ELECTRO-STIMULATION DEVICES FOR INFECTION TREATMENTS AND WOUND HEALING

SIS Manufacturing Ltd, New Zealand, had developed a range of silver iontophoresis stimulator (SIS)
devices for alternative treatments of bacterial and viral infections, and for bioelectric wound healing
stimulation.

The range consists of battery powered, non-invasive and portable electro-stimulator devices that can be
applied by the general population and by healthcare professionals without any electro-medical or
medical experience or expertise. The devices are coupled with the worlds first generally available SIS
silver-nylon cloth electrode that has been custom designed and manufactured for the SIS electrostimulators.
ELECTROMEDICAL INFECTION TREATMENT DEVICES
Alternative treatment of Helicobacter pylori (H pylori)

Successful, pure electromedical, no antibiotics results have been achieved for Helicobacter
pylori (H. pylori) infections. Initial infections and treatment outcomes were diagnosed and
monitored with standard laboratory C-14 urea breath test and histology techniques.
Conventionally, H. pylori is treated with a first line triple or quadruple drug combination
including two or three antibiotics, sometimes needing repeat treatment and often accompanied
by severe side-effects. Chronic H Pylori infection can cause ulcers in the lining of the stomach
and upper intestine, and can eventually lead to stomach cancer. It is estimated that over half of
the adult population has this bacterium in their bodies.
Our medical technology advance presents a new and alternative, non-invasive and drug-free
approach to the treatment of bacterial and viral infections.

BIOELECTRIC WOUND HEALING DEVICE

Wound healing care is a major modern medical intervention in most countries. Chronic, non-healing
trauma or disease related wounds cost national annual healthcare budgets tens of billions of dollars.
The SIS machine W100 is the world's first real-time, self-adaptive electro-stimulator. Our advanced
electromedical wound healing device operates on three new methods of wound stimulation:

The SIS machine W100 and SIS silver-nylon electrode integrated system produces the most
active, continuous delivery presently available of electrically generated silver ions to an infected
wound and for prevention of wound infection.
The SIS machine W100 is the first commercial device that provides real-time monitoring,
supplementation or replacement of the major bioelectric wound healing event. The monitoring
and stimulation of the endogenous wound-generated electric field, that is a major controller of
surface wound healing, has previously only been performed within a research setting.
The SIS machine W100 version completely and accurately fulfills the specifications of the
patented methods of electro-stimulation for promoting in situ tissue regeneration as disclosed
in USA patents 5814094A and US 5814094A.

The SIS W100 wound healing device and SIS electrode system can be applied without directly contacting
the wound. This advance over existing silver-impregnated wound dressings, avoids the disadvantage of
mechanical interference by the wound dressing with the critical event of granulation tissue formation.
For product details visit: siselectromed.com and for research information visit sismachine.com
SIS Manufacturing Ltd, New Zealand
All SIS Manufacturing Ltd equipment and technology is patent pending and trademarked. Address for all
commercial and sales correspondence: 4/20 Clarendon Street, Frankston, VIC 3199 Australia. Phone:
+64 3 669 0509 within Australia: 03 9781 1889 Fax: +61 3 9781 1884 All non-sales enquiries:
contact@sismachine.com Sales enquiries: sales@sismachine.com