MEDICAL

CONSTELLATIONS
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MEDICAL CONSTELLATIONS

Contents
CHROMOSOMES ................................................................................................................................................................................................................................................. 2
CIRCLES ................................................................................................................................................................................................................................................................. 6
NAMED DISEASES ............................................................................................................................................................................................................................................. 7
LAWS ................................................................................................................................................................................................................................................................... 12
MANEUVRER .................................................................................................................................................................................................................................................... 15
LOCATION OF RECEPTORS......................................................................................................................................................................................................................... 17
SIGNS ................................................................................................................................................................................................................................................................... 20
SYNDROMES ..................................................................................................................................................................................................................................................... 28
TESTS................................................................................................................................................................................................................................................................... 54
TRIADS AND PENTADS ................................................................................................................................................................................................................................ 67
TRIANGLES........................................................................................................................................................................................................................................................ 75
VERTEBRAL LEVELS ..................................................................................................................................................................................................................................... 80

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CHROMOSOMES

MEDICAL CONSTELLATIONS

CHROMOSOMES
CHROMOSOME 1
Alzheimers Disease (Presenilin 2, PS 2)
Steroid Resistant Nephrotic Syndrome NPHS2 (Podocin)
Neuroblastoma(1p Deletion)
Rh antigen
CHROMOSOME 2
Unipolar Depression
CHROMOSOME 3
Renal Cell Carcinoma
Clear Cell Carcinoma 3p deletion
CHROMOSOME 4
Huntington Chorea (Huntingtin)
CHROMOSOME 5
Familial Adenomatous Polyposis (APC Gene 5q)
MC Cytogenetic change in Myelodysplastic Syndrome Deletion of 5q
CHROMOSOME 6
Major Histocompatibility Complex
Myelodysplastic Syndrome in Adults 6q Deletion
CHROMOSOME 7
Pendred Syndrome 7q
Cystic fibrosis (CFTR gene)
Myelodysplastic Syndrome in children (Monosomy 7)
Familial Renal Papillary Carcinoma (Trisomy 7)

CHROMOSOME 9

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CHROMOSOMES

MEDICAL CONSTELLATIONS
SUPERFICIAL PAPILLARY BLADDER CANCER(9p DELETION)
CHROMOSOME 11
WAGR Syndrome (11p13 Deletion)
Beckwidth Wiedmann Syndrome (11p15 Deletion)
Ataxia Telangiectasia Gene AT
Gene For -Chain of Hemoglobin

CHROMOSOME 13
Wilsons Disease (ATP7B)
Retinoblastoma (13q14 deletion)
Osteosarcoma
Patau Syndrome
Friedrichs Ataxia (Frataxin)
Multiple Myeloma 13q Deletion
BRCA 2

CHROMOSOME 14
Alzemiers Disease (Presenilin 1,PS 1)
Chromosome affected in Ataxia Telangiectasia (Breaks)
Multiple Myeloma (14q Translocation)

CHROMOSOME 15
Development of Diaphragm 15q
Prader Will Syndrome (15q deletion)
Angelmann syndrome
Marfans syndrome
CHROMOSOME 16

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CHROMOSOMES

MEDICAL CONSTELLATIONS
Gene For -Chain of Hemoglobin
Adult Polycystic Kidney disease APKD gene

CHROMOSOME 17
BRCA 1
P53
NF1
Medulloblastoma 17q Duplication
Invasive Bladder Cancer(17p Deletion)
CHROMOSOME 18
Bipolar Disorder 18q
Edward Syndrome
CHROMOSOME 19
Alzheimers Disease (apo E4)
Nephrotic Syndrome (Finnish)

NPHS 1(Nephrin)

CHROMOSOME 21
Alzheimers Disease (APP-Amyloid Precursor Protein)
Downs syndrome
Folate Cofactor Biosynthesis

CHROMOSOME 22

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CHROMOSOMES

MEDICAL CONSTELLATIONS
DIGEORGE SYNDROME (22q11 deletion)
Bipolar Disorder 22q
NF2
Cats eye Syndrome
Meningioma 22q12 deletion (MC)
CHROMOSOME X
Androgen Receptors (Long arm)
CHROMOSOME Y
SRY GENE (SHORT ARM)

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CIRCLES

MEDICAL CONSTELLATIONS

CIRCLES
CIRCLE OF PAIN (CORONA MORTIS)
Vascular ring formed by Common Iliac artery, External Iliac artery, Obturator artery, Aberrant Obturator artery,
Inferior Epigastric Artery

CIRCLE OF WILLIS
ANTERIOR CEREBRAL ARTERY
ANTERIR COMMUNICATING ARTERY
INTERNAL CAROTID ARTERY
POSTERIOR CEREBRAL ARTERY
POSTERIOR COMMUNICATING ARTERY

CIRCLE OF HEBRA
ANATOMICAL CIRCLE ENCOMPASSING AXIAL,ELBOW FLEXURES,WRISTS,HANDS,GENITAL REGION
SITE OF PREDILECTION FOR SCABIES

CIRCLE OF IRIS
GREATER ARTERIAL CIRCLE OF IRIS ROOT OF IRIS
LESSER ARTERIAL CIRCLE OF IRIS PUPILLARY MARGIN OF IRIS

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MEDICAL CONSTELLATIONS

NAMED DISEASES
Hartnup disease
Defect in Membrane transpot mechanism of aminoacids like tryptophan

Leiners disease
Deficiency of Biotin

Burning foot disease

Deficiency of Pantothenic acid

Keshan disease
Endemic Cardiomyopathy
Deficiency of Selenium

Kaschinbeck disease
Endemic Degenerative Osteoarthropathy
Selenium Deficiency

Vagabond Disease
Pediculosis Corporis
Treatment of choice
Disinfection of clothes with 1% GBHC
DOC 1-5% Permethrin/0.5% Malathion

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NAMED DISEASES

MEDICAL CONSTELLATIONS
Dowling degos disease

Asymptomatic post pubertal symmetric progressive reticular pigmentation involving flexural areas with scattered
comedone like lesion (dark dot follicles)

Coats disease
Retinal telangiectasia
Exudative RD
Boys, unilateral

Eales disease
Perivasculitis of retina
Donot cause optic neuritis
Idiopathic inflammation of peripheral retinal vein
Bilateral
Young males
Recurrent vitreous hemorrhage
Sudden appearance of floaters

Stills disease
Systemic juvenile chronic arthritis
Juvenile rheumatoid arthritis

Blount disease (tibia vara)

Varus
Internal Rotation of Tibia
Genu recurvatum (Backward Bending)

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NAMED DISEASES

MEDICAL CONSTELLATIONS
Caffeys Disease
Infantile Cortical Hyperostosis
Periosteal New Bone Formation
Cotical Thickening of Underlying bone
MC site Mandible
Before 5 months of age

Jod Basedow Disease

Iodine Induced Hyperthyroidism

Wolman Disease
Lipid Storage disorder
Failure to Thrive
Vomiting, Diarrhoea, Hepatomegaly, Adrenal Calcification

Shone Complex
Coarctation of aorta
Left Sided Heart Lesions

Canavan Disease
Associated with Macrocephaly

Milroy disease
Familial version of congenital lymphedema

Meiges disease
Familial version of precox primary lymphedema (1-35 years)

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NAMED DISEASES

MEDICAL CONSTELLATIONS

Mondors disease
Thrombophlebitis of superficial veins of anterior chest wall and breast
Cord like appearance of subcutaneous veins

Marions disease
Muscular hypertrophy of internal sphincter of urinary bladder

Peyronies disease
Penile fibromatosis
Fibrous plaques in corpora cavernosa
Pain & curvature of penis
Associated with palmar & plantar fibromatosis

Van buchem disease

Progressive osteosclerosis in skull & mandible
Facial distorsions
Compression of cranial nerves

Lou Gehrig disease

Amyotrophic lateral sclerosis
Atrophic weakness of hands & forearm
Slight spasticity of legs
Hyperreflexia
Normal sensory system

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