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Syarat biomaterials:
Biokompatibel
Memiliki sifat mekanis yang tinggi
Tahan korosi
Polymeric biomaterials
Bioceramics
Metallic biomaterials
Biocomposite
Jenis-jenis Biomaterials
Jenis-jenis Biomaterials (lanjutan)
Polymer Biomaterials
APPLICATION of
Polymeric Biomaterial
Contact
Lens
bone
plates
Nose implants
Biodegradable
stent knee & hip replacement
2. Design Device: Total Hip Replacement
3. Biomaterial Selection
BIODEGRADABLE STENTS
Stent: inserted into a blocked artery to improve blood flow
Biodegradable Stent
Biodegradable Polymer Stents:
Present long enough for vessel to
re-model and then it dissolves
Can be drug-loaded
Minimize restenosis
Disadvantage: recoil (weaker than SS)
BIODEGRADABLE ORTHOPEDIC DEVICES
Degradation
Tg cryst. modulus Time (months)
O
Poly(L-lactic acid) O CH C 60 C 40 % 2.7 GPa > 24
PLLA n
CH3
Mechanical Properties of Biomaterials
Replacing permanent metallic devices with biodegradable polymeric
devices is desirable but limited by polymers lower mechanical properties.
Elastic Modulus
Cancellous bone ~5 GPa
Cortical Bone 17-27 GPa
Stainless Steel 200 GPa
PLLA 2.7 GPa
Metallic biomaterials
Metals and its alloys widely used as
biomaterial because:
Strong material
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Metallic Biomaterials
Metallic Biomaterials
Metallic Biomaterials
Advantages disadvantages
High strength
High moduls
Fatigue resistance
Corrosion
Wear resistance
Metal ion sensitivity
Easy fabrication and toxicity
Easy to sterilize Metallic looking
Shape memory
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Metallic material usually used in
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Metal used in Biomedical
Restorative dental
composites
CF = carbon fiber;
PEEK = Polyether ether ketone
Bicomposites
BIODEGRADABLE MATERIALS