Valimentas Liposomal Technology is Proven for Bioavailability and Efficacy via

University Clinical Trials!

www.Valimenta.com
info@valimenta.com
ValimentaTM Labs is proud to be a science-based company, founded by Ph.D. chemists.
We combine the newest techniques to provide the most natural and healthy products
possible.
Full report available at:
www.valimenta.com and http://www.valimenta.com/clinicalstudies/
What is a liposome?
Liposomes are tiny nano-sized bubbles with an outer shell comprised of healthy lipids
and a hollow aqueous center that can be filled with a variety of substances, such as
Vitamin C. We have long postulated that the outer layer of the liposome protects the
Vitamin C from gastric juices and liver enzymes; now, clinical studies are showing that
liposomes support the absorption of nutrition, such as Vitamin C, and has excellent
efficacy.
NUMBER 1: How much Vitamin C gets into the blood?
While high doses of regular vitamin C powder or capsules will be rejected at high rates
from your body, Liposomal Vitamin C is a fantastic alternative.
Starting in 2012, a team at the Department of Health and Exercise Science at Colorado
State University has been comparing Vitamin C concentrations in the blood after
swallowing a normal Vitamin C powder, and after ingestion of Liposomal Vitamin C,
made using our formulation and technology, in order to understand Vitamin C
bioavailability.

Figure 1 shows that, compared with

normal Vitamin C ingestion (single
dose of 4 g), ingestion of Liposomal
Vitamin C (also 4 g) leads to
appreciably greater circulating
Vitamin C concentrations. Hence,
liposomes facilitate Vitamin C
delivery to the blood.

NUMBER 2: What will Vitamin C

do once in the blood?
The next step in the study is to determine if the Vitamin C concentration is meaningful.
In this regard, an ischemia reperfusion study was performed. Ischemia describes any
tissue that has been deprived of blood and oxygen. Reperfusion occurs when the blood
and oxygen supply is returned. Unfortunately, reperfusion can cause massive oxidative
stress on your cardiovascular system, as the oxygen interacts with metabolites produced
by the oxygen-deprived tissues. Per the blue line in the figure below, oxidative stress
was reduced even during the increased oxidative stress of reperfusion.

Figure 2 illustrates that ingestion of liposomal Vitamin C quenches the oxidative stress
(reactive oxygen species) during an ischemia-reperfusion study using a blood pressure
cuff around the upper arm and inflated to very high pressures for 20-minutes.
NUMBER 3: What is the size of the liposomes using this technology?

Number of Paritcles

Another step in our study is to characterize size ranges for our formulations. Figure 3
shows that we have been making Liposomal Vitamin C with a peak particle size of 85 nm
(nanometers) and with 92% of the particles being between 60 and 172 nm. This tight
distribution is indicative of a reproducible and highly controlled manufacturing
methodology that we invented. This study was performed using dynamic light scattering
analysis of the liposomal diameter size of liposomal vitamin c.

0.

250.
500.
750.
Particle Size (Nanometers)

1000.

The no pressure, no heat, no solvent technology invented during our 15 years of research
on lipid structure that was released in 2010, can be used to make a variety of lipid
structures and make liposomes of various sizes.
To ensure the highest purity and efficacy for this formulation:
1. The liposomes are made of non-hydrogenated natural lipids from sunflower
source (soy free/non-allergen)
2. A natural manufacturing method is used that does not use heat, pressure, nor
organic solvents.
3. The formulation is alcohol free.
4. The process is run in a cGMP certified facility specifically for liposome
manufacturing.
5. The facility is common allergen free.
If you would like information on Valimenta Labs liposomal products, custom
formulations, or private labeling please contact us.
Dont hesitate to contact us,
Info@valimenta.com
www.Valimenta.com
ValimentaTM Labs