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Lymphoma Symptoms,
Causes and Treatments
Lymphoma is a type of cancer that begins in immune
system cells called lymphocytes. Like other cancers,
lymphoma occurs when lymphocytes are in a state of
uncontrolled cell growth and multiplication.
Lymphocytes are white blood cells that move
throughout the body in a fluid called lymph. They are
transported by a network of vessels that make up the
lymphatic system, part of the immune system. The
lymphatic system - whose job it is to fight infections or
anything else that threatens the body - is also
comprised of lymph nodes that exist throughout the
body to filter the lymph that flows through them. The
lymph nodes swell and tenderize when a large
number of microbial organisms collect inside of them,
indicating local infection.
There are two primary types of lymphocytes: B cells
and T cells. Both are designed to recognize and
destroy infections and abnormal cells. B cells produce
proteins that travel throughout the body, attaching
themselves to infectious organisms and abnormal
cells and alerting the immune system that the
pathogen needs to be destroyed. T cells actually kill
the pathogens directly and serve a function in
regulating the immune system from over- or underactivity.
Interesting articles
What is cancer? What causes cancer?
What is function of the lymph nodes?
Lymphoma occurs when lymphocyte B or T cells
transform and begin growing and multiplying
uncontrollably. Abnormal lymphocytes collect in one or
more lymph nodes or in lymph tissues such as the
spleen or tonsils, and eventually they form a mass of
cells called a tumor. Tumors grow and invade the
space of surrounding tissues and organs, depriving
them of oxygen and nutrients.
If abnormal lymphocytes travel from one lymph node
to the next or to other organs, the cancer can spread
or metastasize. Lymphoma development outside of
lymphatic tissue is called extranodal disease.
In the United States each year, some 54,000 people
are diagnosed with NHL and 7,000 are diagnosed HL.
It is the most common type of blood cancer in the US.
The European Union sees over 50,000 cases of NHL
every year.
How is lymphoma classified?
There are two types of lymphoma: Hodgkin
lymphoma (HL, also called Hodgkin's disease) and
non-Hodgkin lymphoma (NHL). Both HL and NHL
can occur in the same places and have similar
X-rays
Lymphangiogram
Gallium scan