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PARMETROS
BIODISPONIBILIDAD
VOLUMEN DE DISTRIBUCIN
ELIMINACIN
SEMIVIDA DE ELIMINACIN
ESTADO DE EQUILIBRIO
CAPTOPRIL
ENALAPRIL TOS SECA
LISINOPRIL INSUFICIENCIA RENAL
BENAZEPRIL HIPERKALEMIA
QUINAPRIL TERATOGENO
RAMIPRIL
Pharmacology
Indication For the symptomatic treatment of adult
patients with nocturnal heartburn due to
gastroesophageal reflux disease.
Pharmacodynamics Cisapride is a
parasympathomimetic which acts as a serotonin 5-
HT4 agonist. Stimulation of the serotonin receptors
increases acetylcholine release in the enteric nervous
system. Cisapride stimulates motility of the upper
gastrointestinal tract without stimulating gastric, biliary,
or pancreatic secretions. Cisapride increases the tone
and amplitude of gastric (especially antral)
contractions, relaxes the pyloric sphincter and the
duodenal bulb, and increases peristalsis of the
duodenum and jejunum resulting in accelerated
gastric emptying and intestinal transit. It increases the
resting tone of the lower esophageal sphincter.
Acta principalmente en
receptores opioides perifricos, no
acta en SNC
Puede utilizarse desde los 2 aos
de edad
En adultos se puede ingerir hasta
16mg/ da
Tiene una vida media de 11 horas,
alcanza su pico de 3 a 5 horas
Coadyuvante en el tratamiento de
la diarrea crnica.
REACCIONES ADVERSAS