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G.YUVARAJ M.Pharma.,Ph.

D
32/43 sundarm pillai street,Purasawalkam
Chennai PIN 600007 Tamil Nadu State, INDIA
Cell Phone: +91 9952968059
Email: moks.ra@gmail.com/yuvas2010@gmail.com
Career Objectives
To grow in Leadership and Knowledge – Infectious Disease, Cancer
Innovate, Develop and Apply world class solutions to real world challenges in th
e above three domains of Biology

CREDIT/Small age achievements:2 medicinal chemistry Internatioal journal exv edi


tor
77 International&32 national papers.
IJPSDR-Exev editor(International journal of Pharmacetical sciences&Drug research
-Medicinal/Phyto chemistry division
IJPCR-Editorial Board
Technical Skills and Experience

• Highly qualified Research Professional with 6 years of Teaching and Scie


ntific instrumentations, Administrative experience.
• Result oriented with the ability to proactively identify and provide sol
utions to research problems
areas of interest
• Pharmacokinetics and analytical chemistry.
• Clinical research –Bio analytical department.
• Pharmaceutical chemistry and drug development.

Domain knowledge contribution in interfacing LIMS and Analytical equipm


ents
Educational credentials

Ph.D –Thesis work ANALYTICAL &BIOPHARMACEUTICS,


CPGA-9.7 in Out of ten –Sanjivani Pharmacetical sciences(Chromosoft-Sponsor)
• JSS University, Ooty.India
M. Pharm- Gold medal student-medicinal chemistry
• Dr.MGR medical University, Chennai, India
B. Pharm (2 subject Gold medal)
• Small Industries Service Institute, Chennai, India

TRAINING ATTENED ON
GLP: “Basics of Good Laboratory Practice” held on 23rd January 2006. at
Chennai
GCP: “Good Clinical Practice” held on 5th February 2006. at
Bangalore
Quality Control Chemist, AST India Ltd,Jaipur.
Analysis of Active Pharmaceutical Ingredient (API) as per IP and
USP.
Anaysis the Pharmaceutical dosage form such as Tablet, Capsulses, Liquid
orals and Injections as per IP and USP.
Followed Good Laboratory Practise (GLP) analysis.

Professional Experience
SANJIVANI PHARMACETICAL SCIENCES,KHETRI-5 YRS EXP IN Team Leader IN BIO ANALYSIS
Chemistry/Clinical research Discovery
(2006 FEB-2010 APRIL)
APEX UNIVERSITY,JAIPUR-1 YR PRINCIPAL 2005 TO 2006 JAN-CHECK AICTE WEB
Technical skills and abilities
Molecular Modeling Using SYBYL 6.7 (Tripos,USA)
Comparative molecular field analysis (3-D QSAR) using
SYBYL 6.7 version
Organic and semi Syntheses.
Invivo and invitro antioxidant, Heptaoprotective, Antifertility anticanc
er
Knowledge in Method development and Method validation of bio analytical
methods using HPLC, UPLC and LCMSMS as per GLP and ICH guidelines.
Knowledge in Chromatographic principles with special emphasis on HPLC, U
PLC and LC-MS/MS.
Capability of investigating and applying new and existing techniques for
the efficient Bio analysis of drugs and drug metabolites.
Well versed in sample preparation techniques (Protein Precipitaion, Soli
d Phase extraction and Liquid-Liquid extraction) and Sample analysis.
Well versed with the design and usage of SOPs (Standard Operating Proced
ures) in my present job.
Calibration and Maintenance of various analytical instruments like HPLC,
UPLC, pH meter, analytical balances, micropipettes, etc. as per GLP.
Proficient in literature survey and interpretation of data.
Excellent communication and organizational skills and ability to work to
deadlines.
Ability to work independently and as part of a team.
Flexible approach within the working environment.
Ability to collaborate actively with many research groups in different f
ields and to initiate new contacts.
computer skills
All Microsoft office programs, including excel, PowerPoint and word.
Chemistry software packages including the ISIS Draw, Chem Draw.
Familiar in LIMS(laboratory information management systems).
E-LITERACY
Has Good Knowledge In MS WORD, MS EXCEL, MS POWERPOINT, SYSTEM BOOTING E
tc.
SYBYL 6.7 VERSION (TRIPOS- USA)J.S.S PHARMA
COMPUTER AIED MOLECULAR DESIGN(CAMD)
Conduct of Prestudy and Poststudy meeting

Responsibilities
• Leading the six member team in vitro anticancer department
• Cell bank Maintenance of 54 Human and Murine cancer cell lines
• Evaluation of New Molecular Entities for potential anti cancer activity
by means of
MTT assay for antiproliferative activity.
Assays for Apoptosis
Assays for Signal Transduction Pathways TNFά, IFNγ, IL6,pstat3NFKB,Bcl2
caspases.
Assay for the inhibition of Histone Deacetylase (HDAC) in both cell free and cel
l based systems
Syn enic and raft models for efficacy.
Pre clinical data mana ement for profilin the dru
Participatin member of phase forward of dru discovery and development

Dr. Siddique Gold Medal for the best article on Public Health entitled,
“Preliminary Report on the Seroprevalence of Japanese Encephalitis amon animal
s in Tamil Nadu” published in the Indian Veterinary Journal for the year 1999.
Dr. Krishnamoorthy Memorial Gold medal for the best Short communication
entitled “Enzyme linked Immunosorbent Assay for the detection of antibodies to C
anine Adenovirus Type-1” published in the Indian Veterinary journal for the year
1997.

Professional Membership

PROFESSIONAL MEMBERSHIP:
.Re istered Pharmacist in The Tamilnadu Pharmacy Council, Chennai.(UG&PG
)
Qualified in GATE examination.(M.Pharma-Merit student)
Instruments Known to handle
LCMS-API-2000, 3200, 4000, Sciex Applied Bio-Systems, Canada.
UPLC Waters Acquity, USA.
HPLC Waters Alliance-2695, USA.
HPLC, Shimadzu Prominence, Japan.
HPLC, A ilent 1100 and1200 series, USA.
FT-IR spectrometer, Perkin Elmer, USA.
UV-Vis Spectrophotometer, Jasco, India,
Probe Sonicator Vibra Cell, Sonics, USA.
Automatic nitro en evaporator, Turbo Vap LV, Zymax corp. USA.

PROJECTS HANDLED
Title: Synthesis Of pyrazoline derivative(Anti tumour/Antian io esis) And QSAR S
tudies Includin CoMFA (3-D QSAR) Of Some Possessin New Chemical Entities
Medicinal Plants in Kollimalais-A Survey.
Comparative studies on Hydroxy propyl methyl cellulose, uar um and um
karaya matrix tablets formulated with diclo fenac sodium
STRENGTHS
Capable of workin in a fully computerized environment
Dynamic Personality, dedicated amicable relationship and stron desire t
owards learnin with mana ement.
Hard workin and ood team player.
Self Or anized, ood interpersonal and communication skills.
Personal Information

Name in full (as per Passport): G.Yuvaraj


Passport Details: B3670318
Pharmacy Council Re istration Number: 4834 A1
Father’s Name: P.Govindarajan
Mother’s Name: G.Kalavathy
Date of Birth: 23-04-1980
Place of Birth: Chennai, Tamil Nadu, India.
Sex: Male
Marital Status: Married
Nationality: Indian

PUBLICATIONS
Puplication
1) Bharkatiya M and yuvaraj G Desi nin and Evaluation of Nimesulide Transd
ermal Patches, Int. J. Pharmaceutics, 1(1), 46-51(2006).
2) Patel D, Tanwar YS, Naruka PS and Yuvaraj G, Polymeric Occular Dru Deli
very System for Controlled Release of Ofloxacin: in-vitro and in-vivo Characteri
zation, The Pharma Review, 125-128(2007).
3) Samanta S, Mandal S and Yuvaraj G, Synthesis of Some Smaller Chain Cycli
c Peptides and Their Antidiabetic Studies Throu h Injectable and Oral Route Admi
nistration, Int. J. Chem. Sci.,5(1),423-433(2007).
4) Sin h HP, Sin h A and Yuvaraj G, Synthesis, Biolo ical evaluation, Insil
ico metabolism and Toxicity production of Piperidine derivatives (2007) Communic
ated.
5) Sin h HP, Sin h A and Yuvaraj G, QSAR studies of pyridazine derivatives
as tuberculostatic a ents (2007) Communicated.
Sin h HP, Sin h A and Yuvaraj G, QSAR study of substituted anthracenones derivat
ives as inhibitors of 12- lipoxy enase enzymes (2007) Communicated

Presentation-seminar
1. yuvaraj, Mathur M, Sonie KK and Ramawat KG, Bioactive polyphenolics and
bulbils formation in Curculi o orchioides shake flask cultures. Poster presentat
ion in Jaipur,2005.
2. Rathore KS and yuvaraj, Development of Successful Controlled Release Dos
a e Forms for Opthalmic Dru Delivery System, AICTE Sponsored National Level Sam
inar on Recent Trends in Innovative Dru Discovery and Research, 34-35, Oct.27-2
9, 2006.
3. Rathore RPS and yuvaraj, Influence of the Concentration of Gellin A ent
s on the Rheolo ical Properties of Gels, AICTE Sponsored National Level Saminar
on Recent Trends in Innovative Dru Discovery and Research, 36, Oct.27-29, 2006.
4. Rathore RPS, Nema RK, Gupta GD and yuvaraj, Effect of PVP on Transdermal
Delivery of Terbutaline Sulphate, AICTE Sponsored National Level Saminar on “Re
cent Trends in Innovative Dru Discovery and Research” 37, Oct.27-29, 2006.
Vision:

In the phase of advancin technolo y in combinatorial synthesis and HTS,the dru


discovery process continues to evolve. Preclinical dru metabolism & PK studies
play a key role in lead identification

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