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Disease
Tuberculosis
Primary Complex is
less than 3 years old
- any child who does
not return to normal
health after measles or
whooping cough.
Most hazardous
period: first 6-12
months after
infection
Highest in risk of
developing: under 3
years old
Causative Agent
Mode of
Transmission
Clinical Manifestation
Reservoir
Diagnostic Exam
Treatment
Mycobacterium
Droplet Infection
Man
( inhalation of bacilli
from patient who
coughs and sneeze)
Sputum Exam
3 sample are taken
with 24 hrs:
DOTS
Tuberculosis
General weakness
Loss of weight, cough and
wheeze which does not
respond to antibiotic
therapy.
Fever and night sweat
Abdominal swelling with a
hard painless mass and free
fluid
Hemoptysis and chest pain
Painful firm or soft
swelling in a group of
superficial lymph nodes.
Note:
Degree of
Communicability
Depends upon:
- num.of bacilli
- virulence of bacilli
- environmental
And
Diseased Cattle
(Bovine TB)
- early morning
specimen
- spot sample
- patient is required
to take the Ant-Tb
drugs in the
presence of a health
care provider to
ensure compliance
to treatment
regimen
(2nd visit)
Note: at least 2
sample are
positive
Nursing Implication
Rifampicin: taken
befor meals, causes red
urine urine
Isoniazide: causes
peripheral neuritis,
given with Vit.B6
Pyrazinamide: cause
hyperurucemia
Anti-TB drugs:
Ethambutol: causes
conditions
thrive
(RIPES)
Chest Xray
Mantoux Test
- .1 cc injection of
PDD and 48-72
hours reading
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
Streptomycin
* 10 mm +
5 mm + (HIV pt.)
Note: After 2-4 weeks
of treatment, patient is
no longer contagious
Strategies:
Targets:
1. Cure at least 85% of the sputum smear- positive TB patient discovered.
2. Detect at least 70% of the estimated new sputum smear-positive TB cases.
Objective D:
Strategies:
Enhance managerial capability of all NTP program managers at all levels
Establish an efficient data management system for both public and private sectors.
Implement a standardized recording and reporting system.
Conduct regular monitoring and evaluation at all levels.
Advocate for political support through effective local governance
KEY POLICIES
Case Finding
1.
2.
All TB symptomatic identified shall undergo DSSM for diagnosis before start of
treatment
Note: Only contraindication for sputum collection is hemoptysis
3.
After three sputum specimen yielding negative result X-ray and culture are
necessary
Note: Diagnosis based on Xray shall be made by the TB DiagnosticCommittee.
4.
Objective B:
Enhance the health-seeking behavior on TB by communities, especially the TB
symptomatics
Strategies:
Develop effective, appropriate and culturally-responsive IEC/communication materials.
Organize barangay advocacy groups
Objective C:
Category
Type of TB Patient
Treatment
Regimen
Intensive
Phase
Continuation
Phase
Total
Period
2 RIPE
4 RI
6 mos.
5 RIE
8 mos.
4 RI
Anti-TB drugs:
(RIPES)
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
Streptomycin
Fixed-Dose Combination ( FDCs) two or more first line anti-TB drugs are combined in
one tablet. There are 2,3, or 4 drug fixed dose combinations.
Single Drug Formulation (SDF) each drug is prepared individually. Isoniazid,
Pyrazinamide and Ethambuto are in tablet form while Rifampicin is in capsule form and
streptomycin is injectable.
II
III
IV
2 RIPES /1
RIPE
2 RIP
mos.
Refer to
Specialized
facility
or DOTS
Plus Center
refer
Provincial
NTP
to City
Coordinator
Body
Weight
Intensive
Phase
Continuation
Phase
FDC-B
( RI )
400 mg
The number of tablets of FDCs per patient will depend on the body weight.
First Two (2)
Months
3rd Month
Streptomycin
(RIPE)
Body Weight (kg)
FDC-A
(RIPE)
Intensive Phase
Continuation Phase
( 2 months )
( 4 months )
FDC-A ( RIPE)
FDC-B (RI)
30 - 37
38 54
55 70
More than 70
30 37
0.75 g
38 54
0.75 g
55 70
0.75 g
More
than 70
0.75 g
Intensive Phase
Continuation Phase
( 2 months )
( 4 months )
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
Anti-TB Drugs
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
Streptomycin
Anti-TB Drugs
No. of Tablets /
Intensive
( 5 months )
First 2 months
3rd months
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
2
1 vial
per day
Continuation Phase
(3months )
Streptomycin
5 Elements of D.O.T.S
Sustained political commitment
Access to quality-assured sputum microscopy
Standardized short-course chemotherapy for all cases of TB
Uninterrupted supply of essential drugs
Recording and reporting system enabling outcome assessment of all patients and
assessment of overall program performance.
Management
Prevention
A child shall be clinically diagnosed or confirmed of having TB if he has any three (3) of the
following condition:
positive history of exposure to an adult/ adolescent TB case
presence of sign and symptoms suggestive of TB
positive Mantoux Test
abnormal chest radiograph suggestive of TB
A child to have signs and symptoms of TB with either known or unknown exposure
shall be referred for Mantoux test.
For children with known contact but with negative Mantoux and those unknown contact
but with positive Mantoux shall be referred for chest x-ray examination.
For a negative x-ray report, Mantoux test shall be repeated after 3 months.
Chemoprophylaxis of Isoniazid for 3 months shall be given to children less than 5 years
old with negative chest x-ray after which Mantoux test shall be repeated
Treatment
D.O.T.S will still be followed just like in adult
Short course regimen:
- at least 3 anti-TB drugs for 2 months ( intensive phase )
- 2 anti-TB drugs for 4 months ( continuation phase )
* For Extra Pulmonary TB Cases:
- 4 anti-TB drugs for 2 months ( intensive phase )
- 2 anti-TB drugs for 10 months ( continuation phase )
Domiciliary treatment shall be the preferred mode of care
No treatment shall be initiated unless the patient and health worker has agreed upon a
caseholding mechanism for treatment compliance.
Treatment Regimen
Continuation Phase
A. Pulmonary TB
Drugs
Rifampicin
Isoniazid
Daily Dose (mg/kg per body weight )
Duration
2 months
10 months
Intensive Phase
Rifampicin
Isoniazid
Pyrazinamide
4 months
1.
2.
3.
4.
5.
6.
B. Extra Pulmonary TB
Drugs
Duration
Intensive Phase
Rifampicin
Isoniazid
Pyrazinamide
Plus
Ethambutol
OR
Streptomycin
2 months
Causative Agent
Mode of
Transmission
Clinical Manifestation
Reservoir
Diagnostic
Treatment
Nursing Implication
Exam
Diphteria it is an
acute pharyngitis, acute
nasopharyngitis
Corynebacterium
Respiratory
Droplets
diphtheriae
Nasal
Man
Schicks Test
Pharyngeal
Antibiotics
Pen G Potassium
Erythromycin
Moloney Test
Bullneck
appearance because of
the enlarge cervical
lymph nodes.
- for hypersensitivity to
Diptheria toxin
Laryngeal
Pertussis
- 100 days cough
- Whooping cough
- tuspirina
Bordetella Pertussis
Airborne droplet
Primarily by direct
contact with he
discharge from
respiratory mucous
membranes of
infected person
sore throat
hoarseness
brassy metallic cough
At first, the infected
child may have a
common cold with
runny nose, sneezing
and mild cough
Intermittent episode
of paroxysmal cough
followed by a whoop
ending vomiting
Bordet-Gengou
Agar Plate
Erythromycin
Ampicillin
Man
Neonatal Tetanus
Clostridium Tetani
Unhygienic cutting
of umbilical cord
Improper handling
of cord stump esp.
when treated with
contaminated
substance
Blood Culture
CSF analysis
In OLDER CHILDREN,
the following may be
observed:
Trismus lockjaw
Opisthotonus
arching of the neck
and back
Ridus Sardonicus
sardonic smile
Penicillin
Erythromycin
Tetracycline
- administered within
4 hours of injury
Soil
Intestinal
canal of
animal
Man
Prevention
Aseptic handling of
the neonatal
umbilical cord
Tetanus Toxiod
immunization for
mothers
Active immunization
of DPT
Poliomyelitis
Infantile Paralysis
Fecal-oral route
Throat swab
Man
Stool exam
Non-paralytic slight
involvement of the CNS
Lumbar exam
Contact with
infected person
Strict Isolation
Hot moist compress
to relieve spasm
Poker spine or
stiffness of the spinal
column
Use protective
devices:
- handroll to prevent
claw hand
Pandys test
- for CSF analysis
Spasms of the
hamstring
With paresis
- trochanter roll, to
prevent outer rotation
of femur
- footboard
Paralytic severe
involvement of CNS
Hepatitis B
- it is liver infection
caused by the B type of
hep.virus.
Prodromal/pre-icteric
Hepa B Virus
3 Ps
Person to person
Liver Function
Test
Man
Paramyxo Virus
Droplet
Increase CHO
Moderate fat
Low CHON
Observed universal
precaution
Parenteral
Placental
Measles
Symptoms of URTI
Weight loss
Anorexia
RUQ pain
Malaise
Icteric
Jaundice
Acholic stool
bile-colored urine
3 Cs
Conjunctivitis
Coryza
Cough
Kopliks spot bluish
gray spot on the buccal
mucosa.
Generalized blotch rash
Man
Observe respiratory
isolation
Should kept out of
school for at least 4
days after rash
appear
For Photophobic,
darkened room,
sunglasses
Disease
Causative Agent
Mode of Transmission
Vibrio cholera
Vibrio coma
Ogawa and Inaba
bacteria
Fecal-oral route
5 Fs
Amoebic
Dysentery
Entamoeba histolytica
Protozoan (slippershaped
body)
Fecal-oral route
Shigellosis
Shigella bacillus
Sh-dysenterae most
infectious
Sh-flesneri common
in
the Philippines
Sh-connei
Sh-boydii
Fecal-oral route
Salmonella typhosa
(plural, typhi)
Fecal-oral route
5 Fs
Cholera
Other names:
El tor
Other names:
Bacillary
dysentery
Typhoid fever
Incubation Period:
Few hours to 5 days;
Usually 3 days
Pathognomonic Sign
Prevention
Diagnostic Test:
Stool culture
Treatment:
Oral rehydration solution (ORESOL)
IVF
Drug-of-Choice: tetracycline (use straw; can
cause staining of teeth).
Oral tetracycline should be
administered with meals or after milk.
Abdominal
cramping
Bloody mucoid stool
Tenesmus - feeling
of
incomplete defecation
Metronidazole (Flagyl)
* Avoid alcohol because of its Antabuse effect
can cause vomiting
Proper handwashing
Proper food and water
sanitation
Abdominal
cramping
Bloody mucoid stool
Tenesmus - feeling
of incomplete
defecation
Drug-of-Choice: Co-trimoxazole
Proper handwashing
Proper food and water
sanitation
Fly control
Diagnostic Test:
Proper handwashing
Proper food and water
sanitation
Immunization of Chole-vac
Incubation Period:
1 day, usually less
than 4 days
Incubation Period:
Usual range 1 to 3
weeks, average 2
weeks
Proper handwashing
Proper food and water
sanitation
Hepatitis A
Hepatitis A Virus
Other names:
Hepatitis /
Epidemic
Hepatitis /
Catarrhal Jaundice
Paralytic
Shellfish
Poisoning (PSP I
Red tide
poisoning)
Fecal-oral route
5 Fs
Incubation Period:
15-50 days,
depending on dose,
average 20-30 days
Dinoflagellates
Phytoplankton
Ingestion of raw of
inadequately cooked
seafood usually
bivalve mollusks
during red tide
season
Incubation Period:
30 minutes to
several hours after
ingestion
Fever
Anorexia (early sign)
Headache
Jaundice (late sign)
Clay-colored stool
Lymphadenopathy
Numbness of face
especially around the
mouth
Vomiting and
dizziness
Headache
Tingling
sensation/paresthesia
and
eventful paralysis of
hands
Floating sensation
and
weakness
Rapid pulse
Dysphonia
Dysphagia
Total muscle
paralysis
leading to respiratory
arrest and death
Treatment:
1. No definite treatment
2. Induce vomiting
3. Drink pure coconut milk weakens the
toxic effect
4. Sodium bicarbonate solution (25 grams in
glass of water)
Advised only in the early stage of illness
because paralysis can lead to aspiration
NOTE: Persons who survived the first 12 hours
after
ingestion have a greater chance of survival.
Proper handwashing
Proper food and water
sanitation
Proper disposal of urine
and feces
Separate and proper
cleaning of articles used by
patient
Causative Agent
Human (alpha) herpes
virus 3 (varicella-zoster
virus), a member of the
Herpesvirus group
Period of
Communicability:
From as early as 1 to 2
days before the rashes
appear until the lesions
have crusted.
Mode of Transmission
Droplet spread
Direct contact
Indirect through articles
freshly soiled by
discharges of infected
persons
Incubation Period:
2-3 weeks, commonly
13 to 17 days
Pathognomonic Sign
Vesiculo-pustular
rashes
Centrifugal
appearance of
rashes rashes which
begin on the trunk and
spread peripherally
and more abundant on
covered
body parts
Pruritus
Prevention
Nursing Diagnoses:
Disturbance in body image
Impairment of skin integrity
German
Measles
Other Names:
Rubella
Three-day
Measles
Herpes Zoster
Other names:
Shingles
Cold sores
Rubella virus or
RNAcontaining
Togavirus
(Pseudoparamyxovirus)
Droplet
Incubation Period:
Three (3) days
German measles is
teratogenic infection,
can cause congenital
heart disease and
congenital
cataract.
Herpes zoster virus
(dormant varicella
zoster
virus)
Droplet
Direct contact from
secretion
Forscheimer spots
red pinpoint patches
on the oral cavity
Maculopapular rashes
Headache
Low-grade fever
Sore throat
Enlargement of
posterior cervical and
postauricular
Diagnostic Test:
Rubella Titer (Normal value is 1:10); below 1:10
indicates susceptibility to Rubella.
Painful vesiculopustular
lesions on limited
portion of the body
(trunk and
shoulder)
Low-grade fever
Avoidance of mode of
transmission
Mumps
Other name:
Epidemic Parotitis
Mumps virus, a
member
of family
Paramyxoviridae
Direct contact
Source of infection:
Secretions of mouth and
nose
Incubation Period:
12 to 26 days, usually
18 days
Painful swelling in
front of the ear, angle
of the jaws and down
the neck
Fever
Malaise
Loss of appetite
MMR vaccine
Isolate mumps cases
Swelling of one or
both testicles (orchitis)
in some boys
Influenza
Other name:
La Grippe
Influenza virus
A most common
B less severe
C rare
Period of
Communicability:
Probably limited to 3
days from clinical onset
Direct contact
wesDroplet infection or by
articles freshly soiled
with nasopharyngeal
discharges
Airborne
Incubation Period:
Short, usually 24 72
hours
Sudden onset
Fever with chills
Headache
Myalgia / arthralgia
Immunization:
Flujob/Flushot effective
for 6 months to 1 year
Causative Agent
Bacteria:
Pneumococcus,
streptococcus
pneumoniae,
staphylococcus aureus,
Klebsiella pneumonia
(Friedlanders bacilli)
Mode of Transmission
Droplet
Incubation Period:
2 3 days
Virus:
Haemophilus
influenzae
Fungi: Pneumonocystis
carinii pneumonia
Streptococcal
sore throat
Other name:
Pharyngitis
Tonsillitis
Other diseases:
Scarlet fever
St. Anthony fire
Puerperal sepsis
Imoetigo
Acute
glomerulonephritis
Rheumatic Heart
Disease
Droplet
Complication:
Rheumatic Heart
Disease
Pathognomonic Sign
Rusty sputum
Fever and chills
Chest pain
Chest indrawing
Rhinitis/common cold
Productive cough
Fast respiration
Vomiting at times
Convulsions may occur
Flushed face
Dilated pupils
Highly colored urine
with reduced chlorides
and increased urates
Diagnosis:
Based on signs and symptoms
Dull percussion on affected lung
Sputum examination confirmatory
Chest x-ray
Sudden onset
High grade fever with
chills
Enlarged and tender
cervical lymph nodes
Inflamed tonsils with
mucopurulent exudates
Headache
Dysphagia
Diagnosis:
Throat swab and culture
Prevention
Avoid mode of
transmission
Build resistance
Turn to sides
Proper care of influenza
cases
Management:
Bedrest
Adequate salt, fluid, calorie, and vitamin intake
Tepid sponge bath for fever
Frequent turning from side to side
Antibiotics based on CARI of the DOH
Oxygen inhalation
Suctioning
Expectorants / mucolytics
Bronchodilators
Oral/IV fluids
CPT
Treatment: erythromycin
Care:
Bed rest
Oral hygiene with oral antiseptic or with saline
gargle (1 glass of warm water + 1 tsp rock salt)
Ice collar
Avoid mode of
transmission
Meningitis
Other name:
Cerebrospinal
fever
Meningococcus
Neisseria meningitides
Direct (Droplet)
Incubation Period:
2 - 10 days
A. Sudden Onset
- high fever
accompanied
by chills
- sore throat, headache,
prostration (collapse)
Diagnostic Test:
Lumbar puncture or Lumbar tap - reveals CSF
WBC and protein, low glucose; contraindicated
for increased ICP for danger of cranial
herniation
Hemoculture to rule out meningococcemia
Treatment:
Osmotic diuretic (Mannitol) to reduce ICP and
relieve cerebral edema; Alert: fastdrip to prevent
crystallization
Anti-inflammatory (Dexamethasone) to
relieve
cerebral edema
Antimicrobial (Penicillin)
Anticonvulsany (Diazepam / Valium)
C. Symptoms of
menigeal
irritation
- nuchal rigidity (stiff
neck) earliest sign
- Kernigs sign when
knees are flexed, it
cannot
be extended
- Brudzinski signs
pain on neck flexion
withautomatoc flexion
of the knees
- convulsion
- poker soine (poker
face /
flat affect)
- Increased ICP
(Cushings triad:
hypertension,
bradycardia,
bradypnea)
and widening pulse
pressure
Complications:
Hydrocephalus
Deafness (Refer the child for audiology testing)
and mutism
Blindness
Respiratory Isolation
VECTOR-BORNE DISEASES
Disease
Malaria
Causative Agent
Plasmodium Parasites:
Vivax
Falciparum (most fatal;
most common in the
Philippines)
Ovale
Malariae
Mode of Transmission
Bite of infected
anopheles mosquito
Night time biting
High-flying
Rural areas
Clear running water
Pathognomonic Sign
Cold Stage: severe,
recurrent chills (30
minutes to 2 hours)
Hot Stage: fever (4-6
hours)
Wet Stage: Profuse
sweating
Episodes of chills,
fevers, and profuse
sweating are
associated with rupture
of the red blood cells.
- intermittent chills
and
sweating
- anemia / pallor
- tea-colored urine
- malaise
- hepatomegaly
- splenomegaly
- abdominal pain and
enlargement
- easy fatigability
Prevention
*CLEAN Technique
*Insecticide treatment of
mosquito net
*House Spraying (night
time fumigation)
*On Stream Seeding
construction of bio-ponds
for fish propagation (2-4
fishes/m2 for immediate
impact; 200-400/ha. for a
delayed effect)
*On Stream Clearing
cutting of vegetation
overhanging along stream
banks
*Avoid outdoor night
activities (9pm 3am)
*Wearing of clothing that
covers arms and legs in the
evening
*Use mosquito repellents
*Zooprophylaxis typing
of domestic animals like
the carabao, cow, etc near
human dwellings to
deviate mosquito bites
from man to these animals
Intensive IEC campaign
NURSING CARE:
1. TSB (Hot Stage)
2. Keep patent warm
(Cold Stage)
3. Change wet clothing
(Wet Stage)
4. Encourage fluid intake
5. Avoid drafts
Filariasis
Other names:
Elephantiasis
Endemic in 45 out
of 78 provinces
Highest
prevalence rates:
Regions 5, 8, 11
and CARAGA
Shistosomiasis
Other Names:
Snail Fever
Bilharziasis
Endemic in 10
regions and 24
provinces
High prevalence:
Regions 5, 8, 11
Dengue
Hemorrhagic
Fever
Other names:
H-fever
Wuchereria bancrofti
Brugia malayi
Brugia timori
nematode parasites
Asymptomatic Stage:
Presence of
microfilariae
in the blood but no
clinical signs and
symptoms of disease
Acute Stage:
Lymphadenitis
Lymphangitis
Affectation of male
Genitalia.
Schistosoma mansoni
S. haematobium
S. japonicum (endemic
in the Philippines)
Dengue virus 1, 2, 3,
and 4 and Chikungunya
virus
Types 1 and 2 are
common in the
Philippines
Bite of infected
mosquito (Aedes
Aegypti) - characterized
by black and white
stripes
Daytime biting
Low flying
Stagnant clear water
Urban
Diagnosis
Physical examination, history taking,
observation of major and minor signs and
symptoms
CLEAN Technique
Use of mosquito repellents
Anytime fumigation
Wear a long sleeves, pants
and socks
Laboratory examinations
Nocturnal Blood Examination (NBE) blood
are taken from the patient at his residence or in
hospital after 8:00 pm
Immunochromatographic Test (ICT) rapid
assessment method; an antigen test that can be
done at daytime
Treatment:
Drug-of-Choice: Diethylcarbamazine Citrate
(DEC) or Hetrazan
Diarrhea
Bloody stools (on and
off dysentery)
Enlargement of
abdomen
Splenomegaly
Hepatomegaly
Anemia / pallor
weakness
Diagnostic Test:
COPT or cercum ova precipitin test (stool
exam)
Classification (WHO):
Diagnostic Test:
Torniquet test (Rumpel Leads Test / capillary
fragility test) PRESUMPTIVE; positive when
20 or more oetechiae per 2.5 cm square or 1
inch square are observed
Platelet count CONFIRMATORY; (Normal
is
150 - 400 x 103 / mL)
Grade I:
a. flu-like symptoms
b. Hermans sign
c. (+) tourniquet sign
Treatment:
Drug-of-Choice: PRAZIQUANTEL
(Biltracide)
Oxamniquine for S. mansoni
Metrifonate for S. haematobium
*Death is often due to hepatic complication
Period of
communicability:
Unknown. Presumed to
be on the 1st week of
illness up to when the
virus is still present in
the
blood
Occurrence is sporadic
throughout the year
Epidemic usually occur
during the rainy seasons
(June to November)
Peak months:
September
and October
Incubation Period:
Uncertain. Probably 6
days to 1 week
Manifestations:
First 4 days:
Febrile/Invasive Stage
- starts abruptly as fever
- abdominal pain
- headache
- vomiting
- conjunctival infection
-epistaxis
4th 7th days:
Toxic/Hemorrhagic
Stage
- decrease in
temperature
- severe abdominal pain
- GIT bleeding
- unstable BP (narrowed
pulse pressure)
- shock
- death may occur
7th 10th days:
Recovery/Convalescent
Stage
- appetite regained
- BP stable
Grade II:
a. manifestations of
Grade
I plus spontaneous
bleeding
b. e.g. petechiae,
ecchymosis purpura,
gum
bleeding,
hematemesis,
melena
Grade III:
a. manifestations of
Grade
II plus beginning of
circulatory failure
b. hypotension,
tachycardia, tachypnea
Grade IV:
a. manifestations of
Grade
III plus shock (Dengue
Shock Syndome)
Treatment:
Supportive and symptomatic
Paracetamol for fever
Analgesic for pain
Rapid replacement of body fluids most
important
treatment
ORESOL
Blood tansfusion
Diet: low-fat, low-fiber, non-irritating,
noncarbonated.
Noodle soup may be given. ADCF
(Avoid Dark-Colored Foods)
ALERT! No Aspirin
Eliminate vector
Avoid too many hanging
clothes inside the house
Residual spraying with
insecticide
Daytime fumigation
Use of mosquito repellants
Wear long sleeves, pants,
and socks
For the control of H-fever,
knowledge of the natural
history of the disease is
important.
Environmental control is
the most appropriate
primary prevention
approach and control of
Hfever.
Rabies
Other Names:
Lyssa
Hydrophobia
Le Rage
Causative Agent
Leptospira interrogans
bacterial spirochete
RAT is the main host.
Although pig, cattle,
rabbits, hare, skunk,
and other wild animals
can also serve as
reservoir
Mode of Transmission
Through contact of the
skin, especially open
wounds with water,
moist soil or vegetation
infected with urine of
the infected host
Incubation Period:
7-19 days, average of
10 days
Occupational disease
affecting veterinarians,
miners, farmers, sewer
workers, abattoir
workers,
etc
Pathognomonic Sign
Leptospiremic Phase
- leptospires are present
in blood and CSF
- onset of symptoms is
abrupt
- fever
- headache
- myalgia
- nausea
- vomiting
- cough
- chest pain
Immune Phase
- correlates with the
appearance of circulating
IgM
Rhabdovirus of the
genus
lyssavirus
Degeneration and
necrosis
of brain formation of
negri bodies
Source of infection:
saliva of infected
animal or human
Incubation period:
2 8 weeks, can be
years depending on
severity of wounds, site
of wound as distance
from brain, amount of
virus introduced, and
protection provided by
clothing
Sense of apprehension
Headache
Fever
Sensory change near site
of animal bite
Spasms of muscles of
deglutition on attempts to
swallow
Fear of
water/hydrophobia
Paralysis
Delirium
Convulsions
FATAL once signs and
symptoms appear
Diagnosis:
history of bite of animal
culture of brain of rabid animal
demonstration of negri bodies
Management:
*Wash wound with soap immediately.
Antiseptics
e.g. povidone iodine or alcohol may be applied
*Antibiotics and anti-tetanus immunization
*Post exposure treatment: local wound
treatment, active immunization (vaccination) and
passive immunization (administration of rabies
immunoglobulin)
*Consult a veterinarian or trained personnel to
observe the pet for 14 days
*Without medical intervention, the rabies victim
would usually last only for 2 to 6 days. Death is
often due to respiratory paralysis.
Prevention
Protective clothing,
boots and gloves
Eradication of rats
Segregation of domestic
animals
Awareness and early
diagnosis
Improved education of
people
Avoid wading or
swimming in water
contaminated with urine
of infected animals.
Concurrent disinfection
of articles soiled with
urine.
National Rabies
Prevention and Control
Program
Goal: Human rabies is
liminated in the
Philippines and the
country is declared
rabiesfree
Disease
Leprosy
Other names:
Hansenosis
Hansens disease
-an ancient
disease and is a
leading cause of
permanent
physical disability
among the
communicable
diseases
Causative Agent
Mycobacterium leprae
Mode of Transmission
Airborne-droplet
Prolonged skin-toskin
contact
Pathognomonic Sign
Early signs:
Change in skin color
either
reddish or white
Loss of sensation on
the skin
lesion
Loss of sweating and
hair growth
Thickened and painful
nerves
Muscle weakness or
paralysis or
extremities
Pin and redness of the
eyes
Nasal obstruction or
bleeding
Ulcers that do not heal
Late Signs:
Madarosis
Loss of eyebrows
Inability to close
eyelids
(lagophthalmos)
Clawing of fingers and
toes
Contractures
Chronic ulcers
Sinking of the
nosebridge
Enlargement of the
breast
(gynecomastia)
Prevention
Avoid prolonged skin-to skin
contact
BCG vaccination
practical and effective
preventive measure
against leprosy
Good personal hygiene
Adequate nutrition
Health education
Major activity of leprosy
control program:
casefinding and treatment
with effective drugs
Prevent deformities by
self-care, exercise, and
physical therapy.
Treatment:
Ambulatory chemotherapy through use of MDT
Domiciliary treatment as embodied in RA 4073
which advocates home treatment
MDT Facts:
It reduces communicability period
of leprosy in 4-6 weeks time.
It prevents development of
resistance to drugs.
It shortens the duration of
treatment.
Anthrax
Bacillus anthracis
Other names:
Malignant pustule
Malignant edema
Woolsorter
disease
Ragpicker disease
Charbon
Incubation period:
few hours to 7 days
most cases occur within
48 hours of exposure
3. Scabies
Sarcoptes scabiei
- An itch mite
parasite
Contact with
a. tissues of animals
(cattle, sheep, goats,
horses, pigs, etc.)
dying of the disease
b. biting flies that
had partially fed on such
animals
c. contaminated hair,
wool, hides or products
made from them e.g.
drums and brushes
d. soil associated
with infected animals or
contaminated bone
meal used in
gardening
Treatment: Penicillin
Proper handwahing
Immunize with cell-free
vaccine prepared from
culture filtrate containing
the protection antigen
Control dust and proper
ventilation
Pulmonary form
contracted from
inhalation of B.
anthracis spores
- at onset, resembles
common URTI
- after 3-5 days,
symptoms become
acute, with fever,
shock,
and death
Gastrointestinal
anthrax
contracted from
ingestion of meat from
infected animal
- violent gastroenteritis
- vomiting
- bloody stools
Itching
When secondarily
infected:
Skin feels hot and
burning
When large and
severe: fever,
headache, and malaise
Diagnosis:
Appearance of the lesion
Intense itching
Finding of causative mite
Treatment: (limited entirely to the skin)
Examine the whole family before undertaking
treatment
Benzyl benzoate emulsion (Burroughs,
Welcome)
cleaner to use and has more rapid effect
Kwell ointment
Personal hygiene
Avoid playing with dogs
Laundry all clothes and
iron
Maintain the house clean
Environmental sanitation
Eat the right kind of food
Regular changing of clean
clothing, beddings and
towels
Disease
Syphilis
Other names:
Sy
Bad Blood
The pox
Lues venereal
Morbus gallicus
Gonorrhea
Other names:
GC, Clap, Drip,
Stain, Gleet,
Flores Blancas
Causative Agent
Treponema pallidum
(a spirochete)
Incubation Period:
10 to 90 days (3
months);
average of 21 days
Neiserria gonorrheae
Mode of Transmission
Direct contact
Transplacental (after
16th week AOG)
Through blood
transfusion
Indirect contact with
Contaminated articles
Direct contact
genitals, anus,
mouth
Incubation Period:
2 10 days
Pathognomonic Sign
Primary stage (4-6
weeks): painless
chancre at site of entry
of germ
with serous exudates
Tertiary stage (one to
35 years) : Gumma,
syphilitic endocarditis
and meningitis
Primary and secondary
sores will go even
without treatment but
the germs continue
to spread throughout
the body.
Latent syphilis may
continue 5 to 20+
years with NO
symptoms, but the
person is NO longer
infectious to other
people.
A pregnant
mother can transmit
the disease to her
unborn child
(congenital syphilis).
Thick purulent
yellowish discharge
Burning sensation
upon
urination / dysuria
Prevention
Abstinence
Be faithful
Condom
Treatment:
Drug of Choice: Penicillin (Tetracycline if
resistant
to Penicillin)
Diagnostic test:
Culture of urethral and cervical smear
Gram staining
Treatment:
Drug of Choice: Penicillin
Abstinence, Be faithful
Condom
Prevention of gonococcal
ophthalmia is done through
the prophylactic use of
ophthalmic preparations
with erythromycin or
tetracycline
Trichomoniasis
Trichomonas vaginalis
Other names:
Vaginitis
Trich
Direct contact
Incubation Period:
4 20 days; average
of 7 days
Females:
white or greenishyellow odorous
discharge vaginal
itching and soreness
painful urination
Diagnostic Test:
Culture
Treatment:
Drug of Choice: Metronidazole (Flagyl)
Abstinence
Be faithful
Condom
Personal Hygiene
Males:
Slight itching of penis
Painful urination
Clear discharge from
penis
Chlamydia
Chlamydia trachomatis
(a rickettsia)
Direct contact
Incubation Period:
2 to 3 weeks for
males; usually no
symptoms for
females
Candidiasis
Other names:
Moniliasis
Candidosis
Candida albicans
Direct contact
Females:
Asymptomatic
Dyspareunia
Fishy vaginal
discharge
Diagnostic Test:
Culture
Abstinence
Be faithful
Condom
Treatment:
Drug of Choice: Tetracycline
Males:
Burning sensation
during
urination
Burning and itching of
urethral opening
(urethritis)
White, cheese-like
vaginal
discharges
Curd like secretions
Diagnostic Test:
Culture
Gram staining
Treatment:
Nystatin for oral thrush
Cotrimazole, fluconazole for mucous
membrane and vaginal infection
Fluconazole or amphotericin for systemic
infection
Abstinence
Be faithful
Condom
Acquired
immune
deficiency
syndrome (AIDS)
Retrovirus
(Human T-cell
lymphotrophic virus 3
or HTLV 3)
Attacks the T4 cells:
Thelper
cells; Tlymphocytes,
and CD4
lymphocytes
The major route of HIV
transmission to
adolescent
is SEXUAL
TRANSMISSION.
French kissing brings
low
risk of HIV
transmission.
Window Phase
a. initial infection
b. lasts 4 weeks to 6
months
c. not observed by
present
laboratory test (test
should
be repeated after 6
months)
Acute Primary HIV
Infection
a. short, symptomatic
period
b. flu-like symptoms
c. ideal time to
undergo
screening test (ELISA)
Asymptomatic HIV
Infection
a. with antibodies
against HIV but not
protective
b. lasts for 1-20 years
depending upon
factors
ARC (AIDS Related
Complex)
a. a group of
symptoms indicating
the disease is likely to
progress to AIDS
b. fever of unknown
origin
c. night sweats
d. chronic intermittent
diarrhea
e. lymphadenopathy
f. 10% body weight
loss
Abstinence
Be faithful
Condom
Sterilize needles, syringes,
and instruments used for
cutting operations
Proper screening of blood
donors
Rigid examination of blood
and other blood products
Avoid oral, anal contact
and swallowing of semen
Avoid promiscuous sexual
contact
Avoid sharing of
toothbrushes.
HIV/AIDS Prevention
and Control Program:
Goal: Contain the
transmission of HIV /AIDS
and other reproductive tract
infections and mitigate
their impact
LECTURE DISCUSSION
best method to use in
teaching about safe sex
Priority intervention when
caring for AIDS patient:
Use disposable gloves
when in contact with non intact
skin.
AIDS
a. manifestation of
severe
immunosuppression
b. CD4 Count:
<200/dL
c. presence of variety
of
infections at one time:
oral candidiasis
leukoplakia
AIDS dementia
complex
Acute encephalopathy
Diarrhea, hepatitis
Anorectal disease
Cytomegalovirus
Pneumonocystis
carinii
pneumonia (fungal)
TB
Kaposis sarcoma
(skin
cancer; bilateral
purplish
patches)
Herpes simplex
Pseudomonas
infection
Blindness
Deafness
Causative Agent
Meningococcemia
Neisseria meningitides
Mode of Transmission
Direct contact with
respiratory droplet from
nose and throat of
infected individuals
Incubation Period:
2 10 days
Severe Acute
Respiratory
Syndrome / SARS
Coronavirus
Earliest case:
Guangdong
Province,
China in November
2002
Prevention
Prodromal Phase:
Fever (>38 0C)
Chills
Malaise
Myalgia
Headache
Infectivity is none to
low
No specific treatment
PREVENTIVE MEASURES and CONTROL
1. Establishment of triage
2. Identification of patient
3. Isolation of suspected probable case
4. Tracing and monitoring of close contact
5. Barrier nursing technique for suspected
and probable case
Control in birds:
1. Rapid destruction (culling or stamping out of
all infected or exposed birds) proper disposal of
carcasses and quarantining and rigorous
disinfection of farms
2. Restriction of movement of live poultry
In humans:
1. Influenza vaccination
2. Avoid contact with poultry animals or
migratory
birds
Isolation technique
Vaccination
Proper cooking of poultry
Drug-of-Choice: Penicillin
Universal precaution
Chemoprophylaxis with
Rifampicin to protect
exposed individual from
developing the infection
Proper hand washing
Respiratory Phase:
Within 2-7 days, dry
nonproductive cough
progressing to
respiratory
distress
Global outbreak:
March 12, 2003
First case in the
Philippines:
April 11, 2003
Bird Flu
Other Name:
Avian Flu
Pathognomonic Sign
Fever
Body weakness and
body
malaise
Cough
Sore throat
Dyspnea
Sore eyes
Influenza A
(H1N1)
Other Name:
Swine Flu
May 21, 2009
first confirmed
case in the
Philippines
June 11, 2009
The WHO raises
its Pandemic Alert
Level to Phase 6,
citing significant
transmission of the
virus.
Influenza Virus A
H1N1
This new virus was
first detected in people
in April 2009 in the
United States.
Influenza A (H1N1) is
fatal to humans
Exposure to droplets
from the cough and
sneeze of the infected
person
Influenza A (H1N1) is
not transmitted by
eating thoroughly
cooked pork.
The virus is killed by
cooking temperatures of
160 F/70 C.
Incubation Period:
7 to 10 days
- similar to the
symptoms
of regular flu such as
Fever
Headache
Fatigue
Lack of appetite
Runny nose
Sore throat
Cough
- Vomiting or nausea
- Diarrhea
Diagnostic:
Nasopharyngeal (throat) swab
Immunofluorescent antibody testing to
distinguish influenza A and B
Treatment:
Antiviral medications may reduce the severity
and
duration of symptoms in some cases:
Oseltamivir (Tamiflu)
or zanamivir