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Incidence and Clinical profile of Ischemic Stroke in Neurology Division,

Department of Child Health, Cipto Mangunkusumo Hospital


Reni Fahriani, RA Setyo Handryastuti
Department of Child Health, Cipto Mangunkusumo Hospital
Medical School University of Indonesia, Jakarta, Indonesia

Background : Stroke is defined as rapidly developing clinical signs of focal disturbance of cerebral
function. Stroke in childhood is a rare occurrence, and its clinical presentation is often subtle
therefore general pediatricians should know the early clinical manifestatioan to detect
ischemic stroke in children.

Objective: : To find out the clinical profile of ischemic stroke in children.

Method: Retrospective study of medical record was conducted of children who carried a diagnosis of
ischemic stroke from 2005-2010. Variables studied were sex, age at the time of episode, motor
deficits, presence of seizure, imaging findings, etiology, treatment and outcome.

Results: During 5 years periode, thirteen patients were diagnosed. Average age at presentation was
5.5 years. Six patients (46.2%) were female, and 7 patients (53.8%) were male. The most frequent
neurological deficit was left hemiparesis (38.5%). One patient had deafness as first manifestation.
Only 4 patients (30.8%) experienced seizures. Coagulation disorder (69%) was the most frequent
etiologies of ischemic stroke in our patients, although there were 3 patients had unknown etiology
due to incomplete examinations. None of the patients had underlying disease like sickle cella
anemia, moya-moya, heart disease, and CNS infection. The most lesion found in the head CT-Scan
was multiple, with right hemispheric infarct as the majority affected area. Seven patient (53.8%) had
anticoagulant therapy a and all the patient who received therapy showed clinical improvement after
6 days, unless 1 patient who fail to assest due to not attendance at the subsequent visit.

Conclusion: Ischemic stroke in children is a rare disease. The incidence was 13 cases during 5 years
study period. The etiologic pattern was different with other country as theres no sickle cell anemia,
hemophilia, heart disease found in our study. Due to incomplete investigation, some etiology of
ischemic stroke remain unidentified.

KEY WORDS: stroke, childhood, etiology, clinical features, neuro-imaging.


Objective: To describe the incidence, neurological manifestations, neuro-imaging findings and the main
etiologies of ischemic stroke in children.

Method: Retrospective study of medical record was conducted of children who carried a diagnosis of
ischemic stroke from 2005-2010. Variables studied were sex, age at the time of episode, motor deficits,
presence of seizure, imaging findings, etiology, treatment and outcome.

Results: During 5 years periode, thirteen patients were diagnosed. Average age at presentation was 5.5
years. Six patients (46.2%) were female, and 7 patients (53.8%) were male. The most frequent
neurological deficit was left hemiparesis (38.5%). One patient had deafness as first manifestation. Only 4
patients (30.8%) experienced seizures. Coagulation disorder (69%) was the most frequent etiologies of
ischemic stroke in our patients, although there were 3 patients had unknown etiology due to incomplete
examinations. None of the patients had underlying disease like sickle cella anemia, moya-moya, heart
disease, and CNS infection. The most lesion found in the head CT-Scan was multiple, with right
hemispheric infarct as the majority affected area. Seven patient (53.8%) had anticoagulant therapy a
and all the patient who received therapy showed clinical improvement after 6 days, unless 1 patient
who fail to assest due to not attendance at the subsequent visit.

Conclusion: Ischemic stroke in children is a rare disease. The incidence was 13 cases during 5 years study
period. The etiologic pattern was different with other country as theres no sickle cell anemia,
hemophilia, heart disease found in our study. Due to incomplete investigation, some etiology of
ischemic stroke remain unidentified.

KEY WORDS: stroke, childhood, etiology, clinical features, neuro-imaging.