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Drug

Cisplatin

Dose-Limiting
Toxicity
Nephrotoxicity

Carboplatin

Myelosuppression

Oxaliplatin

Myelosuppression,
diarrhea

Other Toxicities
n/v, peripheral
neuropathy,
ototoxicity,
peripheral
neuropathy,
electrolyte wasting
**Radiosensizer
n/v, peripheral
neuropathy,
ototoxicity
n/v, peripheral
neuropathy,
pharyngolaryngeal
dysethesia

Emetogenic
Potential
High (>50mg/m2)
Moderate
(<50mg/m2)

Moderate
Moderate

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