1. During which metabolic stage is glucose broken down to pyruvate?
(A) Glycolysis (B) The citric acid cycle (C) The electron transport chain (D)Oxidative phosphorylation 2. What molecule is essential for aerobic respiration to take place? (A) Nitrogen (B) Oxygen (C) Ethanol (D)Carbon dioxide 3. Which of the following is not one of the three major macromolecule components of food? (A) Carbohydrates (B) Lipids (C) Oxygen (D)Proteins 4. Which of the following molecules contains three phosphate groups? (A) AMP (B) ADP (C) APP (D)ATP 5. Which of the following is not a coenzyme? (A) CoA (B) FAD (C) ATP (D)NAD 6. Organisms that acquire energy through photosynthesis are called which of the following? (A) Autotrophs (B) Chemotrophs (C) Prototrophs (D)Phototrophs 7. In which protein complex in the inner mitochondrial membrane is FADH2 oxidized? (A) I (B) II (C) III (D)V 8. Organisms that acquire energy through ingestion of food are called which of the following? (A) Autotrophs (B) Chemotrophs (C) Prototrophs (D)Phototrophs 9. Chemotrophs require _________ and produce _________ while phototrophs require _________ and produce _________. (A) Water, carbon dioxide, nitrogen, oxygen. (B) Oxygen, carbon dioxide, carbon dioxide, oxygen. (C) Oxygen, carbon dioxide, nitrogen, water. (D)Oxygen, water, phosphate, nitrogen 10.In which protein complex in the inner mitochondrial membrane is ATP synthesized? (A) I (B) II (C) IV (D)V 11.Metabolic reactions that synthesize molecules are classified as _________ while metabolic reactions that degrade molecules are classified as _________. (A) Chemotrophic (B) Phototrophic (C) Anabolic (D)Catabolic 12.What type of metabolic reaction involves a loss of electrons from the molecule involved? (A) Oxidation (B) Reduction (C) Phosphorylation (D)Isomerization 13.What molecule is produced when oxygen is reduced by the electrons in the electron transport chain? (A) Hydrogen (B) Water (C) NADH (D)FADH2 14.What type of metabolic reaction involves a gain of electrons by the molecule involved? (A) Oxidation (B) Reduction (C) Phosphorylation (D)Isomerization 15.How many molecules of carbon dioxide are generated during the citric acid cycle? (A) 1 (B) 2 (C) 3 (D)4 16.What type of metabolic reaction does not change the atomic make-up of the molecule involved? (A) Oxidation (B) Reduction (C) Phosphorylation (D)Isomerization 17.How many molecules of ATP can be generated from one round of the citric acid cycle? (A) 2 (B) 4 (C) 12 (D)24 18.What type of metabolic reaction involves the transfer of a phosphate group? (A) Oxidation (B) Reduction (C) Phosphorylation (D)Isomerization 19.Which of the following is not a component of the chemotrophic respiratory pathway? (A) Glycolysis (B) The citric acid cycle (C) Photosynthesis (D)Oxidative phosphorylation 20.What is the name of the molecule generated in the final step of the citric acid cycle and is also used in the first step? (A) Oxaloacetate (B) Pyruvate (C) Acetyl-CoA (D)NADH 21.Respiration that occurs without oxygen is classified as which of the following (A) Chemotrophic (B) Phototrophic (C) Aerobic (D)Anaerobic 22.What is the main cellular structure involved in respiration? (A) Nucleus (B) Golgi apparatus (C) Mitochondria (D)ER 23.Which of the following does not accurately describe the glycolytic pathway? (A) Anabolic (B) Catabolic (C) Chemotrophic (D)Metabolic 24.How many carbon atoms are found in one molecule of glucose? (A) 1 (B) 3 (C) 6 (D)9 25.What is the end product of aerobic glycolysis? (A) Citrate (B) Pyruvate (C) ATP (D)NADH 26.In what part of the cell does glycolysis take place? (A) Cytosol (B) Mitochondria (C) Golgi apparatus (D)ER 27.An enzyme that catalyzes a reaction that adds a phosphate group to a molecule is called which of the following? (A) Aldolase (B) Enolase (C) Kinase (D)Phosphorylase 28.In the second step of glycolysis, the enzyme phosphoglucose isomerase converts glucose-6- phosphate to fructose-6-phosphate. This reaction converts a ___-carbon molecule to a ___- carbon molecule. (A) 3,4 (B) 4,3 (C) 5,6 (D)6,5 29.What is the name of the glycolytic enzyme that converts dihydroxyacetone phosphate (DHAP) to glyceraldehyde-3-phosphate (GAP)? (A) Hexokinase (B) Triosphosphate isomerase (C) Aldolase (D)Enolase 30.Which of the following molecules is not either oxidized or reduced during electron flow through the electron transport chain? (A) NADH (B) FADH2 (C) Coenzyme A (D)Oxygen 31.How many molecules of ATP are produced during glycolysis (the net gain of ATP molecules)? (A) 2 (B) 4 (C) 12 (D)24 32.Which of the following atoms is involved in glycolytic reactions to shield negative charges? (A) Sodium (B) Oxygen (C) Magnesium (D)Phosphorous 33.Which of the following metabolic processes generates the most ATP? (A) Glycolysis (B) The citric acid cycle (C) The electron transport chain (D)Oxidative phosphorylation 34.What class of enzyme is involved in transferring a functional group from one position on a molecule to another? (A) Aldolase (B) Enolase (C) Kinase (D)Mutase 35.Where in an aerobic cell is NADH oxidized? (A) Cytosol (B) Mitochondria (C) Golgi apparatus (D)ER 36.Which of the following events do not take place in the mitochondria? (A) Glycolysis (B) The citric acid cycle (C) The electron transport chain (D)Oxidative phosphorylation 37.Which of the following is not a possible anaerobic glycolytic product? (A) Oxygen (B) Lactic acid (C) Ethanol (D)Carbon dioxide 38.Ethanol is a product of which of the following processes? (A) The citric acid cycle (B) Homolactic fermentation (C) Oxidative phosphorylation (D)Alcoholic fermentation 39.Which of the following is not a structural component of the mitochondria? (A) Matrix (B) Cytosol (C) Inner membrane (D)Intermembrane space 40.What is the starting material of the citric acid cycle? (A) Acetyl-CoA (B) Glucose (C) Pyruvate (D)NADH 41.Which stage in respiration produces the most coenzymes? (A) Glycolysis (B) The citric acid cycle (C) The electron transport chain (D)Oxidative phosphorylation 42.The outer mitochondrial membrane is highly _________ while the inner membrane is _________. (A) Permeable, impermeable (B) Impermeable, permeable (C) Charged, uncharged (D)Uncharged, charged 43.Which of the following does not accurately describe the citric acid cycle? (A) Amphibolic (B) Anabolic (C) Catabolic (D)Linear 44.Which of the following is not an enzyme that composes the pyruvate dehydrogenase multienzyme complex? (A) Pyruvate dehydrogenase (B) Phosphofructokinase (C) Dihydrolipoyl decarboxylase (D)Dihydrolipoyl transacetylase 45.Which of the following is not generated during the citric acid cycle? (A) GTP (B) NADH (C) Carbon dioxide (D)Pyruvate 46.Which of the following molecules does not freely cross the inner mitochondrial membrane? (A) Oxygen (B) Carbon dioxide (C) Pyruvate (D)Water 47.How many molecules of NADH are generated during the citric acid cycle? (A) 1 (B) 2 (C) 3 (D)4 48.How many molecules of FADH2 are generated during the citric acid cycle? (A) 1 (B) 2 (C) 3 (D)4 49.In which protein complex in the inner mitochondrial membrane is oxygen reduced? (A) I (B) II (C) III (D)IV 50.The coenzyme NAD/NADH is involved in which of the following types of reactions? (A) Elimination (B) Isomerization (C) Oxidation/reduction (D)Phosphorylation