DRUG STUDY

DRUG ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES

Paracetamol Decreases fever by For body aches Known hypersensitivity to Skin: Rash Assess patients fever or pain: type of pain,
inhibiting the effects of Pains d/t common cold, paracetamol or other location, intensity, duration, temperature, and
Classification: pyrogens on the headache, backache, constituents in the tablets. Hematologic: Blood dyscrasias diaphoresis.
Analgesic, hypothalamus heat minor pain of arthritis, including thrombocytopenia, Assess allergic reactions: rash, uticaria; if these
antipyretic regulating centers and toothache, neutropenia, pancytopenia, occur, drug may have to be discontinued.
agent and by hypothalamic
premenstrual and
leukopenia and agranulocytosis, Teach patient to recognize sign of chronic
menstrual and overdose: bleeding, bruising, malaise, fever,
muscle action leading to menstrual cramps anemia, cyanosis
sore throat.
relaxants sweating and For fever Tell patient to notify prescriber for pain/ fever
vasodilation. CNS: Drowsiness, nausea, lasting for more than 3 days
Relieves pain by convulsion, coma
inhibiting
prostaglandin GI: Vomiting, abdominal pain
synthesis at the CNS
but does not have GU: hepatic seizure, renal failure
anti-inflamatory action
because of its minimal
effect on pheripheral
prostaglandin
synthesis.

DRUG ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES

IBUPROFEN May inhibit Management Contraindicate CNS: dizziness, Verify doctors order
prostaglandin in mild to d in patients headache, Observe 10 Rs

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synthesis, to moderate pain hypersensitive nervousness Prepare medication
produce anti- and to drug and in CV: edema, Inform the patient of
inflammatory, inflammation those with fluid retention the purpose of the drug
analgesic and in conditions angioedema, EENT: tinnitus Check renal and
antipyretic eg. syndrome of GI: abdominal hepatic function
effects. Dysmenorrhea, nasal polyps, pain, bloating, periodically in patients
headache or constipation, on long term therapy.
including bronchospatic decrease Blurred or diminished
migraine, reaction to appetite, vision and changes of
musculoskelet aspirin or other diarrhea, color vision may occur
al and joint NSAIDs. dyspepsia, Full anti-inflammatory
disorder. Contraindicate epigastric effects may intake 1 or
Reduction of d in in distress, 2 wks. to develop.
fever pregnant flatulence, Monitor sign and
woman. heartburn, symptoms of GI
Use cautiously nausea, no ulceration and bleeding.
in elderly necrotizing If pt. consume 3 or
patients and in enteroculitis, more alcoholic drinks
patients with vomiting per day, drug may
GI disorder, GU: acute cause stomach
hepatic or renal failure, bleeding.
renal failure, azotemia, Document the
hypertension cystitis, medication given
and asthma. hematuria Indicate time and site
HEMATOLOGY:
agranulocytosi
s, aplastic
anemia,
leukopenia,
neutropenia,
anemia,
prolonged
bleeding time
METABOLIC:
hyperkalemia,
hypoglycemia

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 SKIN: pruritus,
rush

DRUG ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES

MEDAZOLAM Bind receptor Pre-medication Hypersensitivit GI: nausea, vomiting Verify doctors order
at several sites before surgical y with NEUROLOGIC: Observe 10 Rs
CLASSIFICATIO within the procedure, midazolam hallucination, Prepare medication
N: sedatives CNS, including induction and Acute alcohol drowsiness, amnesic Inform the patient of
DOSAGE: 1mg the limbic maintenance intoxication the purpose of the drug
episodes
per ml system and of anesthesia. Monitor respiratory and
reticular CARDIO-
ROUTE: IV cardiovascular status
information. RESPOIRATORY:
FREQUENCY: Ensured safety
respiratory Advise not to ambulate
pre-op meds
depression of arrest 3 min. after
administration.
Document the
medication given.
Indicate time and
route.

DRUG ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES

NALBUPHINE Binds to Relief pain of Contraindicate CNS: dizziness, Verify doctors order
opioids moderate to d to patients headache, Observe 10 Rs
CLASSIFICATIO receptor in the severe pain hypersensitive sedation, Prepare medication
N: Opioid CNS, altering Also provides to drug. vertigo Inform the patient of
analgesic perception of sedation Use cautiously CV: the purpose of the drug
and emotional before surgery in patient with hypertension,

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 DOSAGE: 10 response to and severe renal, orthostatic, Evaluate patients
mg pain supplement to hepatic or hypotension, response to medication
ROUTE: IV balanced pulmonary palpitation Document the
FREQUENCY: anesthesia. disease and EENT: blurred medication given
every 4 hrs. hyperthyroidis vision, Indicate time and site
m. diplopia,
miosis
GI:
constipation,
dry mouth,
nausea and
vomiting
RESPIRATORY:
asthma
dyspnea
SKIN:
diaphoresis

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