sulfadiazine: 2-4mg po QID or TID

sulfamethoxazole *(Gantanol)*: 1gm po BIDused to treat: UTI, meningitis, Otitis Media.

sulfasalazine *(Azulfidine)*: 500mg QIDused to treat: Ulcerative colitis
trimethroprim (TMP) & sulfamethoxazole (SMZ) *(Bactrim, Septra)*: 160mg/800mg po
q 12hrsused to treat: UTI, Acute Otitis Media, Traveler's Diarrhea
Silver sulfadiazine *(Silvadine Cream)*:
used to treat: 2nd & 3rd degree burns
Aplastic anemia: anemia due to red blood cells production in the bone marrow.
Contraindicate: To warn against a particular treatment or activity.
What are sulfonamides? (sulfa)

theyre effective against infection

antibacterial agent is active against bacteria

How do sulfonamides act or work? Inhibit the activity of folic acid in bacterial cell
metabolism
slow the rate of bacterial multiplication
What are sulfonamides used for?
bacteria

Control urinary tract infections caused by certain

treat infections cause by second and third degree burns

What are some adverse reactions of sulfonamides? urine and skin can take on an orange
yellow color, crystalluria, photosensitivity
what are some hypersensitivity reactions to sulfonamides? pruritus, urticarial (hives),
skin eruptions.
What should you assess a diabetic pt for when putting them on sulfonamides?
hypoglycemic reaction
Good and bad of cranberries They can prevent and relieve symptoms of utis and in
combination with antibiotics they can suppress utis.
Extremely large doses can cause gastrointestinal disturbances
What are some nursing diagnoses of pts on sulfonamides? Impaired Urinary Elimination
related to effect on the bladder from the sulfonamides

Impaired Skin Integrityrelated to burns, photosensitivity, or severe allergic reaction to

the sulfonamides
Risk for Secondary Infectionrelated to lowered white blood cell count resulting from
sulfonamide therapy
Should sulfonamides be given with meals? on an empty stomach so 1 hour before or 2
hours after meals. Gastrointestinal irritation: Give sulfasalazine with food or immediately
after meals; drink at least eight large glasses of water each day
What should you do if pt has impaired urinary elimination? measure pts intake and output
every 8 hours and notify dr if urinary output decreases or pt fails to increase intake
What should you watch for on gerontologic pts on sulfonamides? Renal impairment,
and you should increase fluid intake upto 2000 mL
What are some medications a burn pt might use?

mafenide or silver sulfadiazine

You would apply drug 1/16 inch thick

Names of SULFONAMIDES? Special considerations for each?: Sulfadiazine,
Sulfasalazine (may cause skin and urine to turn orange-yellow), Sulfisoxazole (can be
combined with trimethoprim to make a urinary anti-infective).
Topical preparations: Mafenide (can cause facial edema), and silver sulfadiazine (may
cause skin discoloration).

what are signs and symptoms of thrombocytopenia? easy bruising and unusual bleeding
after moderate to slight trauma to the skin. have pt use soft bristled tooth brush and
reports signs to dr immediately
What should input and output be when pt is on sulfonamides?
output should be at least 1200 mL

intake 2000mL and