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Is carrying by the blood of various bodies (emboli) to a site distant from the point to the
origin(path.physio).
Detached intravascular solid, liquid, or gaseous mass that is carried by the blood to a site distant
from its point of origin (path. Anatomy).
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10. The typical deviation of the main constants of oxygenation status is case of circulatory
hypoxia are:
a) HbO2A : - Normal
b) HbO2V: Decreased
c) AVD: (AVS?): Increased
d) O2A: Normal, or increased
11. The rapid and effective compensatory mechanisms of hypoxia are(3):
a) Respiratory: hyperventilation and enlargement of lung surface
b) Tissue mechanisms: anaerobic glycolysis
c) Haemodynamic: increase of cardiac minute volume, Increase of blood vessel tone and
blood circulation, Centralisation of blood circulation, and Mobilization of blood from
depot organs
12. The venous hyperemia is: An increase of organ or tissue blood filling due to inadequate
venous drainage.
13. The ischemia means: Limiting of arterial blood inflow and local deficiency of the blood. Low
metabolism, local hypothermia.
14. The red thrombus consist from: white thrombus (thrombocytes and leukocytes) +
erythrocytes and fibrin.
15. The arterial hyperemia is: Increasing of an organ blood supply due to excessive blood inflow
from the arterial vessels and increase of the number of functioning capillaries.
16. The typical deviations of the main constants of oxygenation status of hystotoxic hypoxia
are:
a) HbO2A: Normal
b) HbO2V: Increased
c) AVD: Decreased or 0
d) O2A: Normal
17. The central limb of pathogenesis in case of hypoxic hypoxia is: Diminishment of partial
pressure of oxygen in the inhaled air. In other words, is a result of insufficient oxygen
available to the lungs. A blocked airway, drowning, or reduction in partial pressure (higher
than 10.000 feets) are examples of how this can occur.
18. The exogenous ethiological factors of inflammation are:
a) Physical
b) Chemical
c) Mechanical
d) Biological
19. SIRS: Definition and main characteristics of pathogenesis: Systemic inflammatory response
syndrome is an inflammatory state affecting the whole body, frequently a response of the
immune system to infection, but not necessarily so. It is related to sepsis, a condition in
which individuals both meet criteria for SIRS and have a known or highly suspected infection.
20. The physio-chemical changes in the inflammation focus are (6):
a) Acidosis
b) Hyperionia
c) Disionia
d) Hyperosmia
e) Hyperoncia
f) Hyperthermia
21. Exudation (definition): Exudation is the movement of fluid part of blood and proteins to
inflammation tissue through the change blood vessel wall. Exudation is stimulated by:
increased permeability of blood vessels, decreased in capillary colloidal pressure, increase in
focus of inflammation colloidalosmotic pressure, as fluid moves out of the blood vessels,
stagnation of flow an clotting of blood occurs at the site of injury, disturbances of lympha
retention.
22. Write the correct values in the table!
Exudate
Transudate
pH
5,5-7,0
7,4-7,6
Density
1,015 1,027
1,010 1,015
Proteins
>3,0%
< 3%
Albumins
Fibrine
is present
Not present
>3000/mm3
<3000/mm3
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chemotactix for monocytes for differentiation into macrophages (at site of inflammation)
low level of TNF causes: loss of appetite and weight, tiredness and fever
humoral type reaction (IL-3, IL-5, IL-6, IL-7, IL-9, IL-10, IL-13, TGF-beta)
cellular type reaction (IL-1, IL-2, IL-3, IL-4, IL-7, IL-9, IL-10, IL-12, IFNs)