Total number of hours (per semester) from

education plan
101

THE SHEET OF DISCIPLINE

Name of Discipline
Year of study

HISTOLOGY
II

Semester *

II

Type of the final evaluation (E / V /

C)

The regime of the discipline (C - Compulsory , O - Optional, F

Ob Credits
Facultative)
Total hours of individial
Total hours per
Total hours from education plan
56
45
study
semester
Coordinator of the teaching
Professor Irina Draga Cruntu
activity
* If the discipline has more semesters of study, should fill in for each semester
Total
Faculty

MEDICINE

Department

MORPHO-FUNCTIONAL
SCIENCES

Profile

MEDICINE

Specialisation

MEDICINE

C**
56

28

E2
7
101

L
28

** C course, L laboratories activities, P

project or practical works

Minimum knowledge needed by students attending the course notions / practical works notions
Notions of cellular and molecular biology (cell, nucleus, cell organelles), based landmarks of anatomy,
physiology and biochemistry

Objectives of discipline
The training of the students regarding tissue and systemic structure of the human organism, with direct
correspondence in functionality, through:
(i)
theoretical notions/concepts which cover the fundamental characterization of the main tissues
and systems;
(ii)
practical activity which aims the identification of microscopic elements and formulation of
organ diagnostic.

Analytical Curriculum course

Hours

1. Immune system
General organization: primary and secondary lymphoid organs (definition,
functions), immunity types. Primary lymphoid organs: thymus (histoarchitectony,
cell populations, vascularization, blood-thymus barrier, histophysiology),
hematogenous bone marrow (histoarchitectony, histophysiology).
2. Immune system
Secondary lymphoid organs: lymph node (histoarchitectony, lymphatic sinuses,
histophysiology), spleen (histoarchitectony, vascularization, histophysiology),
mucosa-associated lymphoid tissue tonsils (histoarchitectony, histophysiology)
3.Endocrine system
Hypophysis (histoarchitectony, hypothalamic hypophyseal portal system,
adenohypophysis cell types, neurohypophysis cell types, histophysiology).
Pineal gland (histoarchitectony, cell types, histophysiology)
4. Endocrine system
Thyroid gland (histoarchitectony, cell types, histophysiology). Parathyroid gland
(histoarchitectony, cell types, histophysiology). Adrenal gland (histoarchitectony,
cell types, histophysiology).
5. Digestive system
Oral cavity: lip, tongue, mucosa types (histoarchitectony), tooth (histogenesis, the
structure of adult tooth). General structure of the gastrointestinal tract.
6. Digestive system
Pharynx (histoarchitectony, histophysiology). Esophagus, eso-gastric junction
(histoarchitectony, histophysiology). Stomach (histoarchitectony: cardial region,
fundic region, pyloric region, histophysiology). Small intestine (histoarchitectony:
duodenum, jejunum, ileum; histophysiology). Large intestine (histoarchitectony:
colon, appendix, cecum; histophysiology)
7. Digestive system
Adnexal glands of digestive system: liver (histoarchitectony: vascularization,
hepatic lobulation; cell types, histophysiology), gall bladder (histoarchitectony,
histophysiology), pancreas (histoarchitectony: exocrine and endocrine component,
histophysiology), salivary glands (types, histoarchitectony, histophysiology)
8. Respiratory system
General organization. Conducting segment: nasal cavities, nasopharynx, larynx,
trachea, bronchi, bronchioles (histoarchitectony, histophysiology). Respiratory
segment: bronchioles, alveoli (histoarchitectony, histophysiology). Pulmonary
morphofunctional units.
9. Excretory system
General organization. Kidney (histoarchitectony, histophysiology). Urinary ducts:
ureter, urinary bladder, urethra (histoarchitectony, histophysiology)
10. Female genital system
General organization. Ovary (histoarchitectony, ovarian follicles in evolution and
involution, histophysiology: ovarian cycle). Fallopian tubes (histoarchitectony,
histophysiology).

11. Female genital system

Vagina
(histoarchitectony,
histophysiology).
Uterus
(histoarchitectony,
histophysiology: endometrial cycle, pregnancy). Placenta (structure in the evolution
of pregnancy, histophysiology).
12. Mammary gland. Skin
Mammary gland (histoarchitectony, histophysiology). Skin (histoarchitectony,
histophysiology). Sensorial receptors (free and encapsulated nerve endings)
13. Male genital system
General organization. Testis (histoarchitectony, cell types, histophysiology).
Extratesticular genital ducts (histoarchitectony, histophysiology). Seminal vesicles
(histoarchitectony, histophysiology). Prostate (histoarchitectony, histophysiology)
14. Special sense organs
Photoreceptor system (histoarchitectony, histophysiology). Audioreceptor system
(histoarchitectony, histophysiology).

Analytical Curriculum laboratory

1. Immune system
Primary lymphoid organs: thymus, bone marrow. Secondary lymphoid organs: Tindependent zones (primary lymphoid follicle, secondary lymphoid follicle), Tdependent zones
2. Immune system
Secondary lymphoid organs: lymph node, spleen, MALT
3. Endocrine system
Endocrine glands: thyroid gland, parathyroid gland, adrenal gland, endocrine
pancreas
4. Digestive system
Oral cavity: lip, tongue, tooth bud, adult tooth. Esophagus, eso-gastric junction.
5. Digestive system
Stomach: pyloric region, fundic region. Small intestine: duodenum, jejunum, ileum;
large intestine: colon, appendix
6. Digestive system
Adnexal glands of digestive system: liver, pancreas, salivary glands, gall bladder
7. Recapitulation

8. Respiratory system
Trachea, lung
9. Excretory system
Kidney, urinary bladder
10. Female genital system
Ovary, fallopian tube, uterus (proliferative phase endometrium, secretory phase
endometrium), uterine cervix, placenta (I trimester, II-III trimester).
11. Mammary gland. Skin
Mammary gland (in repose period, in lactation), skin (epidermis thick skin and
thin skin, dermis superficial and deep, skin appendages hair follicle, sweat
gland, sebaceous gland)

2
2

2
2

2
2

2
2

12. Male genital system

Testis, intra- and extratesticular ducts, seminal vesicle, prostate
13. Special sense organs
Sensorial receptors (free and encapsulated nerve endings), photoreceptor system
(eye retina, lens, cornea), audioreceptor system (organ of Corti)
14. Recapitulation.

2
2

Competences
1. Theoretical characterization and microscopic identification of the fundamental tissues of the organism
2. Theoretical characterization and microscopic identification of specific structures which form the
systems
3. Formulation of the organ diagnostic

For the final mark will be considered:

- the answers at the final exam:

MCQ
practical exam

Weight expressed in percent

(Total = 100%)
50%
35%

- final answers at the practical laboratories

- continuous testing during the semester continue testing

15%

- activities like homework / referrals / essay / translation /

projects

- other activities (SPECIFY) :

Describe the practical modality for the final evaluation:

Writing exam MCQ (75 multiple choice questions) - Type complement simple
Practical exam oral

Estimate the total hours (hours per semester) for the individual activities of the student
(fill in with 0 the activities which are not requested)
7
1. Read-in and learning the curs notes
8. Preparing oral presentations
0
7

9. Preparing the final

examination

15

3. The study of the minimal suggested

bibliography

10

10. Consultations

4. Supplementary documentation in library

11. Reference material

12. Reference material on

Internet

2. Learning using the textbook, courses

5. Specific activity for seminary / laboratory

6. Achieving of homework, report, essay,

translation

13. Other activities ...

7. Preparing the control papers

14. Other activities ...

TOTAL hours of individual study =

45

Compulsory bibliography:
Amalinei C, Balan R, Cotutiu C, Histology Microscopic Diagnosis of Organs, Ed.
Cantes, 2000
Luca CI, Histology Organs and Systems, Ed. Dosoftei Iai, 2000
Ross MH, Pawlina W, Histology, A Text and Atlas, 6th. ed, Wolters Kluwer, Lippincott
Williams & Wilkins, Philadelphia, 2011
Supplimentary bibliography - Histology
Gartner L.P., Hiatt I. L., Color Textbook of Histology, Saunders Elsevier, Philadelphia,
third edition, 2007
Junqueira LC, Carneiro J, Basic Histology. Text and Atlas, 11th. ed., McGraw-Hill
Companies, New-York, 2005

Date of fill in: 2012

The signature of the coordinator of

the teaching activity
Prof. dr. Irina-Draga Cruntu