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Pharmaceuticals
Drug Threat Assessment
Product No. 2004-L0487-001 November 2004
Pharmaceuticals
Drug Threat Assessment
Table of Contents
Key Findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Abuse . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Availability . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4
Diversion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4
Doctor Shopping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
Prescription Fraud . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
Unscrupulous Physicians . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
Theft . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
Internet Pharmacies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8
Northeast Region. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
Southeast Region. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11
Midwest Region. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12
Southwest Region . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13
Pacific Region . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15
West Region . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16
Outlook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
Sources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19
Pharmaceuticals
Drug Threat Assessment
Key Findings
Abuse of prescription drugs increased sharply Pharmaceuticals pose an increasing threat to
through the 1990s, appears to have stabilized by the United States. National Drug Intelligence
2002, and may now be declining. Emergency Center (NDIC) National Drug Threat Survey
department mentions of narcotic analgesics (NDTS) data (see text box on page 2) indicate
increased more than 160 percent from 1995 that the percentage of state and local law enforce-
through 2002, and those of benzodiazepines ment respondents that identify pharmaceuticals as
increased 40 percent during the same period. their greatest drug threat increased from 2.4 percent
From 1992 through 2002, treatment admissions in 2003 to 3.1 percent in 2004.
for opiates other than heroin increased more than The threat posed by pharmaceuticals varies by
200 percent. region. Law enforcement agencies in the North-
The availability of pharmaceuticals has east, Southeast, and Midwest regions were more
increased since the late 1990s when legitimate likely to identify pharmaceuticals as their greatest
production of pharmaceuticals increased sharply, drug threat than agencies in the Southwest,
making more pharmaceuticals available for ille- Pacific, and West.
gal diversion.
Overview
The diversion and abuse of pharmaceutical The availability of pharmaceuticals has
narcotics, depressants, and stimulants are a sig- increased since the late 1990s. Legitimate com-
nificant threat to the United States. A review of mercial production and disbursals of pharmaceuti-
the most recent national-level drug prevalence cals, particularly prescription narcotics, have
studies indicates that rates of abuse for prescrip- increased sharply since the late 1990s, making
tion drugs have increased sharply since the early more of the drugs available for illegal diversion.
to mid-1990s but appear to be stabilizing at high Most pharmaceutical controlled substances abused
levels. The consequences of prescription drug in the United States are diverted by forged pre-
abuse also have increased since the early to mid- scriptions, “doctor shopping,” and theft; however,
1990s and have continued to increase during the law enforcement agencies report that diversion of
past 2 reporting years. pharmaceuticals via the Internet, often through
Internet-based pharmacies, has increased sharply West (0.0%) regions. Similarly, only 2.5 percent
since the mid- to late 1990s. of state and local law enforcement agencies
Although most law enforcement agencies are nationwide report that pharmaceuticals are the
concerned about diversion and abuse of pharma- drugs that most contribute to property crime in
ceuticals, national-level drug survey data show their areas—higher than MDMA (0.1%) but much
that only a small percentage of state and local law lower than crack (35.6%), methamphetamine
enforcement agencies report that pharmaceuticals (32.7%), heroin (12.3%), marijuana (9.5%), and
are the greatest drug threat to their areas. How- powdered cocaine (5.2%). Regionally, a higher
ever, that percentage may be increasing. NDTS percentage of agencies in the Northeast region
2004 data indicate that 3.1 percent of state and (4.4%) report that pharmaceuticals are the drugs
local law enforcement agencies nationwide iden- that most contribute to property crime in their
tified pharmaceuticals as their greatest drug areas than agencies in the Southeast (3.0%), Mid-
threat, up from 2.4 percent in 2003. Regionally, west (2.2%), Pacific (0.7%), Southwest (0.3%), or
more state and local law enforcement agencies in West (0.2%) regions.
the Northeast (4.9%), Southeast (4.0%), and Mid- National Drug Threat Survey 2004
west (3.2%) identify pharmaceuticals as their
NDTS 2004 was administered by NDIC to a
greatest drug threat than agencies in the South- representative sample of state and local law
west (0.3%), Pacific (0.2%), and West (0.0%) enforcement agencies throughout the United
regions. States to assess the availability and overall
Despite a demonstrable rise in pharmaceutical threat posed by the trafficking and abuse of all
drug abuse since the mid- to late 1990s, NDTS major drug types. NDIC received 3,429 survey
data indicate that less violent or property crime is responses from law enforcement agencies, an
associated with pharmaceuticals than with most overall response rate of 98.4 percent. Survey
respondents were asked to indicate the drug
other drugs of abuse. NDTS 2004 data indicate
that posed the greatest threat to their areas
that only 2.2 percent of state and local law and to indicate the level of availability for each
enforcement agencies nationwide report that phar- major drug type. Respondents also were
maceuticals are the drugs that most contribute to asked to indicate the drug type that most con-
violent crime in their areas—higher than MDMA tributes to property crimes and violent crimes
(0.2%) but much lower than crack (40.7%), meth- within their jurisdictions. Responding agencies
amphetamine (34.2%), powdered cocaine (7.7%), also were asked to indicate the level of street
heroin (5.8%), and marijuana (4.6%). Regionally, gang and outlaw motorcycle gang (OMG)
a higher percentage of agencies in the Northeast involvement in drug distribution in their areas.
region (4.0%) report that pharmaceuticals are the Survey responses are used by NDIC to sub-
drugs that most contribute to violent crime in their stantiate and augment drug threat information
areas than agencies in the Midwest (2.6%), South- obtained from other federal, state, and local
east (2.0%), Southwest (0.3%), Pacific (0.2%), or law enforcement agencies.
Abuse
Nationwide, the rate of abuse for pharmaceu- illicit and prescription methamphetamine), or
ticals is relatively high compared with rates of sedative (not including over-the-counter drugs) in
abuse for other drug types. National Survey on 2003, second only to marijuana (10.6%) and
Drug Use and Health (NSDUH) data indicate that much higher than cocaine (2.5%) and heroin
6.3 percent of persons aged 12 or older reported (0.1%). These rates are similar to those in 2002
nonmedical use of any prescription-type pain when 6.2 percent of persons aged 12 and older
reliever, tranquilizer, stimulant (including both reported nonmedical use of any prescription pain
reliever, tranquilizer, stimulant, or sedative within show that past year nonmedical use of tranquiliz-
the past year, second only again to marijuana ers was unchanged from 2002 to 2003 for those
(11.0%) and much higher than cocaine (2.5%) aged 12 to 17 (2.3% in both years) and 26 or
and heroin (0.2%). older (1.5% in both years); the change in rates for
Monitoring the Future (MTF) data indicate those aged 18 to 25 (4.9% to 5.3%) was not sig-
that rates of abuse for “other narcotics”— nificant. NSDUH data further show that past year
prescription narcotics such as hydrocodone nonmedical use of sedatives was quite stable from
(Vicodin), oxycodone (OxyContin), hydromor- 2002 to 2003 for those aged 12 to 17 (0.6% and
phone (Dilaudid), and codeine—have increased 0.5%, respectively), 18 to 25 (0.5% in both
over the past decade. According to MTF, the rate years), and 26 or older (0.4% and 0.3%).
of past year abuse for prescription narcotics has Very limited national-level data regarding
increased among twelfth graders from 3.3 percent abuse of prescription stimulants, particularly
in 1992, to 6.2 percent in 1997, to 9.4 percent in Ritalin (methylphenidate), indicate that rates of
2002, but remained relatively stable at 9.3 percent abuse are declining. Past year rates of abuse for
in 2003. Among young adults (aged 19 to 28), the Ritalin have been tracked only since 2001;
rate of past year abuse for prescription narcotics however, the data indicate an overall decrease
steadily increased each year between 1992 (2.5%) from 2001 to 2003 among eighth (2.9% to 2.6%),
and 2001 (5.0%), but significantly increased in tenth (4.8% to 4.1%), and twelfth (5.1% to 4.0%)
2002 (7.1%) and 2003 (8.5%). NSDUH data graders. MTF data show that the rate of past year
show that past year nonmedical use of pain abuse of Ritalin among young adults was 2.9 per-
relievers was relatively stable from 2002 to 2003 cent in both 2002 and 2003. NSDUH data show
for those aged 12 to 17 (7.6% and 7.7%, respec- that past year nonmedical use of stimulants
tively), 18 to 25 (11.4% and 12.0%), and 26 or (includes methamphetamine) was relatively sta-
older (3.1% and 3.3%). ble from 2002 to 2003 for those aged 12 to 17
According to MTF, the rates of past year (2.6% and 2.3%, respectively), 18 to 25 (3.7%
abuse of prescription depressants have increased and 3.5%), and 26 or older (0.8% and 0.6%).
overall since 1992. MTF data for 2003 show that Emergency department (ED) and treatment
rates of past year abuse for prescription tranquil- data indicate that the consequences of prescrip-
izers such as Xanax and Valium have increased tion drug abuse have increased overall since the
among twelfth graders from 2.8 percent in 1992, early to mid-1990s, with the exception of meth-
to 5.5 percent in 1998, to 7.7 percent in 2002, but ylphenidate (Ritalin). Drug Abuse Warning Net-
then decreased to 6.7 percent in 2003. Among work (DAWN) data reveal that the number of ED
young adults (aged 19 to 28), the rate of past year mentions for “Narcotic Analgesics” increased
abuse for prescription tranquilizers has increased steadily from 1995 (20,910), to 1998 (32,573), to
from 3.4 percent in 1992, to 3.8 percent in 1998, 2001 (64,786), and then increased an additional
to 7.0 percent in 2002, but remained relatively 25 percent from 2001 to 2002 (64,786 to 81,002).
stable at 6.8 percent in 2003. MTF data also indi- Similarly, DAWN data show steady increases in
cate an overall increase in the rate of past year the number of ED mentions for benzodiazepines
abuse for prescription sedatives (barbiturates) from 1995 (76,548), to 1998 (88,808), to 2001
among twelfth graders from 2.8 percent in 1992, (103, 972). The number of ED mentions for this
to 5.5 percent in 1998, to 6.7 percent in 2002, but drug category increased by 2 percent (103,972 to
then decreased somewhat to 6.0 percent in 2003. 105,752) from 2001 to 2002—the smallest year-
The rate of past year abuse of prescription seda- to-year increase since the 1998–1999 period
tives also has increased among young adults from (88,808 to 90,539, respectively). The estimated
1.6 percent in 1992, to 2.5 percent in 1998, to 3.9 number of ED mentions for methylphenidate has
percent in both 2002 and 2003. NSDUH data decreased steadily from 1,860 in 1995, to 1,728 in
1998, to 1,279 in 2001 and declined again, albeit (prescription narcotics and opium) increased from
only slightly, to 1,245 in 2002. 13,671 in 1992, to 16,121 in 1995, to 19,941 in
The most recently available data from the 1998, to 29,064 in 2000, to 45,605 in 2002, the
Treatment Episode Data Set (TEDS) indicate that most recent year for which such data are available.
the number of admissions to publicly funded drug The number of admissions for benzodiazepines
treatment facilities for prescription drug abuse has also has increased steadily from 1992 (2,882), to
increased steadily since 1992. For example, the 1995 (3,222), to 1998 (4,524), to 2002 (7,226).
number of admissions for “Other Opiates”
Availability
There are no conclusive estimates as to the decreased 27.4 percent from 2000 (454,301 g), to
total amount of diverted prescription narcotics, 2001 (407,625 g), to 2002 (375,155 g), to 2003
depressants, and stimulants available in domestic (329,792 g). Similar data are not available for
drug markets. However, data regarding legitimate depressants or stimulants.
commercial disbursal of prescription pharmaceuti- Wide-ranging law enforcement reporting
cals indicate that the amount of prescription drugs indicates that the availability of diverted pharma-
disbursed to pharmacies, hospitals, practitioners, ceuticals has increased over the past 3 years, an
and teaching institutions has increased sharply assertion supported by national-level drug survey
over the past 4 years, thereby rendering more of data. NDTS 2004 data reveal that the percentage
these drugs available for diversion. According to of state and local law enforcement respondents
the Drug Enforcement Administration (DEA), reporting high or moderate availability of diverted
pharmaceutical drug disbursals have increased pharmaceuticals increased from 70.0 percent in
overall since 2000, particularly for OxyContin. In 2002, to 72.3 percent in 2003, to 75.6 percent in
fact, OxyContin appears to be supplanting other 2004. NDTS 2004 data further indicate that 17.8
prescription narcotics such as Percodan and percent of state and local law enforcement agen-
Lortab. OxyContin disbursals (in grams) increased cies report that the availability of diverted phar-
from 2000 (10,415,575 g), to 2001 (14,002,125 g) maceuticals is low, and only 3.6 percent report
to 2002 (15,118,153 g), to 2003 (16,982,548 g)—a that diverted pharmaceuticals are not available in
63.0 percent increase from 2000 to 2003. During their areas.
that same period Percodan and Lortab disbursals
Diversion
Most pharmaceuticals abused in the United by pharmacies and physicians to suspected abus-
States are diverted by doctor shopping, forged ers. For example, the Kentucky Cabinet for
prescriptions, theft and, increasingly, via the Health Service reports that the Kentucky All
Internet. To reduce the occurrence of pharmaceu- Schedule Prescription Electronic Reporting
tical diversion by doctor shopping and prescrip- (KASPER) system has reduced the average time
tion fraud, 21 states have established prescription to complete pharmaceutical drug investigations
monitoring programs (PMPs) that facilitate the from 156 to 16 days. Moreover, according to the
collection, analysis, and reporting of information Office of National Drug Control Policy
regarding pharmaceutical drug prescriptions. (ONDCP), establishment of the Nevada PMP has
State-level PMPs have been effective in reducing resulted in a 46 percent reduction in the estimated
the average time required to conduct pharmaceu- number of pharmaceutical dosage units distrib-
tical diversion investigations as well as reducing uted to suspected abusers.
the estimated number of dosage units dispensed
Doctor Shopping
Prescription Fraud
Unscrupulous Physicians
Illegal prescribing by unscrupulous physi- without a legitimate need for the drug for a fee.
cians is a significant source of diverted pharma- Unscrupulous physicians sometimes collaborate
ceuticals. Corrupt physicians create fraudulent with unscrupulous pharmacists who dispense the
prescriptions to obtain drugs for personal use, and drugs for an additional fee.
they also write prescriptions for individuals
Theft
Millions of pharmaceutical drug dosage units University of Florida, retailers attribute 48 per-
are diverted each year through theft from pharma- cent of pharmaceutical inventory loss to
cies, manufacturers, distributors, importers/ employee theft. Individuals also break into phar-
exporters, and from individuals with legitimate macies or clinics to steal pharmaceuticals or
prescriptions. The amount of pharmaceutical dos- commit armed robberies to acquire the drugs.
age units diverted annually from 2000 to 2003 Individuals also steal pharmaceuticals from
through theft fluctuates but has increased overall friends or relatives who possess legitimate
for most drugs, particularly for prescription nar- prescriptions.
cotics like OxyContin. According to DEA, the Pharmacy managers and law enforcement
number of pharmaceutical dosage units diverted agencies in areas that have experienced a high
through theft from pharmacies, manufacturers, number of pharmacy break-ins and armed
distributors, and importers/exporters has increased robberies have taken specific steps to reduce
from 2,379,389 in 2000 to 2,753,928 in 2003. pharmaceutical theft. For example, many pharma-
Employees of pharmaceutical drug manufac- cies have stopped distributing specific pharma-
turers and commercial distributors account for ceuticals that thieves most often target, such as
much of the pharmaceuticals diverted through OxyContin. Law enforcement in some communi-
theft; however, others steal pharmaceuticals as ties, such as Boston (MA) and Pikeville (KY),
well. According to the 2002 National Retail have increased patrols in and around pharmacies
Security Survey Final Report published by the to deter or detect break-ins and robberies.
Internet Pharmacies
Pharmaceuticals increasingly are diverted via followed by narcotic analgesics such as fentanyl,
the Internet because many Internet pharmaceutical hydrocodone, and oxycodone, and stimulants such
distributors—often referred to as Internet pharma- as Ritalin and Adderall. Moreover, none of the 157
cies—offer prescription drugs to customers with- Internets sites included security procedures pre-
out requiring a prescription, physician consulta- venting children from purchasing prescription
tion, or verification. Estimates as to the number of drugs.
Internet pharmacies vary widely. For example, the
National Board of Pharmacy estimates that the Internet Pharmacy Ring Indicted
number of Internet pharmacies has increased from On December 29, 2003, the Federal Bureau of
none in the mid- to late 1990s to between 400 and Investigation (FBI) announced that a 108-count
1,000 in 2003. However, in January 2004 the indictment was unsealed against 3 companies
National Center on Addiction and Substance and 10 individuals across the country. Together,
they allegedly set up a massive Internet phar-
Abuse (CASA) identified only 157 Internet sites
macy ring that used dozens of web sites like
distributing controlled pharmaceuticals to individ- www.get-it-on.com to hawk dangerous and
ual users, although an additional 338 Internet sites addictive drugs without the medical supervision
provided links to one or several of the 157 pharma- required by law. In the process, they dispensed
ceutical distribution sites. Nevertheless, of the 157 millions of dosage units of drugs and made
Internet sites identified by CASA, 64 (40.7%) did more than $150 million. A doctor, who ulti-
not require any prescription or physician consulta- mately pled guilty in the case, authorized more
tion to purchase prescription drugs. Moreover, 77 than 22,000 prescriptions yet never met with a
(49.0%) of the Internet sites only required custom- single patient, performed an exam, took a
ers to report their symptoms in an online question- patient history, or verified medical information
naire prior to receiving the prescription drug— provided. A pharmacist, who also pled guilty,
there was no requirement for personal physician ran a pharmacy in Virginia and dispensed more
verification of the symptoms. Faxed prescriptions than 2.5 million pills yet knew that the custom-
ers’ identities had not been verified and that
were required by 7 (4.4%) and mailed prescrip-
some customers were buying massive
tions were required by 3 (1.9%) of the sites. The amounts of drugs. Because so many prescrip-
remaining 6 (3.8%) sites made no reference to any tions were filled, the pharmacist often did not
prescription requirement. CASA further reports even have time to prepare and review them all.
that the Internet pharmacy sites most often offered
Source: Federal Bureau of Investigation.
benzodiazepines such as Xanax and Valium,
FBI reporting indicates that many unscrupu- occurrences of distribution of counterfeit pharma-
lous Internet pharmacy operators recruit corrupt ceuticals in the United States are increasing. As a
physicians to write fraudulent prescriptions for result, FDA counterfeit drug investigations have
their customers. FBI further reports that unscru- increased from 6 in 1997 to 22 in 2003.
pulous physicians are paid as much as $1,500 per
day for writing fraudulent prescriptions for Inter- 25
net pharmacy patients.
20 22 22
Some Internet pharmacies, including some 20
based in Mexico and Canada, distribute counter-
feits of popular brand name pharmaceuticals that 15
Number
often contain inactive ingredients, incorrect
ingredients, or improper dosages. According to 10
FBI, most counterfeit pharmaceuticals are pro-
duced in India and China, and in some countries
5 6 6 6
counterfeit pharmaceuticals are quite prevalent.
4
In fact, FBI reporting indicates that as much as 60
percent of the pharmaceuticals sold in China, 0
1997 1998 1999 2000 2001 2002 2003
Nigeria, Thailand, Cambodia, and Indonesia are Year
counterfeit. The Food and Drug Administration Figure 1. Counterfeit Drug Cases, 1997–2003.
(FDA) reports that the level of counterfeit drug Source: U.S. Food and Drug Administration.
distribution within the United States is very low
compared with other countries; however,
Northeast Region
According to NDTS 2004 data, a higher per- (7.8%) report that hydromorphones are com-
centage of state and local law enforcement monly diverted and abused in their areas.
respondents in the Northeast region identify phar- Regional drug prevalence data are not avail-
maceuticals as their greatest drug threat (4.9%) able; however, drug consequence data show
than agencies in any other region of the country. increases in the number of ED mentions and
In addition, NDTS data show that 4 percent of treatment admissions for prescription narcotics.
state and local law enforcement agencies identify DAWN data indicate that the combined number
pharmaceuticals as the drugs that most contribute of ED mentions for “Narcotic Analgesics” (pre-
to violent crime, while 4.4 percent report that scription narcotics) for the seven DAWN report-
pharmaceuticals are the drugs that contribute ing cities in the Northeast region (Baltimore,
most to property crime in their areas. Boston, Buffalo, District of Columbia, Newark,
The diversion and abuse of prescription nar- New York City, and Philadelphia) increased
cotics such as oxycodones (OxyContin, Percocet, sharply and steadily from 2000 (8,842 men-
and Percodan), hydrocodones (Lorcet and Vico- tions), to 2001 (12,289 mentions), to 2002
din) and, to a lesser extent, hydromorphones (15,944 mentions). Furthermore, TEDS data
(Dilaudid) are significant and increasing threats show that admissions to publicly funded treat-
to the Northeast region. NDTS 2004 data indicate ment facilities in the Northeast region for “Other
that a high percentage of state and local law Opiates” (nonheroin opiates/synthetics) also
enforcement agencies in the Northeast region increased sharply from 2000 (9,317 admissions),
report that oxycodones (72.6%) and hydrocodones to 2001 (11,971 admissions), to 2002 (15,684
(50.7%) are commonly diverted and abused in admissions), the most recent year for which data
their areas. A smaller percentage of agencies are available.
Southeast Region
NDTS 2004 data reveal that 4.0 percent of
Traffic Stop in Alabama Results in
state and local law enforcement agencies in the
Large Seizure of Hydrocodone
Southeast identify diverted pharmaceuticals as
their greatest drug threat. Survey data also indi- On March 11, 2004, officers with the Harpsville
(AL) Police Department seized 3,957 grams
cate that 2.0 percent of southeastern state and
(approximately 9,000 dosage units) of hydro-
local law enforcement agencies report that phar- codone during a traffic stop on U.S. Highway
maceuticals are the drugs that most contribute to 280 in Harpsville. According to officials, the
violent crime in their areas, while 3.0 percent officers stopped a minivan for an improper lane
report that pharmaceuticals contribute most to change. After routine questioning of the driver,
property crime. Despite the relatively small per- a 54-year-old male, officers requested and
centage of law enforcement agencies in the received consent to search the vehicle. During
Southeast region that identify pharmaceuticals as the search, officers discovered the hydro-
their greatest drug threat, diversion and abuse of codone in three bags, which were taped
such drugs are common. together and concealed under paint supplies in
the cargo area of the van. The driver was
The diversion and abuse of prescription nar- arrested and charged with felony unlawful pos-
cotics such as oxycodones (OxyContin, Percocet, session of a controlled substance. Evidence in
and Percodan), hydrocodones (Lorcet and Vico- the vehicle indicated that the driver had
din) and, to a lesser extent, hydromorphones obtained the hydrocodone at a Childersburg
(Dilaudid) are significant and increasing threats pharmacy. A subsequent investigation by
to the Southeast region. NDTS 2004 data indicate Shelby County Drug Enforcement Task Force
a high percentage of state and local law enforce- officers and Alabama State Board of Pharmacy
ment agencies in the Southeast region report that investigators resulted in the arrest of the phar-
oxycodones (86.3%) and hydrocodones (81.1%) macy owners, who were husband and wife.
are commonly diverted and abused in their areas. Both were charged with conspiracy to commit a
A smaller percentage of agencies (17.6%) report controlled substance crime.
that hydromorphones are commonly diverted and Source: Harpsville Police Department.
abused in their areas.
Law enforcement survey data as well as
Regional drug prevalence data are not avail-
able; however, drug consequence data show DAWN and TEDS data indicate that prescription
depressant diversion and abuse are significant and
increases in the number of ED mentions and
treatment admissions for prescription narcotics. increasing threats to the Southeast region. NDTS
2004 data show that the percentages of state and
DAWN data indicate that the combined number
of ED mentions for “Narcotic Analgesics” (pre- local law enforcement agencies in the Southeast
scription narcotics) for the three DAWN reporting region that report Valium and Xanax are com-
monly diverted and abused in their areas are 79.7
cities in the Southeast region (Atlanta, Miami,
percent and 88.4 percent, respectively. DAWN
and New Orleans) increased significantly from
2000 (1,353 mentions), to 2001 (1,602 mentions), data show that the combined number of ED men-
tions for benzodiazepines (Valium and Xanax)
to 2002 (1,831 mentions). TEDS data show that
increased sharply in the three DAWN reporting
admissions to publicly funded treatment facilities
in the Southeast region for “Other Opiates” (pre- cities (Atlanta, Miami, and New Orleans) in the
Southeast region from 2000 (2,079 mentions), to
scription narcotics and opium) increased sharply
2001 (2,402 mentions), to 2002 (2,729 mentions),
from 2000 (7,724 admissions), to 2001 (10,351
the most recent year for which such data are
admissions), to 2002 (12,633 admissions), the
available. TEDS data show a sharp increase in the
most recent year for which data are available.
number of treatment admissions within the region
for prescription depressants (tranquilizers and region by stimulant diversion and abuse appears to
sedatives/hypnotics) such as Valium and Xanax. be lower than that of prescription narcotics and
According to TEDS, the number of treatment depressants. NDTS 2004 data show that only 53.0
admissions to publicly funded treatment facilities percent of state and local law enforcement agen-
in the Southeast region for depressants increased cies in the Southeast region report that Ritalin is
from 2000 (2,711 admissions), to 2001 (3,117 commonly diverted and illicitly used in their areas.
admissions), to 2002 (3,308 admissions). DAWN and TEDS data regarding the number of
The diversion and abuse of pharmaceutical ED mentions and treatment admissions to publicly
stimulants, particularly methylphenidate (Ritalin), funded treatment facilities for prescription stimu-
are a concern to law enforcement and public lants are not available.
health agencies; however, the threat posed to the
Midwest Region
NDTS data for 2004 show that 3.2 percent of of ED mentions for “Narcotic Analgesics” (pre-
state and local law enforcement agencies in the scription narcotics) for the four DAWN reporting
Midwest report that diverted pharmaceuticals cities in the Midwest region (Chicago, Detroit,
pose the greatest drug threat to their areas. More- Minneapolis, and St. Louis) increased sharply
over, NDTS 2004 data show that 2.6 percent of and steadily from 2000 (4,422 mentions), to 2001
agencies in the Midwest region report that (6,413 mentions), to 2002 (7,728 mentions). Fur-
diverted pharmaceuticals are the drugs contribut- thermore, TEDS data show that admissions to
ing most to violent crime in their areas, while 2.2 publicly funded treatment facilities in the Mid-
percent of agencies report that these drugs con- west region for “Other Opiates” (nonheroin opi-
tribute most to property crime. Although only a ates/synthetics) increased significantly from 2000
small percentage of state and local law enforce- (4,463 admissions), to 2001 (5,254 admissions),
ment agencies identify pharmaceuticals as the to 2002 (6,549 admissions), the most recent year
greatest drug threat in their areas, the diversion for which data are available.
and abuse of these drugs remain a concern. Law enforcement survey data as well as
The diversion and abuse of prescription nar- DAWN and TEDS data indicate that prescription
cotics such as oxycodones (OxyContin, Percocet, depressant diversion and abuse are a significant
and Percodan), hydrocodones (Lorcet and Vico- threat to the Midwest region. NDTS 2004 data
din) and, to a lesser extent, hydromorphones show that the percentages of state and local law
(Dilaudid) are significant and increasing threats enforcement agencies in the Midwest region that
to the Midwest region. NDTS 2004 data indicate report Valium and Xanax are commonly diverted
a high percentage of state and local law enforce- and abused in their areas are 71.2 percent and
ment agencies in the Midwest region report that 62.8 percent, respectively. DAWN data show that
oxycodones (60.9%) and hydrocodones (51.8%) the combined number of ED mentions for benzo-
are commonly diverted and abused in their areas. diazepines (Valium and Xanax) increased sharply
A smaller percentage of agencies (7.8%) report in the four DAWN reporting cities (Chicago,
that hydromorphones are commonly diverted and Detroit, Minneapolis, and St. Louis) in the Mid-
abused in their areas. west region from 2000 (5,995 mentions), to 2001
Regional drug prevalence data are not avail- (7,033 mentions), to 2002 (8,149 mentions), the
able; however, drug consequence data show most recent year for which such data are avail-
increases in the number of ED mentions and able. However, TEDS data have fluctuated in the
treatment admissions for prescription narcotics. number of treatment admissions within the region
DAWN data indicate that the combined number for prescription depressants (tranquilizers and
sedatives) such as Valium and Xanax. According to the region by stimulant diversion and abuse
to TEDS, the number of treatment admissions to appears to be lower than that of prescription nar-
publicly funded treatment facilities in the Mid- cotics and depressants. NDTS 2004 data show
west region for depressants decreased from 1,538 that 56.6 percent of state and local law enforce-
admissions in 2000 to 1,477 admissions in 2001, ment agencies in the Midwest region report that
but increased to 1,636 admissions in 2002. Ritalin is commonly diverted and illicitly used in
The diversion and abuse of pharmaceutical their areas. DAWN and TEDS data regarding the
stimulants, particularly methylphenidate number of ED mentions and treatment admis-
(Ritalin), are a concern to law enforcement and sions to publicly funded treatment facilities for
public health agencies; however, the threat posed prescription stimulants are not available.
Southwest Region
According to NDTS 2004 data, less than 1 enforcement agencies in the Southwest region
percent (0.3%) of state and local law enforcement report that hydrocodones (64.6%) and oxycodones
agencies in the Southwest report that diverted (42.1%) are commonly diverted and abused in
pharmaceuticals are the greatest drug threat to their areas. A smaller percentage of agencies
their areas. Similarly, just 0.3 percent of all (4.9%) report that hydromorphones are com-
responding agencies in the Southwest report that monly diverted and abused in their areas.
diverted pharmaceuticals contribute most to both Regional drug prevalence data are not avail-
property and violent crimes in their areas. able; however, drug consequence data show
The diversion and abuse of prescription nar- increases in the number of ED mentions and
cotics such as hydrocodones (Lorcet and Vico- treatment admissions for prescription narcotics.
din), oxycodones (OxyContin, Percocet, and DAWN data indicate that the combined number
Percodan) and, to a lesser extent, hydromor- of ED mentions for “Narcotic Analgesics” (pre-
phones (Dilaudid) are significant and increasing scription narcotics) for the two DAWN reporting
threats to the Southwest region. NDTS 2004 data cities in the Southwest region (Dallas and Phoe-
indicate a high percentage of state and local law nix) increased from 2000 (1,282 mentions), to
Pacific Region
Less than 1 percent (0.2%) of state and local Regional drug prevalence data are not avail-
law enforcement agencies in the Pacific region able; however, drug consequence data show high
report that diverted pharmaceuticals are the great- numbers for ED mentions and increases in treat-
est drug threat to their areas, according to NDTS ment admissions for prescription narcotics.
2004 data. Moreover, a very low percentage of DAWN data indicate that the combined number
agencies in the Pacific region report that diverted of ED mentions for “Narcotic Analgesics” (pre-
pharmaceuticals contribute most to violent crime scription narcotics) for the four DAWN reporting
(0.2%) and property crime (0.7%). cities in the Pacific region (Los Angeles, San
The diversion and abuse of prescription nar- Diego, San Francisco, and Seattle) fluctuated but
cotics such as hydrocodones (Lorcet and Vico- remained high from 2000 (3,785 mentions), to
din), oxycodones (OxyContin, Percocet, and 2001 (5,287 mentions), to 2002 (4,778 mentions).
Percodan) and, to a lesser extent, hydromor- TEDS data show that admissions to publicly
phones (Dilaudid) are significant and increasing funded treatment facilities in the Pacific region
threats to the Pacific region. NDTS 2004 data for “Other Opiates” (nonheroin opiates/synthet-
indicate a high percentage of state and local law ics) increased from 2000 (3,409 admissions), to
enforcement agencies in the Pacific region report 2001 (3,680 admissions), to 2002 (4,676 admis-
that hydrocodones (59.7%) and oxycodones sions), the most recent year for which data are
(59.5%) are commonly diverted and abused in available.
their areas. A smaller percentage of agencies Law enforcement survey data as well as TEDS
(7.4%) report that hydromorphones are com- and DAWN data indicate that prescription depres-
monly diverted and abused in their areas. sant diversion and abuse are significant and
increasing threats to the Pacific region. NDTS
Members of Polydrug Trafficking 2004 data show that the percentage of state and
Organization Arrested local law enforcement agencies in the Pacific
On September 9, 2004, the California Depart- region that report Valium and Xanax are com-
ment of Justice released information regarding monly diverted and abused in their areas are 73.7
the arrests of 26 members of a Sacramento- percent and 44.7 percent, respectively. DAWN
based polydrug trafficking organization alleg- data show that the combined number of ED men-
edly involved in the trafficking of diverted phar-
tions for benzodiazepines (Valium and Xanax)
maceuticals as well as steroids, marijuana, and
methamphetamine. Since April 2004 law
increased slightly in the four DAWN reporting cit-
enforcement authorities have seized 250 Vico- ies (Los Angeles, San Diego, San Francisco, and
din tablets, 250 oxycodone tablets, an unspeci- Seattle) in the Pacific region from 2000 (5,194
fied quantity of steroids, more than 100 pounds mentions), to 2001 (5,314 mentions), to 2002
of marijuana, and 1 pound of methamphet- (5,316 mentions), the most recent year for which
amine. Assets seized as a result of the investi- such data are available. TEDS data show an
gation have included 34 weapons, 13 increase in the number of treatment admissions
motorcycles, 9 vehicles, 2 boats, a motor within the region for prescription depressants
home, and over $127,000. Numerous sheriff’s (tranquilizers and sedatives) such as Valium and
offices, area task forces, and police depart- Xanax. According to TEDS, the number of treat-
ments, the Sacramento County District Attor- ment admissions to publicly funded treatment
ney’s Office, California Highway Patrol, and facilities in the Pacific region for depressants
California Department of Corrections have
increased from 2000 (902 admissions), to 2001
assisted in the investigation.
(1,081 admissions), to 2002 (1,128 admissions).
Source: California Department of Justice.
The diversion and abuse of pharmaceutical percent of state and local law enforcement agen-
stimulants, particularly methylphenidate (Ritalin), cies in the Pacific region report that Ritalin is com-
are a concern to law enforcement and public monly diverted and illicitly used in their areas.
health agencies; however, the threat posed to the DAWN and TEDS data regarding the number of
region by stimulant diversion and abuse appears to ED mentions and treatment admissions to publicly
be lower than that of prescription narcotics and funded treatment facilities for prescription stimu-
depressants. NDTS 2004 data show that only 40.8 lants are not available.
West Region
According to NDTS 2004 data, 0.0 percent of Furthermore, TEDS data show that admissions to
the state and local law enforcement agencies in the publicly funded treatment facilities in the West
West region report that pharmaceuticals are the region for “Other Opiates” (nonheroin opiates/
greatest drug threat to their areas. Additionally, 0.0 synthetics) increased from 2000 (1,116 admis-
percent of the agencies reported that diverted sions), to 2001 (1,219 admissions), to 2002
pharmaceuticals contribute most to violent crime (1,380 admissions), the most recent year for
in their areas; however, a few agencies (0.2%) which data are available.
report that diverted pharmaceuticals are the drugs
that contribute most to property crime in their Traffic Stop Results in
areas. Although in comparison with illicit drugs, Large Codeine Seizure
the threat posed to the West by diverted pharma- On May 26, 2004, a Utah Highway Patrol trooper
ceuticals is relatively small, law enforcement arrested a 26-year-old male and a 27-year-old
agencies in the West region report ready availabil- male and seized 13 gallons of promethazine
ity and frequent abuse of prescription drugs. cough syrup with codeine during a routine traffic
stop on Interstate 70. The trooper initially
The diversion and abuse of prescription nar- stopped the vehicle for speeding. During routine
cotics such as oxycodones (OxyContin, Percocet, questioning, the driver advised the trooper that
and Percodan), hydrocodones (Lorcet and Vico- he and his passenger were returning to Ken-
din) and, to a lesser extent, hydromorphones tucky after a visit to Las Vegas. The trooper
(Dilaudid) are significant and increasing threats obtained permission to run a check on the
to the West region. NDTS 2004 data indicate a driver’s Kentucky license. The trooper discov-
high percentage of state and local law enforce- ered that the driver’s license had been sus-
ment agencies in the West region report that oxy- pended and took the driver into custody. The
trooper then called for backup and requested
codones (78.1%) and hydrocodones (71.1%) are
and received consent to search the vehicle. The
commonly diverted and abused in their areas. A troopers discovered a snow cone-making
smaller percentage of agencies (11.3%) report machine and 13 snow cone syrup containers in
that hydromorphones are commonly diverted and the trunk. The troopers became suspicious after
abused in their areas. noticing that 10 of the syrup containers had
Regional drug prevalence data are not avail- been opened and resealed. The passenger indi-
able; however, drug consequence data show a sig- cated that he had purchased the snow cone
nificant number of ED mentions and treatment maker and syrup in California. The driver and
passenger were detained while a sample of the
admissions for prescription narcotics. DAWN
liquid was taken to a laboratory for immediate
data indicate that the combined number of ED testing. When test results identified the sub-
mentions for “Narcotic Analgesics” (prescription stance as codeine, both were arrested and
narcotics) for the one DAWN reporting city in the charged with possession of a controlled
West region (Denver) fluctuated but remained substance.
significant from 2000 (396 mentions), to 2001
Source: Utah Highway Patrol.
(531 mentions), to 2002 (395 mentions).
Law enforcement survey data as well as admissions to publicly funded treatment facilities
DAWN and TEDS data indicate that diversion in the West region for depressants increased from
and abuse of prescription depressants are signifi- 2000 (365 admissions), to 2001 (373 admissions),
cant threats to the West region. NDTS 2004 data to 2002 (640 admissions).
show that the percentages of state and local law The diversion and abuse of pharmaceutical
enforcement agencies in the West region that stimulants, particularly methylphenidate (Ritalin),
report Valium and Xanax are commonly diverted are a concern to law enforcement and public
and abused in their areas are 65.5 percent and health agencies; however, the threat posed to the
62.9 percent, respectively. DAWN data show that region by stimulant diversion and abuse appears to
the combined number of ED mentions for benzo- be lower than that of prescription narcotics and
diazepines (Valium and Xanax) fluctuated but depressants. NDTS 2004 data show that only 52.3
remained significant in the one DAWN reporting percent of state and local law enforcement agen-
city (Denver) in the West region from 2000 (568 cies in the West region report that Ritalin is com-
mentions), to 2001 (644 mentions), to 2002 (504 monly diverted and illicitly used in their areas.
mentions), the most recent year for which such DAWN and TEDS data regarding the number of
data are available. TEDS data indicate increases ED mentions and treatment admissions to publicly
in the number of treatment admissions within the funded treatment facilities for prescription stimu-
region for prescription depressants (tranquilizers lants are not available.
and sedatives) such as Valium and Xanax.
According to TEDS, the number of treatment
Outlook
The abuse of pharmaceutical drugs is likely to Despite a possible rise in the diversion of phar-
decline in the near term. MTF data indicate that maceutical drugs via the Internet, pharmaceutical
rates of past year use for pharmaceutical narcotics, drug diversion is likely to decrease overall in the
depressants, and stimulants have increased sharply near term. Sharp increases in law enforcement
from the early to mid-1990s to 2001-2002 but pressure on unscrupulous physicians as well as
have since declined for nearly every surveyed age increasing use of statewide prescription monitor-
group. In fact, only rates of past year use for pre- ing programs could sharply reduce the illegal
scription narcotics among young adults (aged 19 diversion of prescription drugs through illegal pre-
to 28) have increased from 2001 (5.0%) to 2003 scribing, prescription fraud, and doctor shopping.
(8.5%). Rates of past year use for prescription Moreover, increasing protection of pharmaceutical
stimulants and depressants have declined or drug inventories at individual pharmacies will
remained stable for every surveyed age group likely further reduce the amount of pharmaceuti-
from 2002 to 2003. cals illegally diverted through theft.
Sources
State
Florida
Kentucky
Cabinet for Health Services
Department for Public Health
Drug Enforcement and Professional Practices Branch
Kentucky All Schedule Prescription Electronic Reporting System
Maryland
Maryland State Police
Office of the Maryland Attorney General
Massachusetts
Department of Corrections
Middlesex County House of Correction
Middlesex County Superior Court
Office of the Massachusetts Attorney General
Federal
Executive Office of the President
Office of National Drug Control Policy
U.S. Department of Health and Human Services
National Institutes of Health
National Institute on Drug Abuse
Monitoring the Future
Substance Abuse and Mental Health Services Administration
Office of Applied Studies
Drug Abuse Warning Network
National Survey on Drug Use and Health
Treatment Episode Data Set
U.S. Food and Drug Administration
Other
American Society of Interventional Pain Physicians
Columbia University
National Center on Addiction and Substance Abuse
National Association of Boards of Pharmacy
University of Florida
Pharmaceuticals
Drug Threat Assessment
Product No. 2004-L0487-001 November 2004