University/Academy:

Faculty/Institute:
Department:

University of Alexandria
Faculty of Science
Zoology Department
Form no. (12)

Course Specification

1- Course Data
Course Code:

Course Title:

Academic Year/Level:

MB 301

Molecular Biology (1)

3rd level

Specialization:

No. of Instructional Units:

Molecular Biology

2- Course Aim

Lecture

Practical

To acquire the knowledge and mastery of Molecular

Biology through a deep understanding of the structure and
function of living organisms at a molecular level, as well
as through a broad spectrum of related biological
disciplines.

3- Intended Learning Outcome

a- Knowledge and Understanding

At the end of the course, the student should:

a1. Show an understanding of knowledge of the structure
and function of biological macromolecules.
a2. Describe the molecular basis of DNA replication, gene
transcription and translation.
a3. Interpret basis of DNA recombination and its
application in industrial biotechnology.
a4. Associate gene expression to the phenotype of an
organism via understanding of gene and protein
structure and funciton
a5. Collect e a comprehensive knowledge of transcription
factors and their modifications in cancer.
a6. Describe the molecular regulation of prokaryotic and
eukaryotic gene expression

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b- Intellectual Skills

On completion of the course the students will gain:

b1. Apply a conceptual understanding that enables them to
evaluate critically the molecular mechanisms in health
and disease.
b2. Demonstrate an ability to deal with complex issues
both systematically and creatively, and to assemble and
analyse critically a range of information including both
scientific data and library-based material

c- Professional Skills

On completion of the course the students will:

c1. Manipulate their knowledge base of molecular biology
to understand complex problems in biotechnology and
human disease.
c2. Distinguish the theoretical background necessary for
learning the techniques of Molecular Biology of the
Practical Molecular Biology course.
c3. Perform technical presentations suitable for the time,
place and audience

d- General Skills

c4. Analyse the scientific literature and Web resources

effectively
On completion of the course the students will gain:
d1. Practice the ability to work effectively both in an
independent manner through self-direction in planning
and implementing tasks, and also as a member of a
team following discussion and agreement of
procedures.
d2. Qualified to disseminate information effectively both
orally and in written form both to specialist and
nonspecialist Audiences.
d3. Practice the independent learning ability required for
continuing professional development.

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4- Course Content

4-1.Structure and function of DNA,

4-2.Structure and Function of RNA,
4-3.Gene transcription,
4-4.Gene Translation,
4-5.Protein structure and function,
4-6.DNA replication and recombination,
4-7.Regulation of gene expression,
4-8.Polymerases, a6
4-9.Transcription factors,
4-10.RNA maturation and exportation and
4-11.Posttranslational modifications.

5- Teaching and Learning

Methods

Lectures
Power point presentations
Quizzes
Audiovisual methods
Mutual Discussions
Websites...etc

6- Teaching and Learning

Methods for Students with
Special Needs

N/A

7- Student Assessment:

a- Procedures used:

- Quizzes
- Reports
- Mid-term written exam
- Final-term written exam
- Oral Exam

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b- Schedule:

c- Weighing of Assessment:

8- List of Textbooks and

References:

5th week: 1st Quiz

10th week: Mid Term Exam
13th week: 2nd Quiz
17th week: Final and Oral Exam
5% Quiz
15% Mid Term Exam
10% Oral Exam
70% Final Exam

a- Course Notes

Power Point presentation notes

b- Required Books (Textbooks)

Molecular Cell Biology, 5th edition by H. Lodish and

others. (W.H.Freeman, 2003; ISBN: 0716743663).

c- Recommended Books

- Molecular Biology of the Cell. 3rd edition by B. Alberts

and others (1994). (Garland Science, ISBN: 0815316194).
- Molecular Biology of the Gene, 5th edition by Watson
and others. (Pearson Education, 2004)

d- Periodicals, Web Sites, ..., etc.

Course Instructor:

Dr Mahmoud Ibrahim

http://bcs.whfreeman.com/lodish6e/
http://mcb.asm.org/

Head of Department:

Prof. Dr. Prof. Hussein Khamis

Date: 15/1/2015

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