IBM Research:

Increasing the Speed & Scale of Impact

October 21, 2015

Larry L. Light
Business Development Executive
IBM Research

2014 International Business Machines Corporation

IBM Research: Aligned to Lead

Engaging
in new
ways

Cloud
transforming
IT

Data
transforming
industries

Industries &
Engagement
Research

Cloud
Research

Cognitive
Research

Science & Technology

2014 International Business Machines Corporation

Research is the foundation of IBMs future growth

Cloud

Systems

GTS

GBS

Watson
and
Watson
Health

Security

Commerce

Analytics

Intellectual Property

Research

2014 International Business Machines Corporation

IBM Research: Unmatched Talent

3,000 Researchers
$6.2B R&D in 2013

T.J Watson
Austin
Almaden

Ireland
Brazil

Zurich

Haifa
Africa

India

China
Japan
Australia

2014 International Business Machines Corporation

A Culture of Innovation and Leadership

5 Nobel Laureates
Scanning Tunneling Microscope

5 National
Medals of Science

6 Turing Awards

2013 Medal of Honor with

Purple Ribbon
High Temperature
Superconductivity

Electron Tunneling
Effect
DRAM

Millennium Prize
Chieko Asakawa

Nuclear Magnetic
Resonance
Techniques

Basis for
MRI today

10 US National Medals of
Technology
Copper Chip
Technology

High Performance Computing

11 Inductees in National
Inventors Hall of Fame

Excimer Laser

Magnetic Disk Drive

Storage

2014 International Business Machines Corporation

55

External Recognition (Honors and Awards)

Ensures technical vitality

Attracts, retains and energizes
world-class scientists

Generates luster for IBM and IBM
Research

Measurement of our Technical
contributions

2014 International Business Machines Corporation

6 6

Leading in key research disciplines

Behavioral
Science

Materials
Science

Chemistry

Mathematical
Science

Computer
Science

Electrical
Engineering

Physics

Service
Science
Science &
Business &
Engineering Management
Technology
Innovation

Business
Innovation

Social
Innovation

Demand
Innovation

Social &
Cognitive
Sciences

2014 International Business Machines Corporation

Economics
& Markets

22nd

21st year of patent leadership

7000

6809

Number of Patents

>5x

>10x

>40x

2660

1775

1455

1360
540

525

442

374

156

0
IBM

Microsoft

2014 International Business Machines Corporation

Apple

Intel

HP

Amazon

Oracle

Symantec

EMC

Accenture

Source: IFI CLAIMS Patent Services

8

Explosion of Data across all Industries

Cloud

Exabytes

35
30
25
20
15
10
5
0
2009 2010 2011 2012 2013 2014 2015 2016 2017
Source: IDCs sixth annual study of the digital universe (2012)

2014 International Business Machines Corporation

Multimedia
Consumer
oriented IoT
Manufacturing &
Enterprise IoT
Genomic
Text data
Structured
Other

Mobile

Social
Internet of
Things

IBM has launched the Next Era of Computing

Cognitive Systems
Era
Programmable
Systems Era
Tabulating
Systems Era

2014 International Business Machines Corporation

10

Journey to Watson: a deep foundation in computer science

Natural
Language
Processing

Question
Answering
Technology

2014 International Business Machines Corporation

High
Performance
Computing

Knowledge
Representation
and
Reasoning

Machine
Learning

Unstructured
Information
Management

11

Key technologies for the next era of computing

Context and
Learning
Visual Analytics
and Interaction
Software
Defined
Environment
Data-centric
Systems
Atomic and
Nano-scale

12 2014 International Business Machines Corporation

Cognitive
Computing

12

Transforming industries with Systems of Insight

Financial service

Industrial

Financial fraud
detection

Renewable energy
reserve management

Financial transactions

Supply/demand history

Social network

Physical data

Retail

Life sciences

360o customer insight

New medicine discovery

Purchase history

Drug/genome database

Social media

Clinical experience

2014 International Business Machines Corporation

13

A cross industry biospace revolution

Omics Big Data analytics

Healthcare:
Genomic Medicine

Modeling (Systems Biology)

Agriculture and Food

Bioengineering (Synthetic Biology)

Energy, Environment,
and Natural resources

Chemical, Pharmaceutical
and Consumer Products

Personalized
and preventive
healthcare

Personalized
nutrition

Sustainable biofuel
production

Green Chemistry:
Bio-plastics and
enzymes

Biosensors and
bioelectronics

Salt, drought,
diseases tolerant
crop

Rare earth, precious

metal collection

Functional such as
spider silk and tires

Carbon capture and

Bioremediation for
clean air, water and
soil

Cosmetics and
personal care
products

Accelerated drug
discovery,
development, and
manufacturing

2014 International Business Machines Corporation

Efficient, safe, and

healthy meat

14

Collaborators/Clients in Ag Genomics

Improving cacao, avocado quality

Discovering markers for selection, utilizing genetic and
phenotypic variation in mapping populations

 Improving robustness of bio-energy grasses

Discovering genes for drought, flood, salt stress resistance

Improving quality of cultivated plants

Generating smarter breeding decisions, guided by
accurate genomic selection methods and simulations

2014 International Business Machines Corporation

15

Computational Biology Research at IBM

the intersection of Information Technology and Life Sciences

Managing and Analyzing the Data Explosion

Systems: Workflow acceleration, appliance,
Genomics

pharma, diagnostics

Software: Data integration for translational research

academic medical

Analytics: Watson, IRiS, iXORA, EUResist, CliG,

agriculture, food

Bioinformatics, Neuroinformatics

Predicting Biological Outcomes with Large Scale Computing

Deep Computing

pharma
medical devices

food

Dealing with Complexity

food, pharma
for LS

Bio-nanotechnology
MRL, Nanotechnology

2014 International Business Machines Corporation

Nanochannels, Biosensing,

diagnostics, medical devices

16

An IBM Research-client Partnership to Drive Transformation

Cognitive Computing for Materials Industry
Accelerated
Research & Development

Design material for desired properties

Leverage Known Solutions
Access all relevant IP and knowledge
Improve for Critical Factors

Faster time to solution

Optimized Manufacturing
Production and Costs

Analyze data for optimum production

Learn from similar plants, processes
Improve operational efficiency
Monitor and assure compliance

Lower cost to manufacture

Optimal solution for

client or market

Map client requirements to available and

known solutions

Optimize price performance availability

Find adjacent solutions and use cases
Maximize value to client

HPC Industry Cloud

17

2015 IBM Corporation

23 October 2015

IBM Research

Foundational Technology for Strategic Partnerships

We are working towards cognitive systems that combine data and prediction to help discover new
materials and improve existing processes and materials
What can be calculated:
Predictive models
Simulations, statistics, correlations

Cognitive Systems

New materials
New capabilities
New solutions

What is known:
Papers, patents, reports
Experiments, extraction, similarity
18

2015 IBM Corporation

23 October 2015

IBM Research

Nanomedicine: Bold Agenda, three major thrust enabled by macromolecular

therapeutics and therapeutic carriers
Cancer research
Infectious Disease
Aging related diseases
Leverage polymer chemistry expertise
to encapsulate, deliver and release
therapeutics: efficacious delivery and
synergistic delivery to mitigate tumor
and tumor stem cells to prevent metastasis.
Broad impact across many institutes and
hospitals in Cambridge

Drug resistant bacteria and biofilms are

two of the grand challenges of this decade.
Central to this challenge is the development
of macromolecular therapeutics that preclude
resistance. Moreover, since the advent of viruses
such as Ebola, Marburg, Chikungunya, IBM has
developed novel strategies to prevent such
Infections and mitigate resistance development.

Aging associated diseases are pervasive and

include cardiovascular disease, arthritis,
cataracts, type 2 diabetes and brain related
such as Alzheimers and Parkinsons diseases.
IBM will leverage technologies developed
from thrust 1 and 2 to enable drug delivery
across the blood-brain-barrier and to treat heart
disease, arthritis, hip and knee replacements.

36 nm

Nanomedicine

Loaded nanoparticles
navigate the blood-brainBarrier (Alzheimers etc)

IBM will bring expertise in polymer chemistry and bioinformatics to address critical issues
associated with encapsulation, transport, targeting and delivery of biologics, drugs and genes to
address the demanding needs of the industry
2014 International Business Machines Corporation

19

Key antimicrobial challenges for agriculture

Citrus greening- Candidatus Liberibacter
Huanglongbing yellow dragon disease
Largely seen in Asia until 2004 first report
in Western hemisphere in Brazil
Symptoms
Yellow shoots
Twig dieback
Mottling and chlorosis
Reduced fruit size and quality
Bitter fruit, low juice yield
Transmission of Candidatus liberibactera
Citrus psyllid during phloem feeding
Plant grafts
Current treatment:
Eradication and replacement
Thermotherapy of graftwood
Chemotherapy with tetracycline or penicillin
Vector control with dimethoate, carbofuran,
methomyl, or malathion sprays
2014 International Business Machines Corporation

20

Jefferson Project: Study of Lake George

Survey Data
Bathymetry (depth)
Topography (watershed)

Sensor
Data
Physical
Current/flow
Temperature
Pressure
Turbidity
Chemical
Dissolved O2
Salinity
Nitrates
Phosphates
Chlorophyll
Biological
Algae
Cyanobacteria
Diatoms
Phytoplankton
Zooplankton

Coupled
Models
Weather

Runoff

Circulation

Food Web

Rising NaCl concentration

Proliferation of invasive species

Flint River Partnership

The Flint River Basin Partnership is an agricultural water conservation initiative pioneered by the Flint River Soil and Water
Conservation District, USDA's Natural Resources Conservation Service, and The Nature Conservancy. The partnership was
designed to help farmers in the Lower Flint River Basin of Georgia conserve water using new and innovative irrigation
technology

ESTABLISHING A IBM-SYNGENTA JOINT RESEARCH FRAMEWORK

Life Sciences

Genomics
Biology/Modelling
Food Safety

Crop Health

Chemistry/Materials
Nanoscience
Accelerated
Discovery

Insights

Digital Farming

Mapping
Weather
Yield Prediction
Precision Irrigation

Social Analytics
Marketing Insights
Security
Competitive
Regulatory

2015 IBM Corporation