Name

Diagnosis
Physician
DRUG DATA

Age:

CLASSIFICATION

MECHANISM OF
ACTION

Generic Name:
Tobramycin +
dexamethasone

Therapeutic: antibiotic;
corticosteroid
respectively

Trade Name:
Tobradex

Pregnancy risk
category: Category C

Patients Dose: 1
squirt qid to
affected area

Pharmacologic:
aminoglycoside, steroid

Pharmacokinetics:
*not absorbed
systemically
Onset: unknown
Peak:30 min.;
unknown
Duration: unknown
Half-life: 2-3 hrs;
unknown

Minimum Dose: 1
squirt qid
Maximum Dose: 2
squirts q4hrs; not
greater than 20ml
Available Forms:
ophthalmic
suspension
Route of
Administration:
ophthalmic

Ht:

Sex:
Date of Admission:

Chemical:
Tobramycin inhibits
protein synthesis by
binding directly to 30S
subunit of the
ribosomal unit;
generally bactericidal
Dexamethasone
suppresses edema,
fibrin deposition,
capillary dilation,
leukocyte migration,
capillary proliferation,
and collagen deposition

INDICATION
General:
-prevent or treat eye
infections
-immunosuppresant
Patients:
reduce swelling of right
eye and treat or
prevent further
infection

Wt:
Body Type:

CONTRAINDICATIONS

ADVERSE REACTIONS

Contraindicated in
patients:
-hypersensitive to the
drug or any other
aminoglycoside
*use cautiously in
patients with past
medical history of
eye problems (e.g.,
glaucoma)

-Eye redness, eye

Interactions:
Tobramycin
Dimenhydrinatemay mask symptoms of
ototoxicity
Acyclovir,
amphotericin B,
cephalosporins,
vancomycin and other
amino glycoside- may
increase nephrotoxicity
loop diuretics- may
increase ototoxicity
general anestheticmay increase
neuromuscular blockade
No significant
interactions for
Dexamethasone

discomfort, and
eyelid
itching/swelling may
occur
-Use of this
medication for
prolonged/repeated
periods may result in
a new fungal eye
infection and may
increase your risk for
other eye problems
(e.g., glaucoma,
cataracts)
-A very serious
allergic reaction to
this drug is unlikely,
but seek immediate
medical attention if it
occurs. Symptoms of
a serious allergic
reaction may include:
rash, itching/swelling
(especially of the
face/tongue/throat),
severe dizziness,
trouble breathing

NURSING
RESPONSIBILITIES
Before:
1.Check doctors
order
2.Assess whether
patient is
contraindicated to
the drug
3.Prepare
medication ahead
of time
4.Verify drug, dose,
route, timing and
pt.s identity
5.Explain procedure
to pt.
During:
1.Administer on
right route
2.Check if patient is
wearing contact
lenses, remove if
there is
3.Tilt pt.s head back
4.Hold dropper
directly above the
eye and
administer 1 drop
5.Repeat the steps
to the other eye
After:
1.Educate pt. about
possible adverse
reactions
2.Instruct pt to
report any
unusual reaction
3.Chart accordingly

4.Let pt. look

downward and
close eyes for 1-2
min.
5.Let pt. apply
gentle pressure to
the corner of the
eye