MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
ABO ABO isoimmunization
ACBT ACBT
ACE ACE inhibitor foetopathy
ACTH ACTH stimulation test normal
ADA ADA deficiency

ADAMTS13 ADAMTS13 activity abnormal

ADD ADD
ADH ADH normal
ADMA ADMA abnormal
AFP AFP result - normal
AG AG ratio abnormal
AIDS AIDS retinopatHy
Alk phos Alk phos raised
ALK ALK receptor tyrosine kinase assay
ALK-NPM ALK-NPM gene fusion assay
ALP ALP increased
ALT ALT increased
ANA ANA present
ANCA ANCA positive
ANNA ANNA-1; ANNA-2
ANP ANP
APACHE II APACHE II score increased

APGAR Apgar score normal

aPTT APTT prolonged

ARC ARC

ARIA ARIA; ARIA-E; ARIA-H

ASCA ASCA
ASO ASO titre

03/06/2014 Page 1 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
AST AST increased
ATRA ATRA syndrome
AZOOR AZOOR
BCL-2 BCL-2 gene status assay
BCC BCC excision
BCG BCG related lymphadenitis
BAFF BAFF polymorphism
BGP BGP
BNP BNP normal
BP BP raised
BPSD BPSD
Br Br
BRCA BRCA1 gene mutation
BSP BSP excretion delayed
BUN BUN normal
C1 C1 inhibitor functional assay
CA Ca phobia
CCR CCR5 receptor positive

CANDLE CANDLE syndrome

CPFE CPFE
CAT CAT
CBC CBC normal
CEA CEA antigen increased

CHARGE CHARGE syndrome

CI CI increased
Chronic inflammatory demyelinating
CIDP
polyradiculoneuropathy
CIS CIS of cervix

03/06/2014 Page 2 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
CK CK normal
Cl Cl
CLIPPERS CLIPPERS syndrome

CLL CLL variants

CML CML progression
CMV CMV viremia
CNS CNS ventriculitis, CNS toxicity
CO2 CO2 total abnormal NOS
COPD COPD exacerbation
CPAP Nasal CPAP
CPK CPK normal
CREST CREST syndrome
CRMO CRMO
CRP CRP positive
CRT/ICD CRT/ICD insertion
CSF CSF white cell count NOS normal
CT CT urography
Cu Cu
CVP CVP normal
CXR CXR normal
CYP CYP2C19 intermediate metaboliser status
DEXA DEXA scan
DILI Drug-induced liver injury
DNA DNA test for fragile X
DPD DPD deficiency
DRESS DRESS syndrome
DVT DVT prophylaxis
EBV EBV viremia
ECG ECG signs of ventricular hypertrophy
ECHO Echo virus infection NOS

03/06/2014 Page 3 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
ECT ECT (electro-convulsive therapy)
EEG EEG provocation test positive
EGFR EGFR gene mutation
EKG EKG normal
EMG EMG normal
EMG EMG

EMPACT EMPACT syndrome

ENT ENT examination normal

EPCR A3 EPCR A3 polymorphism
ESR ESR retarded
ESR ESR1 positive
FCAS FCAS
Fe Fe
FEV FEV1/FVC ratio
FGF FGF-23
FISH FISH test
FNAITP FNAITP
FOB FRC
FOB negative
FRC abnormal
FRC
FRC decreased
FSH FSH normal
FRC increased
FTA FTA present
FVC FEV1/FVC ratio
G-CSF G-CSF therapy
GFR GFR raised
GGT GGT increased
GGTP GGTP increase
GSPECT GSPECT
GH GH normal
GI GI upset
GIFT GIFT

03/06/2014 Page 4 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
GM-CSF GM-CSF therapy
GOT GOT normal
G6PD G6PD deficiency
GPT GPT normal
GTT GTT
GVH GVH disease
H-ras H-ras gene mutation
Hb Hb decreased
HbA1c HbA1C increased
HBV HBV viral load increased
HCV HCV viral load increased
HDL HDL raised

HELLP HELLP syndrome

HER HER2 gene amplification

HERG HERG gene mutation
HGPRT HGPRT deficiency
Hib HIB meningitis

HIV HIV with persistent generalized adenopathy

HLA HLA marker tests NOS

hMPV hMPV test

HOCM HOCM Hypertrophic obstructive cardiomyopathy

HRT HRT
HSIL Anal HSIL
HSV HSV infection
HTLV HTLV test positive
IA Anti-IA2 antibody negative
IBD IBD
ICD CRT/ICD insertion

03/06/2014 Page 5 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
Ig Ig E increased
IgA IgA nephropathy
IgD IgD myeloma
IgE IgE normal
IgG IgG subclass deficiency
IgM IgM increased
INR INR increased
IOP IOP increased
IQ IQ test normal
IRIS IRIS associated Kaposi's sarcoma
IRVAN IRVAN syndrome
IUCD IUCD expelled
IVP IVP normal
IVU IVU normal
JAK-2 JAK-2 mutation
JVP JVP normal
K K
K-ras K-ras status assay
KCCT KCCT increased
KUB KUB X-ray
Lab Lab test interference
LADA Latent autoimmune diabetes in adults
LCAD LCAD deficiency
LCAT Familial LCAT deficiency
LCHAD LCHAD deficiency
LCM LCM virus infection
LDH LDH increased urine
LDL LDL raised
LDLR LDLR mutation
LE LE type reaction
LH LH normal

03/06/2014 Page 6 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
LP LP
LSIL Anal LSIL
LV LV dyssynchrony
LVF LVF
MAP MAP increased
MCH MCH normal
MCV MCV abnormal
MDS MDS transformation
MELD MELD score
MEN MEN Type II
MERS MERS
Mg Mg reduced
MRI MRI normal
MRSA MRSA wound infection
MS MS hug
MTHFR MTHFR gene mutation
N-ras N-ras status assay
Na Na increased
NAIT NAIT
NAT NAT2 polymorphism
NK NK cell count increased
NMDA Anti-NMDA antibody
NT-proBNP NT-proBNP increased
NMR NMR normal
O2 O2 saturation
OA OA toes
OC OC
ORSA ORSA infection
P P

PANDAS PANDAS

03/06/2014 Page 7 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
PANSS PANSS score
Pap Pap smear abnormal
Pb Pb
PCV PCV normal
PCV PCV
PDGF PDGF receptor assay
PEFR PEFR normal
PET PET scan normal
PgR PgR positive
PID PID Pelvic inflammatory disease
PIH PIH Pregnancy induced hypertension
PNET PNET of bone localized

POEMS POEMS syndrome

POLG POLG mutation

PPD PPD skin test
PR PR shortened
PSA PSA normal
PSP PSP test normal
PT PT prolonged
PTH PTH normal
PTT PTT prolonged
Bleeding PU
PU
Healed PU
PUD PUD
QSART QSART
RA RA latex test
RBC RBC urine
RDW RDW increased
REM REM sleep abnormal
RET RET gene mutation

03/06/2014 Page 8 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
RH Rh isoimmunization
RPR RPR syphilis test positive
RSV RSV serology positive
RTI RTI
RUQ RUQ pain
RVF RVF
RVH RVH
SA SA block
SARS SARS virus test positive
SCAD SCAD deficiency
Se Se
SeHCAT SeHCAT test
SGOT SGOT normal
SGPT SGPT normal

SIDS SIDS (Sudden infant death syndrome)

SLE SLE syndrome aggravated

SMART SMART syndrome

SPECT SPECT normal

STA-MCA STA-MCA bypass operation

TRAcP TRAcP 5b low

TAPSE TAPSE
TAR TAR syndrome
TB TB spine
TCT TCT
TdP TdP ventricular tachycardia

03/06/2014 Page 9 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
TEMPI TEMPI syndrome

TIBC TIBC normal

TLC abnormal
TLC
TLC decreased
TLC normal
TMJ TMJ syndrome
TOP TOP on mental grounds
TPMT TPMT poor metaboliser status
TAVI TAVI
TRAM Tram flap breast reconstruction
TRAP TRAP sequence malformation
TSH TSH increased
TUEVAP TUEVAP
TURBT TURBT
TUVP TUVP
UC UC aggravated
UGI UGI bleed
UGT UGT1A1 gene mutation
URTI URTI (upper respiratory tract infection)
V/Q V/Q scan
VC VC
VD VD
VDRL VDRL positive
VEGF VEGF assay
VGCC Anti-VGCC antibody
VIP VIP test
VGKC Anti-VGKC antibody
VLCAD VLCAD deficiency
VLDL VLDL raised

03/06/2014 Page 10 of 22
 MedDRA LLT Abbreviations / Acronyms

Abbreviation /
MedDRA LLT (current LLTs only)
Acronym
WBC WBC scan
WPW WPW syndrome
wt Wt loss
YMRS YMRS
Zn Zn normal
ZnT8 Anti-ZnT8 antibody

03/06/2014 Page 11 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Landsteiner's blood grouping system
Active cycle of breathing technique
Angiotensin-converting enzyme
Adrenocorticotropic hormone
Adenosine deaminase
A distintegrin and metalloprotease with thrombospondin type 13 motif (von Willebrand factor
cleavage protease)
Attention deficit disorder
Antidiuretic hormone
Asymmetric di-methylarginine
Alpha-fetoprotein
Albumin - Globulin
Acquired immune deficiency syndrome
Alkaline phosphatase(sometimes abbreviated as ALP)
Anaplastic lymphoma receptor tyrosine kinase
Anaplastic lymphoma kinase and nucleophosmin
Alkaline phosphatase(sometimes abbreviated as Alk phos)
Alanine transaminase
Antinuclear antibody
Antineutrophil cytoplasmic antibody
Anti-neuronal nuclear antibody
Atrial natriuretic peptide
Acute Physiology and Chronic Health Evaluation II

Appearance, pulse, grimace, activity, respiration- used to assess newborns

Activated partial thromboplastin time

AIDS related complex
Amyloid related imaging abnormality (where appended E stands for edema and H
stands for microhaemorrhage and haemosiderin deposits)
Anti-saccharomyces cerevisiae antibody
Antistreptolysin-O

03/06/2014 Page 12 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Aspartate transaminase
All-trans retinoic acid
Acute zonal occult outer retinopathy
B-cell lymphoma 2
Basal cell carcinoma
Bacille Calmette-Guerin(atuberculosisvaccination)
B- cell activating factor
Osteocalcin (bone Gla-protein bone marker)
Brain natriuretic peptide
Blood pressure
Behavioural and psychiatric symptoms of dementia
Bromide
Breast cancer gene 1
Bromsulphthalein
Blood urea nitrogen
Complement factor C1
Carcinoma
Chemokine receptor
Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature
syndrome
Combined pulmonary fibrosis and emphysema
Computed axial tomography
Complete blood count
Carcinoembryonic antigen
Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth
and/or development, Genital and/or urinary abnormalities, and Ear abnormalities and
deafness.
Cardiac index

Chronic inflammatory demyelinating polyradiculoneuropathy

Carcinoma in situ

03/06/2014 Page 13 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Creatine kinase
Chloride
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids

Chronic lymphocytic leukemia

Chronic myelogenous leukemia, also called chronic myeloid leukaemia
Cytomegalovirus
Central nervous system
Carbon dioxide
Chronic obstructive pulmonary disease
Continuous positive airway pressure
Creatine phosphokinase
Calcinosis, Raynaud esophagus, sclerosis, teleangiectasia
Chronic recurrent multifocal osteomyelitis
C-reactive protein
Cardiac resynchronization therapy / implantable cardioverter defibrillator
Cerebrospinal fluid
Computed tomography
Copper
Central venous pressure
Chest x-ray
Cytochrome P450
Dual energy X-ray absorptiometry
Drug induced liver injury
Deoxyribonucleic acid
Dihydropyrimidine dehydrogenase
Drug reaction with eosinophilia and systemic symptoms
Deep vein thrombosis
Epstein-Barr virus
Electrocardiogram
Enteric cytopathic human orphan virus

03/06/2014 Page 14 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Electroconvulsive therapy
Electroencephalogram
Epidermal growth factor receptor
Electrocardiogram
Electromyography
Electromyogram
Erythema multiforme associated with phenytoin and cranial radiation therapy
syndrome
Ear, nose, and throat (seeotolaryngology)
Endothelial protein C receptor
Erythrocyte sedimentation rate
Estrogen/Oestrogen receptor
Familial cold autoinflammatory syndrome
Iron
Forced expiratory volume
Fibroblast growth factor
Fluorescence in situ hybridization
Fetal and neonatal alloimmune thrombocytopenia
Fecal occult blood
Functional residual capacity
Follicle-stimulating hormone
Fluorescent treponemal antibody (seesyphilis)
Forced vital capacity
Granulocyte colony-stimulating factor
Glomerular filtration rate
Gamma glutamyl transferase
Gamma glutamyl transpeptidase
Gated single photon emission computerised tomogram
Growth hormone
Gastrointestinal;
Gamete intrafallopian transfer

03/06/2014 Page 15 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Granulocyte macrophage colony-stimulating factor
Glutamic-oxalacetic transaminase
Glucose-6-phosphate dehydrogenase
Glutamic-pyruvic transaminase
Glucose tolerance test
Graft-versus-Host
Harvey rat sarcoma oncogene
Hemoglobin
Glycosylated Hemoglobin(used as a measure ofdiabetescontrol)
Hepatitis B virus
Hepatitis C virus
High-density lipoprotein

Haemolysis,elevated liver enzymes, lowplatelets(syndrome) (inpregnancy)

Human epidermal growth factor receptor

Human ether--go-go related gene
Hypoxanthine-guanine phosphoribosyl transferase
Haemophilus influenzae B

Human immunodeficiency virus

Human leukocyte antigen

Human metapneumovirus

Hypertrophic obstructive cardiomyopathy

Hormone replacement therapy

High grade squamous intraepithelial lesion
Herpes simplex virus
Human T-lymphotropic virus
Islet antigen
Inflammatory bowel disease
Implantable cardioverter defibrillator

03/06/2014 Page 16 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Immunoglobulin
Immunoglobulin A
Immunoglobulin D
Immunoglobulin E
Immunoglobulin G
Immunoglobulin M
International normalized ratIo
Intraocular pressure
Intelligence quotIent
Immune reconstitution inflammatory syndrome
Idiopathic retinal vasculitis, aneurysms and neuroretinitis syndrome
Intrauterine contraceptive device
Intravenous pyelogram
Intravenous urogram
Janus kinase 2
Jugular venous pressure
Potassium
Kirsten rat sarcoma oncogene
Kaolin cephalin clotting time (seePartial thromboplastin time)
Kidneys, ureters, and bladder(x-ray)
Laboratory
Latent autoimmune diabetes in adults
Long-chain acyl-coenzyme A dehydrogenase
Lecithin-cholesterol acyltransferase
Long-chain acyl-coenzyme A dehydrogenase
Lymphocytic meningitis
Lactate dehydrogenase
Low-density lipoprotein
Low-density lipoprotein receptor
Lupus erythematosus(in Germanlupus erythematodes)
Luteinizing hormone

03/06/2014 Page 17 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Lumbar puncture
Low grade squamous intraepithelial lesion
Left ventricle
Left ventricular failure
Mean arterial pressure
Mean cell hemoglobin;
Mean corpuscular volume
Myelodysplastic syndrome
Model for end stage liver disease score
Multiple endocrine neoplasia
Middle East respiratory syndrome
Magnesium
Magnetic resonance imaging
Methicillin-resistantStaphylococcus aureus
Multiple sclerosis(fromLatinsclerosis multiplex)
Methylenetetrahydrofolate reductase
Neuroblastoma rat sarcoma oncogene
Sodium(from Latinnatrium)
Neonatal alloimmune thrombocytopenia
N-acetyltransferase
Natural killer cells
Anti-N-methyl-D-aspartate receptor antibody
N-terminal prohormone brain natriuretic peptide
Nuclear magnetic resonance
Oxygen
Osteoarthritis
Oral contraception
Oxacillin-resistant staphylococcus aureus
Phosphorus
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal
infection

03/06/2014 Page 18 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Positive and negative syndrome scale
Papanicolaou test(pap smear)
Lead
Packed cell volume (seeHematocrit)
Packed cell volume
Platelet-derived growth factor receptor
Peak expiratory flow rate
Positron-emission tomography(cerebral metabolic scan)
Progesterone receptor
Pelvic inflammatory disease
Pregnancy induced hypertension
Primitive neuroectodermal tumour

Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes

Polymerase gamma
Purified protein derivative
Prothrombin ratio
Prostate-specific antigen
Phenolsulfonphthalein
Prothrombin time
Parathyroid hormone
Partial thromboplastin time
Bleeding peptic ulcer
Peptic ulcer healed
Peptic ulcer disease
Quantitative sudomotor axon reflex test
Rheumatoid arthritis
Red blood cells, red blood count
Red celldistribution width
Rapid eye movement
Rearranged during transfection

03/06/2014 Page 19 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Rhesus factor
Rapid plasma reagintest
Respiratory syncytial virus
Respiratory tract infection
Right upper quadrant(see alsoregions of the abdomen)
Right ventricular failure
Right ventricular hypertrophy
Sinoatrial node
Severe acute respiratory syndrome
Short-chain acyl-coenzyme A dehydrogenase
Selenium
Selenium homocholic tauroselcholic acid test
Serum glutamic oxaloacetic transaminase
Serum glutamic pyruvic transaminase

Sudden infant death syndrome

Systemic lupus erythematosus

Stroke-like migraine attacks after radiation therapy

Single photon emission computed tomography

Superficial temporal artery to middle cerebral artery

Tartrate-resistant acid phosphatase decreased

Tricuspid annular plane systolic excursion
Thrombocytopenia-absent radius
Tuberculosis
Thrombin clotting time
Torsades de pointes

03/06/2014 Page 20 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
Telangiectasias, elevated erythropoietin and erythrocytosis, monoclonal gammopathy,
perinephric fluid collection, and intrapulmonary shunting
Total iron binding capacity

Total lung capacity

Temporomandibular joint
Termination of pregnancy
Thiopurine methyltransferase
Transcatheter aortic valve implantation
Transverse rectus abdominis myocutaneous flap (TRAM flap)
Twin reversed arterial perfusion
Thyroid stimulating hormone
Transurethral electrovaporization of prostate
Transurethral resection of bladder tumor
Transurethral vaporization of prostate
Ulcerative colitis
Upper gastrointestinal
Uridine diphosphoglucuronosyl transferase (UGT1A1) gene
Upper respiratory tract infection
Ventilation/perfusion scan
Vital Capacity
Sexually Transmitted Disease
Venereal Diseases Research Laboratory(old test forsyphilis)
Vascular endothelial growth factor
Voltage-gated calcium channel
Vasoactive intestinal peptide
Voltage-gated potassium channel
Very long-chain acyl-coenzyme A dehydrogenase
Very low density lipoprotein

03/06/2014 Page 21 of 22
 MedDRA LLT Abbreviations / Acronyms

Meaning
White blood cell
Wolff-Parkinson-White syndrome
Weight(whetherhuman weightor otherwise)
Young mania rating scale
Zinc
Zinc transporter 8

03/06/2014 Page 22 of 22