FIRST AID IMMUNOLOGY

1. Outer cortex of lymph node contain which cells?

2. Which area of lymph node is not well developed in digeorge syndrome?
3. Lymph drainage of lateral side of dorsum of foot?
4. Lymph drainage of rectum below pectinate line?
5. T cells are found in which pulp of spleen?
6. Thymus is derived from?
7. MHC gene is located on which chromosome?
8. APC cells expresses which MHC class?
9. Grave disease is associated with why HLA subtype?
10. NK cells uses what for induction of apoptosis?
11. Antibodies are produced by which cells ?
12. Positive selection is done in which part of thymus?
13. Name APCs??
14. Costimulatory signal is given by interaction between?
15. Th1 cells inhibited by?
16. Which portion of IGM and IGg fixes complement?
17. Light chain contributes to which fraction of anticody?
18. Main antibody in secondary response to antigen?
19. Colostrum contain which antibody?
20. IgE mediates immunity against worms by activating ?
21. Mature B lymphocytes express ------ on their surfaces?
22. Most abundant antibody in blood?
23. Antibody with lowest concentration in serum?
24. Classic complement pathway mediated by which antibody?
25. Neutrophil chemotaxis done by which complement?
26. C1 esterase inhibitor def causes which disease?
27. Decay accelerating factor causes which disease?
28. antibody pentamer in serum ??
29. Name the opsonins in bacterial defense?
30. Recurrent Neisseria bacteremia is caused due to def of?
31. Which IL inhibit inflammation?
32. Name the IL that supports growth factor and differentiation of bone marrow stem
cells ?
33. IL causes fever and stimulates production of acute phase reactants?
34. Cytokine mediates septic shock ?
35. Name unique marker of NK?
36. All cells have MHC-I except?
37. Receptor for EBV on B cells ?
38. Self reactive T cells become non reactive without Costimulatory molecule ... This
phenomenon is called ??
39. IgA in Breast milk is form of which immunity ?
40. Antibody involved in type 1 HSR?
41. Cytotoxic hypersensitivity is which type of hypersensitivity?
42. In erythroblastosis fetalis which Ig is involved?

43. Hashimoto thyroiditis involves which type of hypersensitivity ?

44. Rheumatic fever is which type of HSR?
45. Anti mitochondrial antibody associated disorder?
46. Mixed connective tissue disease associated with which autoantibody?
47. Drug induced sle associated with hitch antibody?
48. T cell deficiencies produce which infections mostly?
49. In Brutton aggamaglobinemia defect is in which gene?
50. Jobs syndrome increases which immunoglobulin ?
51. Digeorge syndrome is failure to develop?
52. Sinus and lung infections are caused by which Ig deficiency?
53. SCID is due to defective?
54. Wiskott-Aldrich syndrome presentation triad is ??
55. Graft from twin or clone is called ?
56. Rejection occurs within minutes of transplantation is called ?
57. Vasculitis of graft vessels with dense interisitial lymphocytic infiltrate is feature of
which type f rejection?
58. Most common infection in transplant recipient ?
59. Target of infliximab is ?
60. Target of transtuzumab is ?
61. Drug used to prevent acute transplant rejection?
62. Serum sickness is which type of hypersensitivity ?
63. In ataxia talengectasia which gene is defective?
64. Contact dermatitis is which HSR?
65. Fibrinoid necrosis is hallmark of which HSR?
66. Live attenuated vaccine mainly induced which response?
67. Half life of passive immunity is ?
68. IL that promotes differentiation of B cells ??
69. IL that activates NK cells?
70. MAC complex is formed by?
71. IgA in circulation is in which form ?
72. Which fragment of antibody determines idiotype?
73. Foreign body is phagocytosed by?
74. MHC II expressed only on?
75. HLA B27 Associated with which disease ?
76. NK activity is enhanced by?
77. Lymph drainage of stomach ?
78. Lymph drainage os scrotum?
79. During extreme cellular immune response which area of lymph node enlarges ?
80. Most common congenital immunoglobulin deficiency?
81. Which transplant has best allograft survival rate ??
82. Most common drug induced lupus?
83. Most common cause of death in SLE?
84. Reservoir of HIV is ?
85. Amyloidosis of which organ is most serious form of organ involvement?
86. Which rest for AIDS is confirmatory?
87. Complement components are synthesized mostly in?

88. Sjogren syndrome is associated with?

89. Initial most sensitive test for SLE?
90. Patient has CRF best donor for this patient is ??
91. Master switch to nucleus for induction of inflammation?
92. IL that stimulates and activates eosinophils ?
93. Methyl dopa alters which antigen on Rbc surface?
94. Amyloid precursor protein is located on which chromosome?
95. Misfolded proteins are normally removed by ?
KEYS
1. B cells
2. Paracortex
3. Popliteal
4. Superficial inguinal
5. White pulp
6. 3 rd pharyngeal pouch
7. Chr. 6
8. MHC - II
9. B8
10. Perforins and granzyme
11. Plasma cells
12. Thymic cortex
13. Macrophage, dendritic cell, B cell
14. B7 and CD28
15. IL-10
16. Fc
17. Fab
18. IgG
19. IgA
20. Eosinophils
21. IgM and IgD
22. IgG
23. IgE
24. IgG and IgM
25. C5a
26. Hereditary angoidema
27. PNH
28. IgM
29. C3b and IgG
30. C3-C8 def
31. IL-10
32. IL-3
33. IL-6
34. TNF-alpha
35. CD56
36. Rbc

37. CD21
38. Anergy
39. Passive
40. IgE
41. Type 2
42. ? IgG
43. Typed IV
44. Type II
45. Primary biliary cirrhosis
46. Anti RNP
47. Anti histone
48. Fungal ad viral
49. Tyrosine kisane gene
50. IgE
51. 3rd and 4th pharyngeal pouches
52. Selective IgA deficiency
53. IL-2 receptor
54. Thrombocytopenia , infections and eczema
55. Syngeneic graft
56. Hyperacute rejection
57. Acute rejection
58. CMV
59. TNF-a
60. Erb-B2
61. Daclizumab
62. Type III
63. ATM gene
64. Type IV
65. TypeIII
66. Humoral
67. 3 weeks
68. IL5
69. IL12
70. C5b-9f
71. Monomer
72. Fab
73. APC
74. APC
75. Psoriasis , ankylosing spondylitis , IBD and Reiter syndrome
76. IL-12, IFN-b, IFN-a
77. Celiac
78. Sup inguinal
79. Paracortex
80. IgA
81. Corneal transplant
82. Procainamide

83. Infections
84. Dendritic cells
85. Kidney
86. Western blot
87. Hepatocyte
88. Rheumatoid arthritis
89. ANA
90. Twin
91. NFkb
92. IL-5
93. Rh antigen
94. Ch.21
95. Proteasomes

REGARDS
DR NOOR UL BASAR