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A dieta tem papel essencial na oferta de nutrientes antioxidantes, que possam modular
o equilbrio entre radicais livres e compostos antioxidantes no organismo. O estudo de
Galn et al.14 suplementou 320 idosos praticantes de atividade fsica com
antioxidantes provenientes dos alimentos, e verificou que a suplementao promoveu
melhora no risco de desenvolvimento de doenas cardiovasculares, alm de prevenir o
estresse oxidativo induzido pelo exerccio. Desta forma, a soja, por ser rica em
antioxidantes, capaz de aumentar a proteo contra o estresse oxidativo15,16. Sendo
assim, alm de ser uma importante fonte da protena da soja, Supra Soy fonte de
algumas vitaminas e minerais, o que indica um potente poder antioxidante de sua
Alm dos importantes efeitos da soja, vitaminas e minerais como zinco, cobre,
magnsio e outros antioxidantes, presentes na soja e alimentos derivados, possuem
efeito antioxidante31-34, modulando o sistema imune e exercendo ao antiinflamatria,
protegendo assim o organismo contra o estresse oxidativo causado pelo estilo de vida
GOCHMAN, E.; REZNICK, A.Z.; AVIZOHAR, O. et al. Exhaustive exercise modifies oxidative stress in
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PEAKE, J.M.; SUZUKI, K.; COOMBES, J.S. The influence of antioxidant supplementation on markers of
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ALDRED, S. Oxidative and nitrative changes seen in lipoproteins following exercise. Atherosclerosis;
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inflammation and the relationship to oxidative stress after exercise. J Nutr Biochem; 18(6):357-71, 2007.
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Washington: The Institute for Functional Medicine, 1998.
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HOWE, L.R. Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer.
Breast Cancer Res; 9(4):210, 2007.
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HUSSAIN, S.P.; HARRIS, C.C. Inflammation and cancer: an ancient link with novel potentials. Int J Cancer;
121(11):2373-80, 2007.
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BUCOVA, M.; BERNADIC, M.; BUCKINGHAM, T. C-reactive protein, cytokines and inflammation in
cardiovascular diseases. Bratisl Lek Listy; 109(8):333-40, 2008.
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DONATH, M.Y.; SCHUMANN, D.M.; FAULENBACH, M. et al. Islet inflammation in type 2 diabetes: from
metabolic stress to therapy. Diabetes Care; 31 (Suppl 2):S161-4, 2008.
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KING, G.L. The role of inflammatory cytokines in diabetes and its complications. J Periodontol; 79(8
Suppl):1527-34, 2008.
10. ISPIRLIDIS, I.; FATOUROS, I.G.; JAMURTAS, A.Z. et al. Time-course of changes in inflammatory and
performance responses following a soccer game. Clin J Sport Med; 18(5):423-31, 2008.
11. PARSONS, J.P.; BARAN, C.P.; PHILLIPS, G. et al. Airway inflammation in exercise-induced bronchospasm
occurring in athletes without asthma. J Asthma; 45(5):363-7, 2008.
12. MILES, M.P.; ANDRING, J.M.; PEARSON, S.D. et al. Diurnal variation, response to eccentric exercise, and
association of inflammatory mediators with muscle damage variables. J Appl Physiol; 104(2):451-8, 2008.
13. LELLI, J.L.; BECLS, L.L.; DABROWSKA, M.I. et al. ATP converts necrosis to apoptosis in oxidant-injured
endothelial cells. Free Rad Biol Med; 25(6): 694-702, 1998.
14. GALN, A.I.; PALACIOS, E.; RUIZ, F. et al. Exercise, oxidative stress and risk of cardiovascular disease in
the elderly. Protective role of antioxidant functional foods. Biofactors; 27(1-4):167-83, 2006.
15. SPADAFRANCA, A.; ERBA, D.; FOTI, P. et al. The consumption of soy products positively affects DNA
resistance to oxidative stress in healthy subjects. Nutr Metab Cardiovasc Dis; 18(9):e45-6, 2008.
16. MALENCIC, D.; POPOVIC, M.; MILADINOVIC, J. et al. Phenolic content and antioxidant properties of
soybean (Glycine max (L.) Merr.) seeds. Molecules; 12(3):576-81, 2007.
17. TANG, J.E.; PHILLIPS, S.M. Maximizing muscle protein anabolism: the role protein quality. Curr Opin Clin
Nutr Metab Care; 12(1):66-71, 2009.
18. DEIBERT, P.; KONING, D.; SCHMIDT-TRUCKSAESS, A. et al. Weight loss without losing muscle mass in
pre-obese and obese subjects induced by a high-soy-protein diet. Int J Obes Relat Metab Disord;
28(10):1349-52, 2004.
19. JOHNSON, F.; GIULIVI, C. Superoxide dismutases and their impact upon human health. Mol Aspects Med;
26(4-5):340-52, 2005.
20. KEEN, C.L.; GERSHWIN, M.E. Zinc deficiency and immune function. Annu Rev Nutr; 10:415431, 1990.
21. IBS, K-H.; RINK, L. Zinc-altered immune function. J Nutr; 133: 1452S1456S, 2003.
22. PERCIVAL, S.S. Copper and immunity. Am J Clin Nutr; 67(suppl): 1064S8S, 1998.
23. PRASAD, A.S. Effects of zinc deficiency on Th1 and Th2 cytokine shifts. J Infect Dis; 182: S62S68, 2000.
24. MAZUR, A.; MAIER, J.A.M.; ROCK, E. et al. Magnesium and the inflammatory response: Potential
physiopathological implications. Arch Biochem Biophys; 458: 4856, 2007.
25. BERNARDINI, D.; NASULEWIC, A.; MAZUR, A. et al. Magnesium and microvascular endothelial cells: a role
in inflammation and angiogenesis. Front Biosci; 10:1177-82, 2005.
26. SONG, Y.; RIDKER, P.M.; MANSON, J.E. et al. Magnesium intake, C-reactive protein, and the prevalence of
metabolic syndrome in middle-aged and older U.S. women. Diabetes Care; 28(6):1438-44, 2005.
27. KING, D.E.; MAINOUS, A.G.; GEESEY, M.E.; WOOLSON, R.F. Dietary magnesium and C-reactive protein
levels. J Am Coll Nutr; 24(3):166-71, 2005.
28. AZADBAKHT, L.; KIMIAGAR, M.; MEHRABI, Y. et al. Soy consumption, markers of inflammation, and
endothelial function: a cross-over study in postmenopausal women with the metabolic syndrome. Diabetes
Care; 30(4):967-73, 2007.
29. HALL, W.L.; VAFEIADOU, K.; HALLUND, J. et al. Soy-isoflavone-enriched foods and inflammatory
biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol
production. Am J Clin Nutr; 82(6):1260-8, 2005.
30. RYAN-BORCHERS, T.A.; PARK, J.S.; CHEW, B.P. et al. Soy isoflavones modulate immune function in
healthy postmenopausal women. Am J Clin Nutr; 83(5):1118-25, 2006.
31. PRASAD, A.S.; BAO, B.; BECK, F.W. et al. Antioxidant effect of zinc in humans. Free Radic Biol Med; 37:
1182-1190, 2004.
32. WALSTON, J.; XUE, Q.; SEMBA, R.D. et al. Serum antioxidants, inflammation, and total mortality in older
women. Am J Epidemiol; 163(1):18-26, 2006.
33. HUGHES, D.A. Effects of dietary antioxidants on the immune function of middle-aged adults. Proc Nutr Soc;
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34. BOX, W.; HILL, S.; DISILVESTRO, R.A. Soy intake plus moderate weight resistance exercise: effects on
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