Material Safety Data Sheet

Manufacturer: ERBA diagnostics Mannheim GmbH

Mallaustrasse 69 73
68219 Mannheim / Germany

phone +49 621 87 99 770

fax. +49 621 87 99 688

Date of card issue: 03.02.2004

Date of card update: 01.07.2011
1. Identification of the preparation.

SP Kit-UREA
5 x 44 ml + 5 x 11 ml (catalogue No XSYS020)

The SP Kits - UREA consist of components: 1-UREA (1-REAGENT) and 2-UREA (2-REAGENT). It
is designed for laboratories in hospitals and outpatient clinics. The set is used for
determination of urea concentration in serum or plasma, urine.

2. Hazards Identification.

Classification of the mixture:

The preparation is not regarded as dangerous.

Label elements:

None

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Identification number: MSDS/UREA
Updating no: 04
Number of pages: 4
3. Composition / information on components.
1-REAGENT
Substance Content CAS number EC number Classification according to Act
name (% of No. 356/2003
weight) Classification according to (EC)
No. 1272/2008
Sodium azide < 0,05% 26628-22-8 247-852-1; T+; N; R 28-32-50/53; S 28-45-60-61
Acute Tox. 1, Aquatic Acute 1,
Aquatic Chronic 1; H300, H400,
H410; P273, P501, EUH032
Chelaton III, p.a < 0,03 % 6381-92-6 205-358-3 Xn; R 22-36/37/38; S 2-26-36-46
Acute Tox. 4, Skin Irrit. 2, Eye Irrit. 2
STOT SE 3; H302, H315, H319,
H335; P261, P280,
P305+P351+P338, P321, P405,
P501
Tris puriss < 0,01 % 77-86-1 201-064-4 Xi; R 36/37/38 S:26-36
Skin Irrit. 2, Eye Irrit. 2 STOT SE 3;
H315 H319, H335; P261,
P305+P351+P338,
-ketoglutaric < 0,15 % 328-50-7 206-330-3 Xi; R 37/38-41 S: 26-39
acid Skin Irrit. 2, Eye Irrit. 1 STOT SE 3;
H315 H318, H335; P261, P280,
P305+P351+P338,

2-REAGENT
Substance Content CAS number EC number Classification according to Act
name (% of No. 356/2003
weight) Classification according to (EC)
No. 1272/2008
Sodium azide < 0,1% 26628-22-8 247-852-1; T+; N; R 28-32-50/53; S 28-45-60-61
Acute Tox. 1, Aquatic Acute 1,
Aquatic Chronic 1; H300, H400,
H410; P273, P501, EUH032
Sodium < 0,09 % 497-19-8 207-838-8 Xi; R 36; S 22-36
carbonate Eye Irrit. 2; H319; P305+P351+P338,
The full text of each relevant R and H phrases and S and P phrases see in Section 16.

4. First-Aid Measures.

Description of first aid measures

General advice - Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled - If breathed in, move person into fresh air.
In case of skin contact - wash off with large amount of water. Take off the contaminated clothing.
In case of eye contact - rinse with large amount of water.
If swallowed - give the sufferer a large amount of water to drink. Evoke vomiting. Administer activated
charcoal.

Most important symptoms and effects, both acute and delayed

no data available

Indication of immediate medical attention and special treatment needed

no data available

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5. Fire Fighting Measures:

Extinguishing media

Suitable
The preparation is not a flammable substance. In adaptation to materials stored in the immediate
neighbourhood.
Unsuitable extinguishing media
Not known.
Special hazards arising from the substance or mixture
None known.
Precautions for fire-fighters
According to the existing fire-fighting regulations.

6. Accidental Release Measures:

Personal precautions, protective equipment and emergency procedures

Avoid contamination with the preparation.
Environmental precautions
Do not discharge into the drains, surface waters, and groundwater.
Methods and materials for containment and cleaning up
Collect small quantities with the use of an absorbing agent, rinse with large amount of water if
necessary.

7. Handling and Storage:

Precautions for safe handling

In accordance with the norms generally accepted for chemicals in laboratories.
Conditions for safe storage, including any incompatibilities
Hermetically closed. In temperature from +2oC do +8oC.
Specific end uses
no data available

8. Exposure Controls/ Personal Protection:

Appropriate control parameter:

See Polish regulations.
Sodium azide: NDS 0,1 mg/m3, NDSCh 0,3 mg/m3. Risk of skin absorption.
Exposure controls
Appropriate engineering controls
Avoid prolonged contact with skin and eye, swallowing the product. Ensure washing facilities (warm
water) after working hours and before breaks. Was thoroughly hands after using the product.

Personal protective equipment

Eye/face protection: Safety goggles
Respiratory protection: not required with adequate ventilation, otherwise breathing apparatus.
Skin protection: required (Handle with gloves)
Body Protection: required (Complete suit protecting against chemicals)

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9. Physical and Chemical Properties.
Appearance:
Odour (aroma):
Odour Threshold:
pH:
Melting/freezing point:
Initial boiling point and
boiling range:
Flash point:
Evaporation rate:
Flammability (solid, gas):
Upper/lower
flammability or
explosive limits:
Vapour pressure:
Vapour density:
Relative density:
Water solubility:
Partition coefficient
noctanol/water:
Autoignition temperature:
Decomposition temperature:
Viscosity:
Explosive properties:
Oxidizing properties:
1-UREA; 1-REAGENT
clear colourless solution
odourless
no data available
7,8 (25 0C)
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
2-UREA; 2-REAGENT
clear colourless solution
odourless
no data available
10,0 (25 0C)
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available
no data available

10. Stability and Reactivity:

Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
The preparation is stable in conditions provided by the manufacturer.
Incompatible materials
Heavy metals, metal salts, acids.
Hazardous decomposition products
In the case of fire nitrose gases.

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11. Toxicological Information:
Acute toxicity
Human oral LD50 (g.kg-1)......................................not applicable
Rat oral LD50 (mg.kg-1).........................................27 (sodium azide)
Rabbit dermal LD50 (mg.kg-1)...............................20 (sodium azide)
Rat inhalation LD50 (g.kg-1)..................................not applicable
Rat inhalation TLS (g.kg-1)..................................not applicable
Irritant
Not applicable.
Corrosion
Not applicable.
Sensitization
No data available.
Toxicity on repeated exposure
No data available.
Carcinogenicity
No data available.
Mutagenity
No data available.
Reproductive toxicity
Not available.

Further data:
The product should be handled with the care usual when dealing with chemicals.

12. Ecological Information:

Ecotoxicity
LC50 96 hrs, fish (Lepomis macrochirus) (mg.l-1)...............................0,7 (Sodium azide)
EC50 48 hrs, daphnia pulex (mg.l-1) ..................................................4,2 (Sodium azide)
IC50 72 hrs algae (mg.l-1)...................................................................272 (Sodium azide)
CHSK...............................................................................................not applicable
BSK5.................................................................................................not applicable
Persistence and degradability
Not applicable.
Bioaccumulative potential
Not applicable.
Mobility in soil
Not applicable.
Results of PBT and vPvB assessment
Not applicable.
Other adverse effects
Not applicable.

Further ecological data:

Ecological problems should not be expected if you use and apply the product appropriately.

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13. Disposal Considerations:
Product:
Chemical residues, in general, are included into special waste. Disposing of the latter is regulated by
appropriate laws and ordinances. We recommend contacting the appropriate authorities, or waste
disposal enterprises that will advise you on how to dispose of special waste.

Contaminated packaging
Remove in accordance with official regulations. Treat contaminated packages in the same way as the
substance itself. If the regulations do not provide otherwise, non-contaminated packages can be treated
like household waste or forward them to be utilized.

14. Transportation Information:

The product is not subject to transport regulations.

15. Regulatory Information:

Material Safety Data Sheet was prepared in accordance with:

The EC Directive Nr UE2001/58/WE, the EC Directive Nr 1999/45/EG, the EC Directive 67/548 EEC,
the EC Directive No. 1907/2006 (Dangerous Product Regulations incl. EC Guidelines).

Chemical Safety Assessment

no data available

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15. Other Information.

List of R-phrases:
R 22 Harmful if swallowed.
R 28 Very toxic if swallowed.
R 32 Contact with acids liberates very toxic gas.
R 36 Irritating to eyes.
R 37/38 Irritating to respiratory system and skin.
R 36/37/38 Irritating to eyes, respiratory system and skin.
R 41 Risk of serious damage to eyes.
R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment
List of H-phrases:
H400 Very toxic to aquatic life.
H300 Fatal if swallowed.
H410 Very toxic to aquatic life with long lasting effects.
H319 Causes serious eye irritation.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H335 May cause respiratory irritation
H302 Harmful if swallowed.
List of P-phrases:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see on this label)
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing.
List of S-phrases:
S 28 After contact with skin, wash immediately with plenty of soap and water.
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
S 60 This material and its container must be disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to special instructions/ Safety data sheets.
S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 Wear suitable protective clothing.
S 2 Keep out of the reach of children.
S 46 If swallowed, seek medical advice immediately and show this container or label.
S 39 Wear eye/face protection.
S 22 Do not breathe dust.

The foregoing information is based on the present state of our knowledge. It characterizes the product
with respect to the appropriate safety measures. They do not guarantee the properties of the product.

We do not take responsibility for damage and losses that may result from inappropriate use of the
preparation.

Reason of changes: change in legislation.

General updating.

The foregoing safety chart prepared in electronic version is legally valid without sign manual.

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