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The Transplant Imaginary 1 ‘ Mechanical Hearts, Animal Parts, and Moral ‘Thinking in Highly Experimental Science LESLEY A. SHARP B Hybrid Bodies and Animal Science The Promises of nerspecies rx ‘vat am. ain tev" -Whesthe oe™ andes 86)! From lay perspestive, entraspanation ra mex pealasclence. ui onthe premize that selene ingen could one day overcome the com plete ofthe human immune sate such that our bodies gh pereve foveig,animal-drved issue a self rather than “ther ths highly experimental domain deve by dsrs to aecomplsh embodied inter species hybrid In hopes of alleviating sfering and extending human Iie. Endessors to repsrthe brokenbodis fon ermal il patients are iewed as inherently moal~even heroic-goals within weno research Implantable parts ange om those derived at the molecular evel to whole ‘es organs where xenogtating could wel noe teterspeces an ‘er of pancrents sl cell, skin gts, and cade valves a well as kid reyes, ngs and hears For oer century xeno researchers have employed a ange of what thy currently relrence a donor” or “suree™ nialsinexperiaestal contents, Whereas, inthe uly ewertlth century, «ts, dogs, mc, and atic dominated experimen, by mié-entury other snimals reo prominence, namely primates (os noabychiespansecs| sndhaboons) and, more een pgs, eachtouted at varios ies ales matches for human bodies, Such speces preferences especialy where simian and porcine sources ae involved-are engender hy sckente ‘hin ae waders ane ene in sleee a local een tun they aon comps moral responses. Within eno spect ‘ly the magia of mor thinking inescapabyalected by the boner ‘owl vas asined to various species, by these and fupeton ofthe rts harested frm hem, andy the personal histones of alent whose Tvesthey migtoneday sve should the match rove immunology via- Ie Apesand monkey sully garner more pty than do pp the wse fa anima’ heart may tr stronger metal responses than, sa. kin grat, hormones ori lls; pela patientsare decmed worthy ogeater ssciioes than ae als titer the prime or en of thelr ves, Equally ‘pling the more vice restions expressed by poser patients Sd. even more iniguing, by ao cetiststhemsse when they ate {shed tomagine the consequences faving shy anil pars inpaned thin theism bails, ‘An andestaing that rests chap hat, within xenoslence il the furtilongngasiocnted wih certainty pesofanmas inspires ‘moa speculation, concern, and debate about eer evolving Hest about Ihuman/animal proximity. Thesyibele welt bores particular spe ‘esr even ust bay pats-inlormsdlscusons of xno socom ‘orth oth within ad beyond the laboratory. Animal mum presi In isnot udimentary farmiseten framed by notions kingredness Fan lin 2003, 2007; Taig 2009). have wetlen extenslyencertainaspets ‘of thistheme (Sharp 200th, 206-1; Sharp 2007, 7 108: Sharp ota. and sot toach nit ony bel ae he Kindred quien esq to chips Jongunderstsad sole voitonary “soins.” ely surace nthe ‘wayne setae andy these ad other nonhuman pe nae define cal matches rant: human organisers Ako ‘uch soning might well e viewed asa sce ft competing ap mens espoused by stil thers aout pgs reve the pronounced tos Invoe in tinaing delicate teresa brid 2 forma tans species hnsip. OF spl concern to me er, though how prximiy ‘ell may be approached as a moral eatgiry in xen, and ho this s Inxs ply y the rade sient useo animals. The theme o totes ‘se, expcily when ts roponent are faced with lime in athr quarters ‘hat various creates ae deserving of pel attention because thy ar danger andor Nighy nelligea this ight, xen scientists have ‘os certainly fund necessary to multe mal poslane with cre by marking on what Cela Lame 2004) esrb within the context ose ties conservation athe “making of [th] monkey” for scence, Ths “mak Ing” of anima appears even moe deliberate whee pigs ae concerned Xeno now steves to remake or refashion fr, perhaps even beter Pt, render) isso that they may be reimagined seven sprit simian a matches for buat Apes and monkeys figured prominently in ongoing tempts tans species wafting Between the mig andthe mil-99053 peri owe ‘ten celebrate as golden er of bold surgical etiot (Sharp 2011). The Seoade politics faxing sich highly sentent crestre, however, sub quently ed eno experts to set onthe pg asthe mort promising akerna- tive an approach rgnlly posited hy Sir Roy Calne, edi transplant expert ro the United King (Deschamps eal. 2005, 97: Calne, et: Sonal communication 201), Beasee my previous workonallotanplant ‘on bean formally in 90, and this cure project in 2008, my research as colpelded with what might be thought of 3 the ge ofthe pit? Never theless, when nthe company of xeno experts ela bear witness 10 ively dacusbone abou the compurstive values sine to primates and igs Whereas primate proximity ests squarely on evolutionary thinking out species kindedness (harp 20, agument that favo pgs ae

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