©2016 Stat-Ease, Inc.: What's New in Design-Expert® Version 10

Whats New in Design-Expert version 10
Presentation is posted at www.statease.com/webinar.html

There are many attendees today! To avoid disrupting
the Voice over Internet Protocol (VoIP) system, I will mute
all. Please use the Questions feature on GotoWebinar which
we will answer during the presentation.
-- Pat
Presented by Pat Whitcomb, Founder

Stat-Ease, Inc., Minneapolis, MN
pat@statease.com
April 2016 Webinar
2016 Stat-Ease, Inc.

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Computational Capability
Design Evaluation
Highlights: Recap
April 2016 Webinar
Copyright 2016 Stat-Ease, Inc. Do

not copy or redistribute in any form.

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar

User Interface
Design Wizard provides guidance for less sophisticated users

Expanded Undo/Redo option in Design Layout
Column sort from View menu for Design Layout
Run column Reorder as currently displayed option for split plots
Smoother scrolling of reports and spreadsheets
Support for different decimal point characters (localization)
LOESS Tool for Fit line in Graph Columns
Enhanced constraint tool with simplified equations and clear button
Splash screen upon start (replaces About Box)
Better handling of progress bars including threading
April 2016 Webinar
Copyright 2016 Stat-Ease, Inc. Do not

copy or redistribute in any form.

Design Wizard
April 2016 Webinar

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar


Design Build
Design Build:
Central Composite and Optimal split-plots for Response Surface
designs
Optimal split-plots for Combined (mixture-process & mix-mix) designs
Variance ratio display on the power response-entry screen for factorial
split-plots
Blocking for Definitive Screening Designs (DSDs)
Historical data choice for Combined designs
Power and sample size calculator for binomial responses during build
April 2016 Webinar

CCD Split-Plots for Response Surface
April 2016 Webinar

CCD Split Plot

Airfoil configuration DOE1
Wind tunnel experiment:
Two HTC factors:
Offset Gap
Deflection angle
Two ETC factors:
Angle of attack
Reynolds number
Gap
Wing
Deflection
1. Loosely based on: Tutorial: Industrial Split-plot Experiments, Kowalski, S.M., Parker, P. P. and Vining,
G. G., Quality Engineering, 19: 1-15, 2007.
April 2016 Webinar

CCD Split Plot
Build the Design (page 1 of 2)
1. Go to the Response Surface tab and choose a Split-Plot,
Central Composite design for four factors.
2. Enter the factor names and make the first two factors HTC:
April 2016 Webinar

10
CCD Split Plot

Build the Design (page 2 of 2)
3. Click on the Options button and
change the Alpha value to
Practical:
Click: OK and Continue>>

4. Enter the response name: Lift and click on Finish.
April 2016 Webinar
11

CCD Split Plot
Twelve Groups (whole plots)
0
0
0
0
0
0
0
00
00
0
0
0
0
-1.414
0
-1
0
0
-1
-1
-1
+1
-1
+1
-1
-1
+1
-1
+1
+1
+1
+1
+1
April 2016 Webinar

-1
-1
-1
+1
-1
+1
-1
-1
+1
-1
+1
+1
+1
+1
+1
+1.414
-1.414
+1.414
-1
12
Corn Milling
Background1 (page 1 of 2)
This experiment involves milling corn. The goal is to model the
effect of four treatment factors on the amount of grits that can be
obtained from a one-minute run of a grinding mill. The four factors
are:
1) moisture content of the corn (a),
2) roll gap (B),
3) screen size (C),
4) roller speed (D).
April 2016 Webinar
13

Corn Milling
Background (page 2 of 2)
To prepare corn for the experiment, a batch of corn (30 kg) has to
be tempered to the desired moisture content. Thus it was
decided to prepare a batch of corn to satisfy a specified
moisture content, split the batch of corn into three parts (10 kg
each), and then carry out three runs involving the other three
factors.
An RSM optimal split-plot design is selected with four factors, each
at three levels, with 30 runs. The runs were grouped into sets of
three, where each set of three had the same level of moisture.
The order of the three runs within a group is randomized and
the order of the sets of three runs is randomized.
April 2016 Webinar

14
Corn Milling
Optimal Three-Level Split Plot (page 1 of 2)
1. Go to the Response Surface tab and choose a Split-Plot,
Optimal (custom) design for four factors.
2. Enter the factor names, make the first factor HTC and make all
the factor types Discrete with 3 levels:
April 2016 Webinar
15

Corn Milling
Optimal Three-Level Split Plot (page 2 of 2)
3. Enter 7 Additional groups and 15 Additional model points:
4. Enter one response Yield:
April 2016 Webinar

16
Split-Plot Designs
In combined designs often either the process factors or the
mixture components are hard to change (HTC).
Process Factors HTC
Mixture Components HTC
April 2016 Webinar
17

Reverse Phase HPLC
Two Process Factors
Design considerations:
The mobile phase is easy to mix and change.
The column factors (particle and pore sizes) are difficult and
time consuming to change.
The experiments will be easier, faster and less costly if the mixture
components are specified as sub-plot treatments and the frying
conditions are whole-plot treatments.
Use a split-plot combined design
with Mix components as ETC
and Numeric factors as HTC.
April 2016 Webinar

18
Sweet Potato Chips

Background
Design considerations:
The soaker is large and handles lots of potato slices.
The fryers are small and it is easy to change frying
conditions.
The experiments will be easier, faster and less costly if the mixture
components are specified as whole-plot treatments and the frying
conditions are sub-plot treatments.
Use a split-plot combined design
with Mix components as HTC
and Numeric factors as ETC.
April 2016 Webinar
19

Power and Sample Size Calculator for
Binomial Responses during Build
24 Full Factorial
April 2016 Webinar

20
10

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar
21

Model Selection
Automatic Model Selection tool for choosing Criterion and Selection
method
AICc, BIC and Adjusted R-squared criteria in algorithmic selection
Select by Degree option prioritizes the criteria comparisons by term
order
Model Selection Log in Automatic Model Selection and in ANOVA
Likelihood ratio p-values for split-plot designs
Definitive Screening Designs (DSD) moved to Response Surface tab
and analyzed as a supersaturated matrix for quadratic modeling
Aliases reported and selectable in Effects List (makes Alias List
unnecessary)
April 2016 Webinar

22
11

Automatic Model Selection Tool (page 1 of 3)
April 2016 Webinar
23

Design-Expert software offers four Criterion and several Selection methods.
Criterion
Selection method
AICc
Forward & Backward
BIC
Forward & Backward
p-values
Forward, Backward & Stepwise
Adj R-Squared
All Hierarchical
For experiments with minimal collinearity all combinations of criterion and selection
method work well. However, constraints and other design abnormalities can make it
harder to determine the best model. Therefore we recommend using p-values and
backward elimination, in addition to the default of AICc and forward selection. Compare
their respective models, if they agree then youre done. If not, then try other methods
before settling on a model.
All model reduction must be guided by the

experimenter's subject matter knowledge!
April 2016 Webinar

24
12

Automatic Model Selection is used to algorithmically choose the terms to keep in the model. The Criterion
is the statistic used to make the decision for how to choose the best model. There are four choices:
AICc is the default criterion. AICc stands for Akaike's (pronounced ah-kah-ee-kay) Information
Criterion with a correction for a small design. When comparing the AICc values for two models,
the model with the smaller value is chosen.
BIC is an alternate to AICc that performs better for larger designs. BIC stands for Bayesian
Information Criterion. When comparing the BIC values for two models, the model with the smaller
value is chosen.
In general, BIC penalizes models with more parameters more than AICc does. For this reason it
generally leads to models with fewer parameters than the AICc criterion.
p-value is the traditional method looking for statistically significant terms to keep and/or
insignificant terms to remove from the model.
Adjusted R-Squared is the fourth criterion. Only All Hierarchical Subsets selection is used with
Adjusted R-Squared. This criterion may have a time-consuming search for a large set of terms.
Automatic Model Selection is not intended to replace the analyst's decisions. Please take the time to
review the results on the ANOVA and Diagnostics before using the model to make decisions.
April 2016 Webinar
25

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar

26
13

Analysis
Option to ignore groups for split-plot designs

Split-plots analyzed using either Maximum Likelihood (ML) or REML
Equations section on the split-plot ANOVA
Tolerance Intervals for predictions in split-plot designs
VIFs in split-plot ANOVA
Adjustable REML/ML stopping rule and maximum iterations
Negative variances excluded when calculating REML/ML
Variance components in mixed-models zeroed out below a threshold
Exact computation of R2 in split-plot designs
Block variance no longer included when calculating LSD values
Option to choose between one-sided and two-sided tests for intervals
New View item to see the V-matrix used in Mixed Model calculations
April 2016 Webinar
27

Maximum Likelihood (ML) or REML
April 2016 Webinar

28
14

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar
29

Diagnostics
Box-Cox plot for mixed models, e.g., split plots
Externally studentized residuals and influence graphs for mixed
models (Cook's Distance, DFFITS, Covariance Trace and Covariance
Ratio)
Control limit defaults values for DFFITs and DFBETAs with option not
to display on graph
Limit lines on diagnostic graphs labeled
Color by Group in the Residual vs Factor diagnostic graph
Footnote to Diagnostics report indicates why deletion statistics not
displayed
April 2016 Webinar

30
15
Corn Milling
An Outlier? (page 1 of 6)
Run #16 appears discrepant with the rest of the data:
Normal Plot of Residuals
Residuals vs. Predicted

4.00
Predicted vs. Actual

505
3.60426
Normal % Probability
95
90
80
70
50
30
20
10
5
2.00
500
0.00
Predicted
Externally Studentized Residuals
99
-2.00
495
-3.60426
-4.00
490
-6.00
-8.00
-8.00
-6.00
-4.00
-2.00
0.00
485
2.00
485
490
Externally Studentized Residuals
495
500
505
485
490
495
Predicted
500
505
Actual
April 2016 Webinar
31

Corn Milling
Run #16 doesnt influence the fixed effects (the model coefficients)
very much:
Cook's Distance Fixed
Leverage vs. Run
DFFITS vs. Run
1.00
0.946655
0.8
0.80
0.6
0.60
0.4
DFFITS
Leverage
Cook's Distance Fixed
1.54919
0.533333
0.40
0.266667
-1
0.2
0.20
-1.54919
0.00
13
17
21
25
29
Run Number
April 2016 Webinar

-2
13
17
Run Number
21
25
29
13
17
21
25
29
Run Number
32
16
Corn Milling
Run #16 doesnt influence the model much:
With run #16
without run #16
Yield =
Yield =
+496.52
+498.29
+1.82 * a
+1.83 * a
+0.95 * B
+0.95 * B
+2.68 * C
+2.68 * C
-0.14 * D
-0.16 * D
+2.33 * aB
+2.34 * aB
-2.26 * BD
-2.35 * BD
+3.01 * CD
+3.10 * CD
-1.70 * a2
April 2016 Webinar
33

Corn Milling
Run #16 seems to influence the random effects (the coefficient
standard errors) a lot:
Cook's Distance Random
Covariance Trace
Covariance Ratio
6.00
2.50
5.99146
5.00
Covariance Trace
1.8
Covariance Ratio
Cook's Distance Random
2.00
5
1.50
1.00
4.00
3.00
2.00
2
0.50
1.00
1
0.2
0.00
0.00
13
17
21
25
29
Run Number
April 2016 Webinar

13
17
Run Number
21
25
29
13
17
21
25
29
Run Number
34
17
Corn Milling
with run #16
without run #16
Coefficient
Standard
Estimate
Error
Source
496.52
0.49
Intercept
Source
Intercept
a-moisture
1.82
0.55
a-moisture
B-roll gap
0.95
0.55
a^2
C-screen size
2.68
0.55
B-roll gap
D-roller speed
Coefficient
Standard
Estimate
Error
498.29
0.53
1.83
0.25
-1.70
0.59
0.95
0.24
-0.14
0.55
C-screen size
2.68
0.24
aB
2.33
0.60
D-roller speed
-0.16
0.25
BD
-2.26
0.60
aB
2.34
0.27
CD
3.01
0.60
BD
-2.35
0.27
CD
3.10
0.27
April 2016 Webinar
35

Corn Milling
In this exercise including run # 16 primarily increases the residual
variance while having little effect on the model coefficients:
with run # 16
without run # 16
Variance Components
Variance Components
Source
Source
Group
Variance
0.000
Group
Variance
0.000
Residual
6.99
Residual
1.39
Total
6.99
Total
1.39
April 2016 Webinar

36
18

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar
37

Graphs
All Factors view (factor profiler) on model graphs

All Reponses choice in Numerical Optimization
Interactive LSD (least significant difference) bars
Improved flexibility in sizing and placement of flags on graphs
Show ignored values on Predicted vs Actual graphs
View menu item to turn toggle on/off the factor names on Effect plots
Useful version 9 & 10 item I didnt know about:

Can right click to add a comment to a point (run) on the diagnostic
graphs
April 2016 Webinar

38
19

All Factors
April 2016 Webinar
39

All Reponses
April 2016 Webinar

40
20

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar
41

Computation & Evaluation
64-bit version
Math engine retooled for far-faster computations
Optimal builds now run in parallel making them 3 to 17 times faster
Designs no longer limited to 32K runs
Design Evaluation:
Expanded Evaluation Report for split-plot designs
View menu item to see the V-matrix used in mixed model calculations
Power and sample size calculator for binomial response
April 2016 Webinar

42
21
Power and Sample Size Calculator

for Binomial Response
24 Full Factorial
April 2016 Webinar
43

Agenda
User Interface
Design Build
Model Selection
Analysis
Diagnostics
Graphs
Design Evaluation
Highlights: Recap
April 2016 Webinar

44
22
Design-Expert version 10
Highlights: Recap (page 1 of 2)
Design Wizard provides guidance for less sophisticated users
Multiple graphs view (factor profiler)
All Reponses choice in Numerical Optimization
Blocking for Definitive Screening Designs
Add Historical data to combined design
AICc/BIC algorithmic selection
Binomial power calculation during factorial build
64 bit version with improved multi-core support
Run optimal builds in parallel to speed up processing greatly
Support for different decimal point characters (localization)
April 2016 Webinar
45

Design-Expert version 10
Highlights: Recap (page 2 of 2)
Optimal split plots for RSM
CCD split plots
Optimal split plots for Combined designs
Half-normal plots for all 2-level split-plots
Split plots analyzed using either REML or ML
Forward selection for REML/ML analysis
Equations section on the split-plot ANOVA
Improved split-plot diagnostics (e.g. REML Box-Cox)
Ability to ignore groups for split-plot designs
Show V matrix in design evaluation
April 2016 Webinar

46
23

Reminder, this presentation is posted at:
www.statease.com/webinar.html
If you have additional questions email them to:
stathelp@statease.com
Thank you for joining us today!

April 2016 Webinar
47

24

©2016 Stat-Ease, Inc.: What's New in Design-Expert® Version 10

Caricato da

Informazioni sul documento

Titolo originale

Copyright

Formati disponibili

Condividi questo documento

Condividi o incorpora il documento

Opzioni di condivisione

Hai trovato utile questo documento?

Questo contenuto è inappropriato?

Copyright:

Formati disponibili

©2016 Stat-Ease, Inc.: What's New in Design-Expert® Version 10

Caricato da

Copyright:

Formati disponibili

Whats New in Design-Expert version 10

Presentation is posted at www.statease.com/webinar.html

Presented by Pat Whitcomb, Founder