Session III


The Role of Beta and Islet Cell

Physiology in Practice Decisions
in type 2 Diabetes


Translation to Clinical Practice

In an average month:
1000 people

800 have symptoms

327 consider seeking

medical care

217 visit a physician’s

office
113 visit primary care
physician’s office

65 visit CAM provider

21 visit a hospital
outpatient clinic

14 receive home
health care

13 visit an emergency
department

8 are in a hospital

New Ecology of Medical Care - 2000 <1 is in an academic

health center hospital
 Office Visits by Physician Specialty

Total 880,487 visits Total Primary Care = 51.8%, 456,092

Source: National Center for Health Statistics, CDC, 2001

 Office Visits by Physician Specialty

Total 880,487 visits Total Primary Care = 51.8%, 456,092

Source: National Center for Health Statistics, CDC, 2001

 Office Visits by Physician Specialty

Total 880,487 visits Total Primary Care = 51.8%, 456,092

Source: National Center for Health Statistics, CDC, 2001

 Office Visits by Physician Specialty

Total 880,487 visits Total Primary Care = 51.8%, 456,092

Source: National Center for Health Statistics, CDC, 2001

 Office Visits by Physician Specialty

Total 880,487 visits Total Primary Care = 51.8%, 456,092

Source: National Center for Health Statistics, CDC, 2001

 The NIH Roadmap for 

Medical Research
www.nihroadmap.nih.gov

Address evolving health care challenges

 Research Teams of the Future

New Pathways to Discovery

 Research Teams of the Future

New Pathways to Discovery

 Research Teams of the Future

New Pathways to Discovery

 Research Teams of the Future

New Pathways to Discovery

 Research Teams of the Future

New Pathways to Discovery

 Translational Research
Research
T1Teams of the Future
T2
Research Research
Case Series Human Clinical Research
Phase 1 and 2 Clinical Trials Controlled Observational Studies
Phase 3 Clinical Trials

Translation to the
Basic Science Community
Preclinical Research
Animal Research

T2
Effectiveness T3
(Practical) Trials
Guideline Development
Practice-basedDissemination
Research Research
Meta-analysis
ObservationalImplementation
Studies Research
Systematic Phase
Reviews
3 Clinical Trials
Translation to patients Translation to practice

New Pathways to Discovery

Inventory and Evaluation of
Clinical Research Networks
(IECRN)
Goals
•  Inventory and database of CRNs
•  Barriers and facilitators of success
•  Best practices
•  Recognize network achievements
IECRN findings

•  Final report issued July 28, 2006

–  https://www.clinicalresearchnetworks.org
•  261 eligible networks
•  Average age 9.6 years (median 6)
•  60% received majority of funding from
federal government
•  Clinical trials (58%) observational epi
(13%), other observational (11%)
•  92% affiliated with an academic institution