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REVILLA]
Ventilation(V), Perfusion(Q) and V/Q relationship
=(760-47) x 0.21
=149.73 150 mmHg
From 159, oxygen pressure is now 150
fx
TV
0.7
1.0
Where:
= minute ventilation
f= frequency of respiration
TV=tidal volume
PCO2
Alveolar ventilation
Ambient air to the alveoli
2 important principles:
1
The sum of the partial pressure of a gas must be
equal to the total pressure
(100%=100%)
Average
760x 0.78=592.8 N2
760x 0.21=159.6 O2
760x 0.01= 7.6 Argon and other gases
= 760 mmHg total
pH
HCO3
pCO2
7.4
24
40
7.35-7.45
22-26mEq/l
35-45 mmHg
Example:
pH- 7.54 increased (alkalosis)
HCO3 - 30 mEq/l increased (metabolic alkalosis)
pCO2 - 33 mmHgdecreased (respiratory alkalosis)
PO2- 60 hypoxic
Answer: metabolic and respiratory alkalosis, with hypoxemia
3.
-
4.
-
Distribution of ventilation
*ventilation is not uniformly distributed in the lung due to
gravity
*alveoli near the apex
-intrapleural more negative
-alveoli larger, less complaint more expanded
-less ventilation
*alveoli near base
-alveoli smaller, more compliant
-more ventilation
*Memorize
Note takers:
Becky Abegail Chomapoy
Efigenia Gina Peralta