that sits at the center of the War
machinery and the way it manipulates Head Archivist Fire Erowid
on Drugs science debacle. It has dramatic
ongoing research to match its political
conflicts of interest between its roles as a Crew Spoon
objectives. Many normally silent researchers
neutral standards body, a funder of research mindlace
have reacted with outrage that this article was Psilo
and a governmental hub for the demand
allowed to be published in the first place and Lad
reduction policy objective.
have openly criticized the weight it has been
Art Curator Christopher Barnaby
given in public policy. As Stephen Kish, a brain scan expert,
described at a presentation to NIDA in Report Reviewers Scruff
Unfortunately, as long as a significant Morning Glory Seed
September 2003, NIDA has repeatedly Raoul
portion of research is funded by an agency
overstated the certainty of the data. For Catfish Rivers
with a political agenda, the chance for a
example, under previous director Alan Tacovan
balanced picture to emerge about the use
Leshner, NIDA used brain scans of ques- Copy Edits Urge
and abuse of recreational psychoactives is
tionable validity as part of a huge national Scott O. Moore
very small.
education campaign to show how Figment
dangerous ecstasy was. Dr. Kish said that
Content-Neutral Standards Layout & Design Fire Erowid
NIDA has been effectively misleading both
In many fields there are recognized the public and Congress about how well
organizations that work to create neutral understood the issue of ecstasy-related brain Erowid Extracts is the members newsletter
standards, vet published research, and keep damage is. What is particularly concerning is of Erowid.org. It is published about twice a
track of the status of ongoing scientific that some of the top scientists at NIDA were year. If you are interested in receiving this
debates. well aware of the problems with their official newsletter, visit our membership page:
In the pharmaceutical industry, scientists media campaign, but in the end political and
http://www.erowid.org/donations/
employed by corporations work to show the marketing considerations drove their public
beneficial effects of their potential products description of the science. If you would like to cancel your sub-
scription to Erowid Extracts, please let us
while researchers at universities, independent
Conclusions know. Past issues can be read online.
labs and rival companies test their claims.
Competing scientists challenge theories and The Ricaurte Error stands out as a red http://www.erowid.org/extracts/
argue about the meaning of their findings. flag, a warning that the scientific system in
this field is dangerously flawed if not broken.
The U.S. Food and Drug Administration Erowid
In this case, a bogus finding, inconsistent with P.O. Box 1116
(FDA) also acts as a semi-neutral review
previous research, from a lab known to be Grass Valley, CA 95945
organization for pharmaceutical science. http://www.erowid.org/
biased, was able to influence U.S. law and
The FDA makes decisions about approval info@erowid.org
stop research in other countries. As we are
or removal of pharmaceutical drugs based
immersed further into the post-post-post- 2003 Erowid.org
on its evaluation of current research. If a All rights reserved
modern world where fact and fantasy melt
company disagrees with a finding, they can
in the digital foundries, there is a growing
perform more research or resubmit their
need for neutral scientific expertise isolated Reprints: Those interested in reprinting
data. Although its important to note that articles from this newsletter should contact
from profit motive and political agenda.
there are strong political and economic Erowid by email.
pressures influencing the FDAs decisions, A neutral evaluative body has become
as well as an organizational tendency necessary. Perhaps it can be found outside Advertising: Erowid Extracts does not
towards risk aversion, the vetting process the United States. Or perhaps a private accept advertisements, but if you would
provides a system for the evaluation of data association of scientists in the field can form like to include a flier about a related orga-
nization or event in our mailings, contact
by informed, trained individuals within a a collaborative effort to provide a measure
extracts@erowid.org.
defined structure. of distance from the corrupting influence
of politics. Until then, the field will remain
For illegal or recreationally used
psychoactives, the National Institute on
another pseudoscience.
Drug Abuse (NIDA) is the closest there is For more information see: Know Your Body
to a moderating body. NIDA, a part of the Erowid.org/extracts/n5/ricaurte_retraction.shtml
National Institutes of Health (NIH), has a Know Your Mind
budget of over one billion dollars. It not References
only acts as the funder for nearly all research 1. Ricaurte G, et al. Severe dopaminergic Know Your Substance
neurotoxicity in primates after a common rec-
into recreational drugs (their website claims reational dose regimen of MDMA (ecstasy). Know Your Source
they fund over 85% of the worlds research Science. Sep 27, 2002; 297(5590):2260-
2263.

Erowid Extracts No. 5 / November 2003 3


THE ONGOING PROCESS OF SITE REDESIGN

EROWID 3.0 by Fire & Earth Erowid

A s w e wo r k o n t h e d a y - t o - d a y Interface Changes Content Review System


management of new and existing site content, The current site navigation is more than While the initial release of Erowid 3.0
there are also several large ongoing projects four years old. While it is still functional, it will likely contain only hints of the larger
that we try to keep moving forward. The is obviously outdated. For the past few years, Grass Roots Peer Review system were
largest of these is what we call Erowid 3.0, we have prioritized working on content over working on, were very excited about this
which received a great deal of our time over working on the interface and design, but its developing part of the project. The content
the summer of 2003. The project has been obviously time for a change. review system for Erowid 3.0 uses something
mentioned briefly in past Extracts, but we known in the software development world as
wanted to provide a further outline to keep The most noticeable changes to the
collaborative filtering. Voting and rating
members informed about the progress were interface are new headers and footers that
systems are types of collaborative filtering.
making. use dynamic drop-down menus (ECMA/
Early versions will involve managing the
Javascript) to improve navigation. These
Conceptually, the Erowid 3.0 project per-document comments and corrections
menus provide quicker access to a deeper
is a complete redesign and restructuring of submitted through the new interface and
site structure, meaning less intermediate
the site. It includes front-end changes to providing a system for volunteers and crew
pages to click through when moving from
the look-and-feel, user interface and site to work together to filter and validate these
one area to another. Second, the headers will
organization, as well as back-end changes submissions. Simple error corrections can
include a search field and links to associated
to the data storage and processing systems. be handled by crew, while more complex
topics.
Because Erowid has grown organically over comments could be approved for display at
the past eight years, it is made up of dozens Documents will have more standard- the end of the relevant document.
of different areas which were created at ized authorship, copyright, and publication
Another early piece of the content review
different times, in different formats, with information, hopefully reducing confusion
system is a triage process (described briefly
different looks to meet the needs of the and improving citability. Another major
in Extracts issue 3) for incoming experience
moment. addition is that page footers will provide
reports, images, and article submissions.
direct access to a form for reporting errors
The primary design goals of the Erowid Currently, one of the primary bottlenecks in
and corrections, making it easier to manage
3.0 project are to: our information publishing system is simply
suggested changes to the site.
sorting through and keeping track of the
Update the look of the site. Once the new interface has been status of thousands of waiting submissions.
Improve site interface and navigation implemented and files have been updated The primary function of triage will be to
and take advantage of dynamic browser and regularized, it should be much simpler allow a much larger number of people to help
capabilities. to make interface changes in the future. categorize, critique and approve submissions
before they are ready for publication without
Move to using the HTML 4 standard Two sections of Erowid already have
reducing overall quality or reliability. The
(including CSS) for better maintain- preliminary versions of the new design and
triage process will track submitted items
ability. interface in place. We began beta testing
and comments by triagers, as well as help
the new designs with the smaller and more
Create the necessary underlying us identify valuable volunteers.
manageable Spirit and Freedom Vaults in
structure to make the look-and-feel of July 2003. Other major features of the Erowid
the site user-configurable in the future. content review system include:
Add an error and correction reporting Back End Changes A standardized public interface for
interface to every page. Currently, much of the core content of the viewing a documents review status.
Implement a first draft of the Erowid site exists only as static HTML files, coded
Seeing a list of identified articles that
content review system. and linked to by hand over the last eight years
contradict or support a document.
by the Erowid crew. The Experience Vaults,
Make it easier to add documents. the References Vaults, and Ask Erowid are all Viewing back links (links from other
Integrate existing sections of the site database applications, but they were written documents).
into one coherent system. years apart in different languages, do not
A way to track, browse, and compare the
use the same ontology (category system),
reviews by different crew members.
Although we hope to make Erowid 3.0 and share very little code. This hodgepodge
work well in all browsers, we are targeting means that currently: links between sections Erowid 3.0 will continue to see progress
Mozilla, Internet Explorer, Safari (Mac OS must be made by hand, the systems are amidst other necessary work, but beta testing
X), and Lynx (a text-based web browser) as cumbersome to update, and changes to one parts of the release on the live site has begun
our testing platforms. Erowid 3.0 will not area are not automatically reflected on the and we look forward to feedback about the
support Netscape 4.x. rest of the site. new designs.
4 Erowid Extracts No. 5 / November 2003
Conference Reports

Mind States IV (mindstates.org) ASSA Con (assacon.com)


May 23-25, 2003 July 12-13, 2003

The Mind States IV conference, held at the International Altered States and the Spiritual Awakening was a conscious-
House in Berkeley like two previous Mind States, drew more ness-related conference held by the San Francisco group False
than 500 attendees. Profit. This was the first event of this type that False Profit
has produced. It attracted about 200 attendees, pushing their
The International House is a reasonably good location for
maximum capacity, with minimal advertising (mostly word-of-
conferences; its beautiful main auditorium has a tall vaulted
mouth and mailing lists).
ceiling, good acoustics, and enough peripheral space to
accommodate 500 people. This year the addition of a richly One of the notable advantages to this conference was the low
decorated chill space provided some participants a place to relax entrance fee. Often conferences have high overhead with the
and mingle. The chill space was decorated with visionary art, rental of auditorium space, speakers fees and travel costs. The
including an original Alex Grey painting on loan from a private organizers worked hard to keep costs to a minimum in order to
collection and a life-size mixed-media sculpture depicting the create an event that was affordable to more people while still
spirit of ayahuasca in the form of a wise old woman. providing a full roster of interesting speakers. Conference fees
even included excellent meals (two catered continental breakfasts,
Unfortunately, there are aspects of the layout of the
two lunches and one dinner). Guests could also pay for just one day
International House that are less than ideal. The vendors area,
of talks if their time or budget was limited. Ancillary workshops,
in the hallway outside the auditorium, is quite crowded. The chill
offered by some of the speakers (for additional reasonable fees),
spacethe only place other than the auditorium where guests
allowed more intimate forums.
could hang out in relative comfort and privacyis too small
to accommodate as many people as needed and too separated The venue for ASSA was False Profits warehouse space.
from the main auditorium to be readily accessible. Finally, the It was significantly more informal than the average conference
parking in Berkeley is generally pretty tough, especially this spacethere were couches and cushions on the floor for attendees,
year, as the conference was held on graduation weekend. But who listened to speakers sitting in easy chairs on a raised stage
all in all, the positives of the International House outweigh the in the corner. This provided a very comfy, laid-back atmosphere
negatives. but some participants, especially older guests, found the sofas
uncomfortable for long durations. Presentations were kept
This was arguably the best of the three Berkeley Mind States
impeccably on-time.
conferences, with more speakers, visionary art by more artists, an
auction that benefited related organizations such as Erowid and A large outdoor area was available for those who didnt want
MAPS, Sheldon Norbergs one-man performance of Confessions to be indoors. As this was the only place to be other than the main
of a Dope Dealer, Mark Pesces opera about Terence McKennas room, and was uncovered, its a good thing it didnt rain. As it was,
life, and an interesting collection of attendees. Bob Wallace and Fire got a sunburn from standing out in the sun all weekend.
Mind Books were conspicuously and sadly missed, but books
The topics were well-balanced between empirical and spiritual
from Mind Books inventory were available for purchase.
orientations. Presenters included Stanley Krippner speaking about
Three panel presentationsArtists, Elders, and LSD shamanism; a panel discussion moderated by Erik Davis about
provided the opportunity for more presenters to speak. In some spirituality, technology and altered states; Luis Eduardo Luna
ways this was great, but there were a few speakers on panels, like speaking about the non-shamanic use of ayahuasca; and Charles
Myron Stolaroff, whom we would have loved to hear talk for an Tarts thoughts about enlightenment and spiritual growth.
hour rather than the limited 10 or 15 minutes that was available
Earth and Fire gave a brief talk about the variety of ways the
to them. Fire and Earth participated in the LSD panel where they
word drugs is used depending on the context and situation,
presented data about analytical testing of street LSD (see page
and then joined Ann Shulgin in a Q&A session where audience
12 for more details).
members were encouraged to ask questions about psychoac-
Lectures were given by Mind States newcomers V.S. tive-related topics. For details about this excellent event, see
Ramachandran, Jaron Lanier, and researcher David Nichols as
well as by many old favorites. Mistress of Ceremonies Susan
assacon.com.
Blackmore was stalwart in her task of keeping presentations
to their allotted time, causing some good-humored exchanges
between her and several speakers.
Speaking as a mother of three, Im glad someone has
to courage to provide the next generation unbiased
Word is that Mind States V will be held in Oaxaca, Mexico information about recreational drugsI told my kids, If
in September 2004. Updates and information can be found at you do drugs, please read Erowid first so I wont have to
mindstates.org. Jon Hanna and the Mind States crew have learned
someday identify your body in the hospital morgue.
how to put on a great conference, mixing the old and new, trying
out ideas while sticking with what works. Were looking forward An Erowid Visitor
to the next one.
Erowid Extracts No. 5 / November 2003 5
M EME C ULTIVATION

Limiting Liability by Earth & Fire Erowid

while Discussing Psychoactives


Aiding, Abetting and Conspiracy

T
he complex and sensitive nature of of civil liability is negotiated outside courts
our field of study not only presents (often by insurance companies and law firms) Not only can talking about future
thorny ethical issues, but also very and because civil action in the U.S. can be specific acts of your own get you in trouble,
real considerations concerning potential undertaken with very few requirements, it is but so can talking with someone else about
legal, social, and professional sanctions. hard to summarize the issues involved. All of their plans to break the law. Knowingly
Erowid work demands we take great care the guidelines for avoiding criminal liability providing information to help someone
when answering questions and discussing also help to reduce risk of civil problems. in the commission of a crime can be
topics related to potential illegal activities. prosecuted as aiding and abetting a crime or
This is especially true given the many Criminal Liability even conspiracy. It can be illegal to provide
people who work on the Erowid site, as one information to an individual whom you know
The primary concern most people have is intends to break the law, even if they do not
persons careless actions could endanger whether providing information or answering
others. Could we be sued if someone is hurt actually commit the crime.
questions could be illegal.
after taking a psychoactive they read about What is NOT considered conspiracy is
on Erowid? Could we be charged with Some concerns have arisen out of the providing the same piece of information
conspiracy for providing information about recent case of Psilocybe Fanaticus (PF), for general use by the public, even if an
how psilocybin-containing mushrooms are a company that sold Psilocybe mushroom individual ends up using the information to
grown? spores over the internet. The companys break the law. The definition of conspiracy
owner was charged with conspiracy to requires that all involved parties knowingly or
Unfortunately, there is no simple answer. manufacture psilocin (an active ingredient
Civil liability (individuals or companies intentionally agree to assist in the commission
in Psilocybe mushrooms and a Schedule I or planning of a specific crime.
suing each other) is a wide open field of law substance in the United States). One of
where there are few absolute rules. Criminal the reasons people have been concerned For instance, consider the following
liability is a little easier to address and there about this case is that a major element in question:
are some very clear rules we follow to avoid the conspiracy charge is the set of specific
breaking any laws. growing instructions PF included with the I have some Psilocybe mushroom
spores they sold. spores and have been having trouble
getting the fruit to grow well. Can
Civil Liability The PF case has not yet been resolved, you tell me what I can do to reduce
The First Amendment in the United but it is important to point out the distinction contamination?
States provides substantial, meaningful between pure speech and product sales. If
protections against both civil and criminal PF had merely told people how to grow Answering this question could be considered
liability. Unfortunately, because a great deal Psilocybes, they would likely have been conspiracy to manufacture psilocybin or
ignored by law enforcement. While it is psilocin. On the other hand, answering the
certainly possible to be guilty of conspiracy question:
KEY POINTS or aiding and abetting a felony through com- Can you tell me what common
munication alone, there are some fairly bright techniques people use for reducing
lines that one can avoid crossing. contamination when cultivating
1) Avoid discussing current possession
or future, specific illegal acts. Psilocybe mushrooms?
Talking About Illegal Acts
2) Do not provide recommendations or would not be conspiracy as long as there is
The primary thing people should know
suggestions, simply provide generic no reason to believe the individual intends
to avoid is discussing future, specific illegal
descriptions of factual data. to break the law using the information
acts or current possession of controlled
provided.
3) Refuse clearly when asked directly substances. Admitting publicly to having
for information that would assist a smoked cannabis in the past is almost Assuming the person asking does not have
crime. certainly not going to result in prosecution, a license to grow Psilocybe mushroomsnot
4) Do not provide specific information but talking about intending to smoke always a correct assumption, but a prudent
or answers to questions if there is cannabis after dinner could. A credible onethe first question implies that the
any suggestion that they might statement about either current possession of information might be used to engage in
be used in the commission of a an illegal substance or about specific future a specific future illegal act. The second
crime. illegal acts could be grounds for a valid search question in no way implies an intent to use
warrant. the information to break a law.

6 Erowid Extracts No. 5 / November 2003


Cannabinoids Neuroprotective?
by Earth Erowid

Research has begun to accumulate is now considered unlikely to account for


over the past few years showing that much of the protection, since cannabinoid-
cannabinoids are neuroprotective against receptor antagonists block the beneficial
brain injury resulting from toxins, effects and the doses of the cannabinoids
hypoxia, and head trauma. Cannabinoids given are very low.
If someone asks a question and sounds
are, loosely, chemicals that are similar in
like they might use your response in the Perhaps the current best guess for how
structure to the psychoactive components
commission of a crime, tell them you cant these chemicals provide their protective
in cannabis and/or chemicals that activate
or wont answer the question. Redirect effects is that their general dampening
the cannabinoid receptor system in the
the conversation to a new topic or end it of neural activity reduces excitotoxicity
body. Researchers have found protective
entirely. (damage caused by overly excited neurons).
effects not only from the plant-derived
One of the specific ways this happens is
cannabinoids such as THC, but also from
through the inhibition of the glutamate
Providing Information endogenous cannabinoids (those occurring
system in the brain. The glutamatergic
Although, by their very nature, libraries naturally in the body, such as anandamide)
neurons are part of the excitatory system
are open to everyone, there are those who and some synthetic pharmaceutical
in the brain; inhibiting glutamate reduces
would like to restrict access to information cannabinoids.
the activity of other neurons. At least in
to people they approve of. The research with the cannabis- some parts of the brain, activation of the
source cannabinoids, conducted in mice, CB1 cannabinoid receptor (a specific type
Erowid is founded on the belief that
rats, and in vitro, has shown remarkable of cannabinoid receptor) has been shown
everyone must have access to the same
effectiveness in reducing brain damage to block pre-synaptic release of glutamate.
information in order for there to be shared
from injected toxins, hypoxia, and head CB1 receptor activation is also known to
trust and responsible choices. Knowledge
trauma.1 Other research has found that inhibit certain calcium channels, directly
of psychoactives and their use is of
anandamide levels in the brains of rats reducing the production of nitric oxide
interest to researchers, physicians, anthro-
naturally rise after brain injury or death and other potentially damaging reactive
pologists, historians, reporters, lawyers,
and the cannabinoid system may play a oxygen species.1,4
teachers, students, politicians, as well as
primary role in limiting brain damage.2
the average person who lives in a world For more information and a more
surrounded by these potent substances. Because psychoactivity is considered complete list of references, see erowid.org/
an unwanted side effect, much of the extracts/n5/cannabinoids.shtml and read
Because we provide information to the current research is being done with the summary article Cannabinoids and
public, intended for no specific individual, synthetic cannabinoid system agonists. brain injury: therapeutic implications by
and for no specific purpose, our situation
is relatively clear. If we were providing
One synthetic cannabinoid, Dexanabinol
(HU-211), is already in phase 3 trials
Mechoulam et al. 2002.5
information for the purpose of helping (medium scale, involving humans) References
people break controlled substance laws, headed towards governmental approval 1. van der Stelt M, Veldhuis WB, Bar PR,
it would substantially increase our risk of as a neuroprotective pharmaceutical. Veldink GA, et al. Neuroprotection by
civil or criminal problems, but we have no Research conducted in Israel that gave Delta9-tetrahydrocannabinol, the main
intention of assisting anyone in breaking the active compound in marijuana, against
67 patients with serious head trauma ouabain-induced in vivo excitotoxicity.
law or encouraging anyone to use illegal either Dexanabinol or placebo confirms J Neurosci. 2001; 21(17):6475-6479.
psychoactives. similar research in rats showing reduced 2. Marsicano G, Goodenough S, Monory
damage and faster recovery among those K, Hermann H, et al. CB1 cannabinoid
Its clear that people will continue to use receptors and on-demand defense against
illegal substances whether they have access receiving the cannabinoids.3 Although excitotoxicity. Science. Oct 3, 2003;
to information or not. Hundreds of millions other promising head trauma treatments 302(5642):84-88.
of people in the United States alone have have failed in the demanding and complex 3. Knoller N, Levi L, Shoshan I, Reichenthal E,
phase 3 research trials, many interested in et al. Dexanabinol (HU-211) in the treatment
used an illegal plant or chemical. Reliable of severe closed head injury: a randomized,
information about these substances needs the field of neuroinjury are excited about
placebo-controlled, phase II clinical trial.
to be available to the public and there is the findings to date. Crit Care Med. Mar 2002; 30(3):548-554.
little question that this type of publishing The mechanisms by which the 4. Shen M, Piser TM, Seybold VS, Thayer
is well within both the spirit and the letter SA. Cannabinoid receptor agonists inhibit
cannabinoids reduce damage from both glutamatergic synaptic transmission in rat
of the law. While other rights outlined toxic and traumatic injury to the brain hippocampal cultures. J Neurosci. Jul 15,
in the U.S. Constitution have degraded are not yet fully understood. Although 1996; 16(14):4322-4334.
substantially, the First Amendment still some researchers have suggested that 5. Mechoulam R, Panikashvili D, Shohami E.
stands as a powerful protection of the right Cannabinoids and brain injury: therapeutic
the cannabinoids may offer protection implications. Trends Mol Med. Feb 2002;
to discuss sensitive topics without the fear through a strong antioxidant effect, this 8(2):58-61.
of prosecution.
Erowid Extracts No. 5 / November 2003 7
LOOPED REALITY
An Experience with Nitrous Oxide at the Dentists Office

by JK

Last year, I broke my teeth. I fell off cream cans, I thought the high would last a when asked how I was doing, I told them, not
my bicycle at speed (while sober; it was minute, Id feel great, and then Id be right feeling a thing. They turned it up, and kept
a mechanical failure) and broke the fall back to the real world. I didnt realize that working on their preparations. In 10 minutes,
entirely with my mouth. Needless to say, theyd keep a mask on my nose the whole they came back and the dentist said, So so so
this was not fun. The shattered jaw was time. So, in the chair, I was nervous to the so so how how how how how how are are are
set and has healed beautifully, but lacking point of trembling. My pain threshold is are are are you you you you you you you you
dental insurance I was unable to have my extremely high, but not high enough to take feeling feeling feeling feeling feeling now
needed tooth repairs done. A year later, it two extractions and extensive digging/cutting/ now now now now now now now?
had developed into horrible infection, the cleaning without being totally incapacitated.
I knew this was going to be fun.
bone had dissolved, and I was in urgent Boy, was I in for a treat. The dentist and
need of care. Enter the Supreme Tooth-Fu hygienist strapped the nosepiece on me and The world echoed and time stretched out.
Dental Master Artisan, a longtime friend grinned as if I was being indoctrinated into The dentist took his needle and injected me
of the family and a senior, trusted expert a secret club. with a hefty dose of lidocaine. The physical
in restoration. He also had a huge tank of sensation of the injection did not bother me
The feeling started at the tips of my
nitrous, and decades of practice with it. at all, but my sense of taste was still very
fingers. I noticed that my hands and feet
acute and I felt myself grimace a bit at the
That said, I was still completely terrified. didnt want to move around as much, though
chemical bitterness of the stuff, though that
Everyone Id asked about nitrous said yeah, they were still responsive. I ran through some
was short-lived as it soon numbed my tongue
you feel the pain, you just dont really give logical tests in my head to made sure I could
as well. The next thing I noticed was that my
a fuck. I didnt understand this. From my still think straight, and I could. Still scared,
synesthesia was going into overdrive, starting
limited youthful experiences with whipped I thought this was the best it would get, so
with my pitch/color/texture sense.
The chair lowered with a deep B thrum,
and then the drill screamed to life at its very
distinctive pitch, oscillating between high
registers of B and C# and slowing to an F to
F# when it bit angrily into my teeth. Colors
leapt out of the corners of my eyes as the
sounds around me became intensely musical
and I focused solely on their frequencies. The
sing-song speech of the adorable hygienist
was every bit as interesting to me as the R&B
crooning on the car radio that morning. There
was some pretty innocuous-sounding Vivaldi
(redundant? yes.) playing on the radio, and
at first it was echoing profoundly. It seemed
as if, while falling into the sky, the same five
note passage was playing over and over again
with a flange effectnot a repetition of notes
but of sound. It felt like I was looking at a
square grid of luminescent bluish white lines
on a dark blue background, rippling out to
infinity on the horizon. I studied that effect,
curious and aware of its existence, wondering

8 Erowid Extracts No. 5 / November 2003


what process the nitrous is interrupting or My physical body was completely across my body, overwhelming warmth, and
affecting in order to do that. Could it be an irrelevant at this point and ALL of my con- a strong inclination to smile and be happy
extreme short term memory loop, like some sciousness was focused on the sound entering about everything in life at that moment.
kind of auditory buffer that holds the last two my ears. It sounded as if I was listening to a Structurally the music and the brilliance of
seconds of low-frequency sound, as if the sampling rate the inversions used in the symphony suddenly
of the radio had been reduced to 2 or 4 kHz, as became clearI knew at that moment why
WHOA! I was jarred out of la-la land by
if the rate of processing my brain was doing he chose to ascend and descend, and why a
the dentist tapping on my shoulder, eager to
on the sound was dramatically accelerated certain sharp or flat was used at a certain point
show me the jagged-edged, broken tooth he
and I could now tell apart the individual to hint ever-so-subtly at a particular mood and
had pulled out of my head. I moved my
grains of sound making up the waveform. to advance the story.
tongue to the spot instinctively, and feeling
It was not slow motion in a pitch sense, but
nothing but bloody gum, I sighed in relief and I listened to most of the Fifth this way,
in a time sense, like the popular DJ effect of
knew that if I didnt even notice they were and have figured out so many things about
time-stretching a sound.
itand about Beethovens mind itselfthat
There were again spectrums of color I had not been able to unravel before. The
leaping over my closed eyelids as I listened. nitrous high allowed me to move forward in
The dentist said, So so so so Its difficult to pinpoint the exact colors of my understanding of aesthetics in general,
so so how how how how how soundI dont see reds and greens, but more not just a particular work.
how are are are are are are you iridescent, shiny flavors of light that make
me sort of itch inside, like various senses So, my teeth. By this point theyd cleaned
you you you you you feeling interconnected. While sober, Ill only see out all the yucky stuff from my gums and
feeling feeling feeling feeling it in my minds eye, seeing/feeling a certain taken out both lateral incisors, and were ready
now now now now now now? color/texture as the music hits certain to take casts. So they put me on oxygen, and
frequencies and timbres. Now, however, within 10 minutes I was completely back to
there was a light show dancing across my my normal self. I felt like part of my mind
vision and elaborate landscapes and flashes, was shutting off and I was reverting to
doing that, nothing could be very bad. Well,
except for the fact that the dentist, a kindly old
not unlike the Journey through Sound
introduction to Disneys Fantasia. It felt
stupidity, a door closed forever.
white-haired man who is perpetually smiling
very much like an orgasm, a tingle spreading Erowid.org/experiences/exp.php?ID=16335
and always ready with his razor-sharp wit
and grandfatherly wisdom, seemed extremely
strange; the familiar and jovial features of his
face were alien to me and he was a strange
dragonfly/elephant creature with melting New Books
skin. The hygienistand Im not making
this upwas Carrot Lady, a human carrot
LSD, Spirituality, and the Creative Process,
with a face and arms. I have no idea how
I drew this lateral association, but there
1 by Marlene Dobkin de Rios, Ph.D., and Oscar Janiger, M.D.
it was. It wasnt a visual hallucination, I An exploration of how LSD influences imagination and the creative process,
wasnt tripping, but my mind was in purely based on Janigers research. (Park Street Press/Inner Traditions)
lateral thinking mode and extremely strange
conclusions were drawn based on the wildest Animals and Psychedelics,
linked memories. 2 by Giorgio Samorini
Another completely ignored tooth Examines the role of psychedelics in the development of consciousness in
extraction later, they had settled into their all species. (Park Street Press/Inner Traditions)
curettage groove, cleaning out my gum
sockets, and I was in need of something Psychedelics and Magic Mushrooms,
else to focus on; they had fallen silent. So I
concentrated on the colorful, comfy music,
3 by Peter Stafford
Two new books exploring various aspects of psychedelics. Based on chapters
and just in time: Beethovens Fifth started
from the classic book Psychedelics Encyclopedia. (Ronin Publishing)
playing, and despite its being popular to the
point of cliche, it is one of my favorite pieces
Psychedelika: Kultur, Vision und Kritik,
of music. Im a composer and I work a lot
with orchestral music. Ive never, ever heard
4 Edited by Wolfgang Sterneck
it like this before, though, not on any other German-language anthology with discussion of the history of psychedelia
substance (I was into weed, LSD, and meth- and its role in hippie and techno culture. Includes 80 b/w images of art.
amphetamine a lot during my teenage years) (Nacht-Schatten Verlag)
and never by concentrating while alert.

Erowid Extracts No. 5 / November 2003 9


MYTH DEBUNKING by Fire Erowid

Do Undercover Police Have to


Identify Themselves?
Entrapment and Deception by Law Enforcement

Entrapment an entrapment defense. If the prosecution can


These types of myths are generally based show that the defendant agreed to participate
on the belief that it is illegal for a police too quickly or had a record of similar crimes
officer to entrap a citizen into committing a in the past, the entrapment defense rarely
crime. Following this theory, many people succeeds.5 One example of such a case
Brief Description of the Myth believe that related actions by police, such was U.S. v. Bogart (1986) in which Bogart
There is a persistent rumor that if you as lying about their identity, would also be agreed to sell presidential campaign posters
ask an undercover police officer or police illegal or invalidate a prosecution. While to a police informant. When the informant
informant if theyre a cop, they are required a claim of entrapment by police can be arrived to purchase the posters, he informed
to tell you. Based on this myth, many people used as a defense in a criminal case, it is Bogart that his only method of payment
believe they can safely conduct illegal trans- both uncommon and rarely successful. was with cocaine. Though Bogart initially
actions just by making sure to ask Are you Additionally, police entrapment itself is not refused, he eventually agreed because he
a cop? first. illegaljust potential cause for a not-guilty needed the proceeds from the sale. He was
verdict. arrested and his entrapment defense was
This idea is widespread and like many denied based on his predisposition to
such myths, is most often transmitted by Loosely defined, entrapment is a situation commit the crime.6
word of mouth. Examples can also easily in which, if not for the actions of the police
be found on bulletin boards and newsgroups, officer or police informant, the defendant Are Police Allowed to Lie?
in subculture publications, and in the media. would not have committed the crime. This
The question of whether or not the
The major variations of the myth include: defense is generally only successful in
police may lie during the course of their
situations where law enforcement officers
Police have to identify themselves if work goes hand in hand with the question
create a criminal plan, plant the idea of that
specifically asked whether they are law of entrapment.
plan into an otherwise innocent persons
enforcement.
mind, and then instigate the plan for the It is well accepted that deception is
Example: Are you scared that your purpose of prosecuting the suspect. often necessary to catch those who break
friend or enemy is an undercover
The mere presentation of an opportunity
cop, just ask, they are required to
or request by an officer that an individual Factors Considered
tell you if they are reporting to law in an Entrapment Defense
commit a crime does not qualify as
enforcement.1
entrapment. An officer may engage a citizen
Undercover officers arent allowed to in conversation and ask to buy an illegal
1) The character of the defendant (whether
initiate a drug sale without pre-existing substanceeven if they have no reason to the defendant was more predisposed
suspicion.2 suspect the person of illegal activity.2 They to commit the crime than the ordinary
may offer to sell an illegal substance and citizen; e.g. having a record of illegal
Example: An undercover cop comes activity of this sort).
arrest the buyer after the sale.
up to you and asks, Do you want to
2) Who first suggested the criminal activity.
buy some drugs? You say, Yes, and They can go out of their way to help a
they arrest you. THAT is entrapment, person to commit a crime. What they cant 3) Whether the defendant engaged in the
activity for profit.
and will be thrown out.3 do, is unduly persuade, threaten, coerce,
or harass the person, such that a normally 4) Whether the defendant demonstrated
Undercover officers arent allowed to ask reluctance (and not just no thanks, well
law-abiding citizen would participate in the ok: more like repeatedly refusing and
for an illegal drug by name.
unlawful action. then eventually, months or years later,
Example: He tells me that giving in).
Unfortunately, even in cases where the
[undercover police] cannot ask you 5) The nature of the governments induce-
government does induce a crime, evidence
for drugs by name, or even common ment (how much did they persuade,
that the defendant was predisposed to threaten, coerce, or harass).
slang terms. They must call it
committing the crime is likely to undermine
something else, like fun stuff.4

10 Erowid Extracts No. 5 / November 2003


the law. There is no question that police Possible Sources of the Myth lie, break controlled substance laws, ask to buy
officers are allowed to directly mislead and/or The myth that undercover police must substances by name, offer drugs for sale and are
deceive others about their identity, their law admit to being police if asked has been not required to identify themselves during the
enforcement status, their history, and just
about anything else, without breaking the law
around since at least the mid-1970s. In
addition to the belief that entrapment is
course of their undercover investigations.
or compromising their case.5 Conversely, it illegal, it may have roots in requirements References
is illegal for an ordinary citizen to lie to the that law enforcement identify themselves in 1. Bob L. Babylon and other important stuff.
police in many jurisdictions. some other situations. Posted to St. Louis Raves (Yahoo Groups).
Jun 30, 1999. Retrieved Oct 2003 from
Are Police Allowed to Break The Law? 1) Most on-duty police are required to wear groups.yahoo.com/group/stl-raves/message/3725
Police officers working undercover have both a uniform and a uniquely numbered
badge identifying themselves as police. 2. Kukura TV. Undercover Investigations And
exceptions from certain criminal laws. For The Entrapment Defense. Law Enforcement
instance, law enforcement officers directly 2) Police must generally identify themselves Bulletin. Apr 1993.
engaged in the enforcement of controlled before executing a search warrant or
substance laws are exempt from laws 3. F r a n k M . A n y O t h e r B r i t s H e r e ?
arresting someone.
surrounding the purchase, possession, sales Usenet.alt.support.girl-lovers. Jun 3, 2002.
or use of illegal substances.7 3) Though it varies by jurisdiction, there are 4. Spyder. Undercover Cops at Burning Man.
some situations in which off-duty police Piss Clear. Aug 27, 2003; 19:2.
This means that theres no way to may be required to identify themselves,
identify an undercover officer based on their including if confronted by another police 5. Greaney GM. Crossing the Constitutional
willingness or refusal to use an illegal drug. officer or before acting in their capacity Line. Notre Dame Law Review. 1992; 67:745.
Reverse stings are common in the enforce- as a police officer. 6. Lord KM. Entrapment and Due Process.
ment of controlled substance laws. In a
Florida State Univ. Law Review. 1998;
reverse sting operation, a police officer sells The simple summary is that undercover
25(3):463.
drugs that have previously been confiscated police are given a great deal of latitude when
and then arrest the buyer. investigating suspected criminals. They may 7. 21 U.S.C. 885(d) of the U.S. Code.

Organizational Updates
MAPS (maps.org) TRIP Magazine (tripzine.com)
On Tuesday, September 23, 2003, the Institutional Review Issue 10 of Trip is on schedule for a December release, including
Board reviewing a MAPS-sponsored study of MDMA-assisted pieces by Earth & Fire Erowid, Hakim Bey, Erik Davis, Mark Pesce,
psychotherapy for Post-Traumatic Stress Disorder approved the and Sheldon Norberg. Meanwhile, Trip recently released Terence
study protocol. This study is poised to be the first research into McKenna: The Last Interview, a two-CD interview with Erik
the therapeutic use of MDMA ever conducted in the U.S. Dr. Davis, the last recording of McKennas career, featuring Terences
Mithoefer and MAPS have been struggling to obtain IRB approval final thoughts on entheogens, culture, the future, his own spiritual
since 2001, when the FDA approved the study. The last remaining beliefs, and the grim problem of cancer, death and dying. Another
hurdle is for Dr. Mithoefer to obtain a Schedule I license. MAPS new release is Tales From The Trip Side, a silly, psychedelic sketch
has also been busy responding to media regarding the retraction of comedy DVD featuring Seattle comedians in drug-inspired comic
the Johns Hopkins MDMA neurotoxicity study published in Science. situations.
Traffic to the MAPS website tripled in September due to the MAPS
response to and coverage of the scandal. SSDP (ssdp.org)
Students for Sensible Drug Policy has had an interesting summer
DrugSense / MAP (drugsense.org) with long time friend and leader Shawn Heller leaving as National
DrugSense/Media Awareness Project has launched Drug Policy Director to further pursue his education. Darrell Rogers is running
Central (DPC) to support the efforts of over 150 drug policy reform SSDP as interim National Director. SSDP plans on having its chapters
organizations worldwide by providing affordable web and internet and students play a large and pivotal role in the New Hampshire
services. Non-profit organizations dedicated to drug policy reform Democratic primary in January. Their goal is to mobilize hundreds
that lack funding can benefit from a grant application process. of organized SSDP activists and saturate the Democratic presidential
DrugSense/MAP now offers German, French, Canadian and Dutch candidates forums with SSDPs drug law reform platform.
versions of its news clipping and excerpting service, and MAP
OnAir, targeting broadcast media. Bluelight (bluelight.nu)
The survey that Bluelight helped put together for a Texas
CCLE (cognitiveliberty.org) A&M Department of Sociology study (Technology, Youth and
The CCLE has been busy working to submit a legal brief in the Proliferation of Drug Use) funded by NIDA was completed on
the Supreme Court case Sell v. United States. In the brief, CCLE August 25, 2003 and the data is currently under review. Bluelight
argued that cognitive liberty is protected by the First Amendment, has added a new interactive photo gallery where members can upload
and guarantees the right of each person to self-determine their own images into either member-only or public galleries, and registered
neurochemistry. The brief is available on the CCLE website. posters now have the new option of starting their own blog.

Erowid Extracts No. 5 / November 2003 11


LSD A NA LY
LYSI
SIS
S
Do We Know Whats In Street Acid?

by Fire & Earth Erowid

A
ccording to the 2002 National result of normal variations in experience Substances Act, tight restrictions were put
Household Surveythe largest from one person to another or one situation in place over who is allowed to analyze
survey of psychoactive drug use in to another? and research controlled substances. Only
the United Statesmore than 10% of people those labs or individuals who are licensed
Some people believe that there is no
over the age of 12 say they have tried LSD at by the DEA are allowed to handle Schedule
pure acid on the street these days: that
some time in their lives. The number is more I substances such as LSD.
the last clean acid was made by Sandoz
than 15% among those between the ages of
or Owsley.2 Others believe that acid is In 1972, the BNDD (The Bureau of
18 and 25.1
acid: that differences in purity dont play a Narcotics and Dangerous Drugs) requested
Although it has now been over 60 years significant role in different effects, which are that labs collect names and addresses for
since the discovery of LSDwith thousands instead explained as the result of differences anyone submitting controlled substances
of papers published about its chemistry, in dosage, set, setting, and individual for testing.3 Then in 1974, the DEA issued
pharmacology, and social impactthere are reactions. Yet a third opinion is that there firm guidelines that required licensed
still huge questions about what is sold on the are variations in purityfrom incomplete laboratories to stop providing quantitative
street as acid. syntheses, poorly purified material or results for anonymously submitted samples
degraded materialas well as a variety of of scheduled substances.4 Now, unless a
chemicals such as ALD-52 or isomers of LSD person is willing to walk in to a lab, give
Good Acid vs. Bad Acid that might be sold as street acid. their name, show identification (which would
One of the most persistent ongoing be recorded in the labs records), and then
One of the primary arguments against the
debates about street acid is why people submit the sample (thereby volunteering
premise that differences in LSD experiences
report that different batches are experientially proof of having committed a crime), labs
are the result of differences in quality of
different in their effects. Is it the result of are not permitted to provide information
material has come from people weve spoken
different qualities of acid? Is it the result about how much of any chemical is present
to who have distributed and aliquoted acid
of different dosages? Or is it simply the in the sample. Not surprisingly, most lawyers
in the past. One such person described how
would advise against such an action.
some recipients of his LSD would go on at
GLOSSARY length about how distinct and how much Additionally, even for qualitative
better one type of blotter was than another. data (simply listing what chemicals are
Yet, often, both types had been aliquoted by present) the DEA does not allow labs to test
Aliquot to divide or measure into this chemist on the same day, from the same anonymously submitted samples without
equal parts. batch of liquid, onto similar blotter paper special permission. It is through one such
bearing different designs. approved lab that the EcstasyData project
Isomers two substances that are
is, with some difficulty, able to provide
composed of the same ele-
ments in the same proportions qualitative results for street ecstasy tablets.
The Legality of Testing
but with a slightly different ar- Though these rules against testing are
rangement of atoms. These questions should be trivial to
only DEA guidelines (we do not believe
address, yet for several years we have been
they are part of any law or publicly available
d-LSD (or d-LSD-25) is the known trying to collect reliable information about the
active form of LSD first synthe- official policy), representatives of at least one
contents of street LSD, with minimal results.
sized by Albert Hofmann. lab we spoke with have been threatened with
Unfortunately, getting street LSD legally having their license revoked after participat-
iso-LSD an isomer of d-LSD be- analyzed is extremely difficult for anyone ing in research the DEA didnt like. Since
lieved to be non-psychoactive. outside of law enforcement. Starting in the DEA licensing is required in order to handle
early 1970s with the passage of the Controlled Schedule I substances, labs that work with

12 Erowid Extracts No. 5 / November 2003


such chemicals are understandably reticent no papers published, using reproducible lab
PharmChem Summary of
to risk their livelihood by going against these methodology, that attempt to characterize the
Street Acid Analysis
guidelines. impurities found in street acid. (1969-1975)
PharmChem Data 2200 samples submitted
The Difficulty of Testing In the early 1970s, prior to issuance of 87% contained LSD
Testing LSD is technically more difficult the DEAs guidelines, there were a few labs and no other psychoactive
than the testing of many other common that actively analyzed street LSD. The most 5-500 g per dose
psychoactives. This is because the dose prominent of these labs was PharmChem, 75 g average dose
range is very low and because its a complex based in Palo Alto, California. Between
10 labs produced results
molecule. There are simple tests available 1972 and 1978, PharmChem solicited users but most from PharmChem itself
for identifying the presence of LSD (using to send in samples of chemicals purchased Testing methods were not described.
thin layer chromatography or immunoassay). on the street. They then worked with labs
But detecting and characterizing impurities around the country to provide testing results
or quantifying the exact amount of LSD in for the submitted samples.
a given dose unit is more complicated and In March 1977, PharmChem published
Prior to 1974, PharmChem published
requires an experienced analytical chemist a review of the street drug analysis they had
both qualitative and some quantitative testing
with specialized equipment and an interest done in the United States and Canada between
resultsincluding microgram dosages for
in the topic. 1969 and 1975. Looking at a total of 2200
street LSDin their print newsletter. Each
samples submitted as acid or LSD, they
Unfortunately, because of the combination month they would publish a list of hundreds
reported that 87% of the submitted samples
of DEA restrictions and the difficulty of of samples that had been submitted, including
alleged to be LSD were d-LSD with no other
testing, there may be no labs in the United information about what the submitter believed
psychoactive drug present. In LSD-positive
States currently licensed and qualified to do the substance to be, where and when it was
samples, they found a range of 5 to 500 g
anonymous testing of LSD. purchased, how much it had cost, a physical
with an average of 75 g per dose.5
description of the material, and what the test
results were for the sample. Unfortunately, Interestingly, people who submitted
The Existing Data they failed to describe their testing methods. samples to PharmChem also often submitted
The difficulty we encountered in getting We believe, based on talking to Alexander comments about whether they believed that
currently-circulating samples tested led us to Shulgin and a former PharmChem employee the acid contained speed or strychnine.
collect what historical information we could who worked there after their Analysis Although no strychnine was ever detected
find about the contents of street LSD. Anonymous program had ended, that they in any of the submitted samplesand
used thin layer chromatography to detect both only a few tested positive for methamphet-
Even here, the resources are scarce. To
the presence of LSD, and what could only be aminePharmChem reported that the more
the best of our knowledge, there have been
estimates of the quantities present. LSD that was present in a dose unit, the more
likely the submitter was to think it contained
strychnine.
Pharmchem Test Results Following the issuance of the DEAs 1974
( Examples from December 1973 )
guidelines, PharmChem and other labs quickly
Alleged stopped publishing quantitative data.
Content Actual Content Description

LSD 40 g LSD white blotter paper DEA Data


LSD 90 g LSD + 10 g iso-LSD yellow tablet The second major source of testing data
is the DEA itself. Unfortunately, their law
LSD 60 g LSD yellow-green powder
enforcement mission does not necessitate
LSD 55 g LSD + 15 g iso-LSD blue tablet, microdot that they provide the public with the vast
LSD 140 g LSD + 40 g iso-LSD white blotter paper quantities of information they generate in
LSD 65 g LSD white double-dome tablet their pursuit of drug law violators. Though
LSD 55 g LSD + 10 g iso-LSD white blotter paper, Mr. Natural occasionally they publish average dosages
LSD 45 g LSD pink spot on white/red/blue blotter for the street acid they confiscate, they are
LSD 55 g LSD orange tablet not necessarily neutral in their reporting.
Because there is no oversight or external
LSD 60 g LSD orange tablet
verification of any of their data and because
LSD 130 g LSD amber gelatin square of potential conflicts of interest between
LSD 60 g LSD + 20 g iso-LSD magenta spot on white blotter science and law enforcement, their data
LSD 100 g LSD + 10 g iso-LSD spot on white blotter paper must be considered carefully.
LSD 150 g LSD + 20 g iso-LSD spot on white blotter paper
According to the DEA, the average dose
LSD 45 g LSD blue tablet of LSD on street blotter is between 20 and
LSD 80 g LSD + 20 g iso-LSD beige spot on white blotter 80 micrograms (g). Based on this, they
LSD 60 g LSD white tablet now consider a standard dose of LSD

Erowid Extracts No. 5 / November 2003 13


as low as a couple of micrograms to doses tested only 12 samples alleged to be LSD and
DEA Information about LSD
near 200 g per hit. only half of these actually contained LSD. Of
(2003)
these, they reported doses ranging from 5 to
20-80 g per street dose unit Unfortunately, Microgram is not scientifi-
168 micrograms. Additionally, the person
cally rigorous in its reporting of the DEAs
50 g standard dose we communicated with from their lab said
testing results. No information is provided in
62% average purity in LSD crystal seized that results for the two lowest dose samples
The Blotter Index about which labs provided
were considered unreliable. The Dutch
95% + purity in some LSD crystal seized which data and what methods were used for
lab reports that they use HPLC for their
Note possible conflicts of interest in reporting. detection or quantification. Likewise, the
quantification and occasionally use GC/MS
DEAs data about average doses is difficult
to verify results.8
to reproduce or verify, as their methods for
averaging are not described and they do not Although we have been unable to get
to be around 50 g. They also report that
provide information about how many doses results from or clear documentation about
crystal LSD they have seized averages about
of each design were produced, seized, or ongoing testing programs in other countries,
62% d-LSD (with the rest made up of other
tested. we believe that testing programs for street
isomers or impurities) but that some is 95-
drugs exist in France, Spain, Austria, and
100% pure.6 The dose per unit for individual designs
Switzerland, most funded by the national
described in The Blotter Index also shows an
For more than 35 years, the DEA and their governments. Most of these programs are
average of about 20-80 g per hit. There is
predecessor organizations have produced a oriented towards testing ecstasy tablets,
speculation that some of this variation might
privatein fact almost secretinternal cocaine, or heroin and it is unclear whether
be the result of inconsistency in the dipping
publication called Microgram. Prior to they could reliably detect or quantify various
process resulting in higher doses on one edge
2003, this publication was available only forms of LSD, let alone detect minor
of a sheet than the other. A copy of this article
to the DEA and the labs and chemists they impurities.
is available in the Erowid LSD Vault.
worked with. A wide variety of information
about the street use of scheduled substances
Other Countries New LSD Testing
and about law enforcement action has been
Other countries have different regulations
published in Microgram. Over the years, it After being disappointed by our historical
than the United States regarding testing of
has included information about LSD blotter searchfinding little to help resolve the
controlled substances and some European
designs tested by DEA offices around the enduring debate about what differences
countries appear to have easier access to
United States and the lab techniques used to exist between batches of street LSDwe
quantitative testing.
test them. They have also regularly printed continued to seek a lab with the necessary
images of street acid and sometimes included The Netherlands have an ongoing free skills to perform LSD analysis. Earlier this
quantitative information. testing program where individuals can bring year, we were able to find a licensed lab with
in a sample of any street drug to be tested. access to an analytical standard of LSD as
In 2002, in response to Erowids interest
We were given a summary of their testing well as a lab sample from 10 years earlier that
in learning more about the DEAs past
results that shows that they receive very few had been stored under nitrogen in freebase
LSD analysis, a Freedom of Information
samples of street acid to be tested. Of 600 form. They also had access to a street sample
request was filed for a 10-year-old issue of
samples submitted in 2001 and 2002, they in the form of a small brown microdot.
Microgram. The request was denied and is
currently being appealed.
Still seeking the information, we were

Photo 2003 Erowid.org


soon informed that some obscure libraries
in the United States happen to carry back
issues. From these libraries and from Erowid
friends, we have been able to piece together a
collection of back issues of the publication.
The latest year of Microgram we have
access to is 1996. In that year, the DEA
published a handful of blotter images and
a small number of quantitative test results.
The doses they report were between 28 and
78 micrograms per hit of blotter.
More interestingly, in 1987, the DEA
published an article in Microgram titled The
LSD Blotter Index by Franzosa, Harper, and
Crockett. This article is a catalog of hundreds
of blotter designs seized by law enforcement
between 1976 and 1986, including quantita-
tive information for many of them.7 In this
index, the reported dose per unit ranges from

14 Erowid Extracts No. 5 / November 2003


Information about these brown microdots
Wavelength: 254 nm
was reported to Erowid from around the
United States between August 2002 and May
2003. Additionally, the newly public version
of the DEAs Microgram reported a seizure
of two such brown microdots in Owatonna,
Minnesota in April 2003. 9 Though the
Microgram mention did not include quanti-
tative information, most reports (though not
all) have described these microdots as very
weak, suggesting a low dosage per tablet.
The lab we communicated with used
high performance liquid chromatography
(HPLC), ultraviolet (UV) absorption mea-
surements, and liquid chromatography/mass
spectrometry (LC/MS) to determine what was Figure 1. HPLC of LSD Reference Standard Peak Ret Area Percent
No Time Area
in the microdot. Using the same methods, 1 9.05 7855472 100.0
the microdot results [Fig. 1] were compared
against both the high quality analytical
standard [Fig. 2] and the 10-year-old lab
sample [Fig. 4].

Testing Methods Wavelength: 254 nm


The most useful of the tests performed
was HPLC followed by UV absorption. For
this, the sample is dissolved in a solvent (such
as water or methanol) and is then injected
into a long, thin tube called a column. The
column has a specially prepared coating on
the inside that causes different chemicals to
travel at slightly different speeds as they move
through the tube.
At the end of the column is a detector
that senses when the chemicals emerge
from the tube. The output from the column
is subjected to ultraviolet light at a chosen
wavelength. For this test 254 nanometer light Figure 2. HPLC of LSD Street Sample Peak
No
Ret
Time Area Percent
Area
was used, a common detection frequency. 1 7.20 325859 6.7
2 7.67 221520 4.6
The time the sample takes to move 3 8.12 1057672 21.8
through the column is called the retention 4 8.44 212559 4.4
time and is marked along the x-axis (bottom 5 8.90 2215196 45.6

side) of figures 1, 2, and 4. a retention time of 9.047 minutes. Using 6 9.50 820631 16.9

an electro-spray mass spectrometer, the lab


The y-axis (left side) of the charts
verified that this reference standard had the
shows how much UV light was absorbed by
correct molecular weight (323) for d-LSD.
the material coming out of the column at a
This material was further verified by checking
particular point in time.
that its UV absorption profile had the correct retention time matches almost exactly that
Each peak in the chart represents when peak absorption at around 320 nanometers. of the reference standard (small variations
each chemical component of a sample in retention time are normal) and mass spec-
This all verified that the new reference
reached the end of the column. The small trometry verified that d-LSD was present in
standard appears to be very pure d-LSD.
bumps nearest the left side of each chart the sample.
Although there are some extremely minor
are called solvent fronts and are usually
perturbations in the baseline around the Since each peak represents a chemical
ignored because they represent residue
LSD peak, these are well within the margin present in the sample, and there are several
chemicals carried through the system with
of error of the equipment. significant peaks besides the one known to
the initial wave of the injected solvent.
be d-LSD, that leaves us with the important
The HPLC + UV output for the new What Is in the Microdot? questionwhat chemicals do the rest of the
reference standard of d-LSD (Fig. 1) is The HPLC + UV output for the street peaks represent? Relative amounts of each
quite simple. In the middle of this figure, microdot (Fig. 2) shows a central peak on chemical can be measured by comparing
there is a single very clean, clear peak with the graph that is without question d-LSD. Its what is known as Area Under the Curve
Erowid Extracts No. 5 / November 2003 15
and found no psychoactivity. More recent chemicals, although without doing work
rat experiments have found that rats given to characterize exactly what those peaks
iso-LSD in a discrimination study dont represent, its impossible to say what they
respond as though its d-LSD.12 It is an are. Chemists weve talked to suggest they
open question, however, whether high levels might include other isomers of LSD and
of iso-LSD could possibly alter the effects material such as lumi-LSD (LSD with an
of LSD, either through activity at a different additional oxygen) or potentially unconverted
serotonin receptor type than d-LSD triggers ergotamine.
or through some other mechanism.
It is certainly not very reassuring that
As far as we know, no research has neither the lab testing the brown microdot
been done to determine whether isomers nor the British scientist who produced the
of LSD can potentially reduce or alter the 1984 UNODC results was able to determine
receptor binding or otherwise modify the what the second largest peak was in the tested
Figure 3. HPLC + UV Profile from
pharmacodynamics of d-LSD. At this point, street acid. We are guessing its an oxidative
UNODCs 1984 Street Sample of LSD
iso-LSD is mostly believed to be inert and product or lumi-LSD, but at this point we
simply represents wasted lysergic material dont know.
since it is in the wrong configuration to be
Could those additional peaks be psycho-
(AUC), shown in the table below the graph. psychoactive.
active by themselves? Could they contribute
In figure 2, peak 3 (at 8.12 minutes) is noticeably to the experience? Most experts
10-Year-Old Lab Sample
nearly half the area of the d-LSD peak and dont think so, but there is remarkably little
The last HPLC + UV graph (Fig. 4) shows
peak 6 (at 9.5 minutes) is a little over a third hard data to say with much certainty.
a lab sample of LSD freebase that had been
of the area of the d-LSD peak. This suggests
stored under nitrogen for more than ten years.
that the chemicals represented by those Quantity
The lab said that the sample had started as
peaks are present in the microdot sample in Finally, by having a reference standard
extremely pure d-LSD but did not have any
quantities one-half and one-third of the total of known concentration, it is possible to
record of previous analysis results. We can
d-LSD present, respectively. Because the interpolate the dose of d-LSD on the single
see that the number of secondary peaks is far
exact retention times for specific substances brown microdot that was tested. By using
lower than with the brown microdot. The
can vary quite a bit, based on factors such as the Area Under the Curve for the reference
three tallest peaks appear to coincide with the
what type of solvent and column were used, standard and the total amount of d-LSD
three tallest peaks in the brown dot, and the
retention time cannot be used by itself to injected for that result, in this case 1.49 g,
9.0 peak was confirmed to have the correct
identify a substance. then comparing the total areas under the d-
UV absorption pattern for d-LSD. The lab
LSD peaks (in this case, the brown dots result
We believe that peak 6 is iso-LSD, believed the peak at 9.6 to be iso-LSD based
is about .28 the total area of the reference
an isomer of LSD. The lab guessed this on the UV and mass spectrums.
standards peak), and finally dividing this
peak to be iso-LSD based both on its UV
The rest of the small peaks in that area of by the portion of the street sample that was
absorption profile (image not shown) and on
the graph are likely other lysergic-structure injected (in this case 2%), we can estimate
their analysis of results of their LC/MS work
(also not shown).
This is also confirmed by a 1984 article
published by the United Nations Office
on Drugs and Crime, 10 which discussed
analytical work done in the United Kingdom.
Figure 3 is an image from this paper showing
the HPLC + UV profile for a street sample
tested in 1984. The similarities to the results
from the brown microdot are striking. This
paper identifies peak 4 (the equivalent to peak
5 in the microdot sample) as d-LSD, peak 5
(equivalent to microdot peak 6) as iso-LSD,
peak 3 (equivalent to microdot peak 4) as
most likely unconverted ergotamine, and says
peaks 1 and 2 are unidentified.
Iso-LSD is considered non-psychoac-
tive. Papers in the late 1950s reported low
or no activity for iso-LSD, including a very Peak Ret Percent
Area
interesting report published by Sandoz Figure 4. HPLC of 10-year-old No Time Area
1 8.20 488347 14.3
comparing activities of several lysergic LSD Reference Sample
2 9.00 2660857 77.7
acid derivatives.11 Albert Hofmann reported 3 9.61 274704 8.0
having tried iso-LSD at doses up to 500 g

16 Erowid Extracts No. 5 / November 2003


the total quantity of d-LSD in the brown dot. dot street samples were estimated to have References
According to this analysis, with a margin of approximately 21 g per unit. This value 1. National Survey on Drug Use and Health
error of about 10%, the brown microdot was consistent with widespread reports that (formerly the National Household Survey on
contains 21 g of d-LSD per tablet. effects produced by the brown microdots Drug Abuse). Substance Abuse and Mental
were weak. Health Services Administration, 2002 data.
As a side note, if we assume that most of Retrieved from samhsa.gov/oas/nhsda.htm
the secondary peaks around the d-LSD peak Erowid has been working for several
are lysergic compounds, a rough estimate years to find qualified analytical chemists 2. Eisner B. LSD Purity: Cleanliness is Next to
of the total mass of these would be around who have both the time and interest to look Godheadliness. High Times. Jan 1977; 17:
73-75.
50 g. It is possible that whoever aliquoted at the complex issue of LSD purity and
these microdots was working with impure independent quantitative analysis. Over 3. PharmChem Newsletter. 1972; 1(2):1.
crystal and had intended to make 50 g the past three years, we have interacted with
4. PharmChem Newsletter. 1974; 3(4):1.
doses. only one lab willing and able to perform
a detailed quantitative analysis. Out of 5. Street Drug Analysis and Drug Use Trends
Confirmation of Results fear of official scrutiny, they are unlikely 1969-1975. PharmChem Newsletter. 1977;
After hearing that we were interested in to perform any future work. The lab that 6(3):2.
learning more about the contents of street provided the rough quantitative estimate 6. Drug Enforcement Administration. LSD
LSD, an anonymous individual contacted us did so only on the condition that they not be Manufacture. DEA Website Intelligence
and volunteered to send a brown microdot to identified. Reports. Retrieved May 2003 from
a lab for testing. This microdot was tested by www.usdoj.gov/dea/pubs/lsd/lsd-5.htm
Independent academic analysis of
a DEA-licensed lab that positively identified
controlled substances is substantially limited 7. Franzosa, Harper, and Crockett. The Blotter
d-LSD in the sample.
by fears of license revocation or harassment Index. Microgram. Jul 1987; 10(7).
We also received results from an by the DEA. Labs are concerned about 8. Vervaeke H. Personal Communication. Mar
independent lab that had recently tested a cooperating with groups they expect the 2003. drugsinfo.nl/testen/
brown microdot. Using a cruder testing DEA to disapprove of. The DEA itself has
technique, this lab was able to roughly 9. Drug Enforcement Administration. Microgram.
not published scientifically rigorous analyses
estimate the dose of the microdots at Apr 2003; 36(4).
of street acid and there are unresolved issues
around 20 micrograms, give or take 50%. about what is sold as acid in the black 10.Humphreys IJ. The Work of the Drugs
These results were produced using thin market. Intelligence Laboratory, Home Office Forensic
layer chromatography and comparing the Science Service. Jan 1984. Retrieved from
We are left with the knowledge that, at unodc.org/unodc/en/bulletin/bulletin_1984-01-
results against three reference standards
this time, there is not enough information to 01_1_page005.html
of known concentration using a UV light.
resolve the good acid / bad acid debate.
This technique is not a reliable quantitative 11. Pharmacologic Properties and Psychotogenic
We will continue to watch for new data on
method, but it was reassuring that two labs Effects of some Lysergic Acid Derivatives:
this topic and hope this work can inspire
independently arrived at approximately the Comparison with Delysid (LSD-25). Internal
other investigators to look more closely at
same value from two different samples of the Sandoz Publication, 1958. Retrieved from
the issue. Perhaps university researchers erowid.org/references/refs_view.php?id=6084
same dose form.
will be inspired to contact Erowid about
Because this matches most of the
experiential reports weve received and the
follow-up work. 12. Anonymous. Personal Communication. 2003.

estimates of experienced LSD users, we


believe this quantitative estimate is correct.
The Truth About Mugs
Summary
If you havent yet seen them,
The results of these analyses showed we now have Erowid Mugs!
that the brown dot samples of street acid
contained d-LSD, as well as several other For those members who spend
major components. One of these substances their day in an office, who already
was identified as iso-LSD, based on molecular have an Erowid t-shirt or who just
weight, UV absorption pattern, and similarity enjoy their coffee or tea.
to published HPLC results of a street LSD These 15 oz. black mugs bear
sample. Another component was suggested the Words design used previously
to be lumi-LSD, but a clear molecular weight
on one of our t-shirts. The large
was not obtained and no reference standard
Erowid is made up of hundreds of
for lumi-LSD was available. Three other
small words and printed in yellow
chemicals present in the sample, making
lettering. Available with new
up about 15 percent of the total detected
memberships or renewals.
material, have not been identified.
Erowid.org/donations/
Using AUC from the HPLC + UV and
rough estimates using TLC, the brown

Erowid Extracts No. 5 / November 2003 17


THE IMPORTANCE OF
Measured Doses
by Fire Erowid & Spoon

In theory, most people seem to understand than an equal-sized pile of fluffy powdered rest, there is no way to identify its contents.
the concept that psychoactives can be mescaline. Likewise, two exactly equal-sized
2) Measuring a series of doses that are
dangerous or extremely unpleasant if taken piles of mescaline can include parts with very
different weights. Each dose goes into its
at the wrong dosage. But in practice, many different densities. Powders can go from
own capsule, which is labelled in indelible
people dont take the necessary precautions to fluffy, with low density, large crystals, to
ink as to its contents and quantity (some do
reduce the chances of such an overdose. cakey, to dense crystals more like table salt.
this in code). The variety of doses lets a
While the difference between powder and a
person choose how much they would like to
solid crystal would be apparent to the careful
Principles of Measured Doses ingest. The main problem with this method
eye, the difference between two slightly
is that the ink can eventually wear off of a
1) Use an accurate scale every time different densities of powder might not be.
capsule.
individual doses are prepared, especially Obviously, these problems are even worse
for substances active at less than 50 mg. when comparing two different substances. 3) Using liquid measuring techniques. A
known quantity of material is dissolved into
2) Demand that individual doses purchased Another issue arises when eyeballing
a known volume of liquid (usually alcohol
from others be labelled with their exact methods depend on starting with a known
or water). Doing a simple calculation can
weight. quantity of material. One common process
then identify how much material is in each
is to take a known quantity of powder, say
3) Never measure in a hurry. Individual volume of liquid. A small volume of liquid
one gram of MDMA, and divide it into ten
doses can be measured ahead of time to is much easier to accurately measure than a
equal piles, theoretically resulting in ten
remove the possibility of being rushed. tiny mass of a powder.1
100 mg doses. But if the original one gram
4) Never measure when high or overtired. measurement cant be verified, any dividing The concern that measuring out individual
When judgement is altered, its easy to process is merely guesswork. While it might doses and clearly labelling them could reduce
get more than you bargained for. seem unlikely that someone selling MDMA
will accidentally provide too much material,
While high-quality accurate scales can be
its not at all unheard of. We have received I To o k O n e
expensive, some groups choose to purchase
many reports from individuals who have
a single scale to be shared. Ten people
ordered a research chemical online only to While bored at a party, my ears perked
contributing $40 each can purchase a good
discover, when the material arrives, that up a bit at the sound of a nearby con-
scale.
the company sent nearly twice what was versation about psychoactive drugs.
ordered. Wandering closer, I overheard a girl
Eyeballing talking about an unpleasant experience
Substances that have very low dosages, she had recently had with a research
Many people who acquire powdered such as 5-MeO-DMT or 5-MeO-AMT, are chemical. I asked the first question that
psychoactives believe that they can eyeball especially dangerous to eyeball. Basing a came to mind in such a situation:
doses accurately enough that a scale isnt 5 mg dose on the fluffy crystal from last
required. How much did you take?
spring could easily lead to a 10 mg overdose
Eyeballing methods take a variety of of a new denser powder. Her answer was, One.
forms. One example is the graph paper One what? I asked. Do you know
method, where a known quantity is spread as how many milligrams?
Measurement Techniques
evenly as possible on graph paper to determine
There are several techniques people To which she replied Milligrams? I
its volume (size). Doses are measured based
use for measuring, labelling, and storing took one.
on how many graph paper squares they cover.
The problem with this inaccurate method individual doses. She didnt seem to understand that a
and with most eyeballing methodsis that unit of weight could be applied to the
1) Measuring a series of equal-weight quantity of a drug, or that just because
the volume of a measured mass (weight) of
doses. Each dose goes into its own capsule a substance came in pill or capsule
material can vary dramatically depending on
and the capsules are kept together, with a form didnt mean she had no control
how dense the material is.
label indicating the contents and quantity. over her dose.
A solid crystal of mescaline exactly The obvious problem with this method is that An Erowid Volunteer
1 cm by 1 cm will weigh significantly more if a single capsule gets separated from the

18 Erowid Extracts No. 5 / November 2003


Substance Threshold Common
Name Dose Range Dose Range
LSD 10-20 g 50-150 g [.05-.15 mg]
Fentanyl 50-100 g 200-400 g
Alprazolam 150-200 g 250-2500 g
DOB 200-300 g 750-2500 g
Flunitrazepam 250-500 g 500 g-2 mg

Threshold and Common Dose Chart (Oral)


5-MeO-AMT 500 g-2 mg 2-10 mg
privacy or increase vulnerability to law DOM 500 g-2 mg 5-8 mg
enforcement is an important one. However,
Diazepam 1-2 mg 2-20 mg
leaving things unlabeled and unmeasured
bears its own set of perils. Erring on the Nicotine 1-2 mg 3-10 mg
side of caution with measuring and labelling PCP 1-3 mg 5-10 mg
may reduce anxiety-causing guesswork
(did I take the dose I intended to take?) Psilocybin 2-4 mg 10-30 mg
and possibly dangerous mistakes. THC 2-5 mg 5-20 mg
References 5-MeO-DIPT 3-5 mg 7-20 mg
1. Zam. Liquid Measurement Technique.
Erowid.org. erowid.org/extracts/n5/ Amphetamines 3-5 mg 5-20 mg
measuring.shtml Methamphetamine 3-5 mg 5-30 mg
Hydrocodone 3-5 mg 10-30 mg
Oxycodone 3-5 mg 10-30 mg

Comparing Dosages 2C-B 3-5 mg 10-40 mg


These days, its relatively easy to find dosages 4-Acetoxy-DiPT 4-6 mg 15-30 mg
for most recreationally used psychoactives. This
wasnt true ten years ago before the 'net made the 2C-T-7 4-6 mg 15-45 mg
dissemination of information so much easier. 4-Methylaminorex 5-7 mg 10-25 mg
Individual dosages for psychoactives range Ephedrine 5-10 mg 15-60 mg
from tiny microgram quantities to more than a
gram per dose, a difference of nearly 20,000 AMT 5-10 mg 20-50 mg
times. One of the more interesting things about
Fluoxetine 5-10 mg 20-80 mg
working on the Erowid project is occasionally
getting birds-eye views of the dataset as new Morphine 8-10 mg 10-30 mg
information accumulates and fills in the terrain.
Sildenafil 10-15 mg 25-100 mg
We are suckers for data collection, indexing,
and distilling. Charts like this are mostly for fun: Caffeine 10-20 mg 30-200 mg
a snapshot to give a sense of the range, similari- MDMA 20-30 mg 75-150 mg
ties, and differences on this one measurement of
these chemicals. Bupropion 25-50 mg 75-150 mg

Notes Ibogaine 25-50 mg 200-1750 mg


All dosages listed are for oral ingestion in Modafinil 25-75 mg 100-300 mg
adults without tolerance. Quantities represent
single doses; redosing regimens (common with DXM 30-50 mg 200-400 mg
shorter-acting psychoactives) are not addressed. BZP 40-50 mg 70-150 mg
Doses are given for the most commonly found
form of each substancevariations occur with Ketamine 40-50 mg 75-300 mg
salts and isomers. Numbers are listed in ranges
DPT 60-80 mg 150-250 mg
intended to represent dose variability based on
weight, gender, sensitivity, and preferred effects Mescaline 80-150 mg 200-800 mg
level. All numbers are approximations for
comparison purposes and should not be used as Carisoprodol 100-150 mg 200-800 mg
a guide to selecting dosages for actual ingestion. Adrafinil 150-250 mg 300-600 mg
There are much more detailed numbers easily
available. GHB 400-500 mg 1000-2500 mg

Erowid Extracts No. 5 / November 2003 19


The LSD Experience
A Collection of Excerpts
An Unexpected Twist, by Strazi
Reading personal reports can be one of the best ways to Time became an enemy to us and we found that
try to understand the effects of a substance. But the fact that when we walked to the gas station to get cigarettes, we
peoples reactions to psychoactives vary considerably based found no problem in stopping in the middle of our walk,
on personality, mood, set and setting means that each report sitting down on the sidewalk and discussing life. Why
represents just one possible reaction among infinite possible did we always feel like we had to be somewhere when
experiences. The following excerpts are from reports, we didnt. We decided this was something we needed
submitted to Erowid between 2001 and 2003, that describe to permanently change about ourselves.
the LSD experience.
Erowid.org/experiences/exp.php?id=9980
Photo Credits
LSD blotter images were submitted by Monkey, Apothecary,
and L. Vijfentwintig, clockwise from center top.
Making the Most of It, by Clearlight
A common theme was that at the beginning of
Intruding on Gods Turf, by Jesse each vision, fear tempted me to go no further, but if
I saw the truth for myself, it was liberating, bringing
I was on Gods turf. Everything I sawthe millions of
in more light, allowing me to sense a higher Love. At
eyes I kept seeing and couldnt get out of my head. Were
each turn the viewer can bail out and return to normal
they the eyes of the dead and every soul that is no longer a
thought by taking the bait. In the beginning, the bait
part of humanity? Those that are lost but still manifested
is fear (dont look at this next thing or something bad
in reality on another plane? It was like looking upon
will happen) later the bait is an egotistical excitement
thousands of disassociated souls. I
(Wow!I am finally seeing
think God might have decided to show
the Truth, Me, Me, I, etc.). To
me things that night. I wasnt ready
maintain the states one must
for it. I took it upon myself and took Still Dancing, by Ted not take the bait and instead
all those doses and God said, Here
And right then I knew. I knew that EVERYTHING is focus on what Is.
you go, here is a taste of what youve an illusion. Fleeting, temporary I knew that existential-
been craving. Now that I took it upon ism is the most beautiful philosophy in the history of the The most compelling part
myselfwith such ARROGANCE world, because it's the only philosophy that captures how of this experience, and the part
to invade into matters that I was brief and fragile we are, and thus expresses how truly that has had the longest-lasting
not supposed to tune into, it was my unique our existence is. I understood in that instant that and most important impact on
time to pay. All the evil and scary "The Afterlife" is an oxymoron, fools gold. my life, was a direct result of
images that I saw, that was me toying inner stillness. Lying on my
with Gods universe. I wasnt meant The Universe is an eternitys worth of Now, that
mat, letting IT take me over,
to be able to comprehend all this, never-ending IS. I saw that our individual lives are
I was taken into hell-realms.
thats why I cant come to these an interpretive dance, expressing from our subjective
perspective what G-d, the Universe and Everything, is Im sure many of you know
thoughts naturallywithout LSD. of what I speak. The most
all about. I felt that the only way to truly have lived for
God allowed it to happen though. He excruciating physical pain
that instant is to get up on stage and feel the music
saw my soul screaming for so long combined with utter terror so
and then he decided that He thought So thats it. And here I am now, nine years later. Still that it seems like I was being
it was OK for me to see some of his dancing. psychologically gang-raped by
ballpark. It made me feel humble as a Erowid.org/experiences/exp.php?id=24938 demons while insects devoured
human being. I wasnt supposed to be me from the inside out.
herein the manifestation of my acid Instead of squirming in the
experience. It made me feel sorry for face of this horror, however,
intruding on Gods space, like I just my inner stance was one of
took things in my own hands and I really wasnt supposed stillness. To approximate this posture with words:
to. I wasnt even really sure how much I believed in God okwhats next?
before this but it solidified things so greatly now. It was
the spiritual moment of my life. Well, what was next could still have been termed
as very uncomfortable, but everything went up a notch.
Erowid.org/experiences/exp.php?id=10440 By up I mean from the fear end of the spectrum towards

20 Erowid Extracts No. 5 / November 2003


Be Careful, by Recovering
When I snapped out of it I was in a huge line of
people in a whirl-like pattern. Everyone was walking
towards the center of it, towards a black hole, with
mindless looks on their faces; and I knew it was the souls
of everyone on Earth here, shoulder to shoulder, line after Beyond Eye, by Peace and Fro
line. When the people got to the center and stepped into It was at this point that I regained my
the hole they would fall out of the hole at the end of the connection with my eyes, I suppose, and I
line and start the walk again! I remember stepping right started to create evil, blackened images around
up to the hole, then getting a notion of what was happening the room. Even though I was sliding off the
and freaking out! I pushed my way through about 5 of timeless merry-go-round LSD provides, I was
these mindless people before the system got me again still aware of intense visual distortion. My vision
then suddenly felt as if it were splintering into a
and I had to resume walking with no choice; but I was
numberless amount of different dimensions, or
out of place in line, and in return, I knew I had lost my
states of consciousness.
place in life.
Then, like a picture forming, my immediate
Erowid.org/experiences/exp.php?id=18029
view began to transmogrify into a thousand
interlacing eyes peering intently with their
piercing pupils upon my retarded, simplistic
insignificant self. At this I stood and
love. I was still in pain and scared but it eased up staredwith glazed eyes as my mate informed
somewhat, so at least I felt a little gratitude for that. me latertrying to comprehend the meaning
But instead of thinking about it too much or looking behind such a depiction whilst I felt a flurry of
for something to cling to or something to save me, I emotion engulf my soul, from interest to apathy,
maintained. okwhats next? curiosity to fear, as if each had no reasoning
It got better (to use a dualistic word), but still I did nor meaning behind, just a different aspect of
not move internally: okwhats next? Gradually, the constant motion. At fear, unfortunately, I lost
feelings moved up, up, up the spectrum, all the while, myself and all that it entails followed. As fear
I remain a rock. Before my naked eye was laid as if in is one of the most integral, primal emotions or
pages of a book what seemed on the order of 10,000 reaction that any intelligible being possesses, its
different thought-emotional states. These ranged from easy to lose ones self to such. And when it is
the lowest fear up to the highest joy, and they came a result of some vision or something that is not
in order. At the end it felt as though bubblenergy an immediate threat to mortality, like the fear of
was expanding through every cell in my body (much death or whatever, flowing emotion is rendered
better than the disco-biscuits of old). Everything was perishable or susceptible to all things ill.
perfect and I had once again If all that shit made
reached harmony with All sense to you, the reader,
That Is. Still I did not move. then you can understand
okwhats next? Umpsquamadic Peels, by Hiab-x how I was frozen, lying
What was next is Back on the street I had staggered a few more paces then fallen. I on the floor with my left
obscured from my current was now a seven year old child lying on the pavement, my best friends eye folding into my right,
human vision. I can comment parents stood over me feeling concerned What happened, Hes hit his cross-eyed, perplexed,
however on the lessons that head, Call an ambulance. A disk shaped hole appeared above me with rendered utterly useless.
that final moment imprinted someones arm reaching down to me to try and pull me up into safety; I Eventually I guess I
on me. Everything is love tried to reach the grasping hand but couldnt, then the hole disappeared. passed out or something,
and fear. But since fear is I was staggering along the street again at the bottom of the cul-de-sac. but I woke the next day
a lower form of love, then feeling so fucked up I
My gaze lifted to the sky and the skys gaze fell upon me. Each cloud
everything is love. God is found it hard to think.
was now a giant amoeba-type organism, covered in dots which pulsed in
love. everything is god. One I had an overwhelming
colour like the skin of a cuttlefish; each giant amoeba had a giant blue
cannot point at something that feeling that I had done
human-looking eye observing me. I could hear voices taunting me, telling
is not part of god. God/devil, myself some permanent
me I was stupid, telling me how thick I was for looking for the answers,
love/fear are only creations of damage, which will
telling me I had spastic consciousness.
our limited thought-state. In perpetually reside in
the world beyond our dualistic Erowid.org/experiences/exp.php?id=15901 my subconsciousin
logic, everything is what it is. other words, not easy to
Everything is everything. explain.
Erowid.org/experiences/exp.php?id=25635 Erowid.org/experiences/exp.php?id=26596

Erowid Extracts No. 5 / November 2003 21


E SCOTTO
SCOTTOLOGY
LOGY
Addicted to Everything
By Scott O. Moore

A friend asked me recently why I liked alcohol so much. What plainable, and stresses freedom of choice and responsibility for the
did I get from alcohol that made being drunk such a regular pursuit? consequences of ones acts. I extract joy and pleasure from reality
My initial response took the form of a kind of idealized alcohol in whatever manner works to help me survive the world, keeping in
trip report: I greatly enjoy the relaxing disinhibition that alcohol mind strict personal guidelines about not harming others. Drugs and
can bring, the relative reliability of the alcohol experience, the easy alcohol are an important part of that formula. Theres a richness to
availability of alcohol in quantity. Unlike marijuanaa drug I dont the constant seesaw between sobriety and intoxication that drives me,
enjoyI find that alcohol leaves me with more of my general wits one that defies authoritarian notions of propriety and restraint.
about me during a greater percentage of the experience, while still
Alcohol, of course, extracts a darker toll from me than psychedel-
being inebriating enough to satisfy me. Alcohol just seems suited to
ics. I lose my temper more frequently now, embarrass myself more
my general temperament.
often now, and perhaps most disturbingly, lose chunks of time from
Of course, my relationship to alcohol is more complicated than memory much more than I would prefer. I can try to moderate these
that. I was essentially straight edge all through high school, then incidents, but my appetite has difficulty moderating dosage. I know
became a bit of a binge drinker in college. After getting turned on that alcohol is physiologically disastrous at these levels. In fact, my
to LSD, I went through a short period of viewing alcohol (and all friend initiated this conversation with me in part because his wife had
non-psychedelic recreational substances) with a haughty disdain, observed me completely obliterated at parties recently with what she
before realizing that I enjoyed alcohol too much to keep up such perceived to be an alarming frequency. I cant deny any of it. I can
an attitude. Still, it wasnt until my year without psychedelicsa rationalize, try to stay alert, and hope to work within drunken confines
year that coincided with an especially brutal time in my professional to change myself, but hope is a cheap word in a situation like this.
lifethat alcohol really took on a prominent role in my life.
But theres something I enjoy perhaps too much in the wild
Now I drink pretty much every evening, a pattern interrupted abandonment that intoxication provides. Its a grim kind of
only by occasional use of psychedelics or other drugs, and even then celebration, a dance on razors edge, which seems an appropriate
alcohol is almost always a part of my coming down ritual. I self- expression of my personality. The fact is that I do enjoy the experience
identify as an alcoholic, both to myself and to my friends, to help me of lifeof being in love, of being an artist, of being drunk and high.
stay cognizant of just how much I drink and the fact that my life has Another friend sent me a quote from Baudelaire that expresses my
taken this turn. I tell myself that Im not a self-destructive alcoholic; feelings better than I ever thought to:
I hold down jobs, I stay active in theatre and music and writing, I
One must be forever drunken: that is the sole question of
practice aikido twice a week, I stay involved in my community, I have
importance. If you would not feel the horrible burden of Time
a healthy marriage. I contrast this with the only other alcoholic Ive
that bruises your shoulders and bends you to the earth, you
ever known, the stepfather who raised me until I was eleven and who
must be drunken without cease. But how? With wine, with
destroyed his marriage and his career by drinking too much. But
poetry, with virtue, with what you please. But be drunken. And
thats a rationalization. By any reasonable definition of alcoholism,
if sometimes, on the steps of a palace, on the green grass by
I likely qualify. Drinks every daycheck. Drinks alonecheck.
a moat, or in the dull loneliness of your chamber, you should
Drinks to get hammeredcheck.
waken up, your intoxication already lessened or gone, ask of
Still, the conversation didnt stop there, because alcoholism is the wind, of the wave, of the star, of the bird, of the timepiece;
an incomplete description of what motivates me. Im certainly an ask of all that flees, all that sighs, all that revolves, all that
addict, but not simply to alcoholIm addicted to altered states of sings, all that speaks, ask of these the hour; and wind and
consciousness in general. Im addicted to being off baseline. Im wave and star and bird and timepiece will answer you: It is
addicted to the kind of recreational drug use that respected members the hour to be drunken! Lest you be the martyred slaves of
of the psychedelic movement look upon with disdain, and I dont Time, intoxicate yourselves, be drunken without cease! With
particularly care. This appetite is comprised of equal, and somewhat wine, with poetry, with virtue, or with what you will.
contradictory, parts hedonism and escapism. Drug use in my life
Of course, after years of drug and alcohol use, Baudelaire
is a way to make the world feel better, while at the same time an
died at the age of forty-six after suffering a stroke of aphasia and
attempt to distance me from the world. Psychedelics offer additional
hemiplegia. I refuse to draw the obvious conclusion, mostly for
psychological benefits, but psychedelic-inspired insight and revelation
are happy surprises, not a goal.
aesthetic reasons.
Erowid.org/columns/scotto/
I do study with fascination and respect how others in the world
incorporate psychedelic use into a spiritual path, but thats not the road
1. Baudelaires Death: In 1862 a minor stroke or some other sudden sign
Im on. I long considered myself a nihilist before recently coming to of deteriorating health gave him a warning of the consequences of
the conclusion that maybe Im too happy-go-lucky for that; perhaps alcohol, opium, and hashish. The remaining years of Baudelaires life
Im more of an existentialist, someone who, as Dictionary.com offers, were darkened by despair and financial difficulties. He died in a Paris
emphasizes the uniqueness and isolation of the individual experience clinic of aphasia and hemiplegia on August 31, 1867, in his mothers arms.
(Liukkonen P, Biography of Charles Baudelaire. PoetryConnection.net)
in a hostile or indifferent universe, regards human existence as unex-

22 Erowid Extracts No. 5 / November 2003


THE DISTILLATION
Aside from the daily maintenance and upkeep of the site, we Fundraising
are always working on a variety of projects. Many of these involve We continue to struggle with our reluctance to spend time doing
updating existing sections of the site as a part of the overall Erowid fundraising instead of working on the site. As we re-examined our
3.0 project. Below is a list of updates and notes about some of these fundraising model this year, it became clear we need to expand our
projects. base of support. Although major funders are critical to our continued
work, the blow of losing one of those funders endangers the project.
EcstasyData.org We would like to reach a point where the Erowid membership provides
The EcstasyData project has tested 72 tablets since enacting a enough support to cover the basic costs of running the site.
required $20 co-pay in May 2003. With this co-pay we were able
Our two primary goals for this year were to increase general
to stretch the remaining funds for a few extra months, but we have
memberships and increase the percentage of Fellow level ($200+)
now reached the end of the projects budget. We still believe that this
and higher donations. We began the year with about 450 members and,
project is a valuable one, but until additional funding can be found,
with a series of fundraisers and membership drives, have now increased
we will no longer be accepting tablets for testing. Serious suggestions
to over 750 members. In previous years, we only had a handful of
for funding sources in the $20-40,000 range should be forwarded to
people donate $200 or more, suggesting we needed to work to fill in
admin@ecstasydata.org.
the gap between general membership and large grants ($5,000 and
higher). This year we more than doubled the number of Fellow level
E CSTASY D ATA S TATISTICS donations. We intend to continue trying to increase memberships over
the next year and hopefully reach 1500 by the end of 2004.
2003

Daily Visitors 1,425 Daily Page Hits 9,091


Weve had a lot of help with our recent fundraising efforts. Two
Daily File Hits 170,783 Tablets Tested 142 different groups (one in Seattle and one in Chicago) have held events
to help raise funds. Scott O. Moore published a book of short stories
Tablets Tested Testing Results (1999-2003)
that he is selling as an Erowid fundraiser, and Sasha Shulgin, Ann
2003 142 Total Tablets Tested 1210 Shulgin and Wendy Perry have signed copies of their books for us
2002 301 MDMA Only (42%) 507 to give as Fellow level membership gifts.
2001 332 MDMA + Something (13%) 158
2000 333 No MDMA (45%) 545
If you have an idea for fundraising, wed love to hear from you.
1999 69 - Nothing 89
Art Vaults
The Art Vaults are currently in the process of being reorganized.
When this area of the site was started three years ago, we didnt
Spirit & Freedom Vaults expect the level of interest that it has drawn. It has become apparent
The Spirit Vaults and Freedom Vaults are currently where were over the past year that the existing structure is not sufficient to hold
beta-testing some of the Erowid 3.0 front-end (see page 4). They the wide variety of submissions we receive. The new structure will
have also seen the first major reorganization and editing in almost be oriented towards a wider range of art and ability levels. The first
five years. We continue to seek volunteer curators to help improve step of this reorganization will hopefully be completed over the next
and maintain these vaults. few months.

Volunteers
Thank you to both the short-term and long-term volunteers who
do the work of link checking, experience report reviewing, document S ITE S TATISTICS
CURRENT

translating, error correcting, and art processing, as well as those who


Content Pages 22,936 Daily Visitors 28,153
act as expert resources for the Erowid crew. Two notification lists have
Archived Images 4,461 Daily Page Hits 376,844
been created to communicate with potential volunteersthe volunteers
list and the content review listboth of which receive minimal traffic. Current Members 751 Daily File Hits 1,539,208
As always, we welcome sincere inquiries and encourage self-motivated Avg Daily Avg Daily Avg Daily
volunteers to read our About Volunteers pages. File Hits Page Hits Visitors
BY MONTH

Sep 2003 1,419,346 351,628 26,888


References Au g 2003 1,242,013 306,921 23,143
We continue to collaborate with MAPS on collecting scientific Jul 2003 1,225,892 308,748 23,823
references about MDMA, psychedelics, and related topics. Over Jun 2003 1,350,403 324,441 25,002
the summer, we made progress towards a revision of the system May 2003 1,477,751 343,524 26,391
that would allow us to offer this software for use by other sites.
2003 1,401,006 344,066 25,880
We are currently seeking a dedicated volunteer to be in charge
BY YEAR

2002 1,206,855 283,541 23,042


of the References Vaults. The References Manager would need
2001 798,400 207,427 17,300
experience reading scientific literature and interest in following
research news, searching PubMed for new references, and adding 2000 462,000 126,000 12,000
these to a database. 1999 135,800 37,000 4,100

Erowid Extracts No. 5 / November 2003 23


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First they laugh at you; then they The dancer of the future will be one Drug use, some might say, is
ignore you; then they fight you and whose body and soul have grown destroying this country. And we
then you win. so harmoniously together that the have laws against selling drugs,
Mahatma Gandhi (18691948) natural language of that soul will have pushing drugs, using drugs,
become the movement of the body. importing drugs. And the laws
The people never give up Isadora Duncan (18771927) are good because we know what
their liberties but under some happens to people in societies
delusion. Nature provides exceptions to and neighborhoods which
Edmund Burke (17291797) every rule. become consumed by them. And
so if people are violating the law
Margaret Fuller (18101850)
by doing drugs, they ought to be
Truth comes out of error more
accused and they ought to be
easily than out of confusion. Intolerance of ambiguity is the mark
convicted and they ought to be
Francis Bacon (15611626) of an authoritarian personality.
sent up.
Theodor W. Adorno (19031969)
Rush Limbaugh (b. 1951), in 1995.
There are two kinds of people, Limbaugh recently admitted
those who do the work and those his dependence on illegally
who take the credit. Try to be purchased opiates.
in the first groupthere is less
competition. Quod ali cibus Normal is in the eye of the
Indira Ghandi (19171984) beholder.

To know is nothing at all; to


est aliis fuat Whoopi Goldberg (b.1949)

imagine is everything.
Anatole France (18441924) acre venenum We are going to have peace even
if we have to fight for it.
Dwight D. Eisenhower
Id rather be a failure at something [ What is food to one man may (18901969)
I love than a success at something
I hate.
be fierce poison to others ]
How far you go in life depends on
George Burns (18961996) your being tender with the young,
Lucretius (c. 9955 B.C.E.)
compassionate with the aged,
Penalties against possession of a sympathetic with the striving, and
drug should not be more damaging tolerant of the weak and strong.
to an individual that the use of the Giving money and power to Because someday in your life you
drug itself. government is like giving whiskey will have been all of these.
President Jimmy Carter, (b. 1924), and car keys to teenage boys. George Washington Carver
in a 1977 speech before Congress. P.J. ORourke (b. 1947) (18601943)
in Parliament of Whores, 1991
Study as if you were going to live It is difficult to live without opium
forever; live as if you were going Nobody realizes that some people after having known it because it is
to die tomorrow. expend tremendous energy merely difficult, after knowing opium, to
Maria Mitchell (18181889) to be normal. take earth seriously. And unless
Albert Camus (19131960) one is a saint, it is difficult to live
Pursuing the religious life today without taking earth seriously.
without using psychedelics drugs If we were to read about spiritual Jean Cocteau (18891963)
is like studying astronomy with the things, it is only wordswhat is of
naked eye because thats how they greatest importance is that we have If they can get you asking the
did it in the first century A.D. experience. Not words, not beliefs, wrong questions, they dont have
Timothy Leary, (19201996) but experience. to worry about the answers.
in The Politics of Ecstasy, 1968 Dr. Albert Hofmann (b. 1906) Thomas Pynchon (b. 1937)

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