108 PatentsALERT- Selected Patents Relevant to Fluorine Chemistry 99-I 18

5505932 blown foams. The foams of the present invention are

suitable for use in shoe sole applications.
METHOD FOR THE PREPARATION OF
FLUOROCARBON-CONTAINING 5506281
POLYMERIC SHELLS FOR MEDICAL
IMAGING COPOLYMER OF THE
TETRAFLUOROETHYLENE-ETHYLENE
Grinstaff Mark; Desai Neil; Suslick Kenneth S; TYPE HAVING A CORE-SHELL
Soon-Shiong Patric; Sandford Paul A; Merideth Noma PARTICLE STRUCTURE
Pasadena, CA, UNITED STATES assigned to Vivorx
Pharmaceuticals Inc Muhlbauer Hans P Feldafing, GERMANY assigned
to Hoechst Aktiengesellschaft
In accordance with the present invention, compositions
comprising imaging agent(s) contained within Aqueous dispersions of colloidal particles comprising
polymeric shells are provided. Invention compositions a particle core and at least one particle shell are
are useful, for example, as contrast agents for magnetic obtained by preparing a seed dispersion by
resonance imaging (MRI), ultrasonography, and X-ray copolymerization of tetrafluoroethylene, ethylene and,
computer tomography. The polymeric shell diameter is if desired, further fluoroolefinic comonomers and then
typically approximately 2 microns in diameter. continuing the polymerization by supplying the
Consequently, these materials have organ specificity monomers for the particle shell, where the particle shell
due to rapid scavenging by the reticuloendothial system is a polymer having a melting pointat least 20 degrees
(RES) or the mononuclear phagocyte (MNP) system C. lower than that of the particle core, and where the
upon intravenous injection. Furthermore, polymeric volume of the particle shell is from 1 to 26% by
shells of the invention can be used to measure and volume of the total volume. These dispersions can be
monitor local oxygen and temperature. Exemplary coagulated or spray dried to give powders which are
contrast agents contemplated for use in the practice of suitable for the production of porous structures.
the present invention include fluorinated compounds.
Fluorinated compounds in general are hydrophobic and
as such have limited water solubility. The invention 5506364
method permits preparation of such compounds in a
biocompatible form suitable for ready delivery. PROCESS FOR THE PRODUCTION OF
BIS(FLUOROMETHYL)ETHER AND
DIFLUOROMETHANE
5506275
Martin John; Ryan Thomas; Spooncer Rachel
1,1,1,2-TETRAFLUOROETHANE AS A Northwich, UNITED KINGDOM assigned to Imperial
BLOWING AGENT IN INTEGRAL SKIN Chemical Industries PLC
POLYURETHANE SHOE SOLES
A process for the production of bis(fluoromethyl)ether
Valoppi Valeri L Riverview, MI, UNITED STATES by contacting formaldehyde with hydrogen fluoride in
assigned to BASF Corporation a reaction/distillation vessel. The reaction/distillation
vessel is preferably a reaction/distillation column
It has been found that 1,I ,I ,2-tetrafluoroethane through which formaldehyde and hydrogen fluoride
(I-WC-134a) may be used alone or in combination with preferably flow in counter current. The
water as blowing agents in flexible integral skin foams. bis(fluoromethyI)ether may be converted to
Foams prepared using HFC-I 34a alone or in difluoromethane, preferably by heating the
combination with water exhibit physical characteristics bis(fluoromethyl)ether to elevated temperature in the
such as resistance to abrasion and cracking on flex presence of a metal, metal oxide, metal fluoride or
comparable to conventional chlorinated fluorocarbon metal oxyfluoride catalyst.