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PTH 746
Dr. Zipple
For this literature review I chose to look into what evidence-based research exists in
relation to the efficacy of segmental mobilizations. The question that I am trying to answer is
what evidence exists that supports the validity of segmental spinal mobilization treatments as
found and reviewed the article Does the choice of spinal level treated during posteroanterior
(PA) mobilization affect treatment outcome? After completing this article by Chiradejnant et al
I found that segmental spinal mobilization is superior to the globalized approach and should be
For this article the researchers focused on performing posteroanterior (PA) spinal
manipulative therapy (SMT) to treat patients with lower back pain (LBP) and non-specific lower
back pain (NSLBP). Chiradejnant et al focused on patients with LBP and NSLBP because of the
prevalence of both conditions in the general population. The researchers claim that 70% of
people experience LBP during their lifetime and between 10-50% of these patients will seek out
physical therapy (PT) to treat their condition. There are number of other treatments for LBP and
NSLBP that are used in PT such as: exercise therapy, massage, ergonomic advice and
electrotherapy. The researchers chose to ignore an eclectic approach using these alternative
treatments though and chose to focus on just PA SMT and its effects on spinal dysfunction.
Chiradejnant et al make the claim that the biomechanical effects of PA SMT on the body
are already well known and they are not researching this topic. The researchers state that the
biomechanical effects have been well researched, though not on patients with LBP. They
primarily have been researched on cadavers or cadaveric tissues that cannot display symptoms.
So even though the effects are well researched on the biomechanical end, the treatment outcomes
and efficacy of them are relatively un-researched. Chiradejnant et al cite a pair of researchers in
their studies who discovered that PA SMT create extension moments on the segment above and
flexion moments on the segment below the affected vertebrae. Applying the specific type of
flexion or extension moment through PA SMT to a patient with the matching restriction has
shown to improve the patients range of motion (ROM), decrease their pain levels and decrease
their disability.
While all of that is fine and dandy the efficacy and amount of improvements have not
been heavily researched. As it stands today, applying a passive accessory force to the most
affected vertebral segment is the proper way to treat patients with LBP or NSLBP. It is believed
that the physical therapist (PT) will achieve better results with this method as opposed to treating
adjacent segments or more remote segments with a globalized approach. With that said there is
little to no scientific evidence supporting this belief. So Chiradejnant et al created their study to
discover the efficacy of a treating the most asymptomatic vertebral segment with PA SMT as
The study was set up and conducted as a randomized controlled trial with a blind
outcome assessment. There was one PT who was responsible for treating all 120 subjects with
LBP at varying levels. Chiradejnant et al randomly split up the subjects into two groups. One
group would receive treatment to their most asymptomatic vertebral segment and the other
would receive a globalized treatment to a random segment. Baselines where established by the
PT for each individual patients level of pain and ROM. The PT recorded ROM for lumbar
flexion, extension and lateral flexion of each individual patient to identify their most restricted
motion. After the baselines where established an independent investigator was brought in to
record his own measurements of pain levels and ROM. After the investigator was finished he
exited the room and the PT then performed PA SMT at the predetermined level that was either at
the correct or random level unknown to the PT at the time of treatment. Immediately after each
individual treatment session the investigator was brought back in to record the post-intervention
After all of the data was gathered Chiradejnant et al found that significant differences
existed for each group. Within both groups there were significant differences between
preintervention and postintervention for both variables (pain levels, ROM). This proved that PA
SMT has an immediate effect on treating patients with LBP and NSLBP. Though of these
variables only the patients individual pain level was significantly reduced more when treatment
was applied to the correct (most asymptomatic) vertebral segment. On top of this discovery,
Chiradejnant et al also found that patients whose most restricted movement were lumbar flexion
had the greatest decrease in pain levels as compared to lumbar extension and lateral flexion.
This study found that PA SMT did in fact have a significant effect on treating patients
with LBP and NSLBP. Also that examining each patient to find their most asymptomatic
vertebral segment is very important because treating the most asymptomatic segment is the most
efficient method for using PA SMT. These results matched up well with the other articles that
Chiradejnant et al referenced and my own personal knowledge acquired from the Central
as compared to a globalized treatment protocol it did fall short in some aspects. This study only
examined the immediate effects of PA SMT on LBP and gives no indication of any short term,
intermediate or long term effects of this technique. So if a patient was to come into your clinic
with excruciating LBP you could give them almost instant relief but what would be the results
after they leave the clinic. This study only makes PA SMT comparable to short term analgesics
such as heating pads or pain relief medications. I believe that PA SMT performed at a higher
level through the use of more advance techniques is the most efficient way of treating LBP.
However, more research much be performed to determine the long term efficacy of using PA
SMT to treat patients with LBP. Once the long term efficacy is proven then PA SMT can be seen
1. Chiradejnant A, Latimer J, Maher CG, Stepkovitch N. Does the choice of spinal level
doi:10.1080/09593980290058544.