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TH EDITION
PHARMACOTHERAPY
A PAT H O P H YS I O LO G I C A P P R O AC H
PHARMACOTHERAPY
A PAT H O P H YS I O LO G I C A P P R O AC H
1 2 3 4 5 6 7 8 9 0 DOW/DOW 18 17 16 15 14
ISBN 978-0-07-180053-2
MHID 0-07-180053-0
And finally to our families for the time that they have
sacrificed so that this ninth edition would become a reality.
Pharmacotherapy:
A Pathophysiologic Approach,
Ninth Edition
KEY FEATURES
Goes beyond drug indications and doses to include drug selection, administration, and monitoring
Enriched by more than 300 expert contributors
Revised and updated to reect the latest evidence-based information and recommendations
Includes valuable learning aids such Key Concepts at the beginning of each chapter, Clinical
Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes
that examine the complicated issues faced by students and clinicians in providing drug therapy
28
appears in most sections
Acute Kidney Injury All diagnostic ow diagrams, treatment
William Dager and Jenana Halilovic
4
structural damage within the kidney, and (c) postrenalan
obstruction is present within the urine collection system.
Conventional formulas used to determine estimated
glomerular ltration rate (eGFR) and creatinine clearance
and surgical history, medication use, physical examination, and
multiple laboratory tests. Management goals include maintenance
of blood pressure, fluid, and electrolyte homeostasis, all of which
New drug monitoring tables have been added
may be dramatically altered. Additional therapies designed to elimi-
should not be used to estimate renal function in patients nate or minimize the insult that precipitated AKI include discon-
6
established AKI.
Supportive management remains the primary approach to
prevent or reduce the complications associated with AKI.
Supportive therapies include renal replacement therapy
common etiologies of AKI are presented. Methods to recognize and
assess the extent of kidney function loss are also discussed. Finally,
preventive strategies for patients at risk and management approaches
for those with established AKI are reviewed.
incorporated evidence-based treatment
7
(RRT), nutritional support, avoidance of nephrotoxins, and
blood pressure and uid management.
For those patients with prolonged or severe AKI, RRT is the
DEFINITION AND CLASSIFICATION guidelines when available, include ratings
cornerstone of support along with an aggressive approach OF ACUTE KIDNEY INJURY
8
to uid, electrolyte, and waste management.
Drug dosing for AKI patients receiving continuous renal
replacement therapy (CRRT) or sustained low-eciency
1 Over the past 10 years, several efforts by a broad consensus
of experts have been made to standardize the definition and clas-
sification of AKI. In 2004, the Acute Dialysis Quality Initiative
of the level of evidence to support the key
therapeutic approaches
dialysis (SLED) is poorly characterized. Dosing regimens (ADQI) group published a consensus-derived definition and clas-
should be individualized and therapeutic drug monitoring sification system called the Risk, Injury, Failure, Loss of Kidney
utilized whenever possible. Function, and End-Stage Kidney Disease (RIFLE) classification.1
9 Diuretic resistance is a common phenomenon in the patient In 2007, a modified version of RIFLE was developed by the Acute
with AKI and can be addressed with sodium restriction, Kidney Injury Network (AKIN) and these criteria are presented
combination diuretic therapy, or a continuous infusion of a in Table 28-12 (see Table 28-1 for an overview of all classification
loop diuretic. systems). Both classification systems are now widely accepted and
have been validated to predict outcomes in thousands of patients Twenty-four online-only chapters are available
611
at www.pharmacotherapyonline.com
Key Concepts summarize
must-know information in
each chapter
CHAPTER
sympathomimetic
activity
Levobunolol Nonselective Betagan Solution 0.25, 0.5 One drop twice a day
Metipranolol Nonselective OptiPranolol Solution 0.3 One drop twice a day
Timolol Nonselective Timoptic, Solution 0.25, 0.5 One drop every dayone
Betimol, Istalol to two times a day
Glaucoma
Dipivefrin Epinephrine prodrug Propine Solution 0.1 One drop twice a day Increased aqueous humor
outow
CHAPTER
Injection 500 mg/vial 250500 mg
Diamox Capsule 500 mg 500 mg twice a day
Sequels
Osteoblast Mature Methazolamide Generic Tablet 25 mg, 50 mg 2550 mg two to three
osteoclast times a day
Prostaglandin Analogs
LRP k LRP
PTH 5/6
5/6 r
e
m
FZD
PTHrP e
Axin n
GSK-3 -catenin
Axin
GSK-3
Full-color illustrations enhance
Cytoplasm
Nucleus Target
-catenin
degradation
and clarify the text
genes
Osteoblast
C
FIGURE 732 (Continued ) B. Molecular level detail of major pathways during bone resorption steps 2 and 3, which also showcase
drug targets for approved and investigational agents. (Ca+, calcium ion; Cbl, a ubiquitin ligase; FAK, focal adhesion kinase; H+, hydrogen
ion; M-CSF, macrophage colony-stimulating factor; Mg+, magnesium ion; NCP, noncollagenous protein; NF-B, nuclear factor kappa B;
OPG, osteoprotegerin; Pl3K, phosphatidylinositol 3-kinase; Phos, phosphorus; PTH, parathyroid hormone; RANK, receptor activator
of nuclear factor-B; RANKL, receptor activator of nuclear factor-B ligand; src, tyrosine-protein kinase; TRAF-6, tumor necrosis factor
receptor associated factor 6; Trap, tartrate-resistant acid phosphate.) C. Molecular level detail of major pathways during bone formation
steps 4 and 5, which also showcase drug targets for approved and investigational agents. (BMP, bone morphogenetic protein; DKK-1,
Dickko-1; FZD, frizzled element; GSK-3, glycogen synthase kinase-3; LRP5/6, lipoprotein receptor-related protein 5 or 6; PPAR-,
peroxisome proliferator-activated receptor- ; PTH, parathyroid hormone; PTHrP, parathyroid hormone-related protein; runX2, runt-
related transcription factor; sFRP, secreted frizzled related protein; Wnt, wingless tail ligand.)
1341
CHAPTER
(patients are often brought to a physician by their curved penis when erect, decreased pulses in
partners) the pelvic region (suggesting impaired vascular
Nonadherence to medications patient believes are ow to the penis), or decreased anal sphincter
causing erectile dysfunction tone (suggesting impaired nerve function to the
Erectile Dysfunction
Signs Laboratory Tests
If completing an International Index of Erectile If the patient has signs of hypogonadism and
Dysfunction survey, results are consistent with low complains of decreased libido, a serum testosterone
satisfaction with the quality of erectile function concentration may be below the normal range,
Medical history may identify concurrent medical which would be consistent with a hormonal cause of
illnesses, past surgical procedures that interfere erectile dysfunction
with good vascular ow to the penis or damage If the patient has an enlarged prostate noted on
nerve function to the corpora, or mental disorders digital rectal examination, a blood sample for
associated with decreased reception of sexual stimuli prostate-specic antigen should be obtained. If
Medication history may reveal prescription or elevated, the patient should be evaluated for a
nonprescription medications that could cause prostate disorder, which could contribute to erectile
erectile dysfunction dysfunction
the drug therapy problems most likely encountered continued or the dose should be reduced.
A physical examination of the patient should include a check
for hypogonadism (i.e., signs of gynecomastia, small testicles, and
decreased beard or body hair). The penis should be evaluated for
TREATMENT
Erectile Dysfunction
in real-world practice. This new edition is packed diseases associated with abnormal penile curvature (e.g., Peyronies
disease), which are associated with erectile dysfunction. Femoral
and lower extremity pulses should be assessed to provide an indica-
tion of vascular supply to the genitals. Anal sphincter tone and other
Desired Outcomes
The goal of treatment is improvement in the quantity and quality of
with patient cases and makes the ideal study genital reflexes should be checked for the integrity of the nerve sup-
ply to the penis. A digital rectal examination in patients 50 years or
older is needed to rule out benign prostatic hyperplasia, which may
contribute to erectile dysfunction.
penile erections suitable for intercourse and considered satisfactory
by the patient and his partner. Simple as this may sound, healthcare
providers must ensure that patients and their partners have reason-
able expectations for any therapies that are initiated. Furthermore,
companion to the 9th edition of DiPiros Selected laboratory tests should be obtained to identify the
presence of underlying diseases that could cause erectile dysfunc-
tion. They include a fasting serum blood glucose and lipid profile.
only patients with erectile dysfunction should be treated. Patients
who have normal sexual function should not seekor be encour-
aged to seektreatment in an effort to enhance sexual function or
Visit www.mhpharmacotherapy.com
Dipi_FM_i-xxxviii.indd vii 10/24/13 12:12 PM
Dipi_FM_i-xxxviii.indd viii 10/24/13 12:12 PM
Contents
ix
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv
Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xxxiii SECTION 2 Respiratory Disorders 369
Foreword to the First Edition . . . . . . . . . . . . . . . . . . . . . . . . . . . .xxxv
Section Editor: Robert L. Talbert
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xxxvii
15. Asthma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369
H. William Kelly and Christine A. Sorkness
SECTION 1 Cardiovascular Disorders 1
16. Chronic Obstructive Pulmonary Disease . . . . . . . . . . 401
Section Editor: Robert L. Talbert Sharya V. Bourdet and Dennis M. Williams
CONTENTS
Joanna Q. Hudson and Lori D. Wazny
46. Attention Decit/Hyperactivity Disorder . . . . . . . . . . 959
30. Hemodialysis and Peritoneal Dialysis . . . . . . . . . . . . . . 665 Julie A. Dopheide and Stephen R. Pliszka
Kevin M. Sowinski, Mariann D. Churchwell, and Brian S. Decker
47. Eating Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 973
31. Drug-Induced Kidney Disease . . . . . . . . . . . . . . . . . . . . 687 Steven C. Stoner and Valerie L. Ruehter
Thomas D. Nolin
48. Substance-Related Disorders I: Overview and
32. Glomerulonephritis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705 Depressants, Stimulants, and Hallucinogens . . . . . . 985
Alan H. Lau Paul L. Doering and Robin Moorman Li
33. Drug Therapy Individualization for Patients 49. Substance-Related Disorders II: Alcohol,
with Chronic Kidney Disease . . . . . . . . . . . . . . . . . . . . . . 729 Nicotine, and Caeine . . . . . . . . . . . . . . . . . . . . . . . . . . . 1003
Rima A. Mohammad and Gary R. Matzke Paul L. Doering and Robin Moorman Li
34. Disorders of Sodium and Water Homeostasis . . . . . . 745 50. Schizophrenia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1019
Katherine Hammond Chessman and Gary R. Matzke M. Lynn Crismon, Tami R. Argo, and Peter F. Buckley
35. Disorders of Calcium and Phosphorus 51. Major Depressive Disorder . . . . . . . . . . . . . . . . . . . . . . . 1047
Homeostasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 Christian J. Teter, Judith C. Kando, and Barbara G. Wells
Amy Barton Pai
52. Bipolar Disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1067
36. Disorders of Potassium and Magnesium Shannon J. Drayton and Christine M. Pelic
Homeostasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783
Donald F. Brophy
53. Anxiety Disorders I: Generalized Anxiety, Panic,
and Social Anxiety Disorders. . . . . . . . . . . . . . . . . . . . . 1083
37. AcidBase Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797 Sarah T. Melton and Cynthia K. Kirkwood
John W. Devlin and Gary R. Matzke
54. Anxiety Disorders II: Posttraumatic Stress
Disorder and Obsessive-Compulsive Disorder . . . . 1103
Cynthia K. Kirkwood, Sarah T. Melton, and
Barbara G. Wells
SECTION 5 Neurologic Disorders 817
55. Sleep Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1115
Section Editor: Barbara G. Wells John M. Dopp and Bradley G. Phillips
38. Alzheimers Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817 56. Disorders Associated with
Patricia W. Slattum, Emily P. Peron, and Angela Massey Hill Intellectual Disabilities . . . . . . . . . . . . . . . . . . . . . . . . . . 1127
Nancy C. Brahm, Jerry R. McKee, and Douglas W. Stewart
39. Multiple Sclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 835
Jacquelyn L. Bainbridge, Augusto Miravalle,
and John R. Corboy
88. Skin and Soft-Tissue Infections . . . . . . . . . . . . . . . . . . . 1743 107. Colorectal Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2159
Douglas N. Fish and Susan L. Pendland Lisa E. Davis, Weijing Sun, and Patrick J. Medina
CONTENTS
90. Tuberculosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1787 109. Lymphomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2209
Rocsanna Namdar, Michael Lauzardo, and Alexandre Chan and Gary C. Yee
Charles A. Peloquin
110. Ovarian Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2237
91. Gastrointestinal Infections and Judith A. Smith and Judith K. Wolf
Enterotoxigenic Poisonings . . . . . . . . . . . . . . . . . . . . . . 1807
Steven Martin and Rose Jung 111. Acute Leukemias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2255
Betsy Bickert Poon and Amy Hateld Seung
92. Intraabdominal Infections . . . . . . . . . . . . . . . . . . . . . . . 1821
Keith M. Olsen, Alan E. Gross, and Joseph T. DiPiro 112. Chronic Leukemias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2277
Christopher A. Fausel and Patrick J. Kiel
93. Parasitic Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1835
JV Anandan 113. Multiple Myeloma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2295
Casey B. Williams and Timothy R. McGuire
94. Urinary Tract Infections and Prostatitis . . . . . . . . . . . 1849
Elizabeth A. Coyle and Randall A. Prince 114. Myelodysplastic Syndromes . . . . . . . . . . . . . . . . . . . . . 2313
Julianna A. Merten, Kristen B. McCullough,
95. Sexually Transmitted Diseases . . . . . . . . . . . . . . . . . . . 1867 and Mrinal M. Patnaik
Leroy C. Knodel
115. Renal Cell Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2331
96. Bone and Joint Infections . . . . . . . . . . . . . . . . . . . . . . . . 1885 Christine M. Walko and Ashley E. Simmons
Edward P. Armstrong and Ziad Shehab
116. Melanoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2347
97. Severe Sepsis and Septic Shock . . . . . . . . . . . . . . . . . . 1897 Cindy L. OBryant and Jamie C. Poust
S. Lena Kang-Birken
117. Hematopoietic Stem Cell Transplantation . . . . . . . . 2367
98. Supercial Fungal Infections . . . . . . . . . . . . . . . . . . . . . 1911 Susanne Liewer and Janelle Perkins
Thomas E. R. Brown and Linda D. Dresser
xv
CONTRIBUTORS
Department of Pharmacy
Lucinda M. Buys, PharmD, BCPS National Cancer Centre Singapore
Associate Professor Singapore, Singapore
Department of Pharmacy Practice and Science Chapter 109
University of Iowa
College of Pharmacy and The Siouxland Medical C. Y. Jennifer Chan, PharmD
Education Foundation Clinical Assistant Professor of Pharmacy
Sioux City, Iowa Pharmacotherapy Education and Research Center
Chapter 71 University of Texas at Austin College of Pharmacy
Adjunct Associate Professor of Pediatrics
Karim Anton Calis, PharmD, MPH, FASHP, FCCP Department of Pediatrics
Clinical Investigator University of Texas Health Science Center
Office of the Clinical Director San Antonio, Texas
Eunice Kennedy Shriver National Institute of Child Health Chapter 82
and Human Development
National Institutes of Health Jack J. Chen, PharmD, BCPS
Bethesda, Maryland Associate Professor
Clinical Professor Department of Neurology
Department of Pharmacy Practice and Science Movement Disorders Clinic
School of Pharmacy, University of Maryland Schools of Medicine and Pharmacy
Baltimore, Maryland Loma Linda University
Clinical Professor Loma Linda, California
Department of Pharmacotherapy and Outcomes Science Chapter 43
School of Pharmacy
Virginia Commonwealth University Judy T. Chen, PharmD, BCPS
Richmond, Virginia Clinical Associate Professor
Chapters 60, 65, and 121 Department of Pharmacy Practice
Purdue University College of Pharmacy
Peggy L. Carver, PharmD, FCCP Clinical Pharmacy Specialist
Associate Professor of Pharmacy The Jane Pauley Community Health Center, Inc.
Clinical Pharmacist, Infectious Diseases Indianapolis, Indiana
Department of Clinical, Social, and Administrative Sciences Chapter 121
University of Michigan College of Pharmacy and University
of Michigan Health System Katherine Hammond Chessman, BSPharm, PharmD
Ann Arbor, Michigan Professor
Chapter 99 Clinical Pharmacy and Outcomes Sciences
South Carolina College of Pharmacy, MUSC Campus
Larisa H. Cavallari, PharmD Clinical Pharmacy Specialist, Pediatrics/Pediatric Surgery
Associate Professor Department of Pharmacy Services
Department of Pharmacy Practice The Childrens Hospital of South Carolina
University of Illinois at Chicago Charleston, South Carolina
Chicago, Illinois Chapters 34, 118, and 120
eChapter 6
Chapter 4 Elaine Chiquette
San Antonio, Texas
Jose E. Cavazos, MD, PhD eChapter 4
Professor
Departments of Neurology, Pharmacology and Physiology Mariann D. Churchwell, PharmD, BCPS
Assistant Dean for MD/PhD Program Associate Professor
The University of Texas Health Science Center at San Antonio University of Toledo College of Pharmacy
San Antonio, Texas Toledo, Ohio
Chapter 40 Chapter 30
Chapter 89
Nathan P. Clark, PharmD, BCPS
Clinical Pharmacy Supervisor William Dager, PharmD, BCPS (AQ Cardiology)
Clinical Pharmacy Pharmacist Specialist
Anticoagulation and Anemia Service UC Davis Medical Center
Kaiser Permanente Clinical Professor of Pharmacy
Aurora, Colorado UC San Francisco School of Pharmacy
Chapter 9 Clinical Professor of Medicine
UC Davis School of Medicine
Kristen Cook, PharmD, BCPS Clinical Professor of Pharmacy
Assistant Professor Touro School of Pharmacy
Department of Pharmacy Practice Sacramento, California
College of Pharmacy Chapter 28
University of Nebraska Medical Center
Omaha, Nebraska Devra K. Dang, PharmD, BCPS, CDE
Chapter 80 Associate Clinical Professor
University of Connecticut
John R. Corboy, MD School of Pharmacy
Professor Storrs, Connecticut
Department of Neurology Chapter 65
University of Colorado School of Medicine
Co-Director Joseph F. Dasta, MSc, FCCM, FCCP
Rocky Mountain MS Center Adjunct Professor
University of Colorado The University of Texas
Anschutz Medical Campus Professor Emeritus
Aurora, Colorado The Ohio State University
Chapter 39 Austin, Texas
Chapter 13
Lisa T. Costanigro, PharmD, BCPS
Staff Pharmacist Dewayne A. Davidson, PharmD
Poudre Valley Health System Assistant Professor
Fort Collins, Colorado Department of Family and Community Medicine
eChapter 11 The University of Texas Health Science Center at San Antonio
San Antonio, Texas
Elizabeth A. Coyle, PharmD, FCCM, BCPS eChapter 1
Assistant Dean of Assessment
Clinical Professor Lisa E. Davis, BS, PharmD
University of Houston Professor of Clinical Pharmacy
College of Pharmacy Philadelphia College of Pharmacy
Houston, Texas University of the Sciences in Philadelphia
Chapter 94 Philadelphia, Pennsylvania
Chapter 107
Catherine M. Crill, PharmD, BCPS, BCNSP, FCCP
Associate Professor Brian S. Decker, MD, PharmD, MS
Departments of Clinical Pharmacy and Pediatrics Assistant Professor of Clinical Medicine
The University of Tennessee Health Science Center Department of Medicine, Division of Nephrology
Memphis, Tennessee Indiana University School of Medicine
Chapter 119 Indianapolis, Indiana
Chapter 30
M. Lynn Crismon, PharmD
Dean Timothy Dellenbaugh, MD
James T. Doluisio Regents Chair and Behrens Centennial Professor Associate Professor
College of Pharmacy Department of Psychiatry
The University of Texas at Austin University of Missouri-Kansas City
Austin, Texas Center for Behavioral Medicine
Chapter 50 Kansas City, Missouri
eChapter 20
CONTRIBUTORS
Chapter 26
Shannon J. Drayton, PharmD, BCPP
Simon de Denus, B.Pharm, MSc, PhD Associate Professor
Research Pharmacist Clinical Pharmacy and Outcomes Sciences
Montreal Heart Institute South Carolina College of Pharmacy
Associate Professor Medical University of South Carolina
Faculty of Pharmacy Universit de Montral Charleston, South Carolina
Universit de Montral Beaulieu-Saucier Chapter 52
Chair in Pharmacogenomics
Montreal, Quebec Linda D. Dresser, PharmD, FCSHP
Chapter 7 Assistant Professor
Leslie Dan Faculty of Pharmacy
John W. Devlin, PharmD, FCCP, FCCM University of Toronto
Associate Professor University Health Network, Toronto
Department of Pharmacy Practice Ontario, Canada
Bouve College of Health Professions Chapter 98
Northeastern University
Boston, Massachusetts Deepak P. Edward, MD
Chapter 37 Jonas S Friedenwald Professor of Ophthalmology and Pathology
Department of Ophthalmology
Eric Dietrich, PharmD Wilmer Eye Institute
Post Doctoral Fellow Johns Hopkins University
Family Medicine College of Pharmacy and Medicine Baltimore, Maryland
University of Florida Chapter 75
Gainesville, Florida
Chapter 59 Mary Elizabeth Elliott, PharmD, PhD
Associate Professor
Cecily V. DiPiro, PharmD Pharmacy Practice Division
Consultant Pharmacist School of Pharmacy
Mount Pleasant, South Carolina University of Wisconsin
Chapter 22 Madison, Wisconsin
Chapter 71
Joseph T. DiPiro, PharmD, FCCP
Executive Dean and Professor Ramy H. Elshaboury, PharmD
South Carolina College of Pharmacy Pharmacy Resident in Infectious Diseases
University of South Carolina and Medical University Department of Pharmacy
of South Carolina Abbott Northwestern Hospital, Part of Allina Health
Charleston and Columbia, South Carolina Minneapolis, Minnesota
Chapter 92 Chapter 84
CONTRIBUTORS
Chapter 59
Lauren R. Hersh, MD
Emily R. Hajjar, PharmD, BCPS, BCAP, CGP Instructor
Associate Professor Department of Family and Community Medicine
Department of Pharmacy Practice Thomas Jefferson University
Jefferson School of Pharmacy Philadelphia, Pennsylvania
Thomas Jefferson University eChapter 8
Philadelphia, Pennsylvania
eChapter 8 David C. Hess, MD
Professor and Chairman
Jenana Halilovic, PharmD, BCPS, AAHIVP Department of Neurology
Assistant Professor Medical College of Georgia
Department of Pharmacy Practice Augusta, Georgia
Thomas J Long School of Pharmacy and Health Sciences Chapter 10
Stockton, California
Chapter 28 Angela Massey Hill, PharmD, BCPP, CPH
Professor and Chair
Philip D. Hall, PharmD, FCCP, BCPS, BCOP Department of Pharmacotherapeutics
Campus Dean and Professor University of South Florida College of Pharmacy
South Carolina College of Pharmacy Tampa, Florida
Medical University of South Carolina Chapter 38
Charleston, South Carolina
eChapter 21 L. David Hillis, MD
Professor and Chair
Joseph T. Hanlon, PharmD, MS Department of Medicine
Professor University of Texas Health Science Center
Department of Medicine, Pharmacy and Therapeutics, and San Antonio, Texas
Epidemiology eChapter 13
University of Pittsburgh Chapter 1
Pittsburgh, Pennsylvania
eChapter 8 Barbara J. Hoeben, PharmD, MSPharm, BCPS
Pharmacy Flight Commander
Michelle Harkins, MD Davis-Monthan Air Force Base
Associate Professor of Medicine Tucson, Arizona
Department of Internal Medicine Chapter 12
University of New Mexico Health Sciences Center
Albuquerque, New Mexico Jessica S. Holt, PharmD, BCPS, AQ-ID
eChapter 15 Infectious Diseases Pharmacy Coordinator
Department of Pharmacy
Mary S. Hayney, PharmD, MPH, FCCP, BCPS Abbott Northwestern Hospital, Part of Allina Health
Professor of Pharmacy Minneapolis, Minnesota
University of Wisconsin School of Pharmacy Chapter 84
Madison, Wisconsin
Chapter 102 Joanna Q. Hudson, PharmD, BCPS, FASN, FCCP
Associate Professor
Brian A. Hemstreet, PharmD, FCCP, BCPS Departments of Clinical Pharmacy and Medicine (Nephrology)
Associate Professor The University of Tennessee Health Science Center
Department of Clinical Pharmacy Memphis, Tennessee
University of Colorado Skaggs School of Pharmacy Chapter 29
and Pharmaceutical Sciences
Aurora, Colorado Grant F. Hutchins, MD
Chapter 21 Assistant Professor, Internal Medicine
Division of Gastroenterology-Hepatology
Elizabeth D. Hermsen, PharmD, MBA, BCPS-ID University of Nebraska Medical Center
Clinical Scientific Director Omaha, Nebraska
Cubist Pharmaceuticals, Inc. eChapter 16
Lexington, Massachusetts
Adjunct Associate Professor
Department of Pharmacy Practice
College of Pharmacy, University of Nebraska Medical Center
Omaha, Nebraska
Chapters 84 and 87
Chapter 22
Associate Professor
Arthur A. Islas, MD, MPH Department of Pharmacy Practice
Associate Professor and Director of Sports Medicine School of Pharmacy and Health Sciences
Department of Family and Community Medicine University of the Pacific
Paul L. Foster School of Medicine Stockton, California
Texas Tech University Health Sciences Center-El Paso Chapter 97
El Paso, Texas
eChapter 2 Salmaan Kanji, PharmD, BSc, Pharm, ACPR
Clinical Pharmacy Specialist
Heather J. Johnson, PharmD, BCPS The Ottawa Hospital
Assistant Professor Associate Scientist
Department of Pharmacy and Therapeutics Ottawa Hospital Research Institute
University of Pittsburgh School of Pharmacy Adjunct Professor of Pharmacy
Pittsburgh, Pennsylvania University of Montreal
Chapter 70 Assistant Professor of Medicine
University of Ottawa
Shawn E. Johnson, PharmD, MPH Pharmacy, Clinical Epidemiology
Clinical Generalist Pharmacist Ottawa, Ontario, Canada
Department of Pharmacy Chapter 101
The Ohio State University Wexner Medical Center
Columbus, Ohio H. William Kelly, PharmD
eChapter 3 Professor Emeritus Pediatrics
Department of Pediatrics
Jacqueline Jonklaas, MD, PhD University of New Mexico Health Sciences Center
Associate Professor Albuquerque, New Mexico
Division of Endocrinology Chapter 15
Department of Medicine
Georgetown University Patrick J. Kiel, PharmD, BCPS, BCOP
Washington, District of Columbia Clinical Pharmacy Specialist, Hematology/Stem Cell Transplant
Chapter 58 Department of Pharmacy
Indiana University Simon Cancer Center
Joseph K. Jordan, PharmD Indianapolis, Indiana
Associate Professor Chapter 112
Drug Information Specialist
Department of Pharmacy Practice William R. Kirchain, PharmD, CDE
Butler University College of Pharmacy and Health Sciences Wilbur and Mildred Robichaux Endowed Professorship
Indiana University Health Division of Clinical and Administrative Sciences
Indianapolis, Indiana Xavier University of Louisiana
Chapter 60 College of Pharmacy
New Orleans, Louisiana
Rose Jung, PharmD, MPH, BCPS eChapter 17
Clinical Associate Professor
Department of Pharmacy Practice Cynthia K. Kirkwood, PharmD, BCPP
College of Pharmacy and Pharmaceutical Sciences Professor
University of Toledo Vice Chair for Education
Toledo, Ohio Department of Pharmacotherapy and Outcomes Science
Chapter 91 School of Pharmacy
Virginia Commonwealth University
Thomas N. Kakuda, PharmD Richmond, Virginia
Scientific Director Chapters 53 and 54
Department of Clinical Pharmacology
Janssen Research & Development, LLC Jacqueline Klootwyk, PharmD, BCPS
Titusville, New Jersey Assistant Professor of Pharmacy Practice
Chapter 103 Jefferson School of Pharmacy
Thomas Jefferson University
Sophia N. Kalantaridou, MD, PhD Philadelphia, Pennsylvania
Professor of Obstetrics and Gynecology Chapter 63
Department of Obstetrics and Gynecology
University of Ioannina Medical School
Ioannina, Greece
Chapter 65
CONTRIBUTORS
College of Pharmacy Providence Veterans Affairs Medical Center
The University of Texas at Austin Adjunct Associate Professor of Medicine
Austin, Texas Division of Infectious Diseases
Chapter 95 Warren Alpert School of Medicine
Brown University
Jill M. Kolesar, PharmD, BCPS, FCCP Kingston, Rhode Island
Professor eChapter 25
School of Pharmacy
University of Wisconsin Alan H. Lau, PharmD, FCCP
Madison, Wisconsin Professor
Chapter 108 Department of Pharmacy Practice
Director, International Clinical Pharmacy Education
Sunil Kripalani, MD, MSc University of Illinois at Chicago, College of Pharmacy
Associate Professor Chicago, Illinois
Section of Hospital Medicine Chapter 32
Division of General Internal Medicine and Public Health
Department of Medicine Michael Lauzardo, MD, MSc
Vanderbilt University Chief
Nashville, Tennessee Division of Infectious Diseases and Global Medicine
eChapter 1 Director
Southeastern National Tuberculosis Center
Vanessa J. Kumpf, PharmD, BCNSP College of Medicine
Clinical Specialist, Nutrition Support University of Florida
Center for Human Nutrition Gainesville, Florida
Vanderbilt Medical Center Chapter 90
Nashville, Tennessee
Chapters 118 and 120 David T.S. Law, BSc, MD, PhD, CCFP
Assistant Professor
Po Gin Kwa, MD, FRCPC Department of Family and Community Medicine
Clinical Assistant, Professor of Pediatrics Faculty of Medicine
Faculty of Medicine University of Toronto
Memorial University of Newfoundland and Pediatrician Staff, Department of Family Practice
Eastern Health The Scarborough Hospital and Rouge Valley Health System
St. Johns, Newfoundland, Canada Scarborough, Ontario, Canada
Chapter 79 eChapter 23
Sum Lam, PharmD, CGP, BCPS, FASCP Rebecca M. Law, PharmD
Associate Clinical Professor School of Pharmacy and Discipline of Family Medicine
Department of Clinical Pharmacy Practice Faculty of Medicine
St. Johns University Memorial University of Newfoundland
Queens, New York St. Johns Newfoundland, Canada
Chapter 68 eChapter 23
Y. W. Francis Lam, PharmD, FCCP Chapters 78 and 79
Professor of Pharmacology and Medicine Grace C. Lee, PharmD, BCPS
Department of Pharmacology Clinical Instructor
The University of Texas Health Science Center at San Antonio Division of Pharmacotherapy
San Antonio, Texas College of Pharmacy
Clinical Associate Professor of Pharmacy University of Texas at Austin
University of Texas at Austin Austin, Texas
Austin, Texas Chapter 83
eChapter 6
Mary Lee, PharmD, BCPS, FCCP
Richard A. Lange, MD, MBA Professor of Pharmacy Practice
Professor and Executive Vice Chairman Chicago College of Pharmacy
Department of Medicine Midwestern University
The University of Texas Health Science Center Downers Grove, Illinois
San Antonio, Texas Chapters 66 and 67
eChapter 13
Chapter 1
Chapter 75 Chapter 80
Deborah J. Levine, MD, FCCP Robert MacLaren, BBSc, PharmD, MPH, FCCM, FCCP
Associate Professor of Medicine Professor
Division of Pulmonary and Critical Care Department of Clinical Pharmacy
University of Texas Skaggs School of Pharmacy and Pharmaceutical Sciences
San Antonio, Texas University of Colorado Denver
Chapter 17 Aurora, Colorado
Chapter 13
Stephanie M. Levine, MD
Professor of Medicine Eric J. MacLaughlin, PharmD, FASHP, FCCP, BCPS
Division of Pulmonary Diseases and Critical Care Medicine Professor and Interim Chair
The University of Texas Health Science Center Department of Pharmacy Practice
San Antonio, Texas Professor
eChapter 14 Departments of Family Medicine and Internal Medicine
Texas Tech University Health Sciences Center School of Pharmacy
Robin Moorman Li, PharmD, BCACP Amarillo, Texas
Assistant Director Chapter 3
Jacksonville Campus
Clinical Assistant Professor Robert L. Maher Jr, PharmD, CGP
Department of Pharmacotherapy and Translational Research Assistant Professor of Pharmacy Practice
University of Florida, College of Pharmacy Clinical, Social, and Administrative Sciences Division
Gainesville, Florida Duquesne University Mylan School of Pharmacy
Chapters 48 and 49 Pittsburgh, Pennsylvania
eChapter 8
Susanne Liewer, PharmD, BCOP
Clinical Pharmacy Coordinator, Stem Cell Transplant Robert A. Mangione, EdD, RPh
Department of Pharmaceutical and Nutrition Care Provost and Professor of Pharmacy
The Nebraska Medical Center Office of the Provost
Clinical Assistant Professor St. Johns University
Department of Pharmacy Practice Queens, New York
College of Pharmacy Chapter 27
University of Nebraska Medical Center
Omaha, Nebraska Steven Martin, PharmD
Chapter 117 Professor and Chairman
Department of Pharmacy Practice
Bryan L. Love, PharmD College of Pharmacy and Pharmaceutical Sciences
Associate Professor The University of Toledo
Department of Clinical Pharmacy and Outcomes Science Toledo, Ohio
South Carolina College of Pharmacy Chapter 91
Clinical Pharmacy Specialist
Departments of Pharmacy and Gastroenterology/Hepatology Todd W. Mattox, PharmD, BCNSP
William Jennings Bryan Dorn Veterans Affairs Medical Center Critical Care
Columbia, South Carolina Nutrition Support Pharmacy Specialist
Chapter 20 Department of Pharmacy
Moffitt Cancer Center
Amanda M. Loya, PharmD Tampa, Florida
Clinical Associate Professor Chapter 119
University of Texas at El Paso
UT Austin Cooperative Pharmacy Program Gary R. Matzke, PharmD, FCP, FCCP, FASN, FNAP
University of Texas at El Paso College of Health Sciences Professor and Director
University of Texas at Austin College of Pharmacy Pharmacy Practice Transformation Initiatives
Adjunct Clinical Assistant Professor and Founding Director
Department of Family and Community Medicine ACCP/ASHP/VCU Congressional Health Care Policy
Texas Tech University Health Sciences CenterEl Paso Fellow Program
El Paso, Texas Department of Pharmacotherapy and Outcome Sciences
eChapter 2 School of Pharmacy, Virginia Commonwealth University
Richmond, Virginia
Chapters 33, 34, and 37
CONTRIBUTORS
Augusta, Georgia Chapter 45
Chapter 19
Augusto Miravalle, MD
J. Russell May, PharmD Assistant Professor
Clinical Professor Department of Neurology
Department of Clinical and Administrative Pharmacy University of Colorado School of Medicine
University of Georgia College of Pharmacy Associate Director
Augusta, Georgia Neurology Residency Program
Chapter 76 University of Colorado
Anschutz Medical Campus
Kristen B. McCullough, PharmD, BCPS, BCOP Aurora, Colorado
Clinical Pharmacist Chapter 39
Department of Pharmacy Services
Mayo Clinic Isaac F. Mitropoulos, BS, PharmD
Rochester, Minnesota Senior Medical Education and Research Liaison
Chapter 114 Department of Medical Affairs
Optimer Pharmaceuticals, Inc.
Timothy R. McGuire, PharmD, FCCP, BCOP Chapel Hill, North Carolina
Associate Professor Chapter 84
Department of Pharmacy Practice
College of Pharmacy Rima A. Mohammad, PharmD, BCPS
University of Nebraska Medical Center Assistant Professor
Omaha, Nebraska Department of Pharmacy and Therapeutics
Chapter 113 School of Pharmacy
University of Pittsburgh
Jerry R. McKee, PharmD, MS, BCPP Pittsburgh, Pennsylvania
Regional Dean Chapter 33
Associate Professor of Pharmacy
Wingate University Hendersonville Campus Patricia A. Montgomery, PharmD
Hendersonville, North Carolina Adjunct Professor
Chapter 56 Thomas J. Long School of Pharmacy and Health Sciences
University of the Pacific
Patrick J. Medina, PharmD, BCOP Sacramento, California
Associate Professor Chapter 25
The University of Oklahoma
College of Pharmacy Rebecca Moote, PharmD, MSc, BCPS
Oklahoma City, Oklahoma Assistant Professor
Chapters 104 and 107 Department of Pharmacy Practice
Regis University School of Pharmacy
Sarah T. Melton, PharmD, BCPP, BCACP, CGP, FASCP Denver, Colorado
Associate Professor of Pharmacy Practice Chapter 17
Department of Pharmacy Practice
Gatton College of Pharmacy at East Tennessee State University Scott W. Mueller, PharmD
Johnson City, Tennessee Assistant Professor
Chapters 53 and 54 Department of Clinical Pharmacy
Skaggs School of Pharmacy and Pharmaceutical Sciences
Julianna A. Merten, PharmD, BCPS, BCOP University of Colorado Anschutz Medical Campus
Clinical Pharmacy Specialist Clinical Specialist in Critical Care
Department of Pharmacy Services University of Colorado Hospital
Mayo Clinic Aurora, Colorado
Rochester, Minnesota Chapter 100
Chapter 114
Milap C. Nahata, PharmD, MS, FCCP
Laura Boehnke Michaud, PharmD, BCOP, FASHP Professor of Pharmacy
Manager, Clinical Pharmacy Services Pediatrics and Internal Medicine
Division of Pharmacy Division Chair
Clinical Pharmacy Services Pharmacy Practice and Administration College of Pharmacy
The University of Texas M. D. Anderson Cancer Center Ohio State University
Houston, Texas Associate Director of Pharmacy
Chapter 105 The Ohio State University Medical Center
Columbus, Ohio
eChapter 7
CONTRIBUTORS
MUSC Campus
Charles A. Peloquin, PharmD Medical University of South Carolina
Professor Department of Pharmacy Services
College of Pharmacy and Emerging Pathogens Institute Charleston, South Carolina
University of Florida eChapter 21
Gainesville, Florida
Chapter 90 Kathleen J. Pincus, PharmD, BCPS
Assistant Professor
Susan L. Pendland, MS, PharmD Department of Pharmacy Practice and Sciences
Adjunct Associate Professor of Pharmacy Practice University of Maryland
University of Illinois at Chicago School of Pharmacy
Chicago, Illinois Baltimore, Maryland
Clinical Staff Pharmacist, St. Joseph Berea Hospital Chapter 64
Berea, Kentucky
Chapter 88 Stephen R. Pliszka, MD
Professor and Chief
Janelle Perkins, PharmD, BCOP Division of Child and Adolescent Psychiatry
Associate Professor Department of Psychiatry
Departments of Pharmacotherapeutics, The University of Texas Health Science Center at San Antonio
Clinical Research and Oncologic Sciences San Antonio, Texas
Colleges of Pharmacy and Medicine Chapter 46
University of South Florida
Tampa, Florida Betsy Bickert Poon, PharmD
Chapter 117 Assistant Director of Pharmacy
Pediatric Hematology/Oncology/Stem Cell Transplant Specialist
Emily P. Peron, PharmD, MS, BCPS, FASCP Walt Disney Pavilion at Florida Hospital for Children
Assistant Professor Orlando, Florida
Geriatric Pharmacotherapy Program Chapters 81 and 111
Department of Pharmacotherapy and Outcomes Science
Virginia Commonwealth University L. Michael Posey, BSPharm, MA
School of Pharmacy Associate Vice President
Richmond, Virginia Periodicals Department
Chapter 38 American Pharmacists Association
Washington, District of Columbia
Jay I. Peters, MD eChapter 4
Professor and Chief
Division of Pulmonary Critical Care Jamie C. Poust, PharmD, BCOP
University of Texas Health Science Center Oncology Pharmacy Specialist
San Antonio, Texas Department of Pharmacy
eChapter 14 University of Colorado Hospital
Anschutz Inpatient Pavilion
Stephanie J. Phelps, PharmD, BSPharm Aurora, Colorado
Professor Chapter 116
Clinical Pharmacy and Pediatrics
College of Pharmacy and Pediatrics Randall A. Prince, PharmD, PhD
The University of Tennessee Health Science Center Professor
Memphis, Tennessee University of Houston College of Pharmacy
Chapter 41 Houston, Texas
Chapter 94
Bradley G. Phillips, PharmD, BCPS, FCCP
Milliken-Reeve Professor and Head Jane Pruemer, PharmD, BCOP
Department of Clinical and Administrative Pharmacy Professor of Clinical Pharmacy Practice
University of Georgia College of Pharmacy Department of Pharmacy Practice and Administrative Sciences
Athens, Georgia James L. Winkle College of Pharmacy
Chapter 55 University of Cincinnati
Cincinnati, Ohio
Chapter 81
Chapter 62 Chapter 69
Thomas Repas, DO, FACP, FACOI, FNLA, FACE, CDE Michael J. Rybak, PharmD, MPH
Clinical Assistant Professor Professor of Pharmacy and Medicine
Department of Internal Medicine Director
Sanford School of Medicine Anti Infective Research Laboratory
University of South Dakota Department of Pharmacy Practice
Sioux Falls, South Dakota Eugene Applebaum College of Pharmacy
Chapter 57 Wayne State University
Detroit, Michigan
eChapter 25
CONTRIBUTORS
Chapter 8
Amy Heck Sheehan, PharmD
Joseph J. Saseen, PharmD, FASHP, FCCP, BCPS Associate Professor
Professor and Vice Chair Department of Pharmacy Practice
Department of Clinical Pharmacy Purdue University College of Pharmacy
Professor Drug Information Specialist
Department of Family Medicine Indiana University Health System
University of Colorado Anschutz Medical Campus Indianapolis, Indiana
Skaggs School of Pharmacy and Pharmaceutical Sciences Chapters 60 and 121
Aurora, Colorado
Chapter 3 Ziad Shehab, MD
Professor
Mark E. Schneiderhan, PharmD, BCPP Departments of Pediatrics and Pathology
Associate Professor University of Arizona College of Medicine
Department of Pharmacy Practice and Pharmaceutical Sciences Tucson, Arizona
Department of Psychiatry Chapter 96
University of Minnesota, College of Pharmacy
Duluth/Human Development Center Greene Shepherd, PharmD
Duluth, Minnesota Clinical Professor
eChapter 20 Department of Practice Advancement and Clinical Education
UNC Eshelman School of Pharmacy
Kristine S. Schonder, PharmD Asheville, North Carolina
Assistant Professor eChapter 12
Department of Pharmacy and Therapeutics
University of Pittsburgh School of Pharmacy Stacy S. Shord, PharmD, BCOP, FCCP
Pittsburgh, Pennsylvania Reviewer
Chapter 70 Office of Clinical Pharmacology
Office of Translational Science
Arthur A. Schuna, MS, BCACP Center for Drug Evaluation and Research
Clinical Coordinator U.S. Food and Drug Administration
Department of Pharmacy Service Silver Spring, Maryland
William S. Middleton VA Hospital Chapter 104
Clinical Professor
Department of Pharmacy Practice Sarah P. Shrader, PharmD, BCPS, CDE
University of Wisconsin School of Pharmacy Clinical Associate Professor
Madison, Wisconsin Department of Pharmacy Practice
Chapter 72 University of Kansas
School of Pharmacy
Richard B. Schwartz, MD Lawrence, Kansas
Professor and Chair Chapter 62
Department of Emergency Medicine
Medical College of Georgia Jeri J. Sias, PharmD, MPH
Augusta, Georgia Clinical Associate Professor
eChapter 12 University of Texas at El Paso
UT Austin Cooperative Pharmacy Program
Julie M. Sease, PharmD, BCPS, BCACP University of Texas at El Paso College of Health Sciences
Associate Professor University of Texas at Austin College of Pharmacy
Department of Pharmacy Practice Adjunct Clinical Assistant Professor
Presbyterian College School of Pharmacy Department of Family and Community Medicine
Clinton, South Carolina Texas Tech University Health Sciences CenterEl Paso
Chapter 24 El Paso, Texas
eChapter 2
Amy Hateld Seung, PharmD, BCOP
Oncology Pharmacy Clinical Specialist Debra Sibbald, BScPhm, RPh, ACPR, MA, PhD
PGY2 Oncology Residency Director Senior Lecturer
Department of Pharmacy Division of Pharmacy Practice
Sidney Kimmel Comprehensive Cancer Center Leslie Dan Faculty of Pharmacy
Johns Hopkins Hospital University of Toronto
Baltimore, Maryland Director
Chapter 111 Department of Assessment Services
Centre for the Evaluation of Health Professionals Educated Abroad
Toronto, Ontario
Chapter 77
Chapter 115
Catherine I. Starner, PharmD, BCPS
Tamara D. Simpson, MD Senior Health Outcomes Researcher
Associate Professor of Medicine Medication Therapy Management
Division of Pulmonary and Critical Care Prime Therapeutics, LLC
University of Texas Health Science Center at San Antonio Adjunct Assistant Professor
San Antonio, Texas Experimental and Clinical Pharmacology
eChapter 14 College of Pharmacy
University of Minnesota
Patricia W. Slattum, PharmD, PhD Minneapolis, Minnesota
Director, Geriatric Pharmacotherapy Program eChapter 8
Department of Pharmacotherapy and Outcomes Science
Virginia Commonwealth University, School of Pharmacy Douglas W. Stewart, DO, MPH
Richmond, Virginia Associate Professor
eChapter 8 Department of Pediatrics
Chapter 38 School of Community Medicine
The University of Oklahoma
Judith A. Smith, PharmD, BCOP, CPHQ, FCCP, FISOPP Tulsa, Oklahoma
Associate Professor and Director, Pharmacology Research Chapter 56
Department of Gynecologic Oncology and Reproductive Medicine
Division of Surgery Steven C. Stoner, PharmD, BCPP
Program Director, Oncology Translational Research Fellowship Clinical Professor and Chair
Division of Pharmacy UMKC School of Pharmacy
University of Texas M.D. Anderson Cancer Center Division of Pharmacy Practice and Administration
Houston, Texas Kansas City, Missouri
Chapter 110 Chapter 47
CONTRIBUTORS
School of Pharmacy Chapter 63
Boston, Massachusetts
eChapter 22 Yolanda Y. Vera, PharmD
Pediatric Patient Care Pharmacist
Carol Taketomo, PharmD Department of Pharmacy
Director of Pharmacy and Clinical Nutrition McLane Childrens Hospital
Childrens Hospital of Los Angeles Temple, Texas
Adjunct Assistant Professor of Pharmacy Practice Chapter 18
University of Southern California
School of Pharmacy Angie Veverka, PharmD, BCPS
Los Angeles, California PGY1 Pharmacy Residency Director, Clinical Specialist,
eChapter 7 Internal Medicine
Department of Pharmacy
Robert L. Talbert, PharmD, FCCP, BCPS, FAHA Carolinas Medical Center
Professor Charlotte, North Carolina
Pharmacotherapy Division Chapter 89
College of Pharmacy
University of Texas at Austin Kimberly Wahl, PharmD
Professor Ambulatory Care Clinical Pharmacist
Department of Medicine Department of Pharmacy
School of Medicine Ralph H. Johnson VA Medical Center, Myrtle Beach CBOC
University of Texas Health Science Center at San Antonio Myrtle Beach, South Carolina
San Antonio, Texas Chapter 72
Chapters 6, 11, 12, and 58 Christine M. Walko, PharmD, BCOP
Colleen M. Terri, PharmD, BCPS (AQ-ID), Assistant Professor
Division of Pharmacotherapy and Experimental Therapeutics
AAHIVP, MPH International Medicine
Institute of Pharmacogenomics and Individualized Therapy
Clinical Associate Professor
University of North Carolina Eshelman School of Pharmacy
Department of Pharmacotherapy
Lineberger Comprehensive Cancer Center
Washington State University, College of Pharmacy
University of North Carolina
Deaconess Hospital
Chapel Hill, North Carolina
Spokane, Washington
Chapter 115
eChapter 11
Kristina E. Ward, BS, PharmD, BCPS
Christian J. Teter, PharmD, BCPP
Clinical Associate Professor of Pharmacy Practice
Assistant Professor, Psychopharmacology
Director, Drug Information Services
College of Pharmacy
Department of Pharmacy Practice
University of New England
University of Rhode Island
Portland, Maine
College of Pharmacy
Chapter 51
Kingston, Rhode Island
Matthew N. Thoma, MD Chapter 61
Assistant Professor of Clinical Medicine
Department of Internal Medicine
Lori D. Wazny, PharmD
Clinical Pharmacist
University of South Carolina School of Medicine
Manitoba Renal Program
Staff Gastroenterologist
Winnipeg, Manitoba, Canada
Department of Gastroenterology/Hepatology
Chapter 29
WJB Dorn VA Medical Center
Columbia, South Carolina Robert J. Weber, PharmD, MS
Chapter 20 Senior Director, Pharmaceutical Services
Department of Pharmacy
Curtis L. Triplitt, PharmD, CDE
The Ohio State University Wexner Medical Center
Clinical Assistant Professor
Columbus, Ohio
Department of Medicine
eChapter 3
Division of Diabetes
University of Texas Health Science Center at San Antonio Barbara G. Wells, PharmD, FCCP, FASHP
Texas Diabetes Institute Dean Emeritus and Professor Emeritus
University Health System Department of Pharmacy Practice
San Antonio, Texas University of Mississippi, School of Pharmacy
Chapter 57 Oxford, Mississippi
Chapters 51 and 54
Neuroscience Institute
LeBonheur Childrens Hospital Judith K. Wolf, MD
Memphis, Tennessee Adjunct Professor of Gynecologic Oncology
Chapter 41 Division Chief of Surgery
Banner MD Anderson Cancer Center
Casey B. Williams, PharmD, BCOP Clinical Professor
Director of Clinical Research University of Texas MD Anderson Cancer Center
Sanford Research/University of South Dakota Gilbert, Arizona
Assistant Clinical Professor Chapter 110
Department of Internal Medicine
University of South Dakota Sanford School of Medicine G. Christopher Wood, PharmD, FCCP, FCCM, BCPS
Adjunct Assistant Clinical Professor Associate Professor of Clinical Pharmacy
Department of Pharmacy Practice Department of Clinical Pharmacy
University of Kansas School of Pharmacy University of Tennessee Health Science Center
Sioux Falls, South Dakota Memphis, Tennessee
Chapter 113 Chapter 42
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