Documenti di Didattica
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Paul Vanouse
Paul Vanouse
America Project
Esther Klein Gallery
2016
Paul Vanouse
WITH SCIENTIFIC COLLABORATOR SOLON MORSE
Thanks To
Angela McQuillan, Curator.
Special Thanks
Millie Chen, Omar Estrada, Katya Gibel-Mevorach, Jennifer Gradecki,
Heather Dewey-Hagborg, Angela McQuillan, John Soluri, Andres TapiaUrzua, Orkan Telhan, Allison Vanouse, Donald Vanouse, Mary Vanouse,
for their stimulating questions used throughout the catalog.
Irus Braverman, Matt Caywood, Jens Hauser, Evelyn Hawthorne, Kathy
High, Joan Linder, Jamie Sanbonmatsu, Jennifer Surtees, Igor Vamos,
Melissa Vanouse, for their feedback and support.
Cover: The America Project, spittoon: Paul Vanouse; photo: Natalie DiIenno
Design: Angela McQuillan, Solon Morse
Concept
The America Project is a live, biological art installation centered around
a process called DNA gel electrophoresis, colloquially described as
DNA fingerprinting, a process which Ive appropriated to produce
recognizable images. The project premiered at the Esther Klein Gallery
on October 20, 2016.
Visitors to the installation first encountered what might resemble a
human-scale fountain or decanter, which was actually a spittoon in
which their donated spit was collected. Entering the exhibition, viewers
were offered a one ounce cup of saline solution and asked to swish for
thirty seconds, then to deposit the solution into the spittoon. During
the installation I extracted the DNA from what I hoped to be hundreds
of spit samplescontaining cheek cells and the cells DNAall mixed
together. The DNA was not individuated nor retained: it was processed as a
whole to make iconic DNA fingerprint images of powersuch as a crown,
warplanes and a flagwhich were visible as video projections of the
electrophoresis gels throughout the exhibition.
I hope that viewers reflected on some key concepts of Americasuch as the
melting pot (in this case composed of spit samples), and the notion that
power emerges from the people. Im also seeking to invert two assumptions
about DNA imaging and essential human difference by showing:
1. A coherent image can be made from mixed up/contaminated samples.
2. While much has been made of our differences, all human DNA is very
similarreinforcing my declaration of Radical Sameness that human
DNA contains only Islands of Difference in a Sea of Sameness.
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Process of Explanation
I sent the proceeding concept description of The America Project to a
dozen colleagues, family and friends and asked of them, in the spirit of
democracy and participation, if they would pose a single question about
the work that I could incorporate into this essay.
ON COLLECTING SPIT
What about the paranoia of dna as something ultra-personal and therefore
private, still dominating in the public eye?
Omar Estrada, Toronto
DNA in the public imagination has for decades been synonymous with
identity and identification. DNA fingerprinting, DNA proling and DNA
typing are among the technical terms for procedures that fix a person
to a forensic sample or to a genetic community. These techniques
evoke bold proclamations such as DNA is a truth machine and a gold
standard of criminal identification.1 Identity-fixing technologies also
provoke a reasonable concern over personal privacy. National databases
such as the US CODIS project, a database shared among federal and
civic agencies that contains the DNA profiles of over 15 million US
citizens, epitomizes the growing threat to privacy and perhaps to liberty.
However, the fear of the penetrating gaze of the surveillant state pales
in comparison to the more ominous potential use of DNA profiles to infer
group proclivities or to institute neo-eugenic imperatives: The Gattaca
scenario.2 It is no wonder that when we give blood or tissue samples
many increasingly feel a separation anxiety about their end use.
When audiences started to spit at the Sex Pistols on stage; when we kiss or
make loveWhen we share our chemistry as an act of closenessThe whole
idea of civilization is based on the practice of sharing our dna. However,
the social control of this exchange gives the master an upper-hand on
civilization.
Andres Tapia-Urzua, Pittsburgh, PA
Savvy personal genome companies, like 23andMe, have managed to
convince over two million people to not only donate their individual
DNA samples to be utilized as the company sees fit, but to actually pay
the company for the service. Conversely, The America Project does not
want to normalize nor acclimatize viewers to surrendering their fluids
for fun, safety or profit. Hopefully, the enormous spittoon doesnt
elicit blind trust. It is a symmetrical, somewhat anthropomorphic,
authoritarian-looking apparatus standing six feet tall. Ironically, the
spittoon was designed to serve as a utopian and unambiguous bio-matter
anonymizer. Everyones spit is mixed together, making separation/
individuation impossible. All collected samples merge to become
promiscuously commingled. What is visualized from the commingled
samples is our shared identity as mammals, our collectivity.
Image credit: 23andMe www.23andme.com/howitworks
America Project, Gallery visitors donating DNA, Esther Klein Gallery, Philadelphia, PA, 2016.
Photo: Jaime Alvarez
ON DIFFERENCE
How do you call up these islands of anomalies? And are they deviant elements
such as the fin becoming a foot on the ancient fish?
Donald Vanouse, Oswego, NY
Genetic differences that produce visible manifestations in organismal
bodies are much cooler but also much rarer than the majority of genetic
variation. Much of the variation in the human genome lies in regions
that dont seem to affect our survival and do not leave a trace on the body.
Mutations can proliferate in these regions without dramatic consequence,
whereas other regions in our genome that are crucial for our survival are
more highly conserved and thus vary little between individuals.
As specific subset of these genetically variable regions, called Variable
Number Tandem Repeats (VNTRs), are typically targeted in DNA typing.
Here is an example of a VNTR sequence: GATAGATAGATAGATAGATAGATA.
Note the repeating GATA unit in the sequence? Different people can
have different numbers of the repeated unit in a VNTR region. These
glitchy-looking differences in VNTR sequences have variously been
ascribed to relics of our evolutionary past or as evidence to argue for a
gene-centered, rather than an organism-centered, view of evolution, a
theoretical framework referred to as the selfish gene.6 Because VNTR
regions are so highly variable between individuals, they are good targets
for individuation using genetic technologies.
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I also assumed there were thousands of possible dna configurations possible in the
human race. Your theme suggests that its much more limited than that. How
many dna types do you suspect are possible in the general population?
Mary Vanouse, Oswego, NY
The media often conflates DNA sequencing and DNA typing. In every
cell in our bodies, there are roughly three billion base pairs of DNA
strung together in a particular sequence to form the genome: differences
between the DNA sequences found in different cells inside a single
persons body are negligible. Between individuals, DNA sequences differ
by less than one percent: we humans share about 99% of our genetic
sequence. Excepting identical twins, no two individuals are exactly the
same, but most are virtually identical.
DNA typing generally relies on targeting regions of difference, but a forensic
DNA image would typically examine only a handful of regions within the
entire genome. Historically, as few as four and as many as fifteen sites of
greatest difference between humans, primarily VNTPs, are targeted. So,
to answer your question directly, whether we find hundreds, thousands,
millions or billions of combinations depends on how many sites we
examine. While no two humans will have exactly the same DNA sequence
across the entire genome, the probability that two humans are identical
within just a small number of sites is a bit more probable.
DNA can also be imaged to highlight other, highly stable and nonvarying parts of the genome, which is what Im doing. Imaging these
highly conserved areas of the genome would primarily be useful only for
differentiating ourselves from our distant evolutionary relatives. Any of
these methods could tell us a different story about ourselves. My method
and my story emphasizes our radical sameness at the genetic level.
In The Order of Things, Michel Foucault describes intellectual thought
of what he calls the Classical Ageroughly the mid-seventeenth to
eighteenth centuriesas characterized by ordering, identity and difference,
which gave rise to categorization and taxonomy. Naturalists of the
Classical Age were fixated on a model of living organisms as exhibiting
essential differences that could be grouped and charted.7 I believe that this
is a world-view which still lingers. Im suggesting a model of difference as
a tentative emergence from a sea of relative sameness.
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Degenerated Crown, live projection, Esther Klein Gallery, Philadelphia, PA, 2016.
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I agree that while the site and scale of observation in the life sciences over
the centuries has shifted from the organism to DNA molecules, all the
dogmas and grand narratives have been written from a human perspective.
It is only recently that we have begun to consider the philosophical and
ethical implications of expanding the circle of moral concern and extending
subjectivities beyond the human species, a project characterized as
Posthumanism. For instance, the recent microbiome craze, based around
the fact our bodies contain far more bacterial than human cells, seems to be
creating more nuanced understandings of symbiotic and parasitic organisms
and complicating our human essence and subjectivity. More ominously, the
discovery of proteins like the prions responsible for mad cow disease offers
a whole new window into the dynamic behavior of non-living molecules.
These prions directly influence the form of other proteins in the host,
causing an exponential cascade of misfolded proteins leading to brain rot.
With an earlier project Ocular Revision (2010), I was suggesting other
scales of observation. I was also trying to underscore that DNA was
a material substancedeoxyribose nucleic acidnot limited to any
particular life form, nor some sort of cybernetic command code. In Ocular
Revision, I made images of the Earths hemispheres from a mixture
of DNA obtained from Escherichia coli bacteria and lambda phage virus.
This DNA was processed to generate a range of fragment sizes that were
combined and inserted into a circular electrophoresis apparatus to create
the images. By asserting DNA as a very physical medium with distinct
material properties, Ive tried to dissociate the notion of DNA as an
informatic code belonging to an organism and to reconnect it to the vast
chemical and material realm that is enmeshed in the fabric of life.
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PROCESS/TECHNIQUE
From my laypersons point of view, why would a pure sample produce a
coherent (cultural) image that resonates outside of a biotechnical context?
John Soluri, Pittsburgh, PA
As I try to picture your installation in the theater of my head, I notice that the
part of me that knows the national anthem would be tempted to apply that
naive reading, national-character-through-individual-difference, with a
kind of magical thinking This is partly because it seems like the collection of
samples is an unnecessary step or a red herring: couldnt you produce the image
without collecting so many samples?
Allison Vanouse, Boston, MA
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Notes
1
See Michael Lynch, Simon A. Cole, Ruth McNally and Kathleen Jordan, Truth
Machine (University of Chicago Press, Chicago, 2008).
See Gattaca: A 1997 American science fiction film written and directed by Andrew
Niccol, starring Ethan Hawke and Uma Thurman. It portrays a eugenic future in
which social roles and employment are dictated by perceived genetic fitness.
See Natalie Angier, Do Races Differ? Not Really, DNA Shows, New York Times
(August 22, 2000).
Katya Gibel Mevorach, Interpreting the Census: The Elasticity of Whiteness and
the Depoliticization of Race, Racial Liberalism and the Politics of Urban America, Ed:
Curtis Stokes, Theresa A. Melendez (Michigan State University Press, East Lansing,
2007) p. 155.
While Eadweard Muybridges motion studies were conducted prior to the Eugenics
movement, the appropriation of his figures in the work was intended to invoke the
idea of applying the visual technologies of the time to measurement of man.
See The Selfish Gene, Richard Dawkins, (Oxford University Press, 1976). Dawkins
argues for a gene-centric, rather than organism-centric model of evolution in which
fitness might best be understood in relation to a specific genes proliferation. His
argument is not without its detractors, in particular surrounding questions of moral
behavior
See Michel Foucault, Order of Things, (Random House, New York, 1971).
See Idiocracy: a 2006 American science fiction comedy film directed by Mike Judge
depicting the future US in which selective breeding has happened in reverse. Set in
2050, humans live an Orwellian, social Darwinist nightmare of imbecile citizens and
corporate-powered totalitarianism.
10
See PCR Troubleshooting and Optimization, Susanne Kennedy and Nick Oswald
(Caister Academic Press, Norfolk, 2011).
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