Hasil control dr. Sp.

S di RSPI

Kondisi pasien dengan Post-meningitis dapat meninggalkan sekuele (gejala sisa)

yang mana bisa mengakibatkan kecacatan permanen. Sehingga untuk pasien Lisa,
sekuelenya berupa kejang dan keterlambatan fisik dan mental, namun dengan obat-
obatan yang telah diberikan gejjala kejang sudah mulai berkurang, untuk itu pasien
hanya memerlukan perhatian dari orang tua untuk mendukung pasien dalam
tumbuh kembangnya dalam kondisi yang terbatas ini. Keluarga juga harus dapat
memantau pengobatan pasien.

Journal review of Meningitis Sequelae

Predictors of Long Term Neurological Outcome in Bacterial Meningitis

Pratibha Singhi, Arun Bansal, P. Geeta and Sunit Singhi
Department of Pediatrics, Postgraduate Institute of Medical Education and
Research, Chandigarh.

[Received June 26, 2006; Accepted November 1, 2006]

The authors' have found that the overall prevalence of neurological sequelae among
the survivors of acute bacterial meningitis was 40% and of major sequelae 30%.
The spectrum of neurological sequelae in their patients was similar to that reported
in other studies viz, sensorineural hearing loss, motor problems, seizures and
mental retardation. Most common neurological sequelae seen in the present study
was severe mental retardation (21%).

Bacterial meningitis and epilepsy

Jagaralapudi Murali K. Murthy and Sudesh Prabhakar

Department of Neurology, The Institute of Neurological Sciences, CARE

Hospital, Hyderabad, India; and Department of Neurology, Post Graduate
Institute of Medical Education and Research, Chandigarh, India

Epilepsia, 49(Suppl. 6):812, 2008

The majority of unprovoked seizures following bacterial meningitis occur within 5

years of the acute illness (de Graaf, 1974; Bergamini et al., 1977; Sell et al., 1977;
Rantakallio et al., 1986; Annegers et al., 1988; Pomeroy et al., 1990; Chang et al.,
2004). Unprovoked seizures following bacterial meningitis tend to be recurrent
(Rosman et al., 1985; Annegers et al., 1988; Pomeroy et al., 1990).
There are virtually no data on the long-term prognosis of epilepsy associated with
bacterial meningitis. Remission rates following antiepileptic drug therapy are
perhaps similar to other epilepsies with remote symptomatic etiology, i.e., 50%
(Pomeroy et al., 1990). Patients with medically refractory, localization-related
epilepsy and prior history of meningitis often have underlying mesial temporal
sclero-

sis. In such cases, if imaging reveals unilateral hippocampal sclerosis, the seizure
outcome following surgery (anterior temporal lobectomy) is good (Marks et al.,
1992; OBrien et al., 2002).

Long term neurological complications of bacterial meningitis in Nigerian

children
Frank-Briggs AI Alikor EAD
Department of Pediatrics & Child Health University of Port-Harcourt
Teaching Hospital,
Port-Harcourt, Nigeria
2013

In the study the under fives were mainly affected with post meningitis neurologic
complication. This is similar to other reports.7, 9 This age bracket heralds the period
of maximal brain development and any assault or insult to the developing brain
results in neurophysiologic sequelae. Twenty eight (29.79%) of children with long
term complications presented with recurrent seizure disorder. This is similar to other
studies where seizures occur in 20 to 30 percent of children with acute bacterial
meningitis. 2, 10 The pathogenesis of seizures in meningitis is not well understood.
Although fever may be a cofactor in very young children, cerebrovascular
inflammation or secondary neurochemical changes are presumably the cause of
most seizures. Seizures that occur early in the course of bacterial meningitis are
easily controlled and are rarely associated with permanent or long term neurologic
complications. In contrast, seizures that are prolonged, difficult to control, or begin
more than 72 hours after hospitalization are more likely to be associated with
neurologic sequelae, suggesting that a cerebrovascular complication may have
occurred. 2, 4,9,11 In our study 5.38% of the children had a significant motor
impairment that presented as hemiparesis / hemiplegia. This is a focal neurologic
complication of bacterial meningitis which is devastating to the affected children
and caregivers.