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founding partners of a boutique ad agency, Kirshenbaum and Bond. Marchetto moved on after a few
years to Young & Rubicam, another Madison Avenue powerhouse, which gave her a plum senior vice
president position.
Marchetto began to channel some of her creative energy into a cartoon strip whose main character
served as her alter ego. Known only as "She," the strip's stylish heroine was an executive at a large
advertising agency, but often felt unsure about the choices she had made in her life. Oftentimes she
struggled with what to wear, too, and the strip's fashion-conscious underpinnings brought it to the pages
of Mirabella , the women's magazine, where it became a regular feature in 1993. Marchetto eventually
decided to take a leave of absence from her job in order to work on a book project, and produced Just
Who the Hell Is She, Anyway? The Autobiography of She . The 1994 graphic novel featured the same
"She" heroine of the Mirabella strip, and the title was a sly pun on the highly competitive Manhattan
circles in which Marchetto ran as well as to the unfolding identity crisis that serves as a plot. Karal Ann
Marling, reviewing this debut for the New York Times , asserted that "Acocella is a tart critic of pop culture,
taking deadly aim at a variety of icons and anti-icons."
Marchetto never returned to her job at Young & Rubicam. She took freelance advertising jobs to make
ends meet while continuing to create witty, contemporary cartoons, and also spent some time developing
a television series based on She . Her ideas for a career woman who wore extremely short miniskirts and
was plagued by fantasies of her yet-to-be born child were further complicated, however, by input from
others involved in the project, and she walked away from the possibly lucrative, but never-produced
series altogether when it started to become "a hodgepodge of everyone's opinion" as she explained in an
interview with Print magazine. A few of her original ideas seemed to have made their way around
Hollywood and eventually wound up coming to screen life via the title character of the FOX television
series Ally McBeal . The show featured an attorney who sported micro-minis and was taunted by
hallucinations of a computer-generated image of a dancing baby when it debuted in 1997, which
Marchetto told the Print interviewer seemed an "unreal coincidence."
For most cartoonists, making it into the New Yorker represents the pinnacle of career achievement.
Marchetto was fortunate to find a supportive mentor in Robert Mankoff, the cartoon editor for the weekly,
and he encouraged her to perfect her skills in drawing the one-liner, single-panel cartoon jokes that are a
hallmark of the New Yorker pages. As she recalled in the interview with Print , Mankoff told her, "'If you
want to make money, stay in advertising. But at the end of the day, it's what you'll have accomplished in
life: You can have a book [of published work] or you can have a bunch of ad campaigns.'"
Marchetto finally made it into the pages of the New Yorker in 1998 with cartoons that deftly satirized a
certain milieu of affluent Manhattanites. Writing in the New York Times Book Review , Ariel Levy noted
that Marchetto "specializes in droll depictions of joyless, emaciated women in four-figure outfits," while
other critics found them to be a cartoon version of the quartet of characters in the hit HBO series Sex and
the City . "Like the series, Acocella's work goes beyond the gag to reveal among its characters a little bit
more: a glimmer of an empty emotional undercurrent, or a rippling of confusion about what the world
expects of them," claimed the Print contributor.
After a stint drawing a weekly strip for the New York Times Sunday Styles section, and then as an
illustrator for the short-lived Talk magazine, Marchetto inked a deal as the resident cartoonist for Glamour
in 2002. She had also settled into a long-term relationship with New York City restaurateur Silvano
Marchetto, owner of Da Silvano. The downtown eatery opened in 1975 and was one of first to popularize
Northern Italian cuisine in the city. The couple had met on 9/11, when Marchetto showed up for a
previously booked lunch table at the restaurant; the city was in chaos and much of downtown covered in
dust and debris, but the owner fed her anyway. They began dating and were counting down the three
weeks to their wedding in the spring of 2004 when Marchetto discovered a lump in her breast. She feared
her fianc might leave her, she told Newsweek 's Nicki Gostin, because "I always thought in a relationship
a woman had to be perfect all the time and breast cancer is definitely a major imperfection."
But the Acocella-Marchetto wedding went ahead as planned, and the new bride soon embarked on a
demanding course of treatment that included surgery, chemotherapy, and radiation treatments. Dismayed
by the term "cancer victim," she took to calling herself "cancer vixen" instead, and began drawing about it
an offshoot of the extensive notes she usually took when meeting with her medical team to discuss
treatment options and progress. There was one physician, however, who discouraged her from drawing
cartoons of her experiences. "He thought that I was making light of something that was serious and said it
was a bad idea," she told New York Times writer Lola Ogunnaike. "Needless to say, I never went back to
him."
Cancer Vixen made its public debut as a six-page cartoon feature in Glamour magazine in April of 2005,
and the full-length book version was published by Knopf in the fall of 2006. It won a slew of good reviews,
with most critics praising Marchetto for her candor and ability to see a difficult situation with humor.
Writing in the Houston Chronicle , Helen Ubinas asserted the author "has created an absorbing and
inspiring tale of a woman who knows how to do thingseven fight cancerin style. And who comes
away with a better understanding of herself, her surroundings and the joy of slowing down just enough to
enjoy life."
The New York Times Book Review 's Levy found that "Marchetto's sunny drawings comfort and amuse
while providing a beneficial education on cancer's dark details." In a New York Observer article, Toni
Schlesinger contended that "the genius of the book lies partly in the perfect depictions of the author's
eclectic media circle, but mostly in the emotional drawings, the terror on the protagonist's face during a
chemotherapy treatmentthe drugs aren't going into the vein, her drawing hand and arm go numb, her
mother is screaming." Warm praise came from abroad, too, with a fellow author and breast-cancer
survivor, Stella Duffy, writing in London's Guardian that Marchetto "draws an honest sadness, but she
does so with humor and self-deprecation, the polar opposite of those ghastly tabloid 'my brave battle'
cancer stories."
Duffy made mention of some of the differences between the British health-care system, in which everyone
is covered by government-subsidized medical care, and the U.S. private-insurance scheme; in Cancer
Vixen , Marchetto reveals that her treatment would have cost her $200,000 without health insurance
which she did not have when she was diagnosedbut fortunately her marriage gave her access to
coverage under her new husband's policy. She also continued to work during the months of her
treatment, even standing in the weekly line-up to Mankoff's office where the New Yorker cartoonists wait
to submit their newest work for publication approval. Marchetto's career prospects brightened
considerably when Cancer Vixen was published: She was declared disease-free by her doctors, and
Working Title Films optioned the rights to her book, with Academy-Award winner Cate Blanchett slated to
star in the 2008 screen adaptation.
In February of 2007, Publishers Weekly announced that Marchetto was under contract for another graphic
novel, this one about a New York City woman whose adept networking skills suddenly make her unable to
make any sort of decision on her own at all. The storyline was undoubtedly borrowed from Marchetto's
own experience with her illness, when a chorus of advice-givers assaulted her daily. "It started at the very
beginning, on that very day," she told Gordon, the Mail on Sunday interviewer, "and it was so hard
because you have everyone telling you that you should do different things at a point when you really don't
know what the best thing to do is."