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Journal of Anxiety Disorders xxx (2016) xxxxxx
Mental Health Service, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC, United States
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, United States
a r t i c l e
i n f o
Article history:
Received 23 October 2015
Received in revised form 3 March 2016
Accepted 21 April 2016
Available online xxx
Keywords:
Transdiagnostic Behavior Therapy
TBT
Dissemination
Implementation
Veterans
Veterans Affairs Medical Center
a b s t r a c t
Dissemination and implementation of evidence-based psychotherapies is challenging in real world
clinical settings. Transdiagnostic Behavior Therapy (TBT) for affective disorders was developed with
dissemination and implementation in clinical settings in mind. The present study investigated a voluntary local dissemination and implementation effort, involving 28 providers participating in a four-hour
training on TBT. Providers completed immediate (n = 22) and six-month follow-up (n = 12) training assessments and were encouraged to collect data on their TBT patients (delivery delity was not investigated).
Findings demonstrated that providers endorsed learning of and interest in using TBT after the training. At
six-months, 50% of providers reported using TBT with their patients and their perceived effectiveness of
TBT to be very good to excellent. Submitted patient outcome data evidenced medium to large effect sizes.
Together, these ndings provide preliminary support for the effectiveness of a real world dissemination
and implementation of TBT.
Published by Elsevier Ltd.
1. Introduction
Transdiagnostic treatments, or those that apply the same
underlying treatment principles across mental disorders, without tailoring the protocol to specic diagnoses (McEvoy, Nathan,
& Norton, 2009; p. 21), are based on two principles, (1) some
disorder categories have common underlying symptoms and (2)
evidence-based psychotherapy (EBP) protocols designed to address
these symptoms contain overlapping components. This may be
particularly true in the affective disorders (depressive disorders,
anxiety disorders, obsessive-compulsive and related disorders, and
trauma- and stressor-related disorders). Affective disorders have
been shown to have common underlying symptoms and so their
related disorder-specic cognitive behavioral therapy (CBT) protocols contain important, but overlapping, treatment components. It
has been suggested that these components can be distilled into a
single treatment and therefore address the symptoms and comorbidities across multiple disorders at once (Norton, 2009). To date, a
small number of transdiagnostic treatment approaches have been
proposed for the affective disorders (Norton, 2009). Although still
Corresponding author: Mental Health Service 116, Ralph H. Johnson VAMC, 109
Bee Street, Charleston, SC 29401, United States.
E-mail address: grosd@musc.edu (D.F. Gros).
in development and preliminary evaluation, early outcomes suggest that transdiagnostic approaches can be delivered efcaciously
across the affective disorders, with moderate-to-high effect sizes
(Farchione et al., 2012; Gros, 2014; Norton, 2012; Schmidt et al.,
2011).
One such example of a transdiagnostic treatment is Transdiagnostic Behavior Therapy (TBT). TBT is a newly developed
transdiagnostic psychotherapy designed to treat veterans with
affective disorders, including major depressive disorder (MDD),
panic disorder (PD), social anxiety disorder (SOC), generalized
anxiety disorder (GAD), posttraumatic stress disorder (PTSD),
obsessive-compulsive disorder (OCD), and specic phobia (SP)
(Gros, 2014). TBT stands out as the only transdiagnostic psychotherapy developed and investigated in veterans and within
the Department of Veterans Affairs (DVA). In addition, TBT also
was developed specically with ease of dissemination across DVA
providers, programs, and settings in mind. The initial data on TBT
has been quite promising with large treatment effects for veterans
with various affective disorders and comorbidities (Gros, 2014).
In addition, a large randomized control trial is currently ongoing
(Gros, 2015).
The signicance of TBT with the DVA is that the DVA is among
the leaders in the efforts to disseminate and implement EBP
protocols (Ruzek, Karlin, & Zeiss, 2012). From October 2007 to
September 2010, the DVA was responsible for training over 3800
http://dx.doi.org/10.1016/j.janxdis.2016.04.010
0887-6185/Published by Elsevier Ltd.
Please cite this article in press as: Gros, D. F., et al. A real world dissemination and implementation of Transdiagnostic Behavior Therapy
(TBT) for veterans with affective disorders. Journal of Anxiety Disorders (2016), http://dx.doi.org/10.1016/j.janxdis.2016.04.010
G Model
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D.F. Gros et al. / Journal of Anxiety Disorders xxx (2016) xxxxxx
2. Method
2.1. Training and assessment procedures
A service wide email was sent to providers at the VAMC and
afliated medical university in October 2014, soliciting interest and
availability in training in TBT. Forty-one staff and trainees replied
with interest. The training was set in December 2014 to allow time
to gain supervisor approval and block treatment clinics. The training also was tailored and set for a 4-h block based on staff/trainee
availability and permissions. On the day of the training, 28 provider
participants attended the entire training. There was no requirement
or compensation for providers to attend the training.
The training involved several sections. The rst section began
with training on the background on the transdiagnostic perspective as well as review of available transdiagnostic psychotherapies
and their support in published research. The second section covered the development and related evidence supporting TBT. Next,
Please cite this article in press as: Gros, D. F., et al. A real world dissemination and implementation of Transdiagnostic Behavior Therapy
(TBT) for veterans with affective disorders. Journal of Anxiety Disorders (2016), http://dx.doi.org/10.1016/j.janxdis.2016.04.010
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D.F. Gros et al. / Journal of Anxiety Disorders xxx (2016) xxxxxx
Table 1
Pre- to post-training provider learning in TBT initial training.
Scale
Pre
Post
Effect Size
3.6 (1.0)
3.8 (0.9)
1.7 (1.1)
2.2 (1.1)
2.0 (1.2)
1.9 (1.2)
2.0 (1.2)
1.9 (1.2)
1.8 (1.0)
3.4 (1.0)
4.0 (0.8)
3.9 (0.8)
3.8 (0.9)
3.9 (0.8)
3.8 (0.9)
3.2 (1.0)
8.2*
8.9*
9.7*
8.8*
9.6*
9.2*
6.6*
1.62
1.87
1.86
1.79
1.86
1.79
1.4
Note: EBPs = Evidence-based psychotherapies. ADs = affective disorders. Pre and post values are presented as means (standard deviations). All scales are scored on a 5 point
scale ranging from 1 to 5. Cohens ds used for effect sizes.
*
p < 0.001.
that provider participants used TBT and how much they liked TBT,
respectively. Question 3 assesses how frequently provider participants used TBT with patients with various diagnoses (e.g., MDD,
PD, PTSD, SOC, GAD, and OCD), as well as in patients with a single
diagnosis and in patients with diagnostic comorbidity. Question 4
assesses provider participants perceived effectiveness of TBT with
each disorder and presentation. Question 5 asks why provider participants did not use TBT with some or all of their patients.
2.4. Patient assessment tools
2.4.1. Depression anxiety stress scales 21-item version (DASS)
The DASS (Lovibond & Lovibond, 1995) is a 21-item measure
with three subscales designed to assess dysphoric mood (depression subscale), symptoms of fear and autonomic arousal (anxiety
subscale), and symptoms of tension and agitation (stress subscale).
Items are rated on a 4-point Likert scale, ranging from 0 to 3, and
summed to compute the three subscales. Support for the factor
structure, convergent and discriminant validity, and internal consistency of the DASS has been found (Lovibond & Lovibond, 1995).
Additional support for the internal consistency of the scales was
found in the present studies (s 0.85).
3. Results
3.1. Provider assessments
Please cite this article in press as: Gros, D. F., et al. A real world dissemination and implementation of Transdiagnostic Behavior Therapy
(TBT) for veterans with affective disorders. Journal of Anxiety Disorders (2016), http://dx.doi.org/10.1016/j.janxdis.2016.04.010
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Table 2
Reported use and success of TBT by trained providers at 6-month after training.
Disorder
Frequency of Use
Perceived
Effectiveness
2.4 (1.3)
2.7 (1.9)
2.7 (1.6)
2.4 (1.5)
2.1 (1.6)
2.8 (2.0)
2.4 (1.3)
2.4 (1.3)
3.8 (1.0)
4.3 (1.0)
4.0 (0.8)
4.0 (0.8)
3.5 (1.3)
4.7 (0.6)
3.8 (1.0)
3.8 (1.0)
Note: Values are presented as means (standard deviations). All scales are scored on
a 5 point scale ranging from 1 to 5.
but without any expectations, requirements, or incentives associated with the training. In fact, the participation in the training
and use of TBT afterwards without extrinsic incentive to do so
demonstrate the true effectiveness of the training. More specically, provider participants learned TBT and used TBT with their
patients because they simply wanted to learn it and believed that
TBT could work (better) with their patients. As such, these ndings
have excellent external validity, mirroring what could be possible
in similar settings. In contrast, DVA dissemination efforts only promoted disorder-specic EBPs for a small set of disorders, took a
full week between travel and the three day trainings as well as six
months of supervision to complete, and typically are required by
local EBP coordinators. Although outcomes are very promising in
the specic conditions/treatments under investigation (e.g., EBPs
for PTSD) (Ruzek et al., 2012), the approach in the present study
may be an easier, less expensive, and more welcoming (voluntary)
approach to train providers in EBPs pending replication and comparison studies. Moreover, in order to effectively treat the many
disorders common in psychotherapy clinics (e.g., affective disorders), training in transdiagnostic treatments allow providers to
learn only one protocol in one training, instead of a multitude of
diagnosis specic protocols across multiple trainings.
Even more surprising than the learning from and acceptance of
the training was the use of TBT by providers following the training. Without any requirement, half of the responding providers
endorsed using TBT with some of their patients across all disorders
assessed. This is particularly impressive as several of the responders
that denied using TBT, noted that their treatment setting would
not permit its use (e.g., disorder-specic EBP clinics that require
a specic treatment or non-treatment setting). And on top of that
nding, patients that received TBT demonstrated signicant treatment gains. In fact, moderate-to-large effects were seen across all
measures of psychopathology despite not all patients having the
symptoms or disorder that was assessed. For example, a large effect
was found on the DASS-Depression with only 43.8% of patients with
MDD diagnoses. The effect sizes for TBT were smaller than those in
the initial TBT study (Gros, 2014); this could be a result of the differences in exposure to and supervision of TBT between the studies
and lack of delity data in the present study. However despite the
lack of delity data, patients reported to receive TBT still demonstrated large effects compared to expected effects for the typical
treatment-as-usual for many of these conditions in the DVA (e.g.,
eclectic/support therapies).
Although the mechanisms for successful implementation are
yet unknown (Greenhalgh, Mcfarlane, Bate, & Kyriakidou, 2004),
this TBT dissemination and implementation efforts appears to have
been effective. The success in these efforts may be explained by how
the study addressed several of the common challenges in dissemination and implementation research as outlined by Weisz, Ng, and
Bearman (2014). First for the implementation cliff, TBT was developed in a DVA clinical research setting with the training of DVA
providers in mind, rather than in an academic department. Second
for the (ir)relevance of research to practice, the focus on transdiagnostic practice and goal to reduce EBPs to learn was shown to be
appealing to providers. Third for the timeline mismatch, the TBT
dissemination effort was completed prior to the completion of the
currently in-progress randomized clinical trial (Gros, 2015) to maximize its relevance to providers, versus waiting another three years
for study completion and dissemination of the ndings. And forth
for the goal tensions and the implementation limbo, this project
was an unfunded pilot/demonstration in a real world clinical setting without any nancial or time pressures, which prevented these
challenges from inuencing the dissemination and implementation
effort. Due to the success of this implementation, similar (voluntary and brief) efforts for treatments in similar settings and stages
should be considered.
Please cite this article in press as: Gros, D. F., et al. A real world dissemination and implementation of Transdiagnostic Behavior Therapy
(TBT) for veterans with affective disorders. Journal of Anxiety Disorders (2016), http://dx.doi.org/10.1016/j.janxdis.2016.04.010
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ARTICLE IN PRESS
Table 3
Efcacy of providers use of TBT with DVA patients.
Scale
Pre
Post
t (p)
Effect Size
IIRS-Impairment
PCL-5-PTSD
STICSA-T-Cognitive
STICSA-T-Somatic
DASS-Depression
DASS-Anxiety
DASS-Stress
58.1 (12.7)
48.8 (19.6)
28.1 (5.0)
23.0 (5.9)
10.9 (4.6)
9.6 (5.3)
12.9 (5.4)
42.6 (17.5)
27.0 (18.3)
20.3 (6.2)
18.9 (6.5)
4.9 (3.9)
6.0 (4.6)
7.6 (4.4)
4.3 (0.001)
3.4 (0.004)
4.3 (0.001)
2.4 (0.031)
4.9 (<0.001)
3.3 (0.005)
4.3 (0.001)
1.01
1.15
1.39
0.66
1.08
0.73
1.08
Note: Sum scores reported as means (standard deviations). Cohens ds used for effect sizes.
Acknowledgments
This study is supported by Department of Veteran Affairs Clinical
Sciences Research and Development Career Development Award
CX000845 (PI: Gros). The views expressed in this article are those
of the authors and do not necessarily reect the position or policy
of the Department of Veterans Affairs or the United States government. There are no conicts of interest to disclose. I would like to
thank the providers within the Ralph H. Johnson Veterans Affairs
Medical Center for their participation in this project.
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Please cite this article in press as: Gros, D. F., et al. A real world dissemination and implementation of Transdiagnostic Behavior Therapy
(TBT) for veterans with affective disorders. Journal of Anxiety Disorders (2016), http://dx.doi.org/10.1016/j.janxdis.2016.04.010
G Model
ANXDIS-1834; No. of Pages 6
6
ARTICLE IN PRESS
D.F. Gros et al. / Journal of Anxiety Disorders xxx (2016) xxxxxx
Please cite this article in press as: Gros, D. F., et al. A real world dissemination and implementation of Transdiagnostic Behavior Therapy
(TBT) for veterans with affective disorders. Journal of Anxiety Disorders (2016), http://dx.doi.org/10.1016/j.janxdis.2016.04.010