15 November 2016

EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substance
Current Substance names and EV Codes, including new Substance names and EV Codes
Related Information:
Cover note on eXtended EudraVigilance Medicinal Product Dictionary (XEVMPD) substance controlled
vocabulary following the quality control exercise

xEVMPD Code

Substance Name

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 1 / 18

15 November 2016
EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substances
Deprecated Substance Name(s) since the last publication of the Substance CV
Related Information:
Cover note on eXtended EudraVigilance Medicinal Product Dictionary (XEVMPD) substance
controlled vocabulary following the quality control exercise

xEVMPD Code
SUB23447
SUB04930MIG
SUB11752MIG
SUB173904
SUB173905
SUB183485
SUB183486
SUB183487
SUB126920
SUB126920
SUB38371
SUB38371
SUB45638
SUB45638
SUB45638
SUB182427
SUB182427
SUB07674MIG
SUB43464
SUB07680MIG
SUB07680MIG
SUB07680MIG
SUB180105
SUB32413
SUB43736
SUB43736
SUB15028MIG
SUB00579MIG
SUB25434
SUB25434
SUB13999MIG
SUB13999MIG
SUB59292
SUB59292
SUB01834MIG
SUB01834MIG
SUB20826
SUB167585
SUB167585
SUB167586
SUB167586
SUB13315MIG

XEVMPD Substance Name

POLIDESTROSO (E1200)
TRANYLCYPROMINE SULPHATE
BITTER-ORANGE-FLOWER OIL
OPADRY 03F52057 YELLOW
OPADRY 03F52056 YELLOW
LIQUID EXTRACT OF ARNICA FLOWER
LIQUID EXTRACT OF CALENDULA FLOWER
LIQUID EXTRACT OF ST. JOHNS WORT
MILK-THISTLE FRUIT
MILK THISTLE FRUIT
WEIER TON
WEISSER TON
CERA FLAVA
CERA FLAVA
GELBES WACHS
ALN-60212
ALN-PCSSC
FLUKONASOOLI
OXATOMIDE HYDRATE
FLUDESOXIGLUCOSE [18F]
FLUORINE (18F) FLUDEOXYGLUCOSE
FLUDEOXYGLUCOSE (18F)
CABAZITAXEL ACETONE
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE (DSPC)
DRIED PRESSED JUICE FROM FRESH FLOWERING PURPLE CONEFLO
GETROCKNETER PRESSSAFT AUS FRISCHEM, BLHENDEM PURPUR
PROPYLGALLAAT (E31 0)

ENTECAVIR MONOHYDRATE
ENTECAVIR HYDRATE
HYDROXYETHYL SALICYLATE
GLYCOL SALICYLATE
POTASSIUM HYDROXYQUINOLIN SULFATE
POTASSIUM HYDROXYQUINOLINE SULPHATE
DOXYLAMINE SUCCINATE
DOXYLAMINE HYDROGEN SUCCINATE
VALERIAN
FRUIT PUNCH FLAVOUR VA93402
FRUIT PUNCH FLAVOUR FV654
MANGO FLAVOUR FV658
MANGO FLAVOUR VA93382
CHELIDONIUM

SUB15186MIG
SUB15549MIG
SUB125076
SUB170667
SUB170667
SUB120273
SUB176772
SUB176772
SUB176775
SUB176775
SUB176776
SUB09593MIG
SUB16197MIG
SUB16197MIG
SUB33502
SUB25470
SUB172450
SUB21611
SUB31120
SUB31120
SUB34751
SUB34751
SUB34751
SUB34783
SUB60575
SUB73759
SUB76185
SUB76185
SUB76185
SUB76185
SUB16380MIG
SUB16380MIG
SUB16380MIG
SUB16380MIG
SUB20488
SUB121632
SUB121632
SUB126359
SUB29050
SUB49974
SUB49974
SUB88162

SALVIA
THYMUS
ARGENTUM METALLICUM PRAEPARATUM DIL. D30
AVICEL PH-105
MICROCRYSTALLINE CELLULOSE PH-105
ATROPINE SULFATE H2O
KAMILLENBLTEN (1:1,7-2,2) AUSZUGSMITTEL: ETHANOL 45 % (
EXTRACT OF CHAMOMILLA RECUTITA (1:1,7-2,2), EXTRACTION S
AUSZGE AUS BENEDIKTENKRAUT (1:1,7-2,2) AUSZUGSMITTEL:
EXTRACT OF CNICUS BENEDICTUS (1:1,7-2,2), EXTRACTION SOL
EXTRACT OF ARTEMISIA ABSINTHIUM (1:1,7-2,2), EXTRACTION
PALONOSETRONU
SOJALETITSIINI
SOJALETSITIINI
APLIDINE
IBANDRONIC ACID SODIUM SALT, HYDRATE
OPDARY 03F34280 PINK
"BRNYHIML VRUS OKA/MERCK TRZS (L, ATTENULT)
ETHANOL 95%
ALCOHOL 95%
"ZMES FARIEB SVETLO MODR "
"BAREVN SMS SVTLE MODR "
" "
"FARBA RUOV ZMES "
SODIC CARBOXYMETHYL STARCH TYPE A(GLUTEN FREE)
"OLEJOV ALOOV EXTRAKT (OBSAHUJC SJOV OLEJ A TOKOF
KOPOLIMER ETERU METYLOWINYLOWEGO I ESTRU MONOBUTYL
METHYL VINYL ETHER/MONO-BUTYL MALEATE COPOLYMER
METHYLVINYLIC-ETHER MONOBUTYLESTER MALEIC A. COPOLYME
METHYL VINYL ESTER AND MALEIC MONOBUTYL ESTER COPOLYME
MACROGOL 400
MACROGEL 400
MACROGOL 400
POLYETHYLENE GLYCOL 400
SORBITOL EIEKLY 70% NIEKRYSTALIZUJCY
KOPOLIMER AKRYLOWY O WACIWOCIACH ADHEZYJNYCH
ACRYLKLEBSTOFF
TERTIR BUTYLALKOHOL
CITRONENSURE (WASSERFREI)
KAKAOBUTTER
COCOA BUTTER
: EXTRACTUM LIQUIDUM (1:3,5) EX PASTINACEAE FRUCTU, URTI

30 Churchill Place Canary Wharf London E14 5EU United Kingdom

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he Substance CV

http://www.ema.europa.eu/docs/en_GB/document_library/Other/2014/03/WC500162278.doc

Language

Name Type

Date of Creation

IT
EN
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
DE
N/A
LA
N/A
DE
N/A
N/A
ET
N/A
PT
N/A
N/A
N/A
N/A
EN
N/A
NL
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A

Substance Translation
Substance Translation
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name
Substance Alias
Substance Translation
Substance Alias
Substance Translation
Substance Alias
Substance Translation
Substance Alias
Substance Preferred Name
Substance Translation
Substance Preferred Name
Substance Translation
Substance Preferred Name
Substance Alias
Substance Preferred Name
Substance Preferred Name
Substance Translation
Substance Preferred Name
Substance Translation
Substance Alias
Substance Alias
Substance Preferred Name
Substance Alias
Substance Preferred Name
Substance Alias
Substance Preferred Name
Substance Preferred Name
Substance Alias
Substance Preferred Name
Substance Alias
Substance Preferred Name
Substance Preferred Name
Substance Alias
Substance Alias

3/1/2007
10/14/2004
10/14/2004
3/9/2015
3/9/2015
7/7/2016
7/7/2016
7/7/2016
10/1/2013
10/1/2013
6/1/2012
6/1/2012
6/21/2012
6/21/2012
6/21/2012
5/30/2016
5/30/2016
10/14/2004
6/18/2012
10/14/2004
10/14/2004
10/14/2004
11/19/2015
7/29/2011
6/19/2012
6/19/2012
10/14/2004
10/14/2004
6/21/2007
6/21/2007
10/14/2004
10/14/2004
7/2/2012
7/2/2012
10/14/2004
10/14/2004
8/22/2005
7/31/2014
7/31/2014
7/31/2014
7/31/2014
10/14/2004

N/A
N/A
N/A
N/A
N/A
N/A
DE
N/A
DE
N/A
N/A
SK
ET
ET
N/A
N/A
N/A
HU
N/A
N/A
SK
CS
BG
SK
N/A
CS
PL
N/A
N/A
N/A
NO
N/A
N/A
N/A
PL
PL
DE
SE
DE
N/A
N/A
N/A

Substance Alias
Substance Alias
Substance Preferred Name
Substance Preferred Name
Substance Alias
Substance Preferred Name
Substance Translation
Substance Preferred Name
Substance Translation
Substance Preferred Name
Substance Preferred Name
Substance Translation
Substance Translation
Substance Translation
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name
Substance Translation
Substance Alias
Substance Preferred Name
Substance Translation
Substance Translation
Substance Translation
Substance Translation
Substance Preferred Name
Substance Translation
Substance Translation
Substance Alias
Substance Alias
Substance Preferred Name
Substance Translation
Substance Alias
Substance Alias
Substance Preferred Name
Substance Translation
Substance Translation
Substance Translation
Substance Translation
Substance Translation
Substance Alias
Substance Preferred Name
Substance Preferred Name

10/14/2004
10/14/2004
7/30/2013
12/18/2014
12/18/2014
4/10/2013
5/27/2015
5/27/2015
5/27/2015
5/27/2015
5/27/2015
10/14/2004
10/14/2004
10/14/2004
2/24/2012
6/21/2007
2/12/2015
6/27/2006
4/2/2010
4/2/2010
5/4/2012
5/4/2012
5/4/2012
5/8/2012
7/3/2012
8/9/2012
8/30/2012
8/30/2012
8/30/2012
8/30/2012
10/14/2004
10/14/2004
10/14/2004
10/14/2004
6/7/2005
5/29/2013
5/29/2013
9/17/2013
9/17/2008
6/29/2012
6/29/2012
10/22/2012

hurchill Place Canary Wharf London E14 5EU United Kingdom

Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 7418 8447
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Website www.ema.europa.eu
An agency of the European Union

WC500162278.doc

Date of Last Update

7/14/2016
7/18/2016
7/18/2016
7/18/2016
7/18/2016
7/18/2016
7/18/2016
7/18/2016
7/21/2016
7/21/2016
7/22/2016
7/22/2016
7/22/2016
7/22/2016
7/22/2016
7/25/2016
7/25/2016
7/27/2016
8/9/2016
8/24/2016
8/24/2016
8/24/2016
8/24/2016
8/25/2016
8/25/2016
8/25/2016
9/1/2016
9/13/2016
9/14/2016
9/14/2016
9/15/2016
9/15/2016
9/16/2016
9/16/2016
9/19/2016
9/19/2016
9/19/2016
9/23/2016
9/23/2016
9/23/2016
9/23/2016
9/26/2016

9/27/2016
9/27/2016
9/29/2016
9/29/2016
9/29/2016
10/5/2016
10/5/2016
10/5/2016
10/5/2016
10/5/2016
10/5/2016
10/7/2016
10/7/2016
10/7/2016
10/10/2016
10/12/2016
10/17/2016
10/27/2016
10/27/2016
10/27/2016
10/27/2016
10/27/2016
10/27/2016
10/27/2016
10/27/2016
10/27/2016
10/28/2016
10/28/2016
10/28/2016
10/28/2016
11/3/2016
11/3/2016
11/3/2016
11/3/2016
11/3/2016
11/8/2016
11/8/2016
11/10/2016
11/11/2016
11/14/2016
11/14/2016
11/14/2016

15 November 2016
EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substances
Nullified EVCode(s) since the last publication
Related Information:

Cover note on eXtended EudraVigilance Medicinal Product Dictionary (XEVMPD) substance

http://www.ema.europa.eu/docs/en
controlled vocabulary following the quality control exercise

xEVMPD Code
SUB127162
SUB127162
SUB181302
SUB181302
SUB181302
SUB183220

XEVMPD Substance Name

Language

ISOPROPYL MYRISTAT PH. EUR

ISOPROPYLMYRISTAT (PH. EUR.)
3-DEOXY-3-(18F)FLUOROTHYMIDINE
3'-DEOXY-3'-(18F)FLUOROTHYMIDINE
ALOVUDINE F-18
BACTERIAL LYSATE FROM ENTEROCOCCUS FAECALIS DSM

N/A
DE
N/A
N/A
N/A
N/A

30 Churchill Place Canary Wharf London E14 5EU Un

Telephone +44 (0)20 3660 6000 Facsimile +44 (0)
Send a question via our website www.ema.europ
Website www.e

www.ema.europa.eu/docs/en_GB/document_library/Other/2014/03/WC500162278.doc

Name Type

Date of Creation

Date of Last Update

Substance Preferred Name

Substance Translation
Substance Preferred Name
Substance Alias
Substance Alias
Substance Preferred Name

10/9/2013
10/9/2013
2/25/2016
2/25/2016
2/25/2016
7/5/2016

9/22/2016
9/22/2016
7/20/2016
7/20/2016
7/20/2016
9/29/2016

hurchill Place Canary Wharf London E14 5EU United Kingdom

Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 7418 8447
Send a question via our website www.ema.europa.eu/contact
Website www.ema.europa.eu
An agency of the European Union

Date of Nullification
9/22/2016
9/22/2016
7/20/2016
7/20/2016
7/20/2016
9/29/2016

15 November 2016
EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substances - Implementation of the substance de-duplication

Remapping table of substance EVCodes (to be used for updating products)
Related Information:
Cover note on eXtended EudraVigilance Medicinal Product Dictionary
(XEVMPD) substance controlled vocabulary following the quality
control exercise

http://www.ema.europa.eu/docs/en_GB/document_library/O

XEVMPD Substance EVCode

(Before the Substance Quality Control)
Previous
Substance EVCode

XEVMPD Substance Name

Language

SUB00267MIG
SUB00281MIG
SUB00606MIG
SUB00657MIG
SUB00715MIG

ACETYL-GLUCOSAMINE
ACEXAMATE ZINC
ASPARTATE POTASSIUM
BALSALAZIDE SODIUM
BENZATROPINE MESILATE

N/A
N/A
N/A
N/A
N/A

Name Type
Substance
Substance
Substance
Substance
Substance

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Preferred
Preferred
Preferred
Preferred
Preferred

Name
Name
Name
Name
Name

Page 11 / 18

15 November 2016
EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substances - Implementation of the substance de-duplication

Substance EVCodes to be nullified (not remapped) not linked to products
Related Information:

Cover note on eXtended EudraVigilance Medicinal Product Dictionary (XEVMPD) substance

http://www.ema.europa.eu/docs/en_GB/
controlled vocabulary following the quality control exercise

xEVMPD Code
SUB01708MIG
SUB04071MIG
SUB119650

XEVMPD Substance Name

DI-HYDROCORTISONE PHOSPHATE
PROMETHAZINE HYDROXYETHYL CHLORIDE
FERROUS SALTS

Language
N/A
N/A
N/A

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 12 / 18

e de-duplication

ema.europa.eu/docs/en_GB/document_library/Other/2014/03/WC500162278.doc

Name Type
Substance Preferred Name
Substance Preferred Name
Substance Preferred Name

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 13 / 18

15 November 2016
EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substances - Implementation of the substance de-duplication

Substance EVCodes to be nullified (not remapped) linked to products
Related Information:

Cover note on eXtended EudraVigilance Medicinal Product Dictionary (XEVMPD) substance controlled vocabulary following the qualit

xEVMPD Code
SUB03279MIG
SUB03467MIG

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 14 / 18

ubstances - Implementation of the substance de-duplication

odes to be nullified (not remapped) linked to products

ed EudraVigilance Medicinal Product Dictionary (XEVMPD) substance controlled vocabulary following the quality control exercise

XEVMPD Substance Name

METRONIDAZOLE SODIUM
NOSCAPINE RESIN

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 15 / 18

http://www.ema.europa.eu/docs/en_GB/document_library/Other/2014/03/WC500162278.doc

Language

Name Type

N/A
N/A

Substance Preferred Name

Substance Preferred Name

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 16 / 18

30 Churchill Place Canary Wharf

Telephone +44 (0)20 3660 6

Send a question via our w

15 November 2016
EMA/136148/2012, Rev.45
Business Data and Analytics

XEVMPD Substances - Implementation of the substance de-duplication

For information: Invalid substance names no action on the EVCode should be performed based
Related Information:

Cover note on eXtended EudraVigilance Medicinal Product Dictionary (XEVMPD) substance

http://www.ema.europa.eu/docs/en_GB/
controlled vocabulary following the quality control exercise

Substance EVCode

Substance name

Language

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 17 / 18

30 Churchill Place Canary Wharf London E14 5EU United Kingdom

Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 7418 8447
Send a question via our website www.ema.europa.eu/contact
Website www.ema.europa.eu
An agency of the European Union

e de-duplication

d be performed based on this sheet

ema.europa.eu/docs/en_GB/document_library/Other/2014/03/WC500162278.doc

Name Type

European Medicines Agency, 2011. Reproduction is authorised provided the source is acknowledged.

Page 18 / 18